Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1α pathway

Biochemical and Biophysical Research Communications

Volumn 413, Issue 2, 2011, Pages 299-305

  Liu, Ling Zhi ^a   Jing, Yi ^a   Jiang, Lisa L ^b   Jiang, Xiu E ^b   Jiang, Yue ^a   Rojanasakul, Yongyut ^b   Jiang, Bing Hua ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Acacetin; AKT; Angiogenesis; HIF 1; VEGF

Indexed keywords

ACACETIN; ANGIOGENESIS INHIBITOR; BETA ACTIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 1BETA; MESSENGER RNA; NATURAL PRODUCT; PROTEIN KINASE B; VASCULOTROPIN;

ANIMAL CELL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; CANCER CELL; CANCER INHIBITION; CONTROLLED STUDY; DRUG TARGETING; FEMALE; IN VIVO STUDY; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; TRANSCRIPTION INITIATION; TUMOR VASCULARIZATION;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL PROLIFERATION; CHICK EMBRYO; FEMALE; FLAVONES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; NEOVASCULARIZATION, PATHOLOGIC; OVARIAN NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; TRANSCRIPTIONAL ACTIVATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80053097574     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.08.091     Document Type: Article

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