메뉴 건너뛰기




Volumn 158, Issue 4, 2011, Pages 214-224

Gefitinib attenuates transforming growth factor-β1-activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CYCLIN D1; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 80053001586     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2011.06.002     Document Type: Article
Times cited : (11)

References (42)
  • 1
    • 66449119643 scopus 로고    scopus 로고
    • Renal tubulointerstitial fibrosis: Common but never simple
    • T.D. Hewitson Renal tubulointerstitial fibrosis: common but never simple Am J Physiol Renal Physiol 296 2009 F1239 F1244
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Hewitson, T.D.1
  • 2
    • 33845262861 scopus 로고    scopus 로고
    • Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-β pathway
    • DOI 10.1038/sj.ki.5001846, PII 5001846
    • G. Wolf Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway Kidney Int 70 2006 1914 1919 (Pubitemid 44863378)
    • (2006) Kidney International , vol.70 , Issue.11 , pp. 1914-1919
    • Wolf, G.1
  • 3
    • 33750712380 scopus 로고    scopus 로고
    • Renal fibroblasts and myofibroblasts in chronic kidney disease
    • DOI 10.1681/ASN.2006050420
    • F. Strutz, and M. Zeisberg Renal fibroblasts and myofibroblasts in chronic kidney disease J Am Soc Nephrol 17 2006 2992 2998 (Pubitemid 44707759)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.11 , pp. 2992-2998
    • Strutz, F.1    Zeisberg, M.2
  • 4
    • 35048875855 scopus 로고    scopus 로고
    • TGF-β signaling: A tale of two responses
    • DOI 10.1002/jcb.21501
    • R.A. Rahimi, and E.B. Leof TGF-beta signaling: a tale of two responses J Cell Biochem 102 2007 593 608 (Pubitemid 47557414)
    • (2007) Journal of Cellular Biochemistry , vol.102 , Issue.3 , pp. 593-608
    • Rahimi, R.A.1    Leof, E.B.2
  • 5
    • 75749131647 scopus 로고    scopus 로고
    • Narrative review: Fibrotic diseases: Cellular and molecular mechanisms and novel therapies
    • J. Rosenbloom, S. Castro, and S. Jimenez Narrative review: fibrotic diseases: cellular and molecular mechanisms and novel therapies Ann Intern Med 152 2010 159 166
    • (2010) Ann Intern Med , vol.152 , pp. 159-166
    • Rosenbloom, J.1    Castro, S.2    Jimenez, S.3
  • 6
    • 58149213801 scopus 로고    scopus 로고
    • Non-Smad pathways in TGF-beta signaling
    • Y.E. Zhang Non-Smad pathways in TGF-beta signaling Cell Res 19 2009 128 139
    • (2009) Cell Res , vol.19 , pp. 128-139
    • Zhang, Y.E.1
  • 7
    • 33746889808 scopus 로고    scopus 로고
    • A comprehensive pathway map of epidermal growth factor receptor signaling
    • K. Oda, Y. Matsuoka, A. Funahashi, and H. Kitano A comprehensive pathway map of epidermal growth factor receptor signaling Mol Syst Biol 1 2005 1 17
    • (2005) Mol Syst Biol , vol.1 , pp. 1-17
    • Oda, K.1    Matsuoka, Y.2    Funahashi, A.3    Kitano, H.4
  • 8
    • 58149376976 scopus 로고    scopus 로고
    • The epidermal growth factor receptor ligands at a glance
    • M.R. Schneider, and E. Wolf The epidermal growth factor receptor ligands at a glance J Cell Physiol 218 2009 460 466
    • (2009) J Cell Physiol , vol.218 , pp. 460-466
    • Schneider, M.R.1    Wolf, E.2
  • 9
    • 4644286909 scopus 로고    scopus 로고
    • Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition
    • H. Francois, S. Placier, and M. Flamant Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition FASEB J 18 2004 926 928
    • (2004) FASEB J , vol.18 , pp. 926-928
    • Francois, H.1    Placier, S.2    Flamant, M.3
  • 11
    • 1542343906 scopus 로고    scopus 로고
    • Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation
    • DOI 10.1096/fj.03-0699com
    • G.R. Grotendorst, H. Rahmanie, and M.R. Duncan Combinatorial signaling pathways determine fibroblast proliferation and myofibroblast differentiation FASEB J 18 2004 469 479 (Pubitemid 38326303)
    • (2004) FASEB Journal , vol.18 , Issue.3 , pp. 469-479
    • Grotendorst, G.R.1    Rahmanie, H.2    Duncan, M.R.3
  • 12
    • 33646594714 scopus 로고    scopus 로고
    • TGF-beta1-induced EMT can occur independently of its proapoptotic effects and is aided by EGF receptor activation
    • N.G. Docherty, O.E. O'Sullivan, and D.A. Healy TGF-beta1-induced EMT can occur independently of its proapoptotic effects and is aided by EGF receptor activation Am J Physiol Renal Physiol 290 2006 F1202 F1212
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Docherty, N.G.1    O'Sullivan, O.E.2    Healy, D.A.3
  • 14
    • 62749091607 scopus 로고    scopus 로고
    • The role of stress-activated protein kinase signaling in renal pathophysiology
    • F.Y. Ma, J. Liu, and D.J. Nikolic-Paterson The role of stress-activated protein kinase signaling in renal pathophysiology Braz J Med Biol Res 42 2009 29 37
    • (2009) Braz J Med Biol Res , vol.42 , pp. 29-37
    • Ma, F.Y.1    Liu, J.2    Nikolic-Paterson, D.J.3
  • 15
    • 76949104807 scopus 로고    scopus 로고
    • Mechanisms of transforming growth factor beta/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts
    • S. He, X. Liu, and Y. Yang Mechanisms of transforming growth factor beta/Smad signalling mediated by mitogen-activated protein kinase pathways in keloid fibroblasts Br J Dermatol 162 2010 538 546
    • (2010) Br J Dermatol , vol.162 , pp. 538-546
    • He, S.1    Liu, X.2    Yang, Y.3
  • 16
    • 70350244839 scopus 로고    scopus 로고
    • Comparative proteome analysis of TGF-beta1-induced fibrosis processes in normal rat kidney interstitial fibroblast cells in response to ascofuranone
    • J.H. Kang, H.J. Cho, and I.S. Lee Comparative proteome analysis of TGF-beta1-induced fibrosis processes in normal rat kidney interstitial fibroblast cells in response to ascofuranone Proteomics 9 2009 4445 4456
    • (2009) Proteomics , vol.9 , pp. 4445-4456
    • Kang, J.H.1    Cho, H.J.2    Lee, I.S.3
  • 17
    • 38549128163 scopus 로고    scopus 로고
    • Ligand release-independent transactivation of epidermal growth factor receptor by transforming growth factor-beta involves multiple signaling pathways
    • C.K. Joo, H.S. Kim, and J.Y. Park Ligand release-independent transactivation of epidermal growth factor receptor by transforming growth factor-beta involves multiple signaling pathways Oncogene 27 2008 614 628
    • (2008) Oncogene , vol.27 , pp. 614-628
    • Joo, C.K.1    Kim, H.S.2    Park, J.Y.3
  • 18
    • 0035096603 scopus 로고    scopus 로고
    • Role of receptor for advanced glycation end-product (RAGE) and the JAK/STAT-signaling pathway in AGE-induced collagen production in NRK-49F cells
    • J.S. Huang, J.Y. Guh, and H.C. Chen Role of receptor for advanced glycation end-product (RAGE) and the JAK/STAT-signaling pathway in AGE-induced collagen production in NRK-49F cells J Cell Biochem 81 2001 102 113
    • (2001) J Cell Biochem , vol.81 , pp. 102-113
    • Huang, J.S.1    Guh, J.Y.2    Chen, H.C.3
  • 19
    • 59349108429 scopus 로고    scopus 로고
    • Transcriptional regulation of the cyclin D1 gene at a glance
    • E.A. Klein, and R.K. Assoian Transcriptional regulation of the cyclin D1 gene at a glance J Cell Sci 121 2008 3853 3857
    • (2008) J Cell Sci , vol.121 , pp. 3853-3857
    • Klein, E.A.1    Assoian, R.K.2
  • 20
    • 33750019223 scopus 로고    scopus 로고
    • Proteomic analysis for the assessment of different lots of fetal bovine serum as a raw material for cell culture. Part IV. Application of proteomics to the manufacture of biological drugs
    • DOI 10.1021/bp060121o
    • X. Zheng, H. Baker, and W.S. Hancock Proteomic analysis for the assessment of different lots of fetal bovine serum as a raw material for cell culture. Part IV. Application of proteomics to the manufacture of biological drugs Biotechnol Progr 22 2006 1294 1300 (Pubitemid 44568803)
    • (2006) Biotechnology Progress , vol.22 , Issue.5 , pp. 1294-1300
    • Zheng, X.1    Baker, H.2    Hancock, W.S.3    Fawaz, F.4    McCaman, M.5    Pungor Jr., E.6
  • 21
    • 0036894194 scopus 로고    scopus 로고
    • Inhibition of the JAK/STAT signaling pathway prevents the high glucose-induced increase in TGF-β and fibronectin synthesis in mesangial cells
    • X. Wang, S. Shaw, F. Amiri, D.C. Eaton, and M.B. Marrero Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase in tgf-beta and fibronectin synthesis in mesangial cells Diabetes 51 2002 3505 3509 (Pubitemid 35403457)
    • (2002) Diabetes , vol.51 , Issue.12 , pp. 3505-3509
    • Wang, X.1    Shaw, S.2    Amiri, F.3    Eaton, D.C.4    Marrero, M.B.5
  • 23
    • 0032911889 scopus 로고    scopus 로고
    • Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts
    • N. Takuwa, Y. Fukui, and Y. Takuwa Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts Mol Cell Biol 19 1999 1346 1358 (Pubitemid 29046876)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.2 , pp. 1346-1358
    • Takuwa, N.1    Fukui, Y.2    Takuwa, Y.3
  • 24
    • 0034836953 scopus 로고    scopus 로고
    • EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin
    • C. Santiskulvong, J. Sinnett-Smith, and E. Rozengurt EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin Am J Physiol Cell Physiol 281 2001 C886-C98
    • (2001) Am J Physiol Cell Physiol , vol.281
    • Santiskulvong, C.1    Sinnett-Smith, J.2    Rozengurt, E.3
  • 26
    • 0037608715 scopus 로고    scopus 로고
    • Biphasic role of TGF-β1 in signal transduction and crosstalk
    • DOI 10.1002/jcp.10243
    • C.E. Wenner, and S. Yan Biphasic role of TGF-beta1 in signal transduction and crosstalk J Cell Physiol 196 2003 42 50 (Pubitemid 36676441)
    • (2003) Journal of Cellular Physiology , vol.196 , Issue.1 , pp. 42-50
    • Wenner, C.E.1    Yan, S.2
  • 27
    • 26444515531 scopus 로고    scopus 로고
    • Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts
    • DOI 10.1007/s00408-004-2534-z
    • M. Hetzel, M. Bachem, D. Anders, G. Trischler, and M. Faehling Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblasts Lung 183 2005 225 237 (Pubitemid 41428095)
    • (2005) Lung , vol.183 , Issue.4 , pp. 225-237
    • Hetzel, M.1    Bachem, M.2    Anders, D.3    Trischler, G.4    Faehling, M.5
  • 28
    • 63349085785 scopus 로고    scopus 로고
    • Efficient inhibition of fibroblast proliferation and collagen expression by ERK2 siRNAs
    • F. Li, C. Fan, T. Cheng, C. Jiang, and B. Zeng Efficient inhibition of fibroblast proliferation and collagen expression by ERK2 siRNAs Biochem Biophys Res Comm 382 2009 259 263
    • (2009) Biochem Biophys Res Comm , vol.382 , pp. 259-263
    • Li, F.1    Fan, C.2    Cheng, T.3    Jiang, C.4    Zeng, B.5
  • 29
    • 30044435231 scopus 로고    scopus 로고
    • Proliferation of pulmonary interstitial fibroblasts is mediated by transforming growth factor-β1-induced release of extracellular fibroblast growth factor-2 and phosphorylation of p38 MAPK and JNK
    • DOI 10.1074/jbc.M510441200
    • N. Khalil, Y.D. Xu, R. O'Connor, and V. Duronio Proliferation of pulmonary interstitial fibroblasts is mediated by transforming growth factor-beta1-induced release of extracellular fibroblast growth factor-2 and phosphorylation of p38 MAPK and JNK J Biol Chem 280 2005 43000 43009 (Pubitemid 43049264)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.52 , pp. 43000-43009
    • Khalil, N.1    Xu, Y.D.2    O'Connor, R.3    Duronio, V.4
  • 30
    • 57649223738 scopus 로고    scopus 로고
    • Joint requirement for Rac and ERK activities underlies the mid-G1 phase induction of cyclin D1 and S phase entry in both epithelial and mesenchymal cells
    • E.A. Klein, L.E. Campbell, D. Kothapalli, A.K. Fournier, and R.K. Assoian Joint requirement for Rac and ERK activities underlies the mid-G1 phase induction of cyclin D1 and S phase entry in both epithelial and mesenchymal cells J Biol Chem 283 2008 30911 30918
    • (2008) J Biol Chem , vol.283 , pp. 30911-30918
    • Klein, E.A.1    Campbell, L.E.2    Kothapalli, D.3    Fournier, A.K.4    Assoian, R.K.5
  • 31
    • 3142546336 scopus 로고    scopus 로고
    • Cyclin-dependent kinases regulate the antiproliferative function of Smads
    • DOI 10.1038/nature02650
    • I. Matsuura, N.G. Denissova, and G. Wang Cyclin-dependent kinases regulate the antiproliferative function of Smads Nature 430 2004 226 231 (Pubitemid 38902433)
    • (2004) Nature , vol.430 , Issue.6996 , pp. 226-231
    • Matsuura, I.1    Denissova, N.G.2    Wang, G.3    He, D.4    Long, J.5    Liu, F.6
  • 32
    • 34247550969 scopus 로고    scopus 로고
    • RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; Implications for idiopathic pulmonary fibrosis
    • K.L. Watts, E. Cottrell, P.R. Hoban, and M.A. Spiteri RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis Respir Res 7 2006 88
    • (2006) Respir Res , vol.7 , pp. 88
    • Watts, K.L.1    Cottrell, E.2    Hoban, P.R.3    Spiteri, M.A.4
  • 33
    • 67650673812 scopus 로고    scopus 로고
    • Improvement of renal hemodynamics during hypertension-induced chronic renal disease: Role of EGF receptor antagonism
    • F. Helle, C. Jouzel, and C. Chadjichristos Improvement of renal hemodynamics during hypertension-induced chronic renal disease: role of EGF receptor antagonism Am J Physiol Ren Physiol 297 2009 F191-F9
    • (2009) Am J Physiol Ren Physiol , vol.297
    • Helle, F.1    Jouzel, C.2    Chadjichristos, C.3
  • 34
    • 70349808182 scopus 로고    scopus 로고
    • Noncanonical transforming growth factor beta signaling in scleroderma fibrosis
    • M. Trojanowska Noncanonical transforming growth factor beta signaling in scleroderma fibrosis Curr Opin Rheumatol 21 2009 623 629
    • (2009) Curr Opin Rheumatol , vol.21 , pp. 623-629
    • Trojanowska, M.1
  • 36
    • 24644476507 scopus 로고    scopus 로고
    • Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-β: Implications for carcinogenesis
    • DOI 10.1038/sj.onc.1208928, PII 1208928
    • D. Javelaud, and A. Mauviel Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis Oncogene 24 2005 5742 5750 (Pubitemid 43086134)
    • (2005) Oncogene , vol.24 , Issue.37 , pp. 5742-5750
    • Javelaud, D.1    Mauviel, A.2
  • 37
    • 44449085517 scopus 로고    scopus 로고
    • Hyaluronan facilitates transforming growth factor-beta1-mediated fibroblast proliferation
    • S. Meran, D.W. Thomas, and P. Stephens Hyaluronan facilitates transforming growth factor-beta1-mediated fibroblast proliferation J Biol Chem 283 2008 6530 6545
    • (2008) J Biol Chem , vol.283 , pp. 6530-6545
    • Meran, S.1    Thomas, D.W.2    Stephens, P.3
  • 38
    • 56149111255 scopus 로고    scopus 로고
    • Cytoplasmic signalling by the c-Abl tyrosine kinase in normal and cancer cells
    • A. Sirvent, C. Benistant, and S. Roche Cytoplasmic signalling by the c-Abl tyrosine kinase in normal and cancer cells Biol Cell 100 2008 617 631
    • (2008) Biol Cell , vol.100 , pp. 617-631
    • Sirvent, A.1    Benistant, C.2    Roche, S.3
  • 40
    • 60149093582 scopus 로고    scopus 로고
    • Non-classical p38 map kinase functions: Cell cycle checkpoints and survival
    • T.M. Thornton, and M. Rincon Non-classical p38 map kinase functions: cell cycle checkpoints and survival Int J Biol Sci 5 2009 44 51
    • (2009) Int J Biol Sci , vol.5 , pp. 44-51
    • Thornton, T.M.1    Rincon, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.