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Volumn 82, Issue 4-5, 2011, Pages 261-271

Diabetes, growth hormone-insulin-like growth factor pathways and association to benign prostatic hyperplasia

Author keywords

Benign prostatic hyperplasia; C Jun; Diabetes; Hyperinsulinaemia; Insulin like growth factor; Insulin like growth factor binding protein

Indexed keywords

ANDROSTANEDIOL; GONADORELIN ANTAGONIST; GROWTH HORMONE; INSULIN; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROSTATE SPECIFIC ANTIGEN; PROTEIN C JUN; SEX HORMONE BINDING GLOBULIN; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; SOMATOMEDIN RECEPTOR; TESTOSTERONE;

EID: 80052967098     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2011.04.004     Document Type: Review
Times cited : (49)

References (147)
  • 1
    • 55249100997 scopus 로고    scopus 로고
    • Role of IGF-I in glucose regulation and cardiovascular disease
    • Abbas A., Grant P.J., Kearney M.T. Role of IGF-I in glucose regulation and cardiovascular disease. Expert. Rev. Cardiovasc. Ther. 2008, 6:1135-1149.
    • (2008) Expert. Rev. Cardiovasc. Ther. , vol.6 , pp. 1135-1149
    • Abbas, A.1    Grant, P.J.2    Kearney, M.T.3
  • 2
    • 0021687738 scopus 로고
    • Effect of diabetes and its control on insulin-like growth factors in the young subject with type I diabetes
    • Amiel S.A., Sherwin R.S., Hintz R.L., Gertner J.M., Press C.M., Tamborlane W.V. Effect of diabetes and its control on insulin-like growth factors in the young subject with type I diabetes. Diabetes 1984, 33:1175-1179.
    • (1984) Diabetes , vol.33 , pp. 1175-1179
    • Amiel, S.A.1    Sherwin, R.S.2    Hintz, R.L.3    Gertner, J.M.4    Press, C.M.5    Tamborlane, W.V.6
  • 3
    • 0036709021 scopus 로고    scopus 로고
    • Function of AP-1 target genes in mesenchymal-epithelial cross-talk in skin
    • Angel P., Szabowski A. Function of AP-1 target genes in mesenchymal-epithelial cross-talk in skin. Biochem. Pharmacol. 2002, 64:949-956.
    • (2002) Biochem. Pharmacol. , vol.64 , pp. 949-956
    • Angel, P.1    Szabowski, A.2
  • 4
    • 0035971572 scopus 로고    scopus 로고
    • Function and regulation of AP-1 subunits in skin physiology and pathology
    • Angel P., Szabowski A., Schorpp-Kistner M. Function and regulation of AP-1 subunits in skin physiology and pathology. Oncogene 2001, 20:2413-2423.
    • (2001) Oncogene , vol.20 , pp. 2413-2423
    • Angel, P.1    Szabowski, A.2    Schorpp-Kistner, M.3
  • 5
    • 0031757612 scopus 로고    scopus 로고
    • Characterisation of inflammatory cells in benign prostatic hyperplasia
    • Anim J.T., Udo C., John B. Characterisation of inflammatory cells in benign prostatic hyperplasia. Acta. Histochem. 1998, 100:439-449.
    • (1998) Acta. Histochem. , vol.100 , pp. 439-449
    • Anim, J.T.1    Udo, C.2    John, B.3
  • 7
    • 0027423419 scopus 로고
    • Role of insulin-like growth factors in embryonic and postnatal growth
    • Baker J., Liu J.P., Robertson E.J., Efstratiadis A. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 1993, 75:73-82.
    • (1993) Cell , vol.75 , pp. 73-82
    • Baker, J.1    Liu, J.P.2    Robertson, E.J.3    Efstratiadis, A.4
  • 8
    • 0028347171 scopus 로고
    • Insulin-like growth factor-I (IGF-I) and its binding protein IGFBP-4 in human prostatic hyperplastic tissue: Gene expression and its cellular localization
    • Barni T., Vannelli B.G., Sadri R., Pupilli C., Ghiandi P., Rizzo M., Selli C., Serio M., Fiorelli G. Insulin-like growth factor-I (IGF-I) and its binding protein IGFBP-4 in human prostatic hyperplastic tissue: Gene expression and its cellular localization. J. Clin. Endocrinol. Metab. 1994, 78:778-783.
    • (1994) J. Clin. Endocrinol. Metab. , vol.78 , pp. 778-783
    • Barni, T.1    Vannelli, B.G.2    Sadri, R.3    Pupilli, C.4    Ghiandi, P.5    Rizzo, M.6    Selli, C.7    Serio, M.8    Fiorelli, G.9
  • 9
    • 0033920612 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-binding proteins: Interactions with IGFs and intrinsic bioactivities
    • Baxter R.C. Insulin-like growth factor (IGF)-binding proteins: Interactions with IGFs and intrinsic bioactivities. Am. J. Physiol. Endocrinol. Metab. 2000, 278:E967-976.
    • (2000) Am. J. Physiol. Endocrinol. Metab. , vol.278
    • Baxter, R.C.1
  • 11
    • 0027359618 scopus 로고
    • Benign prostatic hyperplasia and normal prostate aging: Differences in types I and II 5 alpha-reductase and steroid hormone receptor messenger ribonucleic acid (mRNA) levels, but not in insulin-like growth factor mRNA levels
    • Bonnet P., Reiter E., Bruyninx M., Sente B., Dombrowicz D., de Leval J., Closset J., Hennen G. Benign prostatic hyperplasia and normal prostate aging: Differences in types I and II 5 alpha-reductase and steroid hormone receptor messenger ribonucleic acid (mRNA) levels, but not in insulin-like growth factor mRNA levels. J. Clin. Endocrinol. Metab. 1993, 77:1203-1208.
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , pp. 1203-1208
    • Bonnet, P.1    Reiter, E.2    Bruyninx, M.3    Sente, B.4    Dombrowicz, D.5    de Leval, J.6    Closset, J.7    Hennen, G.8
  • 12
    • 0030062101 scopus 로고    scopus 로고
    • Secretion of insulin-like growth factors and their binding proteins by human normal and hyperplastic prostatic cells in primary culture
    • Boudon C., Rodier G., Lechevallier E., Mottet N., Barenton B., Sultan C Secretion of insulin-like growth factors and their binding proteins by human normal and hyperplastic prostatic cells in primary culture. J. Clin. Endocrinol. Metab. 1996, 81:612-617.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 612-617
    • Boudon, C.1    Rodier, G.2    Lechevallier, E.3    Mottet, N.4    Barenton, B.5    Sultan, C.6
  • 13
    • 0028223994 scopus 로고
    • Comparison of the metabolic effects of recombinant human insulin-like growth factor-I and insulin. Dose-response relationships in healthy young and middle-aged adults
    • Boulware S.D., Tamborlane W.V., Rennert N.J., Gesundheit N., Sherwin R.S Comparison of the metabolic effects of recombinant human insulin-like growth factor-I and insulin. Dose-response relationships in healthy young and middle-aged adults. J. Clin. Invest. 1994, 93:1131-1139.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1131-1139
    • Boulware, S.D.1    Tamborlane, W.V.2    Rennert, N.J.3    Gesundheit, N.4    Sherwin, R.S.5
  • 14
    • 0013875130 scopus 로고
    • Hypertension, diabetes mellitus, and blood groups in benign prostatic hypertrophy
    • Bourke J.B., Griffin J.P. Hypertension, diabetes mellitus, and blood groups in benign prostatic hypertrophy. Br. J. Urol. 1966, 38:18-23.
    • (1966) Br. J. Urol. , vol.38 , pp. 18-23
    • Bourke, J.B.1    Griffin, J.P.2
  • 15
    • 33746660331 scopus 로고    scopus 로고
    • P38 MAPK in development and cancer
    • Bradham C., McClay D.R. p38 MAPK in development and cancer. Cell Cycle 2006, 5:824-828.
    • (2006) Cell Cycle , vol.5 , pp. 824-828
    • Bradham, C.1    McClay, D.R.2
  • 19
    • 0035043918 scopus 로고    scopus 로고
    • Control of growth by the somatropic axis: Growth hormone and the insulin-like growth factors have related and independent roles
    • Butler A.A., Le Roith D. Control of growth by the somatropic axis: Growth hormone and the insulin-like growth factors have related and independent roles. Annu. Rev. Physiol. 2001, 63:141-164.
    • (2001) Annu. Rev. Physiol. , vol.63 , pp. 141-164
    • Butler, A.A.1    Le Roith, D.2
  • 20
    • 0022631504 scopus 로고
    • Characterization of insulin receptors in isolated epithelial cells of rat ventral prostate: Effect of fasting
    • Carmena M.J., Fernandez-Moreno M.D., Prieto J.C. Characterization of insulin receptors in isolated epithelial cells of rat ventral prostate: Effect of fasting. Cell. Biochem. Funct. 1986, 4:19-24.
    • (1986) Cell. Biochem. Funct. , vol.4 , pp. 19-24
    • Carmena, M.J.1    Fernandez-Moreno, M.D.2    Prieto, J.C.3
  • 21
    • 0032417035 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor-I (rhIGF-I) therapy in adults with type 1 diabetes mellitus: Effects on IGFs, IGF-binding proteins, glucose levels and insulin treatment
    • Carroll P.V., Umpleby M., Alexander E.L., Egel V.A., Callison K.V., Sonksen P.H., Russell-Jones D.L. Recombinant human insulin-like growth factor-I (rhIGF-I) therapy in adults with type 1 diabetes mellitus: Effects on IGFs, IGF-binding proteins, glucose levels and insulin treatment. Clin. Endocrinol. (Oxf) 1998, 49:739-746.
    • (1998) Clin. Endocrinol. (Oxf) , vol.49 , pp. 739-746
    • Carroll, P.V.1    Umpleby, M.2    Alexander, E.L.3    Egel, V.A.4    Callison, K.V.5    Sonksen, P.H.6    Russell-Jones, D.L.7
  • 22
    • 0028811130 scopus 로고
    • The effects of repeated daily recombinant human insulin-like growth factor I administration in adolescents with type 1 diabetes
    • Cheetham T.D., Holly J.M., Clayton K., Cwyfan-Hughes S., Dunger D.B. The effects of repeated daily recombinant human insulin-like growth factor I administration in adolescents with type 1 diabetes. Diabet. Med. 1995, 12:885-892.
    • (1995) Diabet. Med. , vol.12 , pp. 885-892
    • Cheetham, T.D.1    Holly, J.M.2    Clayton, K.3    Cwyfan-Hughes, S.4    Dunger, D.B.5
  • 24
    • 11244352382 scopus 로고    scopus 로고
    • Interaction between insulin-like growth factor-I receptor and alphaVbeta3 integrin linked signaling pathways: Cellular responses to changes in multiple signaling inputs
    • Clemmons D.R., Maile L.A. Interaction between insulin-like growth factor-I receptor and alphaVbeta3 integrin linked signaling pathways: Cellular responses to changes in multiple signaling inputs. Mol. Endocrinol. 2005, 19:1-11.
    • (2005) Mol. Endocrinol. , vol.19 , pp. 1-11
    • Clemmons, D.R.1    Maile, L.A.2
  • 25
    • 0027944342 scopus 로고
    • Insulin-like growth factor axis abnormalities in prostatic stromal cells from patients with benign prostatic hyperplasia
    • Cohen P., Peehl D.M., Baker B., Liu F., Hintz R.L., Rosenfeld R.G. Insulin-like growth factor axis abnormalities in prostatic stromal cells from patients with benign prostatic hyperplasia. J. Clin. Endocrinol. Metab. 1994, 79:1410-1415.
    • (1994) J. Clin. Endocrinol. Metab. , vol.79 , pp. 1410-1415
    • Cohen, P.1    Peehl, D.M.2    Baker, B.3    Liu, F.4    Hintz, R.L.5    Rosenfeld, R.G.6
  • 26
    • 0026049726 scopus 로고
    • Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins in primary cultures of prostate epithelial cells
    • Cohen P., Peehl D.M., Lamson G., Rosenfeld R.G. Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins in primary cultures of prostate epithelial cells. J. Clin. Endocrinol. Metab. 1991, 73:401-407.
    • (1991) J. Clin. Endocrinol. Metab. , vol.73 , pp. 401-407
    • Cohen, P.1    Peehl, D.M.2    Lamson, G.3    Rosenfeld, R.G.4
  • 27
    • 0033305345 scopus 로고    scopus 로고
    • Effect of growth hormone (GH) and insulin-like growth factor I on prostate diseases: An ultrasonographic and endocrine study in acromegaly, GH deficiency, and healthy subjects
    • Colao A., Marzullo P., Spiezia S., Ferone D., Giaccio A., Cerbone G., Pivonello R., Di Somma C., Lombardi G. Effect of growth hormone (GH) and insulin-like growth factor I on prostate diseases: An ultrasonographic and endocrine study in acromegaly, GH deficiency, and healthy subjects. J. Clin. Endocrinol. Metab. 1999, 84:1986-1991.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 1986-1991
    • Colao, A.1    Marzullo, P.2    Spiezia, S.3    Ferone, D.4    Giaccio, A.5    Cerbone, G.6    Pivonello, R.7    Di Somma, C.8    Lombardi, G.9
  • 28
    • 0033941124 scopus 로고    scopus 로고
    • Effect of GH and/or testosterone deficiency on the prostate: An ultrasonographic and endocrine study in GH-deficient adult patients
    • Colao A., Spiezia S., Di Somma C., Marzullo P., Cerbone G., Pivonello R., Faggiano A., Lombardi G. Effect of GH and/or testosterone deficiency on the prostate: An ultrasonographic and endocrine study in GH-deficient adult patients. Eur. J. Endocrinol. 2000, 143:61-69.
    • (2000) Eur. J. Endocrinol. , vol.143 , pp. 61-69
    • Colao, A.1    Spiezia, S.2    Di Somma, C.3    Marzullo, P.4    Cerbone, G.5    Pivonello, R.6    Faggiano, A.7    Lombardi, G.8
  • 31
    • 0016967667 scopus 로고
    • Stromal induction and specification of morphogenesis and cytodifferentiation of the epithelia of the Mullerian ducts and urogenital sinus during development of the uterus and vagina in mice
    • Cunha G.R. Stromal induction and specification of morphogenesis and cytodifferentiation of the epithelia of the Mullerian ducts and urogenital sinus during development of the uterus and vagina in mice. J. Exp. Zool. 1976, 196:361-370.
    • (1976) J. Exp. Zool. , vol.196 , pp. 361-370
    • Cunha, G.R.1
  • 32
    • 0019799945 scopus 로고
    • Stromal-epithelial interactions--I. Induction of prostatic phenotype in urothelium of testicular feminized (Tfm/y) mice
    • Cunha G.R., Chung L.W. Stromal-epithelial interactions--I. Induction of prostatic phenotype in urothelium of testicular feminized (Tfm/y) mice. J. Steroid Biochem. 1981, 14:1317-1324.
    • (1981) J. Steroid Biochem. , vol.14 , pp. 1317-1324
    • Cunha, G.R.1    Chung, L.W.2
  • 33
    • 0036074655 scopus 로고    scopus 로고
    • Body size and serum levels of insulin and leptin in relation to the risk of benign prostatic hyperplasia
    • Dahle S.E., Chokkalingam A.P., Gao Y.T., Deng J., Stanczyk F.Z., Hsing A.W. Body size and serum levels of insulin and leptin in relation to the risk of benign prostatic hyperplasia. J. Urol 2002, 168:599-604.
    • (2002) J. Urol , vol.168 , pp. 599-604
    • Dahle, S.E.1    Chokkalingam, A.P.2    Gao, Y.T.3    Deng, J.4    Stanczyk, F.Z.5    Hsing, A.W.6
  • 34
    • 0026021161 scopus 로고
    • Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease
    • DeFronzo R.A., Ferrannini E. Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 1991, 14:173-194.
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • DeFronzo, R.A.1    Ferrannini, E.2
  • 35
    • 0030839835 scopus 로고    scopus 로고
    • Decreased expression of Wilms' tumor gene WT-1 and elevated expression of insulin growth factor-II (IGF-II) and type 1 IGF receptor genes in prostatic stromal cells from patients with benign prostatic hyperplasia
    • Dong G., Rajah R., Vu T., Hoffman A.R., Rosenfeld R.G., Roberts C.T., Peehl D.M., Cohen P. Decreased expression of Wilms' tumor gene WT-1 and elevated expression of insulin growth factor-II (IGF-II) and type 1 IGF receptor genes in prostatic stromal cells from patients with benign prostatic hyperplasia. J. Clin. Endocrinol. Metab. 1997, 82:2198-2203.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 2198-2203
    • Dong, G.1    Rajah, R.2    Vu, T.3    Hoffman, A.R.4    Rosenfeld, R.G.5    Roberts, C.T.6    Peehl, D.M.7    Cohen, P.8
  • 36
    • 0242691046 scopus 로고    scopus 로고
    • AP-1: A double-edged sword in tumorigenesis
    • Eferl R., Wagner E.F. AP-1: A double-edged sword in tumorigenesis. Nat. Rev. Cancer 2003, 3:859-868.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 859-868
    • Eferl, R.1    Wagner, E.F.2
  • 38
  • 39
    • 0030453978 scopus 로고    scopus 로고
    • Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects
    • Federici M., Zucaro L., Porzio O., Massoud R., Borboni P., Lauro D., Sesti G. Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects. J. Clin. Invest. 1996, 98:2887-2893.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2887-2893
    • Federici, M.1    Zucaro, L.2    Porzio, O.3    Massoud, R.4    Borboni, P.5    Lauro, D.6    Sesti, G.7
  • 40
    • 0025825535 scopus 로고
    • Insulin-like growth factor-I receptors in human hyperplastic prostate tissue: Characterization, tissue localization, and their modulation by chronic treatment with a gonadotropin-releasing hormone analog
    • Fiorelli G., De Bellis A., Longo A., Giannini S., Natali A., Costantini A., Vannelli G.B., Serio M. Insulin-like growth factor-I receptors in human hyperplastic prostate tissue: Characterization, tissue localization, and their modulation by chronic treatment with a gonadotropin-releasing hormone analog. J. Clin. Endocrinol. Metab. 1991, 72:740-746.
    • (1991) J. Clin. Endocrinol. Metab. , vol.72 , pp. 740-746
    • Fiorelli, G.1    De Bellis, A.2    Longo, A.3    Giannini, S.4    Natali, A.5    Costantini, A.6    Vannelli, G.B.7    Serio, M.8
  • 41
    • 0028807373 scopus 로고
    • Insulin and insulin-like growth factor-I enhance human skeletal muscle protein anabolism during hyperaminoacidemia by different mechanisms
    • Fryburg D.A., Jahn L.A., Hill S.A., Oliveras D.M., Barrett E.J. Insulin and insulin-like growth factor-I enhance human skeletal muscle protein anabolism during hyperaminoacidemia by different mechanisms. J. Clin. Invest. 1995, 96:1722-1729.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1722-1729
    • Fryburg, D.A.1    Jahn, L.A.2    Hill, S.A.3    Oliveras, D.M.4    Barrett, E.J.5
  • 42
    • 73449114573 scopus 로고    scopus 로고
    • Exercise and the growth hormone-insulin-like growth factor axis
    • Frystyk J. Exercise and the growth hormone-insulin-like growth factor axis. Med. Sci. Sports Exerc. 2010, 42:58-66.
    • (2010) Med. Sci. Sports Exerc. , vol.42 , pp. 58-66
    • Frystyk, J.1
  • 43
    • 0030921226 scopus 로고    scopus 로고
    • The effect of oral glucose on serum free insulin-like growth factor-I and -II in health adults
    • Frystyk J., Grofte T., Skjaerbaek C., Orskov H. The effect of oral glucose on serum free insulin-like growth factor-I and -II in health adults. J. Clin. Endocrinol. Metab. 1997, 82:3124-3127.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 3124-3127
    • Frystyk, J.1    Grofte, T.2    Skjaerbaek, C.3    Orskov, H.4
  • 45
    • 0030059487 scopus 로고    scopus 로고
    • Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM)
    • Gibson J.M., Westwood M., Young R.J., White A. Reduced insulin-like growth factor binding protein-1 (IGFBP-1) levels correlate with increased cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM). J. Clin. Endocrinol. Metab. 1996, 81:860-863.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 860-863
    • Gibson, J.M.1    Westwood, M.2    Young, R.J.3    White, A.4
  • 46
    • 0346725867 scopus 로고    scopus 로고
    • Nutrition, insulin, insulin-like growth factors and cancer
    • Giovannucci E. Nutrition, insulin, insulin-like growth factors and cancer. Horm. Metab. Res. 2003, 35:694-704.
    • (2003) Horm. Metab. Res. , vol.35 , pp. 694-704
    • Giovannucci, E.1
  • 47
    • 0031773251 scopus 로고    scopus 로고
    • The insulin-like growth factor type I receptor stimulates growth and suppresses apoptosis in prostatic stromal cells
    • Grant E.S., Ross M.B., Ballard S., Naylor A., Habib F.K. The insulin-like growth factor type I receptor stimulates growth and suppresses apoptosis in prostatic stromal cells. J. Clin. Endocrinol. Metab. 1998, 83:3252-3257.
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 3252-3257
    • Grant, E.S.1    Ross, M.B.2    Ballard, S.3    Naylor, A.4    Habib, F.K.5
  • 48
    • 0023276184 scopus 로고
    • Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults
    • Guler H.P., Zapf J., Froesch E.R. Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults. N. Engl. J. Med. 1987, 317:137-140.
    • (1987) N. Engl. J. Med. , vol.317 , pp. 137-140
    • Guler, H.P.1    Zapf, J.2    Froesch, E.R.3
  • 49
    • 33845308799 scopus 로고    scopus 로고
    • Anthropometric and metabolic factors and risk of benign prostatic hyperplasia: A prospective cohort study of Air Force veterans
    • Gupta A., Gupta S., Pavuk M., Roehrborn C.G. Anthropometric and metabolic factors and risk of benign prostatic hyperplasia: A prospective cohort study of Air Force veterans. Urology 2006, 68:1198-1205.
    • (2006) Urology , vol.68 , pp. 1198-1205
    • Gupta, A.1    Gupta, S.2    Pavuk, M.3    Roehrborn, C.G.4
  • 50
    • 0141506880 scopus 로고    scopus 로고
    • Epidemic obesity and the metabolic syndrome
    • Haffner S., Taegtmeyer H. Epidemic obesity and the metabolic syndrome. Circulation 2003, 108:1541-1545.
    • (2003) Circulation , vol.108 , pp. 1541-1545
    • Haffner, S.1    Taegtmeyer, H.2
  • 51
    • 0033942502 scopus 로고    scopus 로고
    • Sex hormones, obesity, fat distribution, type 2 diabetes and insulin resistance: Epidemiological and clinical correlation
    • Haffner S.M. Sex hormones, obesity, fat distribution, type 2 diabetes and insulin resistance: Epidemiological and clinical correlation. Int. J. Obes. Relat. Metab. Disord. 2000, 24(Suppl 2):S56-58.
    • (2000) Int. J. Obes. Relat. Metab. Disord. , vol.24 , Issue.SUPPL 2
    • Haffner, S.M.1
  • 52
    • 0024778424 scopus 로고
    • Urodynamics in benign prostatic hyperplasia: A survey
    • Hald T. Urodynamics in benign prostatic hyperplasia: A survey. Prostate Suppl. 1989, 2:69-77.
    • (1989) Prostate Suppl. , vol.2 , pp. 69-77
    • Hald, T.1
  • 54
    • 0345085490 scopus 로고    scopus 로고
    • Clinical, anthropometric, metabolic and insulin profile of men with fast annual growth rates of benign prostatic hyperplasia
    • Hammarsten J., Hogstedt B. Clinical, anthropometric, metabolic and insulin profile of men with fast annual growth rates of benign prostatic hyperplasia. Blood Press. 1999, 8:29-36.
    • (1999) Blood Press. , vol.8 , pp. 29-36
    • Hammarsten, J.1    Hogstedt, B.2
  • 55
    • 0035108041 scopus 로고    scopus 로고
    • Hyperinsulinaemia as a risk factor for developing benign prostatic hyperplasia
    • Hammarsten J., Hogstedt B. Hyperinsulinaemia as a risk factor for developing benign prostatic hyperplasia. Eur. Urol. 2001, 39:151-158.
    • (2001) Eur. Urol. , vol.39 , pp. 151-158
    • Hammarsten, J.1    Hogstedt, B.2
  • 56
    • 0001154983 scopus 로고    scopus 로고
    • Components of the metabolic syndrome-risk factors for the development of benign prostatic hyperplasia
    • Hammarsten J., Hogstedt B., Holthuis N., Mellstrom D. Components of the metabolic syndrome-risk factors for the development of benign prostatic hyperplasia. Prostate Cancer Prostatic Dis. 1998, 1:157-162.
    • (1998) Prostate Cancer Prostatic Dis. , vol.1 , pp. 157-162
    • Hammarsten, J.1    Hogstedt, B.2    Holthuis, N.3    Mellstrom, D.4
  • 57
    • 0014736508 scopus 로고
    • Diurnal patterns of blood glucose, serum free fatty acids, insulin, glucagon and growth hormone in normals and juvenile diabetics
    • Hansen A.P., Johansen K. Diurnal patterns of blood glucose, serum free fatty acids, insulin, glucagon and growth hormone in normals and juvenile diabetics. Diabetologia 1970, 6:27-33.
    • (1970) Diabetologia , vol.6 , pp. 27-33
    • Hansen, A.P.1    Johansen, K.2
  • 58
    • 0033913093 scopus 로고    scopus 로고
    • Synthesis and regulation of sex hormone-binding globulin in obesity
    • Hautanen A. Synthesis and regulation of sex hormone-binding globulin in obesity. Int. J. Obes. Relat. Metab. Disord. 2000, 24(Suppl 2):S64-70.
    • (2000) Int. J. Obes. Relat. Metab. Disord. , vol.24 , Issue.SUPPL 2
    • Hautanen, A.1
  • 60
    • 33847199023 scopus 로고    scopus 로고
    • Medical therapy for benign prostatic hyperplasia-present and future impact
    • Issa M.M., Regan T.S. Medical therapy for benign prostatic hyperplasia-present and future impact. Am. J. Manag. Care 2007, 13(Suppl 1):S4-S9.
    • (2007) Am. J. Manag. Care , vol.13 , Issue.SUPPL 1
    • Issa, M.M.1    Regan, T.S.2
  • 61
    • 0031719744 scopus 로고    scopus 로고
    • Serum free and total insulin-like growth factor-I, insulin-like growth factor binding protein-1 and insulin-like growth factor binding protein-3 Levels in healthy elderly individuals. Relation to self-reported quality of health and disability
    • Janssen J.A., Stolk R.P., Pols H.A., Grobbee D.E., Lamberts S.W Serum free and total insulin-like growth factor-I, insulin-like growth factor binding protein-1 and insulin-like growth factor binding protein-3 Levels in healthy elderly individuals. Relation to self-reported quality of health and disability. Gerontology 1998, 44:277-280.
    • (1998) Gerontology , vol.44 , pp. 277-280
    • Janssen, J.A.1    Stolk, R.P.2    Pols, H.A.3    Grobbee, D.E.4    Lamberts, S.W.5
  • 62
    • 73949145707 scopus 로고    scopus 로고
    • IL-1 induces IGF-dependent epithelial proliferation in prostate development and reactive hyperplasia
    • Jerde, T.J., Bushman, W., 2009 IL-1 induces IGF-dependent epithelial proliferation in prostate development and reactive hyperplasia. Sci. Signal. 2:ra49.
    • (2009) Sci. Signal. , vol.2
    • Jerde, T.J.1    Bushman, W.2
  • 63
    • 0028958031 scopus 로고
    • Insulin-like growth factors and their binding proteins: Biological actions
    • Jones J.I., Clemmons D.R. Insulin-like growth factors and their binding proteins: Biological actions. Endocr. Rev. 1995, 16:3-34.
    • (1995) Endocr. Rev. , vol.16 , pp. 3-34
    • Jones, J.I.1    Clemmons, D.R.2
  • 64
    • 0036072361 scopus 로고    scopus 로고
    • Free and total insulin-like growth factor (IGF)-I levels decline during fasting: Relationships with insulin and IGF-binding protein-1
    • Katz L.E., DeLeon D.D., Zhao H., Jawad A.F. Free and total insulin-like growth factor (IGF)-I levels decline during fasting: Relationships with insulin and IGF-binding protein-1. J. Clin. Endocrinol. Metab. 2002, 87:2978-2983.
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 2978-2983
    • Katz, L.E.1    DeLeon, D.D.2    Zhao, H.3    Jawad, A.F.4
  • 66
    • 33847020869 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-I controls prostate fibromuscular development: IGF-I inhibition prevents both fibromuscular and glandular development in eugonadal mice
    • Kleinberg D.L., Ruan W., Yee D., Kovacs K.T., Vidal S. Insulin-like growth factor (IGF)-I controls prostate fibromuscular development: IGF-I inhibition prevents both fibromuscular and glandular development in eugonadal mice. Endocrinology 2007, 148:1080-1088.
    • (2007) Endocrinology , vol.148 , pp. 1080-1088
    • Kleinberg, D.L.1    Ruan, W.2    Yee, D.3    Kovacs, K.T.4    Vidal, S.5
  • 67
    • 33947172629 scopus 로고    scopus 로고
    • Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics
    • Krag M.B., Gormsen L.C., Guo Z., Christiansen J.S., Jensen M.D., Nielsen S., Jorgensen J.O. Growth hormone-induced insulin resistance is associated with increased intramyocellular triglyceride content but unaltered VLDL-triglyceride kinetics. Am. J. Physiol. Endocrinol. Metab. 2007, 292:E920-927.
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.292
    • Krag, M.B.1    Gormsen, L.C.2    Guo, Z.3    Christiansen, J.S.4    Jensen, M.D.5    Nielsen, S.6    Jorgensen, J.O.7
  • 68
    • 0027361099 scopus 로고
    • Comparison of the effects of recombinant human insulin-like growth factor-I and insulin on glucose and leucine kinetics in humans
    • Laager R., Ninnis R., Keller U Comparison of the effects of recombinant human insulin-like growth factor-I and insulin on glucose and leucine kinetics in humans. J. Clin. Invest. 1993, 92:1903-1909.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1903-1909
    • Laager, R.1    Ninnis, R.2    Keller, U.3
  • 69
    • 0022856921 scopus 로고
    • Diet, obesity and hypertension: An hypothesis involving insulin, the sympathetic nervous system, and adaptive thermogenesis
    • Landsberg L. Diet, obesity and hypertension: An hypothesis involving insulin, the sympathetic nervous system, and adaptive thermogenesis. Q. J. Med. 1986, 61:1081-1090.
    • (1986) Q. J. Med. , vol.61 , pp. 1081-1090
    • Landsberg, L.1
  • 70
    • 0041419377 scopus 로고    scopus 로고
    • Acute in vivo elevation of insulin-like growth factor (IGF) binding protein-1 decreases plasma free IGF-I and muscle protein synthesis
    • Lang C.H., Vary T.C., Frost R.A. Acute in vivo elevation of insulin-like growth factor (IGF) binding protein-1 decreases plasma free IGF-I and muscle protein synthesis. Endocrinology 2003, 144:3922-3933.
    • (2003) Endocrinology , vol.144 , pp. 3922-3933
    • Lang, C.H.1    Vary, T.C.2    Frost, R.A.3
  • 71
    • 27844461512 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in development and cancer: Role of phosphatidylinositol 3' kinase/AKT pathways
    • Larue L., Bellacosa A. Epithelial-mesenchymal transition in development and cancer: Role of phosphatidylinositol 3' kinase/AKT pathways. Oncogene 2005, 24:7443-7454.
    • (2005) Oncogene , vol.24 , pp. 7443-7454
    • Larue, L.1    Bellacosa, A.2
  • 73
    • 0028957113 scopus 로고
    • Molecular and cellular aspects of the insulin-like growth factor I receptor
    • LeRoith D., Werner H., Beitner-Johnson D., Roberts C.T. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr. Rev. 1995, 16:143-163.
    • (1995) Endocr. Rev. , vol.16 , pp. 143-163
    • LeRoith, D.1    Werner, H.2    Beitner-Johnson, D.3    Roberts, C.T.4
  • 74
    • 0026005865 scopus 로고
    • Insulin-like growth factor-binding protein-1 modulates blood glucose levels
    • Lewitt M.S., Denyer G.S., Cooney G.J., Baxter R.C. Insulin-like growth factor-binding protein-1 modulates blood glucose levels. Endocrinology 1991, 129:2254-2256.
    • (1991) Endocrinology , vol.129 , pp. 2254-2256
    • Lewitt, M.S.1    Denyer, G.S.2    Cooney, G.J.3    Baxter, R.C.4
  • 75
  • 76
    • 35348861265 scopus 로고    scopus 로고
    • Stromally expressed c-Jun regulates proliferation of prostate epithelial cells
    • Li W., Wu C.L., Febbo P.G., Olumi A.F. Stromally expressed c-Jun regulates proliferation of prostate epithelial cells. Am. J. Pathol. 2007, 171:1189-1198.
    • (2007) Am. J. Pathol. , vol.171 , pp. 1189-1198
    • Li, W.1    Wu, C.L.2    Febbo, P.G.3    Olumi, A.F.4
  • 77
    • 0037093815 scopus 로고    scopus 로고
    • Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis
    • Luo J., Dunn T., Ewing C., Sauvageot J., Chen Y., Trent J., Isaacs W. Gene expression signature of benign prostatic hyperplasia revealed by cDNA microarray analysis. Prostate 2002, 51:189-200.
    • (2002) Prostate , vol.51 , pp. 189-200
    • Luo, J.1    Dunn, T.2    Ewing, C.3    Sauvageot, J.4    Chen, Y.5    Trent, J.6    Isaacs, W.7
  • 78
    • 27144526198 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in cell-cycle control
    • MacCorkle R.A., Tan T.H. Mitogen-activated protein kinases in cell-cycle control. Cell Biochem. Biophys. 2005, 43:451-461.
    • (2005) Cell Biochem. Biophys. , vol.43 , pp. 451-461
    • MacCorkle, R.A.1    Tan, T.H.2
  • 79
    • 0035043176 scopus 로고    scopus 로고
    • Phenotypic manifestations of insulin-like growth factor-binding protein-3 overexpression in transgenic mice
    • Modric T., Silha J.V., Shi Z., Gui Y., Suwanichkul A., Durham S.K., Powell D.R., Murphy L.J. Phenotypic manifestations of insulin-like growth factor-binding protein-3 overexpression in transgenic mice. Endocrinology 2001, 142:1958-1967.
    • (2001) Endocrinology , vol.142 , pp. 1958-1967
    • Modric, T.1    Silha, J.V.2    Shi, Z.3    Gui, Y.4    Suwanichkul, A.5    Durham, S.K.6    Powell, D.R.7    Murphy, L.J.8
  • 80
    • 0036803018 scopus 로고    scopus 로고
    • IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms
    • Mohan S., Baylink D.J. IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms. J. Endocrinol. 2002, 175:19-31.
    • (2002) J. Endocrinol. , vol.175 , pp. 19-31
    • Mohan, S.1    Baylink, D.J.2
  • 81
    • 0024508821 scopus 로고
    • Effects of growth hormone on insulin sensitivity and forearm metabolism in normal man
    • Moller N., Butler P.C., Antsiferov M.A., Alberti K.G. Effects of growth hormone on insulin sensitivity and forearm metabolism in normal man. Diabetologia 1989, 32:105-110.
    • (1989) Diabetologia , vol.32 , pp. 105-110
    • Moller, N.1    Butler, P.C.2    Antsiferov, M.A.3    Alberti, K.G.4
  • 82
    • 65249171425 scopus 로고    scopus 로고
    • Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects
    • Moller N., Jorgensen J.O. Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects. Endocr. Rev. 2009, 30:152-177.
    • (2009) Endocr. Rev. , vol.30 , pp. 152-177
    • Moller, N.1    Jorgensen, J.O.2
  • 84
    • 17744369065 scopus 로고    scopus 로고
    • Regional ariations of insulin-like growth factor I (IGF-I), IGF-II, and receptor type I in benign prostatic hyperplasia tissue and their correlation with intraprostatic androgens
    • Monti S., Di Silverio F., Iraci R., Martini C., Lanzara S., Falasca P., Poggi M., Stigliano A., Sciarra F., Toscano V. Regional ariations of insulin-like growth factor I (IGF-I), IGF-II, and receptor type I in benign prostatic hyperplasia tissue and their correlation with intraprostatic androgens. J. Clin. Endocrinol. Metab. 2001, 86:1700-1706.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 1700-1706
    • Monti, S.1    Di Silverio, F.2    Iraci, R.3    Martini, C.4    Lanzara, S.5    Falasca, P.6    Poggi, M.7    Stigliano, A.8    Sciarra, F.9    Toscano, V.10
  • 85
    • 0032076228 scopus 로고    scopus 로고
    • Insulin-like growth factor-I and -II in human benign prostatic hyperplasia: Relationship with binding proteins 2 and 3 and androgens
    • Monti S., Di Silverio F., Lanzara S., Varasano P., Martini C., Tosti-Croce C., Sciarra F. Insulin-like growth factor-I and -II in human benign prostatic hyperplasia: Relationship with binding proteins 2 and 3 and androgens. Steroids 1998, 63:362-366.
    • (1998) Steroids , vol.63 , pp. 362-366
    • Monti, S.1    Di Silverio, F.2    Lanzara, S.3    Varasano, P.4    Martini, C.5    Tosti-Croce, C.6    Sciarra, F.7
  • 86
    • 0027410534 scopus 로고
    • Nonuniform regional sympathetic nerve responses to hyperinsulinemia in rats
    • Morgan D.A., Balon T.W., Ginsberg B.H., Mark A.L. Nonuniform regional sympathetic nerve responses to hyperinsulinemia in rats. Am. J. Physiol. 1993, 264:R423-427.
    • (1993) Am. J. Physiol. , vol.264
    • Morgan, D.A.1    Balon, T.W.2    Ginsberg, B.H.3    Mark, A.L.4
  • 87
    • 0028300538 scopus 로고
    • Recombinant human insulin-like growth factor-I therapy improves glycemic control and insulin action in the type A syndrome of severe insulin resistance
    • Morrow L.A., O'Brien M.B., Moller D.E., Flier J.S., Moses A.C. Recombinant human insulin-like growth factor-I therapy improves glycemic control and insulin action in the type A syndrome of severe insulin resistance. J. Clin. Endocrinol. Metab 1994, 79:205-210.
    • (1994) J. Clin. Endocrinol. Metab , vol.79 , pp. 205-210
    • Morrow, L.A.1    O'Brien, M.B.2    Moller, D.E.3    Flier, J.S.4    Moses, A.C.5
  • 88
    • 0030032795 scopus 로고    scopus 로고
    • Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes
    • Moses A.C., Young S.C., Morrow L.A., O'Brien M., Clemmons D.R. Recombinant human insulin-like growth factor I increases insulin sensitivity and improves glycemic control in type II diabetes. Diabetes 1996, 45:91-100.
    • (1996) Diabetes , vol.45 , pp. 91-100
    • Moses, A.C.1    Young, S.C.2    Morrow, L.A.3    O'Brien, M.4    Clemmons, D.R.5
  • 89
    • 33746044904 scopus 로고    scopus 로고
    • Hyperinsulinemia and dyslipidemia in non-diabetic benign prostatic hyperplasia
    • Nandeesha H., Koner B.C., Dorairajan L.N., Sen S.K. Hyperinsulinemia and dyslipidemia in non-diabetic benign prostatic hyperplasia. Clin. Chim. Acta 2006, 370:89-93.
    • (2006) Clin. Chim. Acta , vol.370 , pp. 89-93
    • Nandeesha, H.1    Koner, B.C.2    Dorairajan, L.N.3    Sen, S.K.4
  • 90
    • 84926088060 scopus 로고    scopus 로고
    • Growth hormone-insulin-like growth factor-1 and inflammatory response to a single exercise bout in children and adolescents
    • Nemet D., Eliakim A. Growth hormone-insulin-like growth factor-1 and inflammatory response to a single exercise bout in children and adolescents. Med. Sport. Sci. 2010, 55:141-155.
    • (2010) Med. Sport. Sci. , vol.55 , pp. 141-155
    • Nemet, D.1    Eliakim, A.2
  • 91
    • 50949085355 scopus 로고    scopus 로고
    • Insulin-like growth factor-I, insulin-like growth factor binding protein-3 and risk of benign prostate hyperplasia in the prostate cancer prevention trial
    • Neuhouser M.L., Schenk J., Song Y.J., Tangen C.M., Goodman P.J., Pollak M., Penson D.F., Thompson I.M., Kristal A.R. Insulin-like growth factor-I, insulin-like growth factor binding protein-3 and risk of benign prostate hyperplasia in the prostate cancer prevention trial. Prostate 2008, 68:1477-1486.
    • (2008) Prostate , vol.68 , pp. 1477-1486
    • Neuhouser, M.L.1    Schenk, J.2    Song, Y.J.3    Tangen, C.M.4    Goodman, P.J.5    Pollak, M.6    Penson, D.F.7    Thompson, I.M.8    Kristal, A.R.9
  • 92
    • 0032715912 scopus 로고    scopus 로고
    • Asymptomatic inflammation and/or infection in benign prostatic hyperplasia
    • Nickel J.C., Downey J., Young I., Boag S. Asymptomatic inflammation and/or infection in benign prostatic hyperplasia. BJU Int. 1999, 84:976-981.
    • (1999) BJU Int. , vol.84 , pp. 976-981
    • Nickel, J.C.1    Downey, J.2    Young, I.3    Boag, S.4
  • 93
    • 0033251134 scopus 로고    scopus 로고
    • Bicalutamide (Casodex)-induced prostate regression involves increased expression of genes encoding insulin-like growth factor binding proteins
    • Nickerson T., Pollak M. Bicalutamide (Casodex)-induced prostate regression involves increased expression of genes encoding insulin-like growth factor binding proteins. Urology 1999, 54:1120-1125.
    • (1999) Urology , vol.54 , pp. 1120-1125
    • Nickerson, T.1    Pollak, M.2
  • 94
    • 0035491321 scopus 로고    scopus 로고
    • Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure
    • Nielsen S., Moller N., Christiansen J.S., Jorgensen J.O. Pharmacological antilipolysis restores insulin sensitivity during growth hormone exposure. Diabetes 2001, 50:2301-2308.
    • (2001) Diabetes , vol.50 , pp. 2301-2308
    • Nielsen, S.1    Moller, N.2    Christiansen, J.S.3    Jorgensen, J.O.4
  • 95
    • 0025780545 scopus 로고
    • Insulin-like growth factor receptors
    • Nissley P., Lopaczynski W. Insulin-like growth factor receptors. Growth Factors 1991, 5:29-43.
    • (1991) Growth Factors , vol.5 , pp. 29-43
    • Nissley, P.1    Lopaczynski, W.2
  • 96
    • 0030743444 scopus 로고    scopus 로고
    • Free insulin-like growth factor I (IGF-I) in healthy subjects: Relationship with IGF-binding proteins and insulin sensitivity
    • Nyomba B.L., Berard L., Murphy L.J. Free insulin-like growth factor I (IGF-I) in healthy subjects: Relationship with IGF-binding proteins and insulin sensitivity. J. Clin. Endocrinol. Metab. 1997, 82:2177-2181.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 2177-2181
    • Nyomba, B.L.1    Berard, L.2    Murphy, L.J.3
  • 97
    • 33644866505 scopus 로고    scopus 로고
    • The magnitude of early castration-induced primary tumour regression in prostate cancer does not predict clinical outcome
    • Ohlson N., Bergh A., Nygren K., Stattin P., Wikstrom P. The magnitude of early castration-induced primary tumour regression in prostate cancer does not predict clinical outcome. Eur. Urol. 2006, 49:675-683.
    • (2006) Eur. Urol. , vol.49 , pp. 675-683
    • Ohlson, N.1    Bergh, A.2    Nygren, K.3    Stattin, P.4    Wikstrom, P.5
  • 98
    • 33845760880 scopus 로고    scopus 로고
    • Castration-induced epithelial cell death in human prostate tissue is related to locally reduced IGF-I levels
    • Ohlson N., Bergh A., Stattin P., Wikstrom P. Castration-induced epithelial cell death in human prostate tissue is related to locally reduced IGF-I levels. Prostate 2007, 67:32-40.
    • (2007) Prostate , vol.67 , pp. 32-40
    • Ohlson, N.1    Bergh, A.2    Stattin, P.3    Wikstrom, P.4
  • 99
    • 33751414540 scopus 로고    scopus 로고
    • The correlation between metabolic syndrome and prostatic growth in patients with benign prostatic hyperplasia
    • discussion 204-196.
    • Ozden, C., Ozdal, O.L., Urgancioglu, G., Koyuncu, H., Gokkaya, S., Memis, A., 2007 The correlation between metabolic syndrome and prostatic growth in patients with benign prostatic hyperplasia. Eur. Urol. 51, 199-203; discussion 204-196.
    • (2007) , vol.51 , pp. 199-203
    • Ozden, C.1    Ozdal, O.L.2    Urgancioglu, G.3    Koyuncu, H.4    Gokkaya, S.5    Memis, A.6
  • 100
    • 0034958561 scopus 로고    scopus 로고
    • Molecular 'palpation' of BPH: A tale of MAPK signalling?
    • Papatsoris A.G., Papavassiliou A.G. Molecular 'palpation' of BPH: A tale of MAPK signalling?. Trends Mol. Med. 2001, 7:288-292.
    • (2001) Trends Mol. Med. , vol.7 , pp. 288-292
    • Papatsoris, A.G.1    Papavassiliou, A.G.2
  • 101
    • 37849030164 scopus 로고    scopus 로고
    • Lipids, lipoproteins and the risk of benign prostatic hyperplasia in community-dwelling men
    • Parsons J.K., Bergstrom J., Barrett-Connor E. Lipids, lipoproteins and the risk of benign prostatic hyperplasia in community-dwelling men. BJU Int. 2008, 101:313-318.
    • (2008) BJU Int. , vol.101 , pp. 313-318
    • Parsons, J.K.1    Bergstrom, J.2    Barrett-Connor, E.3
  • 103
    • 0029439502 scopus 로고
    • The insulin-like growth factor system in the prostate
    • Peehl D.M., Cohen P., Rosenfeld R.G. The insulin-like growth factor system in the prostate. World J. Urol. 1995, 13:306-311.
    • (1995) World J. Urol. , vol.13 , pp. 306-311
    • Peehl, D.M.1    Cohen, P.2    Rosenfeld, R.G.3
  • 104
    • 0030000740 scopus 로고    scopus 로고
    • The role of insulin-like growth factors in prostate biology
    • Peehl D.M., Cohen P., Rosenfeld R.G. The role of insulin-like growth factors in prostate biology. J. Androl. 1996, 17:2-4.
    • (1996) J. Androl. , vol.17 , pp. 2-4
    • Peehl, D.M.1    Cohen, P.2    Rosenfeld, R.G.3
  • 105
    • 0037227681 scopus 로고    scopus 로고
    • A novel view on the mechanisms of action of insulin and other insulin superfamily peptides: Involvement of adenylyl cyclase signaling system
    • Pertseva M.N., Shpakov A.O., Plesneva S.A., Kuznetsova L.A. A novel view on the mechanisms of action of insulin and other insulin superfamily peptides: Involvement of adenylyl cyclase signaling system. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 2003, 134:11-36.
    • (2003) Comp. Biochem. Physiol. B Biochem. Mol. Biol. , vol.134 , pp. 11-36
    • Pertseva, M.N.1    Shpakov, A.O.2    Plesneva, S.A.3    Kuznetsova, L.A.4
  • 107
    • 56749184290 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor signalling in neoplasia
    • Pollak M. Insulin and insulin-like growth factor signalling in neoplasia. Nat. Rev. Cancer 2008, 8:915-928.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 915-928
    • Pollak, M.1
  • 112
    • 77952784903 scopus 로고    scopus 로고
    • Treatment with recombinant human insulin-like growth factor (rhIGF)-I/rhIGF binding protein-3 complex improves metabolic control in subjects with severe insulin resistance
    • Regan F.M., Williams R.M., McDonald A., Umpleby A.M., Acerini C.L., O'Rahilly S., Hovorka R., Semple R.K., Dunger D.B. Treatment with recombinant human insulin-like growth factor (rhIGF)-I/rhIGF binding protein-3 complex improves metabolic control in subjects with severe insulin resistance. J. Clin. Endocrinol. Metab. 2010, 95:2113-2122.
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 2113-2122
    • Regan, F.M.1    Williams, R.M.2    McDonald, A.3    Umpleby, A.M.4    Acerini, C.L.5    O'Rahilly, S.6    Hovorka, R.7    Semple, R.K.8    Dunger, D.B.9
  • 113
    • 79960364308 scopus 로고    scopus 로고
    • Longitudinal association between IGFBP-1 levels and parameters of the metabolic syndrome in obese children before and after weight loss
    • Reinehr T., Kleber M., Toschke A.M., Woelfle J., Roth C.L. Longitudinal association between IGFBP-1 levels and parameters of the metabolic syndrome in obese children before and after weight loss. Int. J. Pediatr. Obes 2011.
    • (2011) Int. J. Pediatr. Obes
    • Reinehr, T.1    Kleber, M.2    Toschke, A.M.3    Woelfle, J.4    Roth, C.L.5
  • 115
    • 0038416674 scopus 로고    scopus 로고
    • Insulin-like growth factor I, insulin-like growth factor binding protein 3, and urologic measures of benign prostatic hyperplasia
    • Roberts R.O., Jacobson D.J., Girman C.J., Rhodes T., Klee G.G., Lieber M.M., Jacobsen S.J. Insulin-like growth factor I, insulin-like growth factor binding protein 3, and urologic measures of benign prostatic hyperplasia. Am. J. Epidemiol. 2003, 157:784-791.
    • (2003) Am. J. Epidemiol. , vol.157 , pp. 784-791
    • Roberts, R.O.1    Jacobson, D.J.2    Girman, C.J.3    Rhodes, T.4    Klee, G.G.5    Lieber, M.M.6    Jacobsen, S.J.7
  • 116
    • 73449091835 scopus 로고    scopus 로고
    • Mecasermin (recombinant human insulin-like growth factor I)
    • Rosenbloom A.L. Mecasermin (recombinant human insulin-like growth factor I). Adv. Ther. 2009, 26:40-54.
    • (2009) Adv. Ther. , vol.26 , pp. 40-54
    • Rosenbloom, A.L.1
  • 117
    • 0031449201 scopus 로고    scopus 로고
    • Endometrial transcripts of human insulin-like growth factors arise by differential promoter usage
    • Roy R.N., Cecutti A., Gerulath A.H., Steinberg W.M., Bhavnani B.R. Endometrial transcripts of human insulin-like growth factors arise by differential promoter usage. Mol. Cell. Endocrinol. 1997, 135:11-19.
    • (1997) Mol. Cell. Endocrinol. , vol.135 , pp. 11-19
    • Roy, R.N.1    Cecutti, A.2    Gerulath, A.H.3    Steinberg, W.M.4    Bhavnani, B.R.5
  • 118
    • 0033306843 scopus 로고    scopus 로고
    • Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development
    • Ruan W., Powell-Braxton L., Kopchick J.J., Kleinberg D.L. Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development. Endocrinology 1999, 140:1984-1989.
    • (1999) Endocrinology , vol.140 , pp. 1984-1989
    • Ruan, W.1    Powell-Braxton, L.2    Kopchick, J.J.3    Kleinberg, D.L.4
  • 120
    • 0026476091 scopus 로고
    • Intraperitoneal insulin is more potent than subcutaneous insulin at restoring hepatic insulin-like growth factor-I mRNA levels in the diabetic rat: A functional role for the portal vascular link
    • Russell-Jones D.L., Rattray M., Wilson V.J., Jones R.H., Sonksen P.H., Thomas C.R. Intraperitoneal insulin is more potent than subcutaneous insulin at restoring hepatic insulin-like growth factor-I mRNA levels in the diabetic rat: A functional role for the portal vascular link. J. Mol. Endocrinol. 1992, 9:257-263.
    • (1992) J. Mol. Endocrinol. , vol.9 , pp. 257-263
    • Russell-Jones, D.L.1    Rattray, M.2    Wilson, V.J.3    Jones, R.H.4    Sonksen, P.H.5    Thomas, C.R.6
  • 122
    • 4544238815 scopus 로고    scopus 로고
    • Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/IGF binding protein-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes
    • Saukkonen T., Amin R., Williams R.M., Fox C., Yuen K.C., White M.A., Umpleby A.M., Acerini C.L., Dunger D.B. Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/IGF binding protein-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes. J. Clin. Endocrinol. Metab. 2004, 89:4634-4641.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 4634-4641
    • Saukkonen, T.1    Amin, R.2    Williams, R.M.3    Fox, C.4    Yuen, K.C.5    White, M.A.6    Umpleby, A.M.7    Acerini, C.L.8    Dunger, D.B.9
  • 124
    • 0034604529 scopus 로고    scopus 로고
    • Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit
    • Schedlich L.J., Le Page S.L., Firth S.M., Briggs L.J., Jans D.A., Baxter R.C. Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit. J. Biol. Chem. 2000, 275:23462-23470.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23462-23470
    • Schedlich, L.J.1    Le Page, S.L.2    Firth, S.M.3    Briggs, L.J.4    Jans, D.A.5    Baxter, R.C.6
  • 125
    • 23244434632 scopus 로고    scopus 로고
    • Changes in insulin sensitivity induced by short-term growth hormone (GH) and insulin-like growth factor I (IGF-I) treatment in GH-deficient adults are not associated with changes in adiponectin levels
    • Schmid C., Bianda T., Zwimpfer C., Zapf J., Wiesli P. Changes in insulin sensitivity induced by short-term growth hormone (GH) and insulin-like growth factor I (IGF-I) treatment in GH-deficient adults are not associated with changes in adiponectin levels. Growth Horm. IGF Res. 2005, 15:300-303.
    • (2005) Growth Horm. IGF Res. , vol.15 , pp. 300-303
    • Schmid, C.1    Bianda, T.2    Zwimpfer, C.3    Zapf, J.4    Wiesli, P.5
  • 127
    • 0036518927 scopus 로고    scopus 로고
    • Study of the functional organization of a novel adenylate cyclase signaling mechanism of insulin action
    • Shpakov A.O., Plesneva S.A., Kuznetsova L.A., Pertseva M.N. Study of the functional organization of a novel adenylate cyclase signaling mechanism of insulin action. Biochemistry (Mosc) 2002, 67:335-342.
    • (2002) Biochemistry (Mosc) , vol.67 , pp. 335-342
    • Shpakov, A.O.1    Plesneva, S.A.2    Kuznetsova, L.A.3    Pertseva, M.N.4
  • 128
    • 14244270346 scopus 로고    scopus 로고
    • Overexpression of gly56/gly80/gly81-mutant insulin-like growth factor-binding protein-3 in transgenic mice
    • Silha J.V., Gui Y., Mishra S., Leckstrom A., Cohen P., Murphy L.J. Overexpression of gly56/gly80/gly81-mutant insulin-like growth factor-binding protein-3 in transgenic mice. Endocrinology 2005, 146:1523-1531.
    • (2005) Endocrinology , vol.146 , pp. 1523-1531
    • Silha, J.V.1    Gui, Y.2    Mishra, S.3    Leckstrom, A.4    Cohen, P.5    Murphy, L.J.6
  • 129
    • 0029053398 scopus 로고
    • Malignant breast epithelium selects for insulin-like growth factor II expression in breast stroma: Evidence for paracrine function
    • Singer C., Rasmussen A., Smith H.S., Lippman M.E., Lynch H.T., Cullen K.J. Malignant breast epithelium selects for insulin-like growth factor II expression in breast stroma: Evidence for paracrine function. Cancer Res. 1995, 55:2448-2454.
    • (1995) Cancer Res. , vol.55 , pp. 2448-2454
    • Singer, C.1    Rasmussen, A.2    Smith, H.S.3    Lippman, M.E.4    Lynch, H.T.5    Cullen, K.J.6
  • 131
    • 47049083139 scopus 로고    scopus 로고
    • IMMULITE 2000 age and sex-specific reference intervals for alpha fetoprotein, homocysteine, insulin, insulin-like growth factor-1, insulin-like growth factor binding protein-3, C-peptide, immunoglobulin E and intact parathyroid hormone
    • Soldin O.P., Dahlin J.R., Gresham E.G., King J., Soldin S.J. IMMULITE 2000 age and sex-specific reference intervals for alpha fetoprotein, homocysteine, insulin, insulin-like growth factor-1, insulin-like growth factor binding protein-3, C-peptide, immunoglobulin E and intact parathyroid hormone. Clin. Biochem. 2008, 41:937-942.
    • (2008) Clin. Biochem. , vol.41 , pp. 937-942
    • Soldin, O.P.1    Dahlin, J.R.2    Gresham, E.G.3    King, J.4    Soldin, S.J.5
  • 132
    • 17144395975 scopus 로고    scopus 로고
    • The activation of Akt/PKB signaling pathway and cell survival
    • Song G., Ouyang G., Bao S. The activation of Akt/PKB signaling pathway and cell survival. J. Cell. Mol. Med. 2005, 9:59-71.
    • (2005) J. Cell. Mol. Med. , vol.9 , pp. 59-71
    • Song, G.1    Ouyang, G.2    Bao, S.3
  • 135
    • 0030755561 scopus 로고    scopus 로고
    • Analysis of growth factor and receptor mRNA levels during development of the rat seminal vesicle and prostate
    • Thomson A.A., Foster B.A., Cunha G.R. Analysis of growth factor and receptor mRNA levels during development of the rat seminal vesicle and prostate. Development 1997, 124:2431-2439.
    • (1997) Development , vol.124 , pp. 2431-2439
    • Thomson, A.A.1    Foster, B.A.2    Cunha, G.R.3
  • 136
    • 0031005918 scopus 로고    scopus 로고
    • Systemic administration of insulin-like growth factor I (IGF-I) causes growth of the rat prostate
    • Torring N., Vinter-Jensen L., Pedersen S.B., Sorensen F.B., Flyvbjerg A., Nexo E. Systemic administration of insulin-like growth factor I (IGF-I) causes growth of the rat prostate. J. Urol. 1997, 158:222-227.
    • (1997) J. Urol. , vol.158 , pp. 222-227
    • Torring, N.1    Vinter-Jensen, L.2    Pedersen, S.B.3    Sorensen, F.B.4    Flyvbjerg, A.5    Nexo, E.6
  • 137
    • 0032851538 scopus 로고    scopus 로고
    • Androgens promote insulin-like growth factor-I and insulin-like growth factor-I receptor gene expression in the primate ovary
    • Vendola K., Zhou J., Wang J., Bondy C.A. Androgens promote insulin-like growth factor-I and insulin-like growth factor-I receptor gene expression in the primate ovary. Hum. Reprod. 1999, 14:2328-2332.
    • (1999) Hum. Reprod. , vol.14 , pp. 2328-2332
    • Vendola, K.1    Zhou, J.2    Wang, J.3    Bondy, C.A.4
  • 138
    • 0035971406 scopus 로고    scopus 로고
    • AP-1--Introductory remarks
    • Wagner E.F. AP-1--Introductory remarks. Oncogene 2001, 20:2334-2335.
    • (2001) Oncogene , vol.20 , pp. 2334-2335
    • Wagner, E.F.1
  • 139
    • 34250860909 scopus 로고    scopus 로고
    • Identification of androgen response elements in the insulin-like growth factor I upstream promoter
    • Wu Y., Zhao W., Zhao J., Pan J., Wu Q., Zhang Y., Bauman W.A., Cardozo C.P. Identification of androgen response elements in the insulin-like growth factor I upstream promoter. Endocrinology 2007, 148:2984-2993.
    • (2007) Endocrinology , vol.148 , pp. 2984-2993
    • Wu, Y.1    Zhao, W.2    Zhao, J.3    Pan, J.4    Wu, Q.5    Zhang, Y.6    Bauman, W.A.7    Cardozo, C.P.8
  • 140
    • 0027272979 scopus 로고
    • The effect of recombinant human growth hormone on regulation of growth hormone secretion and blood glucose in insulin-dependent diabetes
    • Wurzburger M.I., Prelevic G.M., Sonksen P.H., Balint-Peric L.A., Wheeler M. The effect of recombinant human growth hormone on regulation of growth hormone secretion and blood glucose in insulin-dependent diabetes. J. Clin. Endocrinol. Metab. 1993, 77:267-272.
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , pp. 267-272
    • Wurzburger, M.I.1    Prelevic, G.M.2    Sonksen, P.H.3    Balint-Peric, L.A.4    Wheeler, M.5
  • 141
    • 0032937419 scopus 로고    scopus 로고
    • Characterization of insulin-like growth factor binding protein-3 (IGFBP-3) binding to human breast cancer cells: Kinetics of IGFBP-3 binding and identification of receptor binding domain on the IGFBP-3 molecule
    • Yamanaka Y., Fowlkes J.L., Wilson E.M., Rosenfeld R.G., Oh Y. Characterization of insulin-like growth factor binding protein-3 (IGFBP-3) binding to human breast cancer cells: Kinetics of IGFBP-3 binding and identification of receptor binding domain on the IGFBP-3 molecule. Endocrinology 1999, 140:1319-1328.
    • (1999) Endocrinology , vol.140 , pp. 1319-1328
    • Yamanaka, Y.1    Fowlkes, J.L.2    Wilson, E.M.3    Rosenfeld, R.G.4    Oh, Y.5
  • 142
    • 79951527527 scopus 로고    scopus 로고
    • Altered prostate epithelial development and IGF-I signal in mice lacking the androgen receptor in stromal smooth muscle cells
    • Yu S., Zhang C., Lin C.C., Niu Y., Lai K.P., Chang H.C., Yeh S.D., Chang C., Yeh S. Altered prostate epithelial development and IGF-I signal in mice lacking the androgen receptor in stromal smooth muscle cells. Prostate 2011, 71:7.
    • (2011) Prostate , vol.71 , pp. 7
    • Yu, S.1    Zhang, C.2    Lin, C.C.3    Niu, Y.4    Lai, K.P.5    Chang, H.C.6    Yeh, S.D.7    Chang, C.8    Yeh, S.9
  • 143
    • 0022494878 scopus 로고
    • Acute metabolic effects and half-lives of intravenously administered insulin like growth factors I and II in normal and hypophysectomized rats
    • Zapf J., Hauri C., Waldvogel M., Froesch E.R. Acute metabolic effects and half-lives of intravenously administered insulin like growth factors I and II in normal and hypophysectomized rats. J. Clin. Invest. 1986, 77:1768-1775.
    • (1986) J. Clin. Invest. , vol.77 , pp. 1768-1775
    • Zapf, J.1    Hauri, C.2    Waldvogel, M.3    Froesch, E.R.4
  • 145
    • 0026740350 scopus 로고
    • Effects of insulin-like growth factor-I on glucose tolerance, insulin levels, and insulin secretion
    • Zenobi P.D., Graf S., Ursprung H., Froesch E.R. Effects of insulin-like growth factor-I on glucose tolerance, insulin levels, and insulin secretion. J. Clin. Invest. 1992, 89:1908-1913.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1908-1913
    • Zenobi, P.D.1    Graf, S.2    Ursprung, H.3    Froesch, E.R.4
  • 146
    • 0027074505 scopus 로고
    • Insulin-like growth factor-I improves glucose and lipid metabolism in type 2 diabetes mellitus
    • Zenobi P.D., Jaeggi-Groisman S.E., Riesen W.F., Roder M.E., Froesch E.R. Insulin-like growth factor-I improves glucose and lipid metabolism in type 2 diabetes mellitus. J. Clin. Invest. 1992, 90:2234-2241.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2234-2241
    • Zenobi, P.D.1    Jaeggi-Groisman, S.E.2    Riesen, W.F.3    Roder, M.E.4    Froesch, E.R.5
  • 147
    • 2442421050 scopus 로고    scopus 로고
    • Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: The phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals
    • Zhang D., Bar-Eli M., Meloche S., Brodt P. Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: The phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals. J. Biol. Chem. 2004, 279:19683-19690.
    • (2004) J. Biol. Chem. , vol.279 , pp. 19683-19690
    • Zhang, D.1    Bar-Eli, M.2    Meloche, S.3    Brodt, P.4


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