Synthesis and biological evaluation of the glycoside (25R)-3β, 16β-diacetoxy-22-oxocholest-5-en-26-yl β-d-glucopyranoside: A selective anticancer agent in cervicouterine cell lines

European Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2011, Pages 3877-3886

  Fernández Herrera, María A ^a,b   López Muñoz, Hugo ^c   Hernández Vázquez, José M V ^c   López Dávila, Moisés ^c   Mohan, Sankar ^b   Escobar Sánchez, María L ^d   Sánchez Sánchez, Luis ^c   Pinto, B Mario ^b   Sandoval Ramírez, Jesús ^a  

^a BENEMÉRITA UNIVERSIDAD AUTÓNOMA DE PUEBLA   (Mexico)

^b SIMON FRASER UNIVERSITY   (Canada)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Antiproliferative activity; Apoptosis; CaSki; Cholestane glycoside; HeLa; ViBo

Indexed keywords

3BETA,16BETA DIACETOXY 22 OXOCHOLEST 5 EN 26 YL BETA GLUCOPYRANOSIDE; AGLYCONE; ANTINEOPLASTIC AGENT; CASPASE 3; LACTATE DEHYDROGENASE; SAPONIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; HELA CELL; HUMAN; HUMAN TISSUE; IC 50; IN VITRO STUDY; LACTATE DEHYDROGENASE BLOOD LEVEL; PROTEIN EXPRESSION; UTERINE CERVIX CANCER;

ANTINEOPLASTIC AGENTS; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CHOLESTEROL; DNA FRAGMENTATION; FEMALE; GLUCOSIDES; HUMANS; LYMPHOCYTES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE; UTERINE CERVICAL NEOPLASMS;

EID: 80052933160     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.05.058     Document Type: Article

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