Gene expression and generation of CD28-CD8 T cells mediated by interleukin 15

Experimental Gerontology

Volumn 42, Issue 5 SPEC. ISS., 2007, Pages 412-415

  Godlove, Jason ^a   Chiu, Wai Kan ^a   Weng, Nan ping ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

Aging; Co stimulatory receptor; NK cell receptor

Indexed keywords

CD28 ANTIGEN; INTERLEUKIN 15; NATURAL KILLER CELL RECEPTOR;

CD8+ T LYMPHOCYTE; CELL GROWTH; CELL REGENERATION; DOWN REGULATION; GENE EXPRESSION; HUMAN; IMMUNOSTIMULATION; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; T LYMPHOCYTE ACTIVATION;

EID: 34147167064     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2006.11.015     Document Type: Short Survey

References (18)

1. Acuto O., and Michel F. CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat. Rev. Immunol. 3 (2003) 939-951
2. Azuma M., Phillips J.H., and Lanier L.L. CD28-T lymphocytes: antigenic and functional properties. J. Immunol. 150 (1993) 1147-1159
3. Biassoni R., Cantoni C., Marras D., Giron-Michel J., Falco M., Moretta L., and Dimasi N. Human natural killer cell receptors: insights into their molecular function and structure. J. Cell Mol. Med. 7 (2003) 376-387
4. Borthwick N.J., Lowdell M., Salmon M., and Akbar A.N. Loss of CD28 expression on CD8(+) T cells is induced by IL-2 receptor gamma chain signalling cytokines and type I IFN, and increases susceptibility to activation-induced apoptosis. Int. Immunol. 12 (2000) 1005-1013
5. Chiu W.K., Fann M., and Weng N.P. Generation and growth of CD28nullCD8+ memory T cells mediated by IL-15 and its induced cytokines. J. Immunol. 177 (2006) 7802-7810
6. Effros R.B., Allsopp R., Chiu C.P., Hausner M.A., Hirji K., Wang L., Harley C.B., Villeponteau B., West M.D., and Giorgi J.V. Shortened telomeres in the expanded CD28-CD8+ cell subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS 10 (1996) F17-F22
7. Fagnoni F.F., Vescovini R., Mazzola M., Bologna G., Nigro E., Lavagetto G., Franceschi C., Passeri M., and Sansoni P. Expansion of cytotoxic CD8+CD28-T cells in healthy ageing people, including centenarians. Immunology 88 (1996) 501-507
8. Fann M., Chiu W.K., Wood III W.H., Levine B.L., Becker K.G., and Weng N.P. Gene expression characteristics of CD28null memory phenotype CD8+ T cells and its implication in T-cell aging. Immunol. Rev. 205 (2005) 190-206
9. Fann M., Godlove J.M., Catalfamo M., Wood Iii W.H., Chrest F.J., Chun N., Granger L., Wersto R., Madara K., Becker K., Henkart P.A., and Weng N.P. Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8+ T cell response. Blood 108 (2006) 3363-3370
10. Nociari M.M., Telford W., and Russo C. Postthymic development of CD28-CD8+ T cell subset: age-associated expansion and shift from memory to naive phenotype. J. Immunol. 162 (1999) 3327-3335
11. Phillips J.H., Gumperz J.E., Parham P., and Lanier L.L. Superantigen-dependent, cell-mediated cytotoxicity inhibited by MHC class I receptors on T lymphocytes. Science 268 (1995) 403-405
12. Posnett D.N., Sinha R., Kabak S., and Russo C. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammapathy". J. Exp. Med. 179 (1994) 609-618
13. Riley J.L., and June C.H. The CD28 Family: a T cell rheostat for therapeutic control of T cell activation. Blood 105 (2005) 13-21
14. Saurwein-Teissl M., Lung T.L., Marx F., Gschosser C., Asch E., Blasko I., Parson W., Bock G., Schonitzer D., Trannoy E., and Grubeck-Loebenstein B. Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines. J. Immunol. 168 (2002) 5893-5899
15. Spaulding C., Guo W., and Effros R.B. Resistance to apoptosis in human CD8+ T cells that reach replicative senescence after multiple rounds of antigen-specific proliferation. Exp. Gerontol. 34 (1999) 633-644
16. Speiser D.E., Colonna M., Ayyoub M., Cella M., Pittet M.J., Batard P., Valmori D., Guillaume P., Lienard D., Cerottini J.C., and Romero P. The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells. J. Immunol. 167 (2001) 6165-6170
17. Watts T.H. TNF/TNFR family members in costimulation of T cell responses. Annu. Rev. Immunol. 23 (2005) 23-68
18. Weng N.P. Aging of the immune system: how much can the adaptive immune system adapt?. Immunity 24 (2006) 495-499