메뉴 건너뛰기




Volumn 289, Issue 2-3, 2011, Pages 122-131

Comparison of various iron chelators used in clinical practice as protecting agents against catecholamine-induced oxidative injury and cardiotoxicity

Author keywords

Catecholamine cardiotoxicity; Deferasirox (ICL670A); Deferiprone (L1); Desferrioxamine (DFO); Iron chelation

Indexed keywords

ADRENALIN; DEFERASIROX; DEFERIPRONE; DEFEROXAMINE; EDETIC ACID; IRON CHELATING AGENT; ISOPRENALINE; RAZOXANE;

EID: 80052769374     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2011.08.006     Document Type: Article
Times cited : (39)

References (61)
  • 1
    • 67650917155 scopus 로고    scopus 로고
    • Role of the excessive amounts of circulating catecholamines and glucocorticoids in stress-induced heart disease
    • Adameova A., Abdellatif Y., Dhalla N.S. Role of the excessive amounts of circulating catecholamines and glucocorticoids in stress-induced heart disease. Can. J. Physiol. Pharmacol. 2009, 87:493-514.
    • (2009) Can. J. Physiol. Pharmacol. , vol.87 , pp. 493-514
    • Adameova, A.1    Abdellatif, Y.2    Dhalla, N.S.3
  • 6
    • 0025980955 scopus 로고
    • The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons
    • Ben-Shachar D., Eshel G., Finberg J.P., Youdim M.B. The iron chelator desferrioxamine (Desferal) retards 6-hydroxydopamine-induced degeneration of nigrostriatal dopamine neurons. J. Neurochem. 1991, 56:1441-1444.
    • (1991) J. Neurochem. , vol.56 , pp. 1441-1444
    • Ben-Shachar, D.1    Eshel, G.2    Finberg, J.P.3    Youdim, M.B.4
  • 9
    • 79957950866 scopus 로고    scopus 로고
    • Contribution of catecholamine reactive intermediates and oxidative stress to the pathologic features of heart diseases
    • Costa V.M., Carvalho F., Bastos M.L., Carvalho R.A., Carvalho M., Remiao F. Contribution of catecholamine reactive intermediates and oxidative stress to the pathologic features of heart diseases. Curr. Med. Chem. 2011, 18:2272-2314.
    • (2011) Curr. Med. Chem. , vol.18 , pp. 2272-2314
    • Costa, V.M.1    Carvalho, F.2    Bastos, M.L.3    Carvalho, R.A.4    Carvalho, M.5    Remiao, F.6
  • 10
    • 0028215081 scopus 로고
    • The action of nine chelators on iron-dependent radical damage
    • Dean R.T., Nicholson P. The action of nine chelators on iron-dependent radical damage. Free Radic. Res. 1994, 20:83-101.
    • (1994) Free Radic. Res. , vol.20 , pp. 83-101
    • Dean, R.T.1    Nicholson, P.2
  • 11
    • 77956972089 scopus 로고    scopus 로고
    • Role of catecholamine oxidation in sudden cardiac death
    • Dhalla N.S., Adameova A., Kaur M. Role of catecholamine oxidation in sudden cardiac death. Fundam. Clin. Pharmacol. 2010, 24:539-546.
    • (2010) Fundam. Clin. Pharmacol. , vol.24 , pp. 539-546
    • Dhalla, N.S.1    Adameova, A.2    Kaur, M.3
  • 12
    • 0025677479 scopus 로고
    • Ameliorative effects of ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane] on the cardiotoxicity induced by doxorubicin or by isoproterenol in the mouse
    • Flandina C., Sanguedolce R., Rausa L., D'Alessandro N. Ameliorative effects of ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane] on the cardiotoxicity induced by doxorubicin or by isoproterenol in the mouse. Res. Commun. Chem. Pathol. Pharmacol. 1990, 70:259-272.
    • (1990) Res. Commun. Chem. Pathol. Pharmacol. , vol.70 , pp. 259-272
    • Flandina, C.1    Sanguedolce, R.2    Rausa, L.3    D'Alessandro, N.4
  • 13
    • 0035468951 scopus 로고    scopus 로고
    • Recent advances in the design of iron chelators against oxidative damage
    • Galey J.B. Recent advances in the design of iron chelators against oxidative damage. Mini Rev. Med. Chem. 2001, 1:233-242.
    • (2001) Mini Rev. Med. Chem. , vol.1 , pp. 233-242
    • Galey, J.B.1
  • 14
    • 0028196801 scopus 로고
    • Urinary and plasma catecholamines and urinary catecholamine metabolites in pheochromocytoma: diagnostic value in 19 cases
    • Gerlo E.A., Sevens C. Urinary and plasma catecholamines and urinary catecholamine metabolites in pheochromocytoma: diagnostic value in 19 cases. Clin. Chem. 1994, 40:250-256.
    • (1994) Clin. Chem. , vol.40 , pp. 250-256
    • Gerlo, E.A.1    Sevens, C.2
  • 15
    • 0038526391 scopus 로고    scopus 로고
    • Sources and significance of plasma levels of catechols and their metabolites in humans
    • Goldstein D.S., Eisenhofer G., Kopin I.J. Sources and significance of plasma levels of catechols and their metabolites in humans. J. Pharmacol. Exp. Ther. 2003, 305:800-811.
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 800-811
    • Goldstein, D.S.1    Eisenhofer, G.2    Kopin, I.J.3
  • 16
    • 0021337104 scopus 로고
    • Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site
    • Graf E., Mahoney J.R., Bryant R.G., Eaton J.W. Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site. J. Biol. Chem. 1984, 259:3620-3624.
    • (1984) J. Biol. Chem. , vol.259 , pp. 3620-3624
    • Graf, E.1    Mahoney, J.R.2    Bryant, R.G.3    Eaton, J.W.4
  • 17
    • 77956629759 scopus 로고    scopus 로고
    • Iron overload cardiomyopathy: better understanding of an increasing disorder
    • Gujja P., Rosing D.R., Tripodi D.J., Shizukuda Y. Iron overload cardiomyopathy: better understanding of an increasing disorder. J. Am. Coll. Cardiol. 2010, 56:1001-1012.
    • (2010) J. Am. Coll. Cardiol. , vol.56 , pp. 1001-1012
    • Gujja, P.1    Rosing, D.R.2    Tripodi, D.J.3    Shizukuda, Y.4
  • 19
    • 0036363028 scopus 로고    scopus 로고
    • Dexrazoxane (ICRF-187) protects cardiac myocytes against hypoxia-reoxygenation damage
    • Hasinoff B.B. Dexrazoxane (ICRF-187) protects cardiac myocytes against hypoxia-reoxygenation damage. Cardiovasc. Toxicol. 2002, 2:111-118.
    • (2002) Cardiovasc. Toxicol. , vol.2 , pp. 111-118
    • Hasinoff, B.B.1
  • 20
    • 79251623137 scopus 로고    scopus 로고
    • Iron chelation with salicylaldehyde isonicotinoyl hydrazone protects against catecholamine autooxidation and cardiotoxicity
    • Haskova P., Kovarikova P., Koubkova L., Vavrova A., Mackova E., Simunek T. Iron chelation with salicylaldehyde isonicotinoyl hydrazone protects against catecholamine autooxidation and cardiotoxicity. Free Radic. Biol. Med. 2011, 50:537-549.
    • (2011) Free Radic. Biol. Med. , vol.50 , pp. 537-549
    • Haskova, P.1    Kovarikova, P.2    Koubkova, L.3    Vavrova, A.4    Mackova, E.5    Simunek, T.6
  • 22
    • 0037630378 scopus 로고    scopus 로고
    • Role of deferiprone in chelation therapy for transfusional iron overload
    • Hoffbrand A.V., Cohen A., Hershko C. Role of deferiprone in chelation therapy for transfusional iron overload. Blood 2003, 102:17-24.
    • (2003) Blood , vol.102 , pp. 17-24
    • Hoffbrand, A.V.1    Cohen, A.2    Hershko, C.3
  • 23
    • 79954642381 scopus 로고    scopus 로고
    • Advances in metal-induced oxidative stress and human disease
    • Jomova K., Valko M. Advances in metal-induced oxidative stress and human disease. Toxicology 2011, 283:65-87.
    • (2011) Toxicology , vol.283 , pp. 65-87
    • Jomova, K.1    Valko, M.2
  • 24
    • 29844457587 scopus 로고    scopus 로고
    • The evolution of iron chelators for the treatment of iron overload disease and cancer
    • Kalinowski D.S., Richardson D.R. The evolution of iron chelators for the treatment of iron overload disease and cancer. Pharmacol. Rev. 2005, 57:547-583.
    • (2005) Pharmacol. Rev. , vol.57 , pp. 547-583
    • Kalinowski, D.S.1    Richardson, D.R.2
  • 25
    • 78649444888 scopus 로고    scopus 로고
    • Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples
    • Kell D.B. Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples. Arch. Toxicol. 2010, 84:825-889.
    • (2010) Arch. Toxicol. , vol.84 , pp. 825-889
    • Kell, D.B.1
  • 26
    • 0017232346 scopus 로고
    • Properties of a clonal muscle cell line from rat heart
    • Kimes B.W., Brandt B.L. Properties of a clonal muscle cell line from rat heart. Exp. Cell Res. 1976, 98:367-381.
    • (1976) Exp. Cell Res. , vol.98 , pp. 367-381
    • Kimes, B.W.1    Brandt, B.L.2
  • 27
    • 78650750565 scopus 로고    scopus 로고
    • Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites-the cardioprotectant dexrazoxane as a model case
    • Kovarikova P., Stariat J., Klimes J., Hruskova K., Vavrova K. Hydrophilic interaction liquid chromatography in the separation of a moderately lipophilic drug from its highly polar metabolites-the cardioprotectant dexrazoxane as a model case. J. Chromatogr. A 2011, 1218:416-426.
    • (2011) J. Chromatogr. A , vol.1218 , pp. 416-426
    • Kovarikova, P.1    Stariat, J.2    Klimes, J.3    Hruskova, K.4    Vavrova, K.5
  • 30
    • 45749092571 scopus 로고    scopus 로고
    • Protection against hydrogen peroxide-mediated cytotoxicity in Friedreich's ataxia fibroblasts using novel iron chelators of the 2-pyridylcarboxaldehyde isonicotinoyl hydrazone class
    • Lim C.K., Kalinowski D.S., Richardson D.R. Protection against hydrogen peroxide-mediated cytotoxicity in Friedreich's ataxia fibroblasts using novel iron chelators of the 2-pyridylcarboxaldehyde isonicotinoyl hydrazone class. Mol. Pharmacol. 2008, 74:225-235.
    • (2008) Mol. Pharmacol. , vol.74 , pp. 225-235
    • Lim, C.K.1    Kalinowski, D.S.2    Richardson, D.R.3
  • 33
    • 32644454767 scopus 로고    scopus 로고
    • The role of reactive oxygen and nitrogen species in cellular iron metabolism
    • Mladenka P., Simunek T., Hubl M., Hrdina R. The role of reactive oxygen and nitrogen species in cellular iron metabolism. Free Radic. Res. 2006, 40:263-272.
    • (2006) Free Radic. Res. , vol.40 , pp. 263-272
    • Mladenka, P.1    Simunek, T.2    Hubl, M.3    Hrdina, R.4
  • 34
    • 44649108912 scopus 로고    scopus 로고
    • Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells
    • Molina-Holgado F., Gaeta A., Francis P.T., Williams R.J., Hider R.C. Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells. J. Neurochem. 2008, 105:2466-2476.
    • (2008) J. Neurochem. , vol.105 , pp. 2466-2476
    • Molina-Holgado, F.1    Gaeta, A.2    Francis, P.T.3    Williams, R.J.4    Hider, R.C.5
  • 36
    • 0031001278 scopus 로고    scopus 로고
    • Iron-chelating therapy and the treatment of thalassemia
    • Olivieri N.F., Brittenham G.M. Iron-chelating therapy and the treatment of thalassemia. Blood 1997, 89:739-761.
    • (1997) Blood , vol.89 , pp. 739-761
    • Olivieri, N.F.1    Brittenham, G.M.2
  • 37
    • 70249126852 scopus 로고    scopus 로고
    • Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death
    • Popelova O., Sterba M., Haskova P., Simunek T., Hroch M., Guncova I., Nachtigal P., Adamcova M., Gersl V., Mazurova Y. Dexrazoxane-afforded protection against chronic anthracycline cardiotoxicity in vivo: effective rescue of cardiomyocytes from apoptotic cell death. Br. J. Cancer 2009, 101:792-802.
    • (2009) Br. J. Cancer , vol.101 , pp. 792-802
    • Popelova, O.1    Sterba, M.2    Haskova, P.3    Simunek, T.4    Hroch, M.5    Guncova, I.6    Nachtigal, P.7    Adamcova, M.8    Gersl, V.9    Mazurova, Y.10
  • 39
    • 33947304647 scopus 로고    scopus 로고
    • Preventive effect of naringin on isoproterenol-induced cardiotoxicity in Wistar rats: an in vivo and in vitro study
    • Rajadurai M., Prince P.S. Preventive effect of naringin on isoproterenol-induced cardiotoxicity in Wistar rats: an in vivo and in vitro study. Toxicology 2007, 232:216-225.
    • (2007) Toxicology , vol.232 , pp. 216-225
    • Rajadurai, M.1    Prince, P.S.2
  • 40
    • 85047677185 scopus 로고
    • Pretreatment with the iron chelator desferrioxamine fails to provide sustained protection against myocardial ischaemia-reperfusion injury
    • Reddy B.R., Wynne J., Kloner R.A., Przyklenk K. Pretreatment with the iron chelator desferrioxamine fails to provide sustained protection against myocardial ischaemia-reperfusion injury. Cardiovasc. Res. 1991, 25:711-718.
    • (1991) Cardiovasc. Res. , vol.25 , pp. 711-718
    • Reddy, B.R.1    Wynne, J.2    Kloner, R.A.3    Przyklenk, K.4
  • 41
    • 0026526023 scopus 로고
    • Ferritin as a source of iron for oxidative damage
    • Reif D.W. Ferritin as a source of iron for oxidative damage. Free Radic. Biol. Med. 1992, 12:417-427.
    • (1992) Free Radic. Biol. Med. , vol.12 , pp. 417-427
    • Reif, D.W.1
  • 42
    • 0035998297 scopus 로고    scopus 로고
    • Cu2+-induced isoproterenol oxidation into isoprenochrome in adult rat calcium-tolerant cardiomyocytes
    • Remiao F., Carvalho M., Carmo H., Carvalho F., Bastos M.L. Cu2+-induced isoproterenol oxidation into isoprenochrome in adult rat calcium-tolerant cardiomyocytes. Chem. Res. Toxicol. 2002, 15:861-869.
    • (2002) Chem. Res. Toxicol. , vol.15 , pp. 861-869
    • Remiao, F.1    Carvalho, M.2    Carmo, H.3    Carvalho, F.4    Bastos, M.L.5
  • 43
    • 50249171227 scopus 로고    scopus 로고
    • Neutral red uptake assay for the estimation of cell viability/cytotoxicity
    • Repetto G., del Peso A., Zurita J.L. Neutral red uptake assay for the estimation of cell viability/cytotoxicity. Nat. Protoc. 2008, 3:1125-1131.
    • (2008) Nat. Protoc. , vol.3 , pp. 1125-1131
    • Repetto, G.1    del Peso, A.2    Zurita, J.L.3
  • 44
    • 27844594297 scopus 로고    scopus 로고
    • EDTA chelation therapy for cardiovascular disease: a systematic review
    • Seely D.M., Wu P., Mills E.J. EDTA chelation therapy for cardiovascular disease: a systematic review. BMC Cardiovasc. Disord. 2005, 5:32.
    • (2005) BMC Cardiovasc. Disord. , vol.5 , pp. 32
    • Seely, D.M.1    Wu, P.2    Mills, E.J.3
  • 47
    • 66949171305 scopus 로고    scopus 로고
    • Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron
    • Simunek T., Sterba M., Popelova O., Adamcova M., Hrdina R., Gersl V. Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron. Pharmacol. Rep. 2009, 61:154-171.
    • (2009) Pharmacol. Rep. , vol.61 , pp. 154-171
    • Simunek, T.1    Sterba, M.2    Popelova, O.3    Adamcova, M.4    Hrdina, R.5    Gersl, V.6
  • 48
    • 50249149460 scopus 로고    scopus 로고
    • Anthracycline toxicity to cardiomyocytes or cancer cells is differently affected by iron chelation with salicylaldehyde isonicotinoyl hydrazone
    • Simunek T., Sterba M., Popelova O., Kaiserova H., Adamcova M., Hroch M., Haskova P., Ponka P., Gersl V. Anthracycline toxicity to cardiomyocytes or cancer cells is differently affected by iron chelation with salicylaldehyde isonicotinoyl hydrazone. Br. J. Pharmacol. 2008, 155:138-148.
    • (2008) Br. J. Pharmacol. , vol.155 , pp. 138-148
    • Simunek, T.1    Sterba, M.2    Popelova, O.3    Kaiserova, H.4    Adamcova, M.5    Hroch, M.6    Haskova, P.7    Ponka, P.8    Gersl, V.9
  • 50
    • 34247631275 scopus 로고    scopus 로고
    • Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
    • Sulzer D. Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease. Trends Neurosci. 2007, 30:244-250.
    • (2007) Trends Neurosci. , vol.30 , pp. 244-250
    • Sulzer, D.1
  • 51
    • 0018777993 scopus 로고
    • Studies in desferrioxamine and ferrioxamine metabolism in normal and iron-loaded subjects
    • Summers M.R., Jacobs A., Tudway D., Perera P., Ricketts C. Studies in desferrioxamine and ferrioxamine metabolism in normal and iron-loaded subjects. Br. J. Haematol. 1979, 42:547-555.
    • (1979) Br. J. Haematol. , vol.42 , pp. 547-555
    • Summers, M.R.1    Jacobs, A.2    Tudway, D.3    Perera, P.4    Ricketts, C.5
  • 52
    • 33644641768 scopus 로고    scopus 로고
    • Oxidative stress, accumulation of biological 'garbage', and aging
    • Terman A., Brunk U.T. Oxidative stress, accumulation of biological 'garbage', and aging. Antioxid. Redox Signal. 2006, 8:197-204.
    • (2006) Antioxid. Redox Signal. , vol.8 , pp. 197-204
    • Terman, A.1    Brunk, U.T.2
  • 53
    • 18544371009 scopus 로고    scopus 로고
    • Metals, toxicity and oxidative stress
    • Valko M., Morris H., Cronin M.T. Metals, toxicity and oxidative stress. Curr. Med. Chem. 2005, 12:1161-1208.
    • (2005) Curr. Med. Chem. , vol.12 , pp. 1161-1208
    • Valko, M.1    Morris, H.2    Cronin, M.T.3
  • 54
    • 0024402583 scopus 로고
    • Prevention of postischemic cardiac injury by the orally active iron chelator 1,2-dimethyl-3-hydroxy-4-pyridone (L1) and the antioxidant (+)-cyanidanol-3
    • van der Kraaij A.M., van Eijk H.G., Koster J.F. Prevention of postischemic cardiac injury by the orally active iron chelator 1,2-dimethyl-3-hydroxy-4-pyridone (L1) and the antioxidant (+)-cyanidanol-3. Circulation 1989, 80:158-164.
    • (1989) Circulation , vol.80 , pp. 158-164
    • van der Kraaij, A.M.1    van Eijk, H.G.2    Koster, J.F.3
  • 55
    • 0026465234 scopus 로고
    • Low molecular weight iron and the oxygen paradox in isolated rat hearts
    • Voogd A., Sluiter W., van Eijk H.G., Koster J.F. Low molecular weight iron and the oxygen paradox in isolated rat hearts. J. Clin. Invest. 1992, 90:2050-2055.
    • (1992) J. Clin. Invest. , vol.90 , pp. 2050-2055
    • Voogd, A.1    Sluiter, W.2    van Eijk, H.G.3    Koster, J.F.4
  • 56
    • 0032820452 scopus 로고    scopus 로고
    • Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader
    • Wang H., Joseph J.A. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic. Biol. Med. 1999, 27:612-616.
    • (1999) Free Radic. Biol. Med. , vol.27 , pp. 612-616
    • Wang, H.1    Joseph, J.A.2
  • 57
    • 0027368214 scopus 로고
    • Failure of deferoxamine to reduce myocardial infarct size in a primate model of ischemia-reperfusion injury
    • Watanabe B.I., Limm W., Suehiro A., Suehiro G., Premaratne S., McNamara J.J. Failure of deferoxamine to reduce myocardial infarct size in a primate model of ischemia-reperfusion injury. J. Surg. Res. 1993, 55:537-542.
    • (1993) J. Surg. Res. , vol.55 , pp. 537-542
    • Watanabe, B.I.1    Limm, W.2    Suehiro, A.3    Suehiro, G.4    Premaratne, S.5    McNamara, J.J.6
  • 58
    • 57049104663 scopus 로고    scopus 로고
    • Cardiac iron across different transfusion-dependent diseases
    • Wood J.C. Cardiac iron across different transfusion-dependent diseases. Blood Rev. 2008, 22(Suppl. 2):S14-S21.
    • (2008) Blood Rev. , vol.22 , Issue.SUPPL. 2
    • Wood, J.C.1
  • 59
    • 73949143370 scopus 로고    scopus 로고
    • Cardiac complications in thalassemia major
    • Wood J.C. Cardiac complications in thalassemia major. Hemoglobin 2009, 33(Suppl. 1):S81-S86.
    • (2009) Hemoglobin , vol.33 , Issue.SUPPL. 1
    • Wood, J.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.