-
1
-
-
0036800592
-
A genetic view of iron homeostasis
-
ANDREWS, N.C. 2002. A genetic view of iron homeostasis. Semin. Hematol. 39: 227-234.
-
(2002)
Semin. Hematol.
, vol.39
, pp. 227-234
-
-
Andrews, N.C.1
-
2
-
-
0041672570
-
Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
-
GANZ, T. 2003. Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood 102: 783-788.
-
(2003)
Blood
, vol.102
, pp. 783-788
-
-
Ganz, T.1
-
4
-
-
0018164919
-
Non-specific serum iron in thalassaemia: An abnormal serum iron fraction of potential toxicity
-
HERSHKO, C., G. GRAHAM, G.W. BATES & E.A. RACHMILEWITZ. 1978. Non-specific serum iron in thalassaemia: an abnormal serum iron fraction of potential toxicity. Br. J. Haematol. 40: 255-263.
-
(1978)
Br. J. Haematol.
, vol.40
, pp. 255-263
-
-
Hershko, C.1
Graham, G.2
Bates, G.W.3
Rachmilewitz, E.A.4
-
6
-
-
0029978555
-
Kinetics of removal and reappearance of non-transferrin-bound plasma iron with deferoxamine therapy
-
PORTER, J.B., R.D. ABEYSINGHE, L. MARSHALL, et al. 1996. Kinetics of removal and reappearance of non-transferrin-bound plasma iron with deferoxamine therapy. Blood 88: 705-713.
-
(1996)
Blood
, vol.88
, pp. 705-713
-
-
Porter, J.B.1
Abeysinghe, R.D.2
Marshall, L.3
-
7
-
-
0022111669
-
Heart cells in culture: A model of myocardial iron overload and chelation
-
LINK, G., A. PINSON & C. HERSHKO. 1985. Heart cells in culture: a model of myocardial iron overload and chelation. J. Lab. Clin. Med. 106: 147-153.
-
(1985)
J. Lab. Clin. Med.
, vol.106
, pp. 147-153
-
-
Link, G.1
Pinson, A.2
Hershko, C.3
-
8
-
-
0024532167
-
Effect of iron loading on transmembrane potential, contraction and automaticity of rat ventricular muscle cells in culture
-
LINK, G., P. ATHIAS, A. GRYNBERG, et al. 1989. Effect of iron loading on transmembrane potential, contraction and automaticity of rat ventricular muscle cells in culture. J. Lab. Clin. Med. 113: 103-111.
-
(1989)
J. Lab. Clin. Med.
, vol.113
, pp. 103-111
-
-
Link, G.1
Athias, P.2
Grynberg, A.3
-
9
-
-
0029937713
-
Dynamics of the cytosolic chelatable iron pool of K562 cells
-
BREUER, W., S. EPSZTEJN & Z.I. CABANTCHIK. 1997. Dynamics of the cytosolic chelatable iron pool of K562 cells. FEBS Lett. 382: 304-308.
-
(1997)
FEBS Lett.
, vol.382
, pp. 304-308
-
-
Breuer, W.1
Epsztejn, S.2
Cabantchik, Z.I.3
-
12
-
-
0025754836
-
Expression of the genes for the ferritin H and L subunits in rat liver and heart. Evidence for tissue-specific regulations at pre- and post-translational levels
-
CAIRO, G., E. RAPPOCCIOLO, L. TACCHINI & L. SCHIAFFONATI. 1991. Expression of the genes for the ferritin H and L subunits in rat liver and heart. Evidence for tissue-specific regulations at pre- and post-translational levels. Biochem. J. 275: 813-816.
-
(1991)
Biochem. J.
, vol.275
, pp. 813-816
-
-
Cairo, G.1
Rappocciolo, E.2
Tacchini, L.3
Schiaffonati, L.4
-
13
-
-
0032078224
-
Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells
-
LINK, G., A. SAADA, A. PINSON, et al. 1998. Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells. J. Lab. Clin. Med. 131: 466-474.
-
(1998)
J. Lab. Clin. Med.
, vol.131
, pp. 466-474
-
-
Link, G.1
Saada, A.2
Pinson, A.3
-
14
-
-
0028294163
-
The ability of orally effective iron chelators dimethyl- and diethyl-hydroxypyrid-4-one and of deferoxamine to restore sarcolemmal thiolic enzyme activity in iron-loaded heart cells
-
LINK, G., A. PINSON & C. HERSHKO. 1994. The ability of orally effective iron chelators dimethyl- and diethyl-hydroxypyrid-4-one and of deferoxamine to restore sarcolemmal thiolic enzyme activity in iron-loaded heart cells. Blood 83: 2692-2697.
-
(1994)
Blood
, vol.83
, pp. 2692-2697
-
-
Link, G.1
Pinson, A.2
Hershko, C.3
-
15
-
-
0023751318
-
Effects of acute iron loading on contractility and spontaneous beating rate of cultured rat myocardial cells
-
MOREB, J., C. HERSHKO & Y. HASIN. 1988. Effects of acute iron loading on contractility and spontaneous beating rate of cultured rat myocardial cells. Basic Res. Cardiol. 83: 360-368.
-
(1988)
Basic Res. Cardiol.
, vol.83
, pp. 360-368
-
-
Moreb, J.1
Hershko, C.2
Hasin, Y.3
-
16
-
-
3042746877
-
Value of sequential monitoring of left ventricular ejection fraction in the management of thalassemia major
-
DAVIS, B.A., C. O'SULLIVAN, P.H. JARRITT, et al. 2004. Value of sequential monitoring of left ventricular ejection fraction in the management of thalassemia major. Blood 104: 263-269.
-
(2004)
Blood
, vol.104
, pp. 263-269
-
-
Davis, B.A.1
O'Sullivan, C.2
Jarritt, P.H.3
-
17
-
-
0034651775
-
Long-term outcome of continuous 24-hour deferoxamine infusion via indwelling intravenous catheters in high-risk beta-thalassemia
-
DAVIS, B.A. & J.B. PORTER. 2000. Long-term outcome of continuous 24-hour deferoxamine infusion via indwelling intravenous catheters in high-risk beta-thalassemia. Blood 95: 1229-1236.
-
(2000)
Blood
, vol.95
, pp. 1229-1236
-
-
Davis, B.A.1
Porter, J.B.2
-
18
-
-
0038133426
-
Reversal of cardiac complications in thalassemia major by long-term intermittent daily intensive iron chelation Eur
-
MISKIN, H., I. YANIV, M. BERANT, et al. 2003. Reversal of cardiac complications in thalassemia major by long-term intermittent daily intensive iron chelation Eur. J. Haematol. 70: 398-403.
-
(2003)
J. Haematol.
, vol.70
, pp. 398-403
-
-
Miskin, H.1
Yaniv, I.2
Berant, M.3
-
19
-
-
0034631379
-
Survival in beta-thalassaemia major in the UK: Data from the UK Thalassaemia Register
-
MODELL, B., M. KHAN & M. DARLISON. 2000. Survival in beta-thalassaemia major in the UK: data from the UK Thalassaemia Register. Lancet 355: 2051-2052.
-
(2000)
Lancet
, vol.355
, pp. 2051-2052
-
-
Modell, B.1
Khan, M.2
Darlison, M.3
-
20
-
-
3042758517
-
Complications of β-thalassemia major in North America
-
CUNNINGHAM, M.J., E.A. MACKLIN & E.J. NEUFELD. 2004. Complications of β-thalassemia major in North America. Blood 104: 34-39.
-
(2004)
Blood
, vol.104
, pp. 34-39
-
-
Cunningham, M.J.1
Macklin, E.A.2
Neufeld, E.J.3
-
21
-
-
27144540768
-
Iron chelation therapy, a better approach
-
Bangkok, Thailand, May-June 1999. Abstr. 0018
-
GRADY, R.W., V.A. BERDOUKAS, E.A. RACHMILEWITZ, et al. 1999. Iron chelation therapy, a better approach. The 7th International Conference on Thalassaemia and the Haemoglobinopathies. Bangkok, Thailand, May-June 1999. Abstr. 0018.
-
(1999)
The 7th International Conference on Thalassaemia and the Haemoglobinopathies
-
-
Grady, R.W.1
Berdoukas, V.A.2
Rachmilewitz, E.A.3
-
22
-
-
0032887235
-
Deferiprone. A review of its clinical potential in iron overload in β-thalassaemia major and other transfusion-dependent diseases
-
BARMAN BALFOUR, J.A. & R.H. FOSTER. 1999. Deferiprone. A review of its clinical potential in iron overload in β-thalassaemia major and other transfusion-dependent diseases. Drugs 58: 553-578.
-
(1999)
Drugs
, vol.58
, pp. 553-578
-
-
Barman Balfour, J.A.1
Foster, R.H.2
-
23
-
-
0037630378
-
Role of deferiprone in chelation therapy for transfusional iron overload
-
HOFFBRAND, A.V., A. COHEN & C. HERSHKO. 2003. Role of deferiprone in chelation therapy for transfusional iron overload. Blood 102: 17-24.
-
(2003)
Blood
, vol.102
, pp. 17-24
-
-
Hoffbrand, A.V.1
Cohen, A.2
Hershko, C.3
-
24
-
-
18444390877
-
Deferiprone versus deferoxamine in patients with thalassemia major: A randomized clinical trial
-
MAGGIO, A., G. D'AMICO, A. MORABITO, et al. 2002. Deferiprone versus deferoxamine in patients with thalassemia major: a randomized clinical trial. Blood Cells Mol. Dis. 28: 196-208.
-
(2002)
Blood Cells Mol. Dis.
, vol.28
, pp. 196-208
-
-
Maggio, A.1
D'Amico, G.2
Morabito, A.3
-
25
-
-
0038187626
-
Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: A retrospective analysis
-
PIGA, A., C. GAGLIOTI, E. FOGLIACCO, et al. 2003. Comparative effects of deferiprone and deferoxamine on survival and cardiac disease in patients with thalassemia major: a retrospective analysis. Haematologica 88: 489-496.
-
(2003)
Haematologica
, vol.88
, pp. 489-496
-
-
Piga, A.1
Gaglioti, C.2
Fogliacco, E.3
-
26
-
-
0037125595
-
Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia
-
ANDERSON, L.J., B. WONKE, E. PRESCOTT, et al. 2002. Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Lancet 360: 516-520.
-
(2002)
Lancet
, vol.360
, pp. 516-520
-
-
Anderson, L.J.1
Wonke, B.2
Prescott, E.3
-
27
-
-
0027433891
-
Contrasting interspecies efficacy and toxicology of 1,2-diethyl-3- hydroxypyrid-4-one, CP94, relates to different metabolism of the iron chelating site
-
PORTER, J.B., R.D. ABEYSINGHE, K.P. HOYES, et al. 1993. Contrasting interspecies efficacy and toxicology of 1,2-diethyl-3-hydroxypyrid-4-one, CP94, relates to different metabolism of the iron chelating site. Br. J. Haematol. 85: 159-168.
-
(1993)
Br. J. Haematol.
, vol.85
, pp. 159-168
-
-
Porter, J.B.1
Abeysinghe, R.D.2
Hoyes, K.P.3
-
28
-
-
0027486590
-
Subcellular distribution of desferrioxamine and hydroxypyridin-4-one chelators in K562 cells affects chelation of intracellular iron pools
-
HOYES, K.P. & J.B. PORTER. 1993. Subcellular distribution of desferrioxamine and hydroxypyridin-4-one chelators in K562 cells affects chelation of intracellular iron pools. Br. J. Haematol. 85: 393-400.
-
(1993)
Br. J. Haematol.
, vol.85
, pp. 393-400
-
-
Hoyes, K.P.1
Porter, J.B.2
-
29
-
-
0025817843
-
Iron mobilization from myocardial cells by 3-hydroxypyridin-4-one chelators: Studies in rat heart cells in culture
-
HERSHKO, C., G. LINK, A. PINSON, et al. 1991. Iron mobilization from myocardial cells by 3-hydroxypyridin-4-one chelators: studies in rat heart cells in culture. Blood 77: 2049-2053.
-
(1991)
Blood
, vol.77
, pp. 2049-2053
-
-
Hershko, C.1
Link, G.2
Pinson, A.3
-
30
-
-
0028962119
-
Pharmacokinetics of the oral iron chelator deferiprone (L1) in patients with iron overload
-
AL-REFAIE, F.N., L.N. SHEPPARD, P. NORTEY, et al. 1995. Pharmacokinetics of the oral iron chelator deferiprone (L1) in patients with iron overload Br. J. Haematol. 89: 403-407.
-
(1995)
Br. J. Haematol.
, vol.89
, pp. 403-407
-
-
Al-Refaie, F.N.1
Sheppard, L.N.2
Nortey, P.3
-
31
-
-
0032055861
-
Pyridoxal isonicotinoyl hydrazone and its analogs: Potential orally effective iron-chelating agents for the treatment of iron overload disease
-
RICHARDSON, D.R. & P. PONKA. 1998. Pyridoxal isonicotinoyl hydrazone and its analogs: potential orally effective iron-chelating agents for the treatment of iron overload disease. J. Lab. Clin. Med. 131: 306-314.
-
(1998)
J. Lab. Clin. Med.
, vol.131
, pp. 306-314
-
-
Richardson, D.R.1
Ponka, P.2
-
32
-
-
0037906104
-
Safety, tolerability and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron-overload due to beta-thalassemia
-
GALANELLO, R., A. PIGA, D. ALBERTI, et al. 2003. Safety, tolerability and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron-overload due to beta-thalassemia. J. Clin. Pharmacol. 43: 565-572.
-
(2003)
J. Clin. Pharmacol.
, vol.43
, pp. 565-572
-
-
Galanello, R.1
Piga, A.2
Alberti, D.3
-
33
-
-
0042309610
-
Structure-activity relationships among desazadesferrithiocin analogues
-
BERGERON, R.J., J. WIEGAND, J.S. MCMANIS, et al. 2002. Structure-activity relationships among desazadesferrithiocin analogues. Adv. Exp. Med. Biol. 509: 167-184.
-
(2002)
Adv. Exp. Med. Biol.
, vol.509
, pp. 167-184
-
-
Bergeron, R.J.1
Wiegand, J.2
Mcmanis, J.S.3
-
34
-
-
0035254193
-
Deferoxamine-chelatable iron, a component of serum non-transferrin-bound iron, used for assessing chelation therapy
-
BREUER, W., M.J. EMPERS, P. POOTRAKUL, et al. 2001. Deferoxamine- chelatable iron, a component of serum non-transferrin-bound iron, used for assessing chelation therapy. Blood 97: 792-798.
-
(2001)
Blood
, vol.97
, pp. 792-798
-
-
Breuer, W.1
Empers, M.J.2
Pootrakul, P.3
-
35
-
-
0031784438
-
Combined therapy with deferiprone and desferrioxamine
-
WONKE, B., C. WRIGHT & A.V. HOFFBRAND. 1998. Combined therapy with deferiprone and desferrioxamine. Br. J. Haematol. 103: 361-364.
-
(1998)
Br. J. Haematol.
, vol.103
, pp. 361-364
-
-
Wonke, B.1
Wright, C.2
Hoffbrand, A.V.3
-
36
-
-
0003291393
-
Oral iron chelation: A potential role for HBED in combination therapy. American Society of Hematology, 41st Annual Meeting. December 1999
-
Abstr. 3293
-
GRADY, R.W. & P.J. GIARDINA. 1999. Oral iron chelation: a potential role for HBED in combination therapy. American Society of Hematology, 41st Annual Meeting. December 1999. Blood 94(Suppl. 1): Abstr. 3293.
-
(1999)
Blood
, vol.94
, Issue.SUPPL. 1
-
-
Grady, R.W.1
Giardina, P.J.2
-
37
-
-
0036068230
-
The safety and effectiveness of deferiprone in a large-scale 3-year study in Italian patients
-
CECI, A., P. BAIARDI, M. FELISI, et al. 2002. The safety and effectiveness of deferiprone in a large-scale 3-year study in Italian patients. Br. J. Haematol. 118: 330-336.
-
(2002)
Br. J. Haematol.
, vol.118
, pp. 330-336
-
-
Ceci, A.1
Baiardi, P.2
Felisi, M.3
-
38
-
-
0031985039
-
Long-term trial of deferiprone in transfusion-dependent iron overloaded patients
-
HOFFBRAND, A.V., F. AL-REFAIE, B. DAVIS, et al. 1998. Long-term trial of deferiprone in transfusion-dependent iron overloaded patients. Blood 91: 295-300.
-
(1998)
Blood
, vol.91
, pp. 295-300
-
-
Hoffbrand, A.V.1
Al-Refaie, F.2
Davis, B.3
|