-
1
-
-
0037125595
-
Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia
-
Anderson LJ, Wonke B, Prescott E, Holden S, Walker JM, and Pennell DJ (2002) Comparison of effects of oral deferiprone and subcutaneous desferrioxamine on myocardial iron concentrations and ventricular function in beta-thalassaemia. Lancet 360:516-520.
-
(2002)
Lancet
, vol.360
, pp. 516-520
-
-
Anderson, L.J.1
Wonke, B.2
Prescott, E.3
Holden, S.4
Walker, J.M.5
Pennell, D.J.6
-
3
-
-
34548301545
-
Protection by flavonoids against anthracycline cardiotoxicity: From chemistry to clinical trials
-
Bast A, Haenen GR, Bruynzeel AM, and Van der Vijgh WJ (2007) Protection by flavonoids against anthracycline cardiotoxicity: from chemistry to clinical trials. Cardiovasc Toxicol 7:154-159.
-
(2007)
Cardiovasc Toxicol
, vol.7
, pp. 154-159
-
-
Bast, A.1
Haenen, G.R.2
Bruynzeel, A.M.3
Van der Vijgh, W.J.4
-
4
-
-
34548336833
-
Molecular and cellular mechanisms of anthracycline cardiotoxicity
-
Chen B, Peng X, Pentassuglia L, Lim CC, and Sawyer DB (2007) Molecular and cellular mechanisms of anthracycline cardiotoxicity. Cardiovasc Toxicol 7:114-121.
-
(2007)
Cardiovasc Toxicol
, vol.7
, pp. 114-121
-
-
Chen, B.1
Peng, X.2
Pentassuglia, L.3
Lim, C.C.4
Sawyer, D.B.5
-
5
-
-
0036310616
-
Pharmacokineticpharmacodynamic relationships of the anthracycline anticancer drugs
-
Danesi R, Fogli S, Gennari A, Conte P, and Del Tacca M (2002) Pharmacokineticpharmacodynamic relationships of the anthracycline anticancer drugs. Clin Pharmacokinet 41:431-444.
-
(2002)
Clin Pharmacokinet
, vol.41
, pp. 431-444
-
-
Danesi, R.1
Fogli, S.2
Gennari, A.3
Conte, P.4
Del Tacca, M.5
-
6
-
-
0020395312
-
Prospective randomized study of the role of N-acetyl cysteine in reversing doxorubicin-induced cardiomyopathy
-
Dresdale AR, Barr LH, Bonow RO, Mathisen DJ, Myers CE, Schwartz DE, d'Angelo T, and Rosenberg SA (1982) Prospective randomized study of the role of N-acetyl cysteine in reversing doxorubicin-induced cardiomyopathy. Am J Clin Oncol 5:657-663.
-
(1982)
Am J Clin Oncol
, vol.5
, pp. 657-663
-
-
Dresdale, A.R.1
Barr, L.H.2
Bonow, R.O.3
Mathisen, D.J.4
Myers, C.E.5
Schwartz, D.E.6
d'Angelo, T.7
Rosenberg, S.A.8
-
7
-
-
0027483258
-
Pharmacokinetics of representative 3-hydroxypyridin-4-ones in rabbits: CP20 and CP94
-
Fredenburg AM, Wedlund PJ, Skinner TL, Damani LA, Hider RC, and Yokel RA (1993) Pharmacokinetics of representative 3-hydroxypyridin-4-ones in rabbits: CP20 and CP94. Drug Metab Dispos 21:255-258.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 255-258
-
-
Fredenburg, A.M.1
Wedlund, P.J.2
Skinner, T.L.3
Damani, L.A.4
Hider, R.C.5
Yokel, R.A.6
-
8
-
-
33750001927
-
Action of chelators in iron-loaded cardiac cells: Accessibility to intracellular labile iron and functional consequences
-
Glickstein H, El RB, Link G, Breuer W, Konijn AM, Hershko C, Nick H, and Cabantchik ZI (2006) Action of chelators in iron-loaded cardiac cells: accessibility to intracellular labile iron and functional consequences. Blood 108:3195-3203.
-
(2006)
Blood
, vol.108
, pp. 3195-3203
-
-
Glickstein, H.1
El, R.B.2
Link, G.3
Breuer, W.4
Konijn, A.M.5
Hershko, C.6
Nick, H.7
Cabantchik, Z.I.8
-
9
-
-
0035181433
-
Inhibition of malignant cell growth by 311, a novel iron chelator of the pyridoxal isonicotinoyl hydrazone class: Effect on the R2 subunit of ribonucleotide reductase
-
Green DA, Antholine WE, Wong SJ, Richardson DR, and Chitambar CR (2001) Inhibition of malignant cell growth by 311, a novel iron chelator of the pyridoxal isonicotinoyl hydrazone class: effect on the R2 subunit of ribonucleotide reductase. Clin Cancer Res 7:3574-3579.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3574-3579
-
-
Green, D.A.1
Antholine, W.E.2
Wong, S.J.3
Richardson, D.R.4
Chitambar, C.R.5
-
10
-
-
0031906718
-
Chemical, biological and clinical aspects of dexrazoxane and other bisdioxopiperazines
-
Hasinoff BB, Hellmann K, Herman EH, and Ferrans VJ (1998) Chemical, biological and clinical aspects of dexrazoxane and other bisdioxopiperazines. Curr Med Chem 5:1-28.
-
(1998)
Curr Med Chem
, vol.5
, pp. 1-28
-
-
Hasinoff, B.B.1
Hellmann, K.2
Herman, E.H.3
Ferrans, V.J.4
-
11
-
-
0345306160
-
The oral iron chelator ICL670A (deferasirox) does not protect myocytes against doxorubicin
-
Hasinoff BB, Patel D, and Wu X (2003) The oral iron chelator ICL670A (deferasirox) does not protect myocytes against doxorubicin. Free Radic Biol Med 35:1469-1479.
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 1469-1479
-
-
Hasinoff, B.B.1
Patel, D.2
Wu, X.3
-
12
-
-
0028080144
-
Comparison of the protective effects of desferrioxamine and ICRF-187 against doxorubicin-induced toxicity in spontaneously hypertensive rats
-
Herman EH, Zhang J, and Ferrans VJ (1994) Comparison of the protective effects of desferrioxamine and ICRF-187 against doxorubicin-induced toxicity in spontaneously hypertensive rats. Cancer Chemother Pharmacol 35:93-100.
-
(1994)
Cancer Chemother Pharmacol
, vol.35
, pp. 93-100
-
-
Herman, E.H.1
Zhang, J.2
Ferrans, V.J.3
-
13
-
-
0030744361
-
Comparison of the protective effects against chronic doxorubicin cardiotoxicity and the rates of iron (III) displacement reactions of ICRF-187 and other bisdiketopiperazines
-
Herman EH, Zhang J, Hasinoff BB, Chadwick DP, Clark JR Jr., and Ferrans VJ (1997) Comparison of the protective effects against chronic doxorubicin cardiotoxicity and the rates of iron (III) displacement reactions of ICRF-187 and other bisdiketopiperazines. Cancer Chemother Pharmacol 40:400-408.
-
(1997)
Cancer Chemother Pharmacol
, vol.40
, pp. 400-408
-
-
Herman, E.H.1
Zhang, J.2
Hasinoff, B.B.3
Chadwick, D.P.4
Clark Jr., J.R.5
Ferrans, V.J.6
-
14
-
-
0003633755
-
-
Institute of Laboratory Animal Resources , 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC
-
Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington DC.
-
(1996)
Guide for the Care and Use of Laboratory Animals
-
-
-
16
-
-
0025283897
-
Doxorubicin (adriamycin): A critical review of free radical-dependent mechanisms of cytotoxicity
-
Keizer HG, Pinedo HM, Schuurhuis GJ, and Joenje H (1990) Doxorubicin (adriamycin): a critical review of free radical-dependent mechanisms of cytotoxicity. Pharmacol Ther 47:219-231.
-
(1990)
Pharmacol Ther
, vol.47
, pp. 219-231
-
-
Keizer, H.G.1
Pinedo, H.M.2
Schuurhuis, G.J.3
Joenje, H.4
-
17
-
-
3242753676
-
The design and development of deferiprone (L1) and other iron chelators for clinical use: Targeting methods and application prospects
-
Kontoghiorghes GJ, Pattichis K, Neocleous K, and Kolnagou A (2004) The design and development of deferiprone (L1) and other iron chelators for clinical use: targeting methods and application prospects. Curr Med Chem 11:2161-2183.
-
(2004)
Curr Med Chem
, vol.11
, pp. 2161-2183
-
-
Kontoghiorghes, G.J.1
Pattichis, K.2
Neocleous, K.3
Kolnagou, A.4
-
18
-
-
0037379680
-
Anthracyclines induce accumulation of iron in ferritin in myocardial and neoplastic cells: Inhibition of the ferritin iron mobilization pathway
-
Kwok JC and Richardson DR (2003) Anthracyclines induce accumulation of iron in ferritin in myocardial and neoplastic cells: inhibition of the ferritin iron mobilization pathway. Mol Pharmacol 63:849-861.
-
(2003)
Mol Pharmacol
, vol.63
, pp. 849-861
-
-
Kwok, J.C.1
Richardson, D.R.2
-
19
-
-
34447573788
-
Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats
-
Lebrecht D, Geist A, Ketelsen UP, Haberstroh J, Setzer B, and Walker UA (2007) Dexrazoxane prevents doxorubicin-induced long-term cardiotoxicity and protects myocardial mitochondria from genetic and functional lesions in rats. Br J Pharmacol 151:771-778.
-
(2007)
Br J Pharmacol
, vol.151
, pp. 771-778
-
-
Lebrecht, D.1
Geist, A.2
Ketelsen, U.P.3
Haberstroh, J.4
Setzer, B.5
Walker, U.A.6
-
20
-
-
0020334080
-
Clinical and pharmacologic investigation of the effects of alpha-tocopherol on adriamycin cardiotoxicity
-
Legha SS, Wang YM, Mackay B, Ewer M, Hortobagyi GN, Benjamin RS, and Ali MK (1982) Clinical and pharmacologic investigation of the effects of alpha-tocopherol on adriamycin cardiotoxicity. Ann N Y Acad Sci 393:411-418.
-
(1982)
Ann N Y Acad Sci
, vol.393
, pp. 411-418
-
-
Legha, S.S.1
Wang, Y.M.2
Mackay, B.3
Ewer, M.4
Hortobagyi, G.N.5
Benjamin, R.S.6
Ali, M.K.7
-
21
-
-
34548675357
-
Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: A possible relationship with polyamine metabolism
-
Lescoat G, Chantrel-Groussard K, Pasdeloup N, Nick H, Brissot P, and Gaboriau F (2007) Antiproliferative and apoptotic effects in rat and human hepatoma cell cultures of the orally active iron chelator ICL670 compared to CP20: a possible relationship with polyamine metabolism. Cell Prolif 40:755-767.
-
(2007)
Cell Prolif
, vol.40
, pp. 755-767
-
-
Lescoat, G.1
Chantrel-Groussard, K.2
Pasdeloup, N.3
Nick, H.4
Brissot, P.5
Gaboriau, F.6
-
22
-
-
0030091567
-
Role of iron in the potentiation of anthracycline cardiotoxicity: Identification of heart cell mitochondria as a major site of iron-anthracycline interaction
-
Link G, Tirosh R, Pinson A, and Hershko C (1996) Role of iron in the potentiation of anthracycline cardiotoxicity: identification of heart cell mitochondria as a major site of iron-anthracycline interaction. J Lab Clin Med 127:272-278.
-
(1996)
J Lab Clin Med
, vol.127
, pp. 272-278
-
-
Link, G.1
Tirosh, R.2
Pinson, A.3
Hershko, C.4
-
23
-
-
34548301536
-
An introduction to the metabolic determinants of anthracycline cardiotoxicity
-
Menna P, Recalcati S, Cairo G, and Minotti G (2007) An introduction to the metabolic determinants of anthracycline cardiotoxicity. Cardiovasc Toxicol 7:80-85.
-
(2007)
Cardiovasc Toxicol
, vol.7
, pp. 80-85
-
-
Menna, P.1
Recalcati, S.2
Cairo, G.3
Minotti, G.4
-
24
-
-
2642566088
-
Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
-
Minotti G, Menna P, Salvatorelli E, Cairo G, and Gianni L (2004) Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 56:185-229.
-
(2004)
Pharmacol Rev
, vol.56
, pp. 185-229
-
-
Minotti, G.1
Menna, P.2
Salvatorelli, E.3
Cairo, G.4
Gianni, L.5
-
25
-
-
0020583667
-
A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by N-acetylcysteine
-
Myers C, Bonow R, Palmeri S, Jenkins J, Corden B, Locker G, Doroshow J, and Epstein S (1983) A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by N-acetylcysteine. Semin Oncol 10:53-55.
-
(1983)
Semin Oncol
, vol.10
, pp. 53-55
-
-
Myers, C.1
Bonow, R.2
Palmeri, S.3
Jenkins, J.4
Corden, B.5
Locker, G.6
Doroshow, J.7
Epstein, S.8
-
26
-
-
5144227343
-
Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity
-
Oliveira PJ, Bjork JA, Santos MS, Leino RL, Froberg MK, Moreno AJ, and Wallace KB (2004) Carvedilol-mediated antioxidant protection against doxorubicin-induced cardiac mitochondrial toxicity. Toxicol Appl Pharmacol 200:159-168.
-
(2004)
Toxicol Appl Pharmacol
, vol.200
, pp. 159-168
-
-
Oliveira, P.J.1
Bjork, J.A.2
Santos, M.S.3
Leino, R.L.4
Froberg, M.K.5
Moreno, A.J.6
Wallace, K.B.7
-
27
-
-
0034625677
-
Measurement of free and bound malondialdehyde in plasma by high-performance liquid chromatography as the 2,4-dinitrophenylhydrazine derivative
-
Pilz J, Meineke I, and Gleiter CH (2000) Measurement of free and bound malondialdehyde in plasma by high-performance liquid chromatography as the 2,4-dinitrophenylhydrazine derivative. J Chromatogr B Biomed Sci Appl 742:315-325.
-
(2000)
J Chromatogr B Biomed Sci Appl
, vol.742
, pp. 315-325
-
-
Pilz, J.1
Meineke, I.2
Gleiter, C.H.3
-
28
-
-
0025201168
-
Relative oral efficacy and acute toxicity of hydroxypyridin-4-one iron chelators in mice
-
Porter JB, Morgan J, Hoyes KP, Burke LC, Huehns ER, and Hider RC (1990) Relative oral efficacy and acute toxicity of hydroxypyridin-4-one iron chelators in mice. Blood 76:2389-2396.
-
(1990)
Blood
, vol.76
, pp. 2389-2396
-
-
Porter, J.B.1
Morgan, J.2
Hoyes, K.P.3
Burke, L.C.4
Huehns, E.R.5
Hider, R.C.6
-
29
-
-
27744528421
-
Molecular mechanisms of iron uptake by cells and the use of iron chelators for the treatment of cancer
-
Richardson DR (2005) Molecular mechanisms of iron uptake by cells and the use of iron chelators for the treatment of cancer. Curr Med Chem 12:2711-2729.
-
(2005)
Curr Med Chem
, vol.12
, pp. 2711-2729
-
-
Richardson, D.R.1
-
30
-
-
0034957066
-
The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats
-
Saad SY, Najjar TA, and Al-Rikabi AC (2001) The preventive role of deferoxamine against acute doxorubicin-induced cardiac, renal and hepatic toxicity in rats. Pharmacol Res 43:211-218.
-
(2001)
Pharmacol Res
, vol.43
, pp. 211-218
-
-
Saad, S.Y.1
Najjar, T.A.2
Al-Rikabi, A.C.3
-
31
-
-
2942618622
-
Rabbit model for in vivo study of anthracycline-induced heart failure and for the evaluation of protective agents
-
Simunek T, Klimtova I, Kaplanova J, Mazurova Y, Adamcova M, Sterba M, Hrdina R, and Gersl V (2004) Rabbit model for in vivo study of anthracycline-induced heart failure and for the evaluation of protective agents. Eur J Heart Fail 6:377-387.
-
(2004)
Eur J Heart Fail
, vol.6
, pp. 377-387
-
-
Simunek, T.1
Klimtova, I.2
Kaplanova, J.3
Mazurova, Y.4
Adamcova, M.5
Sterba, M.6
Hrdina, R.7
Gersl, V.8
-
32
-
-
12344319022
-
Study of daunorubicin cardiotoxicity prevention with pyridoxal isonicotinoyl hydrazone in rabbits
-
Simunek T, Klimtova I, Kaplanova J, Sterba M, Mazurova Y, Adamcova M, Hrdina R, Gersl V, and Ponka P (2005a) Study of daunorubicin cardiotoxicity prevention with pyridoxal isonicotinoyl hydrazone in rabbits. Pharmacol Res 51:223-231.
-
(2005)
Pharmacol Res
, vol.51
, pp. 223-231
-
-
Simunek, T.1
Klimtova, I.2
Kaplanova, J.3
Sterba, M.4
Mazurova, Y.5
Adamcova, M.6
Hrdina, R.7
Gersl, V.8
Ponka, P.9
-
33
-
-
17644416425
-
Myocardial content of selected elements in experimental anthracycline-induced cardiomyopathy in rabbits
-
Simunek T, Sterba M, Holeckova M, Kaplanova J, Klimtova I, Adamcova M, Gersl V, and Hrdina R (2005b) Myocardial content of selected elements in experimental anthracycline-induced cardiomyopathy in rabbits. Biometals 18:163-169.
-
(2005)
Biometals
, vol.18
, pp. 163-169
-
-
Simunek, T.1
Sterba, M.2
Holeckova, M.3
Kaplanova, J.4
Klimtova, I.5
Adamcova, M.6
Gersl, V.7
Hrdina, R.8
-
34
-
-
34248384887
-
Iron chelation-afforded cardioprotection against chronic anthracycline cardiotoxicity: A study of salicylaldehyde isonicotinoyl hydrazone (SIH)
-
Sterba M, Popelova O, Simunek T, Mazurova Y, Potacova A, Adamcova M, Guncova I, Kaiserova H, Palicka V, Ponka P, et al. (2007a) Iron chelation-afforded cardioprotection against chronic anthracycline cardiotoxicity: a study of salicylaldehyde isonicotinoyl hydrazone (SIH). Toxicology 235:150-166.
-
(2007)
Toxicology
, vol.235
, pp. 150-166
-
-
Sterba, M.1
Popelova, O.2
Simunek, T.3
Mazurova, Y.4
Potacova, A.5
Adamcova, M.6
Guncova, I.7
Kaiserova, H.8
Palicka, V.9
Ponka, P.10
-
35
-
-
33751187356
-
Cardioprotective effects of a novel iron chelator, pyridoxal 2-chlorobenzoyl hydrazone, in the rabbit model of daunorubicin-induced cardiotoxicity
-
Sterba M, Popelova O, Simunek T, Mazurova Y, Potacova A, Adamcova M, Kaiserova H, Ponka P, and Gersl V (2006) Cardioprotective effects of a novel iron chelator, pyridoxal 2-chlorobenzoyl hydrazone, in the rabbit model of daunorubicin-induced cardiotoxicity. J Pharmacol Exp Ther 319:1336-1347.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 1336-1347
-
-
Sterba, M.1
Popelova, O.2
Simunek, T.3
Mazurova, Y.4
Potacova, A.5
Adamcova, M.6
Kaiserova, H.7
Ponka, P.8
Gersl, V.9
-
36
-
-
36849022195
-
Early detection of anthracycline cardiotoxicity in a rabbit model: Left ventricle filling pattern versus troponin T determination
-
Sterba M, Simunek T, Popelova O, Potacova A, Adamcova M, Mazurova Y, Holeckova M, and Gersl V (2007b) Early detection of anthracycline cardiotoxicity in a rabbit model: left ventricle filling pattern versus troponin T determination. Physiol Res 56:535-545.
-
(2007)
Physiol Res
, vol.56
, pp. 535-545
-
-
Sterba, M.1
Simunek, T.2
Popelova, O.3
Potacova, A.4
Adamcova, M.5
Mazurova, Y.6
Holeckova, M.7
Gersl, V.8
-
37
-
-
42749107115
-
Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy
-
CD005008
-
van Dalen EC, van der Pal HJ, Caron HN, and Kremer LC (2006) Different dosage schedules for reducing cardiotoxicity in cancer patients receiving anthracycline chemotherapy. Cochrane Database Syst Rev:CD005008.
-
(2006)
Cochrane Database Syst Rev
-
-
van Dalen, E.C.1
van der Pal, H.J.2
Caron, H.N.3
Kremer, L.C.4
-
38
-
-
34548299678
-
Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis
-
Wallace KB (2007) Adriamycin-induced interference with cardiac mitochondrial calcium homeostasis. Cardiovasc Toxicol 7:101-107.
-
(2007)
Cardiovasc Toxicol
, vol.7
, pp. 101-107
-
-
Wallace, K.B.1
-
39
-
-
33750282789
-
Deferasirox and deferiprone remove cardiac iron in the iron-overloaded gerbil
-
Wood JC, Otto-Duessel M, Gonzalez I, Aguilar MI, Shimada H, Nick H, Nelson M, and Moats R (2006) Deferasirox and deferiprone remove cardiac iron in the iron-overloaded gerbil. Transl Res 148:272-280.
-
(2006)
Transl Res
, vol.148
, pp. 272-280
-
-
Wood, J.C.1
Otto-Duessel, M.2
Gonzalez, I.3
Aguilar, M.I.4
Shimada, H.5
Nick, H.6
Nelson, M.7
Moats, R.8
-
40
-
-
33644806519
-
Protecting against anthracycline-induced myocardial damage: A review of the most promising strategies
-
Wouters KA, Kremer LC, Miller TL, Herman EH, and Lipshultz SE (2005) Protecting against anthracycline-induced myocardial damage: a review of the most promising strategies. Br J Haematol 131:561-578.
-
(2005)
Br J Haematol
, vol.131
, pp. 561-578
-
-
Wouters, K.A.1
Kremer, L.C.2
Miller, T.L.3
Herman, E.H.4
Lipshultz, S.E.5
-
41
-
-
33748968521
-
Deferiprone protects the isolated atria from cardiotoxicity induced by doxorubicin
-
Xu LJ, Jin L, Pan H, Zhang AZ, Wei G, Li PP, and Lu WY (2006) Deferiprone protects the isolated atria from cardiotoxicity induced by doxorubicin. Acta Pharmacol Sin 27:1333-1339.
-
(2006)
Acta Pharmacol Sin
, vol.27
, pp. 1333-1339
-
-
Xu, L.J.1
Jin, L.2
Pan, H.3
Zhang, A.Z.4
Wei, G.5
Li, P.P.6
Lu, W.Y.7
-
42
-
-
23044447053
-
Molecular pharmacology of the interaction of anthracyclines with iron
-
Xu X, Persson HL, and Richardson DR (2005) Molecular pharmacology of the interaction of anthracyclines with iron. Mol Pharmacol 68:261-271.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 261-271
-
-
Xu, X.1
Persson, H.L.2
Richardson, D.R.3
-
43
-
-
40849085410
-
Iron chelation by clinically relevant anthracyclines: Alteration in expression of iron-regulated genes and atypical changes in intracellular iron distribution and trafficking
-
Xu X, Sutak R, and Richardson DR (2008) Iron chelation by clinically relevant anthracyclines: alteration in expression of iron-regulated genes and atypical changes in intracellular iron distribution and trafficking. Mol Pharmacol 73:833-844.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 833-844
-
-
Xu, X.1
Sutak, R.2
Richardson, D.R.3
-
44
-
-
2442478599
-
Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines
-
Yasumoto E, Nakano K, Nakayachi T, Morshed SR, Hashimoto K, Kikuchi H, Nishikawa H, Kawase M, and Sakagami H (2004) Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines. Anticancer Res 24:755-762.
-
(2004)
Anticancer Res
, vol.24
, pp. 755-762
-
-
Yasumoto, E.1
Nakano, K.2
Nakayachi, T.3
Morshed, S.R.4
Hashimoto, K.5
Kikuchi, H.6
Nishikawa, H.7
Kawase, M.8
Sakagami, H.9
-
45
-
-
0028882170
-
Influence of lipophilicity on the bioavailability and disposition of orally active 3-hydroxypyridin-4-one metal chelators
-
Yokel RA, Fredenburg AM, Meurer KA, and Skinner TL (1995) Influence of lipophilicity on the bioavailability and disposition of orally active 3-hydroxypyridin-4-one metal chelators. Drug Metab Dispos 23:1178-1180.
-
(1995)
Drug Metab Dispos
, vol.23
, pp. 1178-1180
-
-
Yokel, R.A.1
Fredenburg, A.M.2
Meurer, K.A.3
Skinner, T.L.4
-
46
-
-
33845753448
-
Chelators at the cancer coalface: Desferrioxamine to triapine and beyond
-
Yu Y, Wong J, Lovejoy DB, Kalinowski DS, and Richardson DR (2006) Chelators at the cancer coalface: desferrioxamine to triapine and beyond. Clin Cancer Res 12:6876-6883.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6876-6883
-
-
Yu, Y.1
Wong, J.2
Lovejoy, D.B.3
Kalinowski, D.S.4
Richardson, D.R.5
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