-
1
-
-
0026323685
-
Role of oxygen radicals in myocardial reperfusion injury: Experimental and clinical evidence
-
Flaherty, J.T. and Zweier, J.L. (1991). Role of oxygen radicals in myocardial reperfusion injury: experimental and clinical evidence. Klin. Wochenschr. 69:1061-1065.
-
(1991)
Klin. Wochenschr.
, vol.69
, pp. 1061-1065
-
-
Flaherty, J.T.1
Zweier, J.L.2
-
2
-
-
0033067885
-
Iron-mediated cardiovascular injury
-
Horwitz, L.D. and Rosenthal, E.A. (1999). Iron-mediated cardiovascular injury. Vasc. Med. 4:93-99.
-
(1999)
Vasc. Med.
, vol.4
, pp. 93-99
-
-
Horwitz, L.D.1
Rosenthal, E.A.2
-
3
-
-
0024307575
-
Early treatment with deferoxamine limits myocardial ischemic/reperfusion injury
-
Reddy, B.R., Kloner, R.A., and Przyklenk, K. (1989). Early treatment with deferoxamine limits myocardial ischemic/reperfusion injury. Free Radical Biol. Med. 7:45-52.
-
(1989)
Free Radical Biol. Med.
, vol.7
, pp. 45-52
-
-
Reddy, B.R.1
Kloner, R.A.2
Przyklenk, K.3
-
4
-
-
0031906718
-
Chemical, biological and clinical aspects of dexrazoxane and other bisdioxopiperazines
-
Hasinoff, B.B., Hellmann, K., Herman, E.H., and Ferrans, V.J. (1998). Chemical, biological and clinical aspects of dexrazoxane and other bisdioxopiperazines. Curr. Med. Chem. 5:1-28.
-
(1998)
Curr. Med. Chem.
, vol.5
, pp. 1-28
-
-
Hasinoff, B.B.1
Hellmann, K.2
Herman, E.H.3
Ferrans, V.J.4
-
5
-
-
0031706330
-
Chemistry of dexrazoxane and analogues
-
Hasinoff, B.B. (1998). Chemistry of dexrazoxane and analogues. Semin. Oncol. 25(Suppl. 10):3-9.
-
(1998)
Semin. Oncol.
, vol.25
, Issue.10 SUPPL.
, pp. 3-9
-
-
Hasinoff, B.B.1
-
6
-
-
0031714464
-
The role of iron in doxorubicin-induced cardiomyopathy
-
Meyers, C.E. (1998). The role of iron in doxorubicin-induced cardiomyopathy. Semin. Oncol. 25(Suppl. 10): 10-14.
-
(1998)
Semin. Oncol.
, vol.25
, Issue.10 SUPPL.
, pp. 10-14
-
-
Meyers, C.E.1
-
7
-
-
0029114832
-
Production of hydroxyl radical by iron(III)-anthraquinone complexes through self-reduction and through reductive activation by the xanthine oxidase/hypoxanthine system
-
Malisza, K.L. and Hasinoff, B.B. (1995). Production of hydroxyl radical by iron(III)-anthraquinone complexes through self-reduction and through reductive activation by the xanthine oxidase/hypoxanthine system. Arch. Biochem. Biophys. 321:51-60.
-
(1995)
Arch. Biochem. Biophys.
, vol.321
, pp. 51-60
-
-
Malisza, K.L.1
Hasinoff, B.B.2
-
9
-
-
0025324554
-
The hydrolysis-activation of the doxorubicin cardioprotective agent ICRF-187 ((+)-1,2-bis (3,5-dioxopiperazinyl-1-yl)propane)
-
Hasinoff, B.B. (1990). The hydrolysis-activation of the doxorubicin cardioprotective agent ICRF-187 ((+)-1,2-bis (3,5-dioxopiperazinyl-1-yl)propane). Drug Metab. Dispos. 18:344-349.
-
(1990)
Drug Metab. Dispos.
, vol.18
, pp. 344-349
-
-
Hasinoff, B.B.1
-
10
-
-
0028093440
-
Pharmacodynamics of the hydrolysis-activation of the cardioprotective agent (+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane
-
Hasinoff, B.B. (1994). Pharmacodynamics of the hydrolysis-activation of the cardioprotective agent (+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane. J. Pharm. Sci. 83:64-67.
-
(1994)
J. Pharm. Sci.
, vol.83
, pp. 64-67
-
-
Hasinoff, B.B.1
-
11
-
-
0028217545
-
An HPLC and spectrophotometric study of the hydrolysis of ICRF-187 (dexrazoxane, (+)- 1,2-bis(3,5-dioxopiperazinyl-1-yl)propane) and its one-ring opened intermediates
-
Hasinoff, B.B. (1994). An HPLC and spectrophotometric study of the hydrolysis of ICRF-187 (dexrazoxane, (+)- 1,2-bis(3,5-dioxopiperazinyl-1-yl)propane) and its one-ring opened intermediates. Int. J. Pharm. 107:67-76.
-
(1994)
Int. J. Pharm.
, vol.107
, pp. 67-76
-
-
Hasinoff, B.B.1
-
12
-
-
0027740137
-
The one-ring open hydrolysis product intermediates of the cardioprotective agent ICRF-187 (dexrazoxane) displace iron from iron-anthracycline complexes
-
Buss, J.L. and Hasinoff, B.B. (1993). The one-ring open hydrolysis product intermediates of the cardioprotective agent ICRF-187 (dexrazoxane) displace iron from iron-anthracycline complexes. Agents Actions 40:86-95.
-
(1993)
Agents Actions
, vol.40
, pp. 86-95
-
-
Buss, J.L.1
Hasinoff, B.B.2
-
13
-
-
0034136253
-
Iron complexes of the cardioprotective agent dexrazoxane (ICRF-187) and its desmethyl derivative, ICRF-154: Solid state structure, solution thermodynamics, and DNA cleavage activity
-
Diop, N.K., Vitellaro, L.K., Arnold, P., Shang, M., and Marusak, R.A. (2000). Iron complexes of the cardioprotective agent dexrazoxane (ICRF-187) and its desmethyl derivative, ICRF-154: solid state structure, solution thermodynamics, and DNA cleavage activity. J. Inorg. Biochem. 78:209-216.
-
(2000)
J. Inorg. Biochem.
, vol.78
, pp. 209-216
-
-
Diop, N.K.1
Vitellaro, L.K.2
Arnold, P.3
Shang, M.4
Marusak, R.A.5
-
14
-
-
0020398870
-
Metal binding by pharmaceuticals. Part 2. Interactions of Ca(II), Cu(II), Fe(II), Mg(II), Mn(II) and Zn(II) with the intracellular hydrolysis products of the antitumor agent ICRF-159 and its inactive homologue ICRF-192
-
Huang, Z.-X., May, P.M., Quinlan, K.M., Williams, D.R., and Creighton, A.M. (1982). Metal binding by pharmaceuticals. Part 2. Interactions of Ca(II), Cu(II), Fe(II), Mg(II), Mn(II) and Zn(II) with the intracellular hydrolysis products of the antitumor agent ICRF-159 and its inactive homologue ICRF-192. Agents Actions 12:536-542.
-
(1982)
Agents Actions
, vol.12
, pp. 536-542
-
-
Huang, Z.-X.1
May, P.M.2
Quinlan, K.M.3
Williams, D.R.4
Creighton, A.M.5
-
15
-
-
0016775708
-
Studies on the stability and cellular distribution of dioxopiperazines in cultured BHK-21S cells
-
Dawson, K.M. (1975). Studies on the stability and cellular distribution of dioxopiperazines in cultured BHK-21S cells. Biochem. Pharmacol. 24:2249-2253.
-
(1975)
Biochem. Pharmacol.
, vol.24
, pp. 2249-2253
-
-
Dawson, K.M.1
-
16
-
-
0034495569
-
Dexrazoxane-induced reduction in mortality in mice subjected to severe forebrain ischemia
-
Rodriguez, R., Gerson, R., and Santiago-Mejia, J. (2000). Dexrazoxane-induced reduction in mortality in mice subjected to severe forebrain ischemia. Drug Dev. Res. 51: 149-152.
-
(2000)
Drug Dev. Res.
, vol.51
, pp. 149-152
-
-
Rodriguez, R.1
Gerson, R.2
Santiago-Mejia, J.3
-
17
-
-
0028915312
-
Morphologic and morphometric evaluation of the effect of ICRF-187 on bleomycin-induced pulmonary toxicity
-
Herman, E.H., Hasinoff, B.B., Zhang, J., Raley, L.G., Zhang, T.-M., Fukada, Y., et al. (1995). Morphologic and morphometric evaluation of the effect of ICRF-187 on bleomycin-induced pulmonary toxicity. Toxicology 98:163-175.
-
(1995)
Toxicology
, vol.98
, pp. 163-175
-
-
Herman, E.H.1
Hasinoff, B.B.2
Zhang, J.3
Raley, L.G.4
Zhang, T.-M.5
Fukada, Y.6
-
18
-
-
0025677479
-
Ameliorative effects of ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane] on the cardiotoxicity induced by doxorubicin or by isoproterenol in the mouse
-
Flandina, C., Sanguedolce, R., Rausa, L., and D'Alessandro, N. (1990). Ameliorative effects of ICRF-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane] on the cardiotoxicity induced by doxorubicin or by isoproterenol in the mouse. Res. Commun. Chem. Pathol. Pharmacol. 70:259-272.
-
(1990)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.70
, pp. 259-272
-
-
Flandina, C.1
Sanguedolce, R.2
Rausa, L.3
D'Alessandro, N.4
-
19
-
-
0021084131
-
Examination of the protective effect of ICRF-187 and dimethyl sulfoxide against acetaminophen-induced hepatotoxicity in Syrian golden hamsters
-
El-Hage, A.N., Herman, E.H., and Ferrans, V.J. (1983). Examination of the protective effect of ICRF-187 and dimethyl sulfoxide against acetaminophen-induced hepatotoxicity in Syrian golden hamsters. Toxicology 28:295-303.
-
(1983)
Toxicology
, vol.28
, pp. 295-303
-
-
El-Hage, A.N.1
Herman, E.H.2
Ferrans, V.J.3
-
20
-
-
0022573323
-
Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice
-
El-Hage, A., Herman, E.H., Yang, G.C., Crouch, R.K., and Ferrans, V.J. (1986). Mechanism of the protective activity of ICRF-187 against alloxan-induced diabetes in mice. Res. Commun. Chem. Pathol. Pharmacol. 52:341-360.
-
(1986)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.52
, pp. 341-360
-
-
El-Hage, A.1
Herman, E.H.2
Yang, G.C.3
Crouch, R.K.4
Ferrans, V.J.5
-
21
-
-
0026701351
-
Effect of ICRF-187 on the pulmonary damage induced by hyperoxia in the rat
-
Fukuda, Y., Herman, E.H., and Ferrans, V.J. (1992). Effect of ICRF-187 on the pulmonary damage induced by hyperoxia in the rat. Toxicology 74:185-202.
-
(1992)
Toxicology
, vol.74
, pp. 185-202
-
-
Fukuda, Y.1
Herman, E.H.2
Ferrans, V.J.3
-
22
-
-
0034845755
-
Palmitate uptake by neonatal rat myocytes and hepatocytes. Role of extracellular protein
-
Elmadhoun, B.M., Wang, G.Q., Kirshenbaum, L.A., and Burczynski, F.J. (2001). Palmitate uptake by neonatal rat myocytes and hepatocytes. Role of extracellular protein. Eur. J. Biochem. 268:3145-3153.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 3145-3153
-
-
Elmadhoun, B.M.1
Wang, G.Q.2
Kirshenbaum, L.A.3
Burczynski, F.J.4
-
23
-
-
0028121043
-
Reoxygenation-induced cell damage of isolated neonatal rat ventricular myocytes can be reduced by chain-breaking antioxidants
-
Ek, B., Hallberg, C., Sjogren; K.-G., and Hjalmarson, A. (1994). Reoxygenation-induced cell damage of isolated neonatal rat ventricular myocytes can be reduced by chain-breaking antioxidants. Free Radical Biol. Med. 16:117-121.
-
(1994)
Free Radical Biol. Med.
, vol.16
, pp. 117-121
-
-
Ek, B.1
Hallberg, C.2
Sjogren, K.-G.3
Hjalmarson, A.4
-
24
-
-
18344410299
-
Chelation and mobilization of cellular iron by different classes of chelators
-
Zanninelli, G., Glickstein, H., Breuer, W., Milgram, P., Brissot, P., Hider, R.C., et al. (1997). Chelation and mobilization of cellular iron by different classes of chelators. Mol. Pharmacol. 51:842-852.
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 842-852
-
-
Zanninelli, G.1
Glickstein, H.2
Breuer, W.3
Milgram, P.4
Brissot, P.5
Hider, R.C.6
-
25
-
-
0030030821
-
A fluorescence assay for assessing chelation of intracellular iron in a membrane model system and in mammalian cells
-
Cabantchik, Z.I., Glickstein, H., Milgram, P., and Breuer, W. (1996). A fluorescence assay for assessing chelation of intracellular iron in a membrane model system and in mammalian cells. Anal. Biochem. 233:221-227.
-
(1996)
Anal. Biochem.
, vol.233
, pp. 221-227
-
-
Cabantchik, Z.I.1
Glickstein, H.2
Milgram, P.3
Breuer, W.4
-
27
-
-
0027661677
-
Anthracycline cytoxicity is potentiated by iron and inhibited by deferoxamine: Studies in rat heart cells in culture
-
Hershko, C., Link, G., Tzahor, M., Kaltwasser, J.P., Athias, P., Grynberg, A., et al. (1993). Anthracycline cytoxicity is potentiated by iron and inhibited by deferoxamine: studies in rat heart cells in culture. J. Lab. Clin. Med. 122:245-251.
-
(1993)
J. Lab. Clin. Med.
, vol.122
, pp. 245-251
-
-
Hershko, C.1
Link, G.2
Tzahor, M.3
Kaltwasser, J.P.4
Athias, P.5
Grynberg, A.6
-
28
-
-
0021812284
-
Comparison of the protective effect of ICRF-187 and structurally related analogues against acute daunorubicin toxicity in syrian golden hamsters
-
Herman, E.H., El-Hage, A.N., Creighton, A.M., Witiak, D.T., and Ferrans, V.J. (1985). Comparison of the protective effect of ICRF-187 and structurally related analogues against acute daunorubicin toxicity in syrian golden hamsters. Res. Commun. Chem. Pathol. Pharmacol. 48:39-55.
-
(1985)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.48
, pp. 39-55
-
-
Herman, E.H.1
El-Hage, A.N.2
Creighton, A.M.3
Witiak, D.T.4
Ferrans, V.J.5
-
29
-
-
0028959660
-
Ferrous ion strongly promotes the ring opening of the hydrolysis intermediates of the antioxidant doxorubicin cardioprotective agent ICRF-187 (dexrazoxane)
-
Buss, J.L. and Hasinoff, B.B. (1995). Ferrous ion strongly promotes the ring opening of the hydrolysis intermediates of the antioxidant doxorubicin cardioprotective agent ICRF-187 (dexrazoxane). Arch. Biochem. Biophys. 317: 121-127.
-
(1995)
Arch. Biochem. Biophys.
, vol.317
, pp. 121-127
-
-
Buss, J.L.1
Hasinoff, B.B.2
-
30
-
-
0035874476
-
Subcellular distribution of chelatable iron: A laser scanning microscopic study in isolated hepatocytes and liver endothelial cells
-
Petrat, F., de Groot, H., and Rauen, U. (2001). Subcellular distribution of chelatable iron: a laser scanning microscopic study in isolated hepatocytes and liver endothelial cells. Biochem. J. 356:61-69.
-
(2001)
Biochem. J.
, vol.356
, pp. 61-69
-
-
Petrat, F.1
De Groot, H.2
Rauen, U.3
-
31
-
-
0032546922
-
Role of ferritin in the control of the labile iron pool in murine erythroleukemia cells
-
Picard, V., Epsztejn, S., Santambrogio, P., Cabantchik, Z.I., and Beaumont, C. (1998). Role of ferritin in the control of the labile iron pool in murine erythroleukemia cells. J. Biol. Chem. 273:15,382-15,386.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15382-15386
-
-
Picard, V.1
Epsztejn, S.2
Santambrogio, P.3
Cabantchik, Z.I.4
Beaumont, C.5
-
32
-
-
0026496068
-
Pharmacokinetics of the cardioprotector ADR-529 (ICRF-187) in escalating doses combined with fixed-dose doxorubicin
-
Hochster, H., Liebes, L., Wadler, S., Oratz, R., Wernz, J.C., Meyers, M., et al. (1992). Pharmacokinetics of the cardioprotector ADR-529 (ICRF-187) in escalating doses combined with fixed-dose doxorubicin. J. Natl. Cancer Inst. 84:1725-1730.
-
(1992)
J. Natl. Cancer Inst.
, vol.84
, pp. 1725-1730
-
-
Hochster, H.1
Liebes, L.2
Wadler, S.3
Oratz, R.4
Wernz, J.C.5
Meyers, M.6
-
33
-
-
0032951707
-
Determination of the chelatable iron pool of isolated rat hepatocytes by digital fluorescence microscopy using the fluorescent probe, phen green SK
-
Petrat, F., Rauen, U., and de Groot, H. (1999). Determination of the chelatable iron pool of isolated rat hepatocytes by digital fluorescence microscopy using the fluorescent probe, phen green SK. Hepatology 29:1171-1179.
-
(1999)
Hepatology
, vol.29
, pp. 1171-1179
-
-
Petrat, F.1
Rauen, U.2
De Groot, H.3
-
34
-
-
0025607756
-
The effect of desferal on rat heart mitochondrial function, iron content, and xanthine dehydrogenase/oxidase conversion during ischemia-reperfusion
-
van Jaarsveld, H., Potgieter, G.M., Kuyl, J.M., Barnard, H.C., and Barnard, S.P. (1990). The effect of desferal on rat heart mitochondrial function, iron content, and xanthine dehydrogenase/oxidase conversion during ischemia-reperfusion. Clin. Biochem. 23:509-513.
-
(1990)
Clin. Biochem.
, vol.23
, pp. 509-513
-
-
Van Jaarsveld, H.1
Potgieter, G.M.2
Kuyl, J.M.3
Barnard, H.C.4
Barnard, S.P.5
-
35
-
-
0035894070
-
Iron complexes of deferiprone and dietary plant catechols as cytoprotective superoxide radical scavengers
-
Moridani, M.Y. and O'Brien, P.J. (2001). Iron complexes of deferiprone and dietary plant catechols as cytoprotective superoxide radical scavengers. Biochem. Pharmacol. 62: 1579-1585.
-
(2001)
Biochem. Pharmacol.
, vol.62
, pp. 1579-1585
-
-
Moridani, M.Y.1
O'Brien, P.J.2
|