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Volumn 114, Issue 19, 2009, Pages 4009-4013

Deferasirox pharmacokinetics in patients with adequate versus inadequate response

Author keywords

[No Author keywords available]

Indexed keywords

DEFERASIROX; DEFEROXAMINE; FERRITIN;

EID: 77950425913     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-05-222729     Document Type: Article
Times cited : (78)

References (17)
  • 1
    • 20844460608 scopus 로고    scopus 로고
    • Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine
    • Borgna-Pignatti C, Rugolotto S, De Stefano P, et al. Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine. Haematologica. 2004;89(10):1187-1193.
    • (2004) Haematologica , vol.89 , Issue.10 , pp. 1187-1193
    • Borgna-Pignatti, C.1    Rugolotto, S.2    De Stefano, P.3
  • 2
    • 33749991316 scopus 로고    scopus 로고
    • Phase II clinical evaluation of deferasirox, a once-daily oral chelating agent, in pediatric patients with betathalassemia major
    • Galanello R, Piga A, Forni GL, et al. Phase II clinical evaluation of deferasirox, a once-daily oral chelating agent, in pediatric patients with betathalassemia major. Haematologica. 2006;91(10):1343-1351.
    • (2006) Haematologica , vol.91 , Issue.10 , pp. 1343-1351
    • Galanello, R.1    Piga, A.2    Forni, G.L.3
  • 3
    • 33646414765 scopus 로고    scopus 로고
    • A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia
    • Cappellini MD, Cohen A, Piga A, et al. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia. Blood. 2006;107(9):3455-3462.
    • (2006) Blood , vol.107 , Issue.9 , pp. 3455-3462
    • Cappellini, M.D.1    Cohen, A.2    Piga, A.3
  • 4
    • 60749134100 scopus 로고    scopus 로고
    • Deferasirox in MDS patients with transfusion-caused iron overload: A phase-II study
    • Metzgeroth G, Dinter D, Schultheis B, et al. Deferasirox in MDS patients with transfusion-caused iron overload: a phase-II study. Ann Hematol. 2009;88(4):301-310.
    • (2009) Ann Hematol , vol.88 , Issue.4 , pp. 301-310
    • Metzgeroth, G.1    Dinter, D.2    Schultheis, B.3
  • 5
    • 38049151217 scopus 로고    scopus 로고
    • Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): A 1-yr prospective study
    • Porter J, Galanello R, Saglio G, et al. Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study. Eur J Haematol. 2008;80(2):168-176.
    • (2008) Eur J Haematol , vol.80 , Issue.2 , pp. 168-176
    • Porter, J.1    Galanello, R.2    Saglio, G.3
  • 6
    • 10744230223 scopus 로고    scopus 로고
    • Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: A randomised, double-blind, placebo-controlled, dose-escalation trial
    • Nisbet-Brown E, Olivieri NF, Giardina PJ, et al. Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet. 2003;361(9369):1597-1602.
    • (2003) Lancet , vol.361 , Issue.9369 , pp. 1597-1602
    • Nisbet-Brown, E.1    Olivieri, N.F.2    Giardina, P.J.3
  • 7
    • 38349157810 scopus 로고    scopus 로고
    • Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major
    • Cohen AR, Glimm E, Porter JB. Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major. Blood. 2008;111(2):583-587.
    • (2008) Blood , vol.111 , Issue.2 , pp. 583-587
    • Cohen, A.R.1    Glimm, E.2    Porter, J.B.3
  • 8
    • 33646391919 scopus 로고    scopus 로고
    • Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: New data, new questions
    • Neufeld EJ. Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, new questions. Blood. 2006;107(9):3436-3441.
    • (2006) Blood , vol.107 , Issue.9 , pp. 3436-3441
    • Neufeld, E.J.1
  • 9
    • 0025108768 scopus 로고
    • Treatment of Cooley's anemia
    • Fosburg MT, Nathan DG. Treatment of Cooley's anemia. Blood. 1990;76(3):435-444.
    • (1990) Blood , vol.76 , Issue.3 , pp. 435-444
    • Fosburg, M.T.1    Nathan, D.G.2
  • 10
    • 0014528748 scopus 로고
    • A new method for serum iron and total iron-binding capacity by atomic absorption spectrophotometry
    • Olson AD, Hamlin WB. A new method for serum iron and total iron-binding capacity by atomic absorption spectrophotometry. Clin Chem. 1969;15(6):438-444.
    • (1969) Clin Chem , vol.15 , Issue.6 , pp. 438-444
    • Olson, A.D.1    Hamlin, W.B.2
  • 11
    • 0035810733 scopus 로고    scopus 로고
    • Determination of a new oral iron chelator, ICL670, and its iron complex in plasma by high-performance liquid chromatography and ultraviolet detection
    • Rouan MC, Marfil F, Mangoni P, Sechaud R, Humbert H, Maurer G. Determination of a new oral iron chelator, ICL670, and its iron complex in plasma by high-performance liquid chromatography and ultraviolet detection. J Chromatogr B Biomed Sci Appl. 2001;755(1-2):203-213.
    • (2001) J Chromatogr B Biomed Sci Appl , vol.755 , Issue.1-2 , pp. 203-213
    • Rouan, M.C.1    Marfil, F.2    Mangoni, P.3    Sechaud, R.4    Humbert, H.5    Maurer, G.6
  • 12
    • 47549099814 scopus 로고    scopus 로고
    • Absolute oral bioavailability and disposition of deferasirox in healthy human subjects
    • Séchaud R, Robeva A, Belleli R, Balez S. Absolute oral bioavailability and disposition of deferasirox in healthy human subjects. J Clin Pharmacol. 2008;48(8):919-925.
    • (2008) J Clin Pharmacol , vol.48 , Issue.8 , pp. 919-925
    • Séchaud, R.1    Robeva, A.2    Belleli, R.3    Balez, S.4
  • 13
    • 0026588576 scopus 로고
    • Phase III multi-center clinical study on 99mTc-GSA, a new agent for functional imaging of the liver
    • Torizuka K, Ha-Kawa SK, Kudo M, et al. [Phase III multi-center clinical study on 99mTc-GSA, a new agent for functional imaging of the liver]. Kaku Igaku. 1992;29(2):159-181.
    • (1992) Kaku Igaku , vol.29 , Issue.2 , pp. 159-181
    • Torizuka, K.1    Ha-Kawa, S.K.2    Kudo, M.3
  • 14
    • 0035543925 scopus 로고    scopus 로고
    • Hb Dartmouth [alpha66(E15)Leu→Pro (alpha2) (CTG→CCG)]: A novel alpha2-globin gene mutation associated with severe neonatal anemia when inherited in trans with Southeast Asian alpha-thalassemia-1
    • McBride KL, Snow K, Kubik KS, et al. Hb Dartmouth [alpha66(E15) Leu→Pro (alpha2) (CTG→CCG)]: a novel alpha2-globin gene mutation associated with severe neonatal anemia when inherited in trans with Southeast Asian alpha-thalassemia-1. Hemoglobin. 2001;25(4):375-382.
    • (2001) Hemoglobin , vol.25 , Issue.4 , pp. 375-382
    • McBride, K.L.1    Snow, K.2    Kubik, K.S.3
  • 15
    • 46749120546 scopus 로고    scopus 로고
    • Use of tc-99m mebrofenin as a clinical probe to assess altered hepatobiliary transport: Integration of in vitro, pharmacokinetic modeling, and simulation studies
    • Ghibellini G, Leslie EM, Pollack GM, Brouwer KL. Use of tc-99m mebrofenin as a clinical probe to assess altered hepatobiliary transport: integration of in vitro, pharmacokinetic modeling, and simulation studies. Pharm Res. 2008;25(8):1851-1860.
    • (2008) Pharm Res , vol.25 , Issue.8 , pp. 1851-1860
    • Ghibellini, G.1    Leslie, E.M.2    Pollack, G.M.3    Brouwer, K.L.4
  • 16
    • 39049093099 scopus 로고    scopus 로고
    • Relative bioavailability of deferasirox tablets administered without dispersion and dispersed in various drinks
    • Séchaud R, Dutreix C, Balez S, et al. Relative bioavailability of deferasirox tablets administered without dispersion and dispersed in various drinks. Int J Clin Pharmacol Ther. 2008;46(2):102-108.
    • (2008) Int J Clin Pharmacol Ther , vol.46 , Issue.2 , pp. 102-108
    • Séchaud, R.1    Dutreix, C.2    Balez, S.3
  • 17
    • 73149115676 scopus 로고    scopus 로고
    • Deferasirox (Exjade®) monotherapy significantly reduces cardiac iron burden in chronically transfused β-thalassemia patients: An MRI T2* study
    • Abstract 3882
    • Wood J, Thompson AA, Paley C, et al. Deferasirox (Exjade®) monotherapy significantly reduces cardiac iron burden in chronically transfused β-thalassemia patients: an MRI T2* study. Blood (ASH Annual Meeting Abstracts). 2008; 112:Abstract 3882.
    • (2008) Blood (ASH Annual Meeting Abstracts) , vol.112
    • Wood, J.1    Thompson, A.A.2    Paley, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.