Selective protection by stably transfected human ALDH3A1 (but not human ALDH1A1) against toxicity of aliphatic aldehydes in V79 cells

Chemico-Biological Interactions

Volumn 130-132, Issue , 2001, Pages 261-273

  Townsend, Alan J ^a   Leone Kabler, Sandra ^a   Haynes, Robin L ^a   Wu, Yinghui ^a   Szweda, Luke ^b   Bunting, Kevin D ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chemoprevention; Detoxification; Human ALDH3; Hydroxyalkenals; Lipid aldehydes

Indexed keywords

2 NONENAL; 2 OCTENAL; 4 HYDROXYNONENAL; ACETALDEHYDE; ACROLEIN; ALDEHYDE; ALDEHYDE DEHYDROGENASE; ALDEHYDE DEHYDROGENASE ISOENZYME 1A1; ALDEHYDE DEHYDROGENASE ISOENZYME 3A1; BENZALDEHYDE; CHLOROACETALDEHYDE; FUNCTIONAL GROUP; GLUTATHIONE; HEXANAL; HEXOBARBITAL; MALONALDEHYDE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; APOPTOSIS; CELL PROTECTION; CELL STRAIN V 79; CONFERENCE PAPER; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; DETOXIFICATION; ENZYME SUBSTRATE; GENETIC TRANSFECTION; GROWTH INHIBITION; HUMAN; LIPID PEROXIDATION; MACROPHAGE; MOUSE; NONHUMAN; OXIDATION; STRUCTURE ACTIVITY RELATION; TRANSGENE;

ACETALDEHYDE; ACROLEIN; ALDEHYDE DEHYDROGENASE; ALDEHYDES; ALKYLATION; ANIMALS; APOPTOSIS; BENZALDEHYDES; CELL DIVISION; CELL LINE; CRICETINAE; DRUG RESISTANCE; HUMANS; ISOENZYMES; LIPID PEROXIDATION; METABOLIC DETOXICATION, DRUG; PROTEINS; RATS; TRANSFECTION;

MURINAE;

EID: 0035969833     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(00)00270-2     Document Type: Conference Paper

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