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Volumn 2011, Issue , 2011, Pages

The bone niche of chondrosarcoma: A sanctuary for drug resistance, tumour growth and also a source of new therapeutic targets

Author keywords

[No Author keywords available]

Indexed keywords

ADAMTS1 PROTEIN; ANTINEOPLASTIC AGENT; BISPHOSPHONIC ACID DERIVATIVE; CELECOXIB; CHEMOKINE RECEPTOR CXCR4; CYCLOPHOSPHAMIDE; ENDOSTATIN; HISTONE DEACETYLASE 4; HYPOXIA INDUCIBLE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MAMMALIAN TARGET OF RAPAMYCIN; ONCOSTATIN M; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPONTIN; RANTES; STROMAL CELL DERIVED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; ZOLEDRONIC ACID;

EID: 80052668046     PISSN: 1357714X     EISSN: 13691643     Source Type: Journal    
DOI: 10.1155/2011/932451     Document Type: Review
Times cited : (58)

References (85)
  • 1
    • 53149144278 scopus 로고    scopus 로고
    • A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcoma
    • Boeuf S., Kunz P., Hennig T., Lehner B., Hogendoorn P. C. W., Bovée J. V. M. G., Richter W., A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcoma Journal of Pathology 2008 216 2 158 166
    • (2008) Journal of Pathology , vol.216 , Issue.2 , pp. 158-166
    • Boeuf, S.1    Kunz, P.2    Hennig, T.3    Lehner, B.4    Hogendoorn, P.C.W.5    Bovée, J.V.M.G.6    Richter, W.7
  • 2
    • 22944487703 scopus 로고    scopus 로고
    • Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment
    • DOI 10.1016/S1470-2045(05)70282-5, PII S1470204505702825
    • Bovée J. V. M. G., Cleton-Jansen A. M., Taminiau A. H. M., Hogendoorn P. C. W., Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment Lancet Oncology 2005 6 8 599 607 (Pubitemid 41051938)
    • (2005) Lancet Oncology , vol.6 , Issue.8 , pp. 599-607
    • Bovee, J.V.M.G.1    Cleton-Jansen, A.-M.2    Taminiau, A.H.M.3    Hogendoorn, P.C.W.4
  • 3
    • 0036380586 scopus 로고    scopus 로고
    • Towards a new understanding and classification of chondrogenic neoplasias of the skeletonbiochemistry and cell biology of chondrosarcoma and its variants
    • Aigner T., Towards a new understanding and classification of chondrogenic neoplasias of the skeletonbiochemistry and cell biology of chondrosarcoma and its variants Virchows Archiv 2002 441 3 219 230
    • (2002) Virchows Archiv , vol.441 , Issue.3 , pp. 219-230
    • Aigner, T.1
  • 5
    • 80052676155 scopus 로고    scopus 로고
    • Recent advances in the biology of bone tumors and new diagnostic tools
    • chapter 19 New York, NY, USA Academic Press
    • De Pinieux G., Bouvier C., Heymann D., Recent advances in the biology of bone tumors and new diagnostic tools Bone Cancer 2010 chapter 19 New York, NY, USA Academic Press 225 234
    • (2010) Bone Cancer , pp. 225-234
    • De Pinieux, G.1    Bouvier, C.2    Heymann, D.3
  • 7
    • 52049103847 scopus 로고    scopus 로고
    • The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance
    • Meads M. B., Hazlehurst L. A., Dalton W. S., The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance Clinical Cancer Research 2008 14 9 2519 2526
    • (2008) Clinical Cancer Research , vol.14 , Issue.9 , pp. 2519-2526
    • Meads, M.B.1    Hazlehurst, L.A.2    Dalton, W.S.3
  • 10
    • 80052657175 scopus 로고    scopus 로고
    • Non-surgical treatment of chondrosarcoma: Current concepts and future perspectives
    • chapter 31 New York, NY, USA Academic Press
    • Staals E.L., Palmerini E., Ferrari S., Mercuri M., Heymann D., Non-surgical treatment of chondrosarcoma: current concepts and future perspectives Bone Cancer 2010 chapter 31 New York, NY, USA Academic Press 375 383
    • (2010) Bone Cancer , pp. 375-383
    • Staals, E.L.1    Palmerini, E.2    Ferrari, S.3    Mercuri, M.4    Heymann, D.5
  • 13
    • 3242669145 scopus 로고    scopus 로고
    • Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche
    • DOI 10.1016/j.cell.2004.07.004, PII S0092867404006622
    • Arai F., Hirao A., Ohmura M., Sato H., Matsuoka S., Takubo K., Ito K., Koh G. Y., Suda T., Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche Cell 2004 118 2 149 161 (Pubitemid 38962572)
    • (2004) Cell , vol.118 , Issue.2 , pp. 149-161
    • Arai, F.1    Hirao, A.2    Ohmura, M.3    Sato, H.4    Matsuoka, S.5    Takubo, K.6    Ito, K.7    Koh, G.Y.8    Suda, T.9
  • 14
    • 0035871882 scopus 로고    scopus 로고
    • Spatial localization of transplanted hemopoietic stem cells: Inferences for the localization of stem cell niches
    • DOI 10.1182/blood.V97.8.2293
    • Nilsson S. K., Johnston H. M., Coverdale J. A., Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches Blood 2001 97 8 2293 2299 (Pubitemid 32291474)
    • (2001) Blood , vol.97 , Issue.8 , pp. 2293-2299
    • Nilsson, S.K.1    Johnston, H.M.2    Coverdale, J.A.3
  • 15
    • 67449092765 scopus 로고    scopus 로고
    • Cancer stem cells and their niche
    • Iwasaki H., Suda T., Cancer stem cells and their niche Cancer Science 2009 100 7 1166 1172
    • (2009) Cancer Science , vol.100 , Issue.7 , pp. 1166-1172
    • Iwasaki, H.1    Suda, T.2
  • 17
    • 69849104865 scopus 로고    scopus 로고
    • The leukemic stem cell niche: Current concepts and therapeutic opportunities
    • Lane S. W., Scadden D. T., Gilliland D. G., The leukemic stem cell niche: current concepts and therapeutic opportunities Blood 2009 114 6 1150 1157
    • (2009) Blood , vol.114 , Issue.6 , pp. 1150-1157
    • Lane, S.W.1    Scadden, D.T.2    Gilliland, D.G.3
  • 22
    • 50549121134 scopus 로고
    • The distribution of secondary growths in cancer of the breast
    • Paget S., The distribution of secondary growths in cancer of the breast The Lancet 1889 133 3421 571 573
    • (1889) The Lancet , vol.133 , Issue.3421 , pp. 571-573
    • Paget, S.1
  • 24
    • 77956038665 scopus 로고    scopus 로고
    • Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells
    • Hosokawa K., Arai F., Yoshihara H., Iwasaki H., Nakamura Y., Gomei Y., Suda T., Knockdown of N-cadherin suppresses the long-term engraftment of hematopoietic stem cells Blood 2010 116 4 554 563
    • (2010) Blood , vol.116 , Issue.4 , pp. 554-563
    • Hosokawa, K.1    Arai, F.2    Yoshihara, H.3    Iwasaki, H.4    Nakamura, Y.5    Gomei, Y.6    Suda, T.7
  • 25
    • 80052689884 scopus 로고    scopus 로고
    • Early bone metastasis-associated molecular and cellular events
    • chapter 3 New York, NY, USA Academic Press
    • Clézardin P., Heymann D., Early bone metastasis-associated molecular and cellular events Bone Cancer 2010 chapter 3 New York, NY, USA Academic Press 41 45
    • (2010) Bone Cancer , pp. 41-45
    • Clézardin, P.1    Heymann, D.2
  • 26
    • 77955497101 scopus 로고    scopus 로고
    • Current and emerging concepts in tumour metastasis
    • Coghlin C., Murray G. I., Current and emerging concepts in tumour metastasis Journal of Pathology 2010 222 1 1 15
    • (2010) Journal of Pathology , vol.222 , Issue.1 , pp. 1-15
    • Coghlin, C.1    Murray, G.I.2
  • 29
    • 36549069842 scopus 로고    scopus 로고
    • Tumor dormancy and surgery-driven interruption of dormancy in breast cancer: Learning from failures
    • DOI 10.1038/ncponc0999, PII NCPONC0999
    • Demicheli R., Retsky M. W., Hrushesky W. J. M., Baum M., Tumor dormancy and surgery-driven interruption of dormancy in breast cancer: learning from failures Nature Clinical Practice Oncology 2007 4 12 699 710 (Pubitemid 350187005)
    • (2007) Nature Clinical Practice Oncology , vol.4 , Issue.12 , pp. 699-710
    • Demicheli, R.1    Retsky, M.W.2    Hrushesky, W.J.M.3    Baum, M.4
  • 31
    • 0036788701 scopus 로고    scopus 로고
    • Bone remodelling and tumour grade modifications induced by interactions between bone and Swarm rat chondrosarcoma
    • Grimaud E., Damiens C., Rousselle A. V., Passuti N., Heymann D., Gouin F., Bone remodelling and tumour grade modifications induced by interactions between bone and Swarm rat chondrosarcoma Histology and Histopathology 2002 17 4 1103 1111
    • (2002) Histology and Histopathology , vol.17 , Issue.4 , pp. 1103-1111
    • Grimaud, E.1    Damiens, C.2    Rousselle, A.V.3    Passuti, N.4    Heymann, D.5    Gouin, F.6
  • 32
    • 0029174654 scopus 로고
    • The periosteum: The umbilical cord of bone. Quantification of the blood supply of cortical bone of periosteal origin
    • Chanavaz M., The periosteum: the umbilical cord of bone. Quantification of the blood supply of cortical bone of periosteal origin Revue de Stomatologie et de Chirurgie Maxillo-Faciale 1995 96 4 262 267
    • (1995) Revue de Stomatologie et de Chirurgie Maxillo-Faciale , vol.96 , Issue.4 , pp. 262-267
    • Chanavaz, M.1
  • 33
    • 0025013981 scopus 로고
    • Ultrastructure of the periosteum from membrane bone
    • Squier C. A., Ghoneim S., Kremenak C. R., Ultrastructure of the periosteum from membrane bone Journal of Anatomy 1990 171 233 239 (Pubitemid 20341330)
    • (1990) Journal of Anatomy , vol.171 , pp. 233-239
    • Squier, C.A.1    Ghoneim, S.2    Kremenak, C.R.3
  • 35
  • 36
    • 53149144278 scopus 로고    scopus 로고
    • A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcoma
    • Boeuf S., Kunz P., Hennig T., Lehner B., Hogendoorn P. C. W., Bovée J. V. M. G., Richter W., A chondrogenic gene expression signature in mesenchymal stem cells is a classifier of conventional central chondrosarcoma Journal of Pathology 2008 216 2 158 166
    • (2008) Journal of Pathology , vol.216 , Issue.2 , pp. 158-166
    • Boeuf, S.1    Kunz, P.2    Hennig, T.3    Lehner, B.4    Hogendoorn, P.C.W.5    Bovée, J.V.M.G.6    Richter, W.7
  • 42
    • 41149125007 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1α and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours
    • DOI 10.1302/0301-620X.90B3.19806
    • Kubo T., Sugita T., Shimose S., Matsuo T., Arihiro K., Ochi M., Expression of hypoxia-inducible factor-1 and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours Journal of Bone and Joint Surgery. Series B 2008 90 3 364 370 (Pubitemid 351428956)
    • (2008) Journal of Bone and Joint Surgery - Series B , vol.90 , Issue.3 , pp. 364-370
    • Kubo, T.1    Sugita, T.2    Shimose, S.3    Matsuo, T.4    Arihiro, K.5    Ochi, M.6
  • 43
    • 4844228509 scopus 로고    scopus 로고
    • Hypoxia induces HIF-1α and VEGF expression in chondrosarcoma cells and chondrocytes
    • DOI 10.1016/j.orthres.2004.03.002, PII S0736026604000634
    • Lin C., McGough R., Aswad B., Block J. A., Terek R., Hypoxia induces HIF-1 and VEGF expression in chondrosarcoma cells and chondrocytes Journal of Orthopaedic Research 2004 22 6 1175 1181 (Pubitemid 39317905)
    • (2004) Journal of Orthopaedic Research , vol.22 , Issue.6 , pp. 1175-1181
    • Lin, C.1    McGough, R.2    Aswad, B.3    Block, J.A.4    Terek, R.5
  • 44
    • 0034062753 scopus 로고    scopus 로고
    • Microvasculature and VEGF expression in cartilaginous tumors
    • Ayala G., Liu C., Nicosia R., Horowitz S., Lackman R., Microvasculature and VEGF expression in cartilaginous tumors Human Pathology 2000 31 3 341 346 (Pubitemid 30161353)
    • (2000) Human Pathology , vol.31 , Issue.3 , pp. 341-346
    • Ayala, G.1    Liu, C.2    Nicosia, R.3    Horowitz, S.4    Lackman, R.5
  • 46
    • 0037137897 scopus 로고    scopus 로고
    • Human chondrosarcoma secretes vascular endothelial growth factor to induce tumor angiogenesis and stores basic fibroblast growth factor for regulation of its own growth
    • DOI 10.1002/ijc.1607
    • Furumatsu T., Nishida K., Kawai A., Namba M., Inoue H., Ninomiya Y., Human chondrosarcoma secretes vascular endothelial growth factor to induce tumor angiogenesis and stores basic fibroblast growth factor for regulation of its own growth International Journal of Cancer 2002 97 3 313 322 (Pubitemid 34049021)
    • (2002) International Journal of Cancer , vol.97 , Issue.3 , pp. 313-322
    • Furumatsu, T.1    Nishida, K.2    Kawai, A.3    Namba, M.4    Inoue, H.5    Ninomiya, Y.6
  • 48
    • 77950477521 scopus 로고    scopus 로고
    • Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours
    • Boeuf S., Bovée J. V. M. G., Lehner B., Hogendoorn P. C. W., Richter W., Correlation of hypoxic signalling to histological grade and outcome in cartilage tumours Histopathology 2010 56 5 641 651
    • (2010) Histopathology , vol.56 , Issue.5 , pp. 641-651
    • Boeuf, S.1    Bovée, J.V.M.G.2    Lehner, B.3    Hogendoorn, P.C.W.4    Richter, W.5
  • 50
    • 24344436325 scopus 로고    scopus 로고
    • Diverse signaling pathways through the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesis
    • DOI 10.1016/j.cellsig.2005.03.022, PII S0898656805000677
    • Wang J., Wang J., Sun Y., Song W., Nor J. E., Wang C. Y., Taichman R. S., Diverse signaling pathways through the SDF-1/CXCR4 chemokine axis in prostate cancer cell lines leads to altered patterns of cytokine secretion and angiogenesis Cellular Signalling 2005 17 12 1578 1592 (Pubitemid 41253997)
    • (2005) Cellular Signalling , vol.17 , Issue.12 , pp. 1578-1592
    • Wang, J.1    Wang, J.2    Sun, Y.3    Song, W.4    Nor, J.E.5    Wang, C.Y.6    Taichman, R.S.7
  • 52
    • 77349122362 scopus 로고    scopus 로고
    • CXCR4/SDF1 mediate hypoxia induced chondrosarcoma cell invasion through ERK signaling and increased MMP1 expression
    • Sun X., Wei L., Chen Q., Terek R. M., CXCR4/SDF1 mediate hypoxia induced chondrosarcoma cell invasion through ERK signaling and increased MMP1 expression Molecular Cancer 2010 9, article no. 17
    • (2010) Molecular Cancer , vol.917
    • Sun, X.1    Wei, L.2    Chen, Q.3    Terek, R.M.4
  • 53
    • 58149243217 scopus 로고    scopus 로고
    • Stromal cell-derived factor-1 increase v 3 integrin expression and invasion in human chondrosarcoma cells
    • Lai T. H., Fong Y. C., Fu W. M., Yang R. S., Tang C. H., Stromal cell-derived factor-1 increase v 3 integrin expression and invasion in human chondrosarcoma cells Journal of Cellular Physiology 2009 218 2 334 342
    • (2009) Journal of Cellular Physiology , vol.218 , Issue.2 , pp. 334-342
    • Lai, T.H.1    Fong, Y.C.2    Fu, W.M.3    Yang, R.S.4    Tang, C.H.5
  • 54
    • 71749105656 scopus 로고    scopus 로고
    • Involvement of matrix metalloproteinase-3 in CCL5/CCR5 pathway of chondrosarcomas metastasis
    • Tang C. H., Yamamoto A., Lin Y. T., Fong YI. C., Tan T. W., Involvement of matrix metalloproteinase-3 in CCL5/CCR5 pathway of chondrosarcomas metastasis Biochemical Pharmacology 2010 79 2 209 217
    • (2010) Biochemical Pharmacology , vol.79 , Issue.2 , pp. 209-217
    • Tang, C.H.1    Yamamoto, A.2    Lin, Y.T.3    Fong, Y.I.C.4    Tan, T.W.5
  • 56
    • 77956011271 scopus 로고    scopus 로고
    • Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment
    • Reichert J. C., Quent V. M. C., Burke L. J., Stansfield S. H., Clements J. A., Hutmacher D. W., Mineralized human primary osteoblast matrices as a model system to analyse interactions of prostate cancer cells with the bone microenvironment Biomaterials 2010 31 31 7928 7936
    • (2010) Biomaterials , vol.31 , Issue.31 , pp. 7928-7936
    • Reichert, J.C.1    Quent, V.M.C.2    Burke, L.J.3    Stansfield, S.H.4    Clements, J.A.5    Hutmacher, D.W.6
  • 57
    • 69249235848 scopus 로고    scopus 로고
    • Osteopontin increases migration and MMP-9 up-regulation via v 3 integrin, FAK, ERK, and NF- B-dependent pathway in human chondrosarcoma cells
    • Chen Y. J., Wei Y. Y., Chen H. T., Fong YI. C., Hsu C. J., Tsai C. H., Hsu H. C., Liu S. H., Tang C. H., Osteopontin increases migration and MMP-9 up-regulation via v 3 integrin, FAK, ERK, and NF- B-dependent pathway in human chondrosarcoma cells Journal of Cellular Physiology 2009 221 1 98 108
    • (2009) Journal of Cellular Physiology , vol.221 , Issue.1 , pp. 98-108
    • Chen, Y.J.1    Wei, Y.Y.2    Chen, H.T.3    Fong, Y.I.C.4    Hsu, C.J.5    Tsai, C.H.6    Hsu, H.C.7    Liu, S.H.8    Tang, C.H.9
  • 60
    • 0242361563 scopus 로고    scopus 로고
    • Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: Correlations with local tumor extent and prognosis
    • DOI 10.1002/jso.10305
    • Rutkowski P., Kamiska J., Kowalska M., Ruka W., Steffen J., Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis Journal of Surgical Oncology 2003 84 3 151 159 (Pubitemid 37363158)
    • (2003) Journal of Surgical Oncology , vol.84 , Issue.3 , pp. 151-159
    • Rutkowski, P.1    Kaminska, J.2    Kowalska, M.3    Ruka, W.4    Steffen, J.5
  • 61
    • 33845289447 scopus 로고    scopus 로고
    • ADAMTS1 is regulated by interleukin-1β, not by hypoxia, in chondrosarcoma
    • DOI 10.1016/j.humpath.2006.06.012, PII S0046817706003790
    • Kalinski T., Krueger S., Sel S., Werner K., Rpke M., Roessner A., ADAMTS1 is regulated by interleukin-1, not by hypoxia, in chondrosarcoma Human Pathology 2007 38 1 86 94 (Pubitemid 44880204)
    • (2007) Human Pathology , vol.38 , Issue.1 , pp. 86-94
    • Kalinski, T.1    Krueger, S.2    Sel, S.3    Werner, K.4    Ropke, M.5    Roessner, A.6
  • 62
    • 0034748677 scopus 로고    scopus 로고
    • Human macrophage metalloelastase (MMP-12) expression is induced in chondrocytes during fetal development and malignant transformation
    • DOI 10.1016/S8756-3282(01)00595-6, PII S8756328201005956
    • Kerkel E., Bhling T., Herva R., Uria J. A., Saarialho-Kere U., Human macrophage metalloelastase (MMP-12) expression is induced in chondrocytes during fetal development and malignant transformation Bone 2001 29 5 487 493 (Pubitemid 33026470)
    • (2001) Bone , vol.29 , Issue.5 , pp. 487-493
    • KerkelA, E.1    Bohling, T.2    Herva, R.3    Uria, J.A.4    Saarialho-Kere, U.5
  • 63
    • 38349161595 scopus 로고    scopus 로고
    • -MSH inhibits TNF- -induced matrix metalloproteinase-13 expression by modulating p38 kinase and nuclear factor B signaling in human chondrosarcoma HTB-94 cells
    • Yoon S. W., Chun J. S., Sung M. H., Kim J. Y., Poo H., -MSH inhibits TNF- -induced matrix metalloproteinase-13 expression by modulating p38 kinase and nuclear factor B signaling in human chondrosarcoma HTB-94 cells Osteoarthritis and Cartilage 2008 16 1 115 124
    • (2008) Osteoarthritis and Cartilage , vol.16 , Issue.1 , pp. 115-124
    • Yoon, S.W.1    Chun, J.S.2    Sung, M.H.3    Kim, J.Y.4    Poo, H.5
  • 64
    • 39749170615 scopus 로고    scopus 로고
    • TGF- 1 increases motility and v 3 integrin up-regulation via PI3K, Akt and NF- B-dependent pathway in human chondrosarcoma cells
    • Yeh Y. Y., Chiao C. C., Kuo W. Y., Hsiao YU. C., Chen Y. J., Wei Y. Y., Lai T. H., Fong YI. C., Tang C. H., TGF- 1 increases motility and v 3 integrin up-regulation via PI3K, Akt and NF- B-dependent pathway in human chondrosarcoma cells Biochemical Pharmacology 2008 75 6 1292 1301
    • (2008) Biochemical Pharmacology , vol.75 , Issue.6 , pp. 1292-1301
    • Yeh, Y.Y.1    Chiao, C.C.2    Kuo, W.Y.3    Hsiao, Y.U.C.4    Chen, Y.J.5    Wei, Y.Y.6    Lai, T.H.7    Fong, Y.I.C.8    Tang, C.H.9
  • 67
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce J. A., Pollard J. W., Microenvironmental regulation of metastasis Nature Reviews Cancer 2009 9 4 239 252
    • (2009) Nature Reviews Cancer , vol.9 , Issue.4 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 68
    • 52049103847 scopus 로고    scopus 로고
    • The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance
    • Meads M. B., Hazlehurst L. A., Dalton W. S., The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance Clinical Cancer Research 2008 14 9 2519 2526
    • (2008) Clinical Cancer Research , vol.14 , Issue.9 , pp. 2519-2526
    • Meads, M.B.1    Hazlehurst, L.A.2    Dalton, W.S.3
  • 69
    • 70349735988 scopus 로고    scopus 로고
    • Therapeutic targeting of microenvironmental interactions in leukemia: Mechanisms and approaches
    • Konopleva M., Tabe Y., Zeng Z., Andreeff M., Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches Drug Resistance Updates 2009 12 4-5 103 113
    • (2009) Drug Resistance Updates , vol.12 , Issue.45 , pp. 103-113
    • Konopleva, M.1    Tabe, Y.2    Zeng, Z.3    Andreeff, M.4
  • 72
    • 3042638497 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in chondrosarcoma
    • DOI 10.1159/000078327
    • Sutton K. M., Wright M., Fondren G., Towle C. A., Mankin H. J., Cyclooxygenase-2 expression in chondrosarcoma Oncology 2004 66 4 275 280 (Pubitemid 38822796)
    • (2004) Oncology , vol.66 , Issue.4 , pp. 275-280
    • Sutton, K.M.1    Wright, M.2    Fondren, G.3    Towle, C.A.4    Mankin, H.J.5
  • 74
    • 69249155244 scopus 로고    scopus 로고
    • HDAC4 represses vascular endothelial growth factor expression in chondrosarcoma by modulating RUNX2 activity
    • Sun X., Wei L., Chen Q., Terek R. M., HDAC4 represses vascular endothelial growth factor expression in chondrosarcoma by modulating RUNX2 activity Journal of Biological Chemistry 2009 284 33 21881 21890
    • (2009) Journal of Biological Chemistry , vol.284 , Issue.33 , pp. 21881-21890
    • Sun, X.1    Wei, L.2    Chen, Q.3    Terek, R.M.4
  • 75
    • 13544265432 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: New drugs for the treatment of inflammatory diseases?
    • DOI 10.1016/S1359-6446(04)03309-4, PII S1359644604033094
    • Blanchard F., Chipoy C., Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases? Drug Discovery Today 2005 10 3 197 204 (Pubitemid 40222231)
    • (2005) Drug Discovery Today , vol.10 , Issue.3 , pp. 197-204
    • Blanchard, F.1    Chipoy, C.2
  • 77
    • 34250197914 scopus 로고    scopus 로고
    • MTOR inhibitors (Rapamycin and its derivatives) and nitrogen containing bisphosphonates: Bi-functional compounds for the treatment of bone tumours
    • DOI 10.2174/092986707780831159
    • Ory B., Moriceau G., Redini F., Heymann D., mTOR inhibitors (Rapamycin and its derivatives) and nitrogen containing bisphosphonates: bi-functional compounds for the treatment of bone tumours Current Medicinal Chemistry 2007 14 13 1381 1387 (Pubitemid 46902220)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.13 , pp. 1381-1387
    • Ory, B.1    Moriceau, G.2    Redini, F.3    Heymann, D.4
  • 78
    • 3042796964 scopus 로고    scopus 로고
    • Bisphosphonates: New therapeutic agents for the treatment of bone tumors
    • DOI 10.1016/j.molmed.2004.05.007, PII S1471491404001297
    • Heymann D., Ory B., Gouin F., Green J. R., Rédini F., Bisphosphonates: new therapeutic agents for the treatment of bone tumors Trends in Molecular Medicine 2004 10 7 337 343 (Pubitemid 38881523)
    • (2004) Trends in Molecular Medicine , vol.10 , Issue.7 , pp. 337-343
    • Heymann, D.1    Ory, B.2    Gouin, F.3    Green, J.R.4    Redini, F.5
  • 79
    • 11144257061 scopus 로고    scopus 로고
    • Brief communication: Morphoproteomic portrait of the mTOR pathway in mesenchymal chondrosarcoma
    • Brown R. E., Brief communication: morphoproteomic portrait of the mTOR pathway in mesenchymal chondrosarcoma Annals of Clinical and Laboratory Science 2004 34 4 397 399 (Pubitemid 40040959)
    • (2004) Annals of Clinical and Laboratory Science , vol.34 , Issue.4 , pp. 397-399
    • Brown, R.E.1
  • 81
    • 54249130444 scopus 로고    scopus 로고
    • Targeting the mammalian target of rapamycin in myxoid chondrosarcoma
    • Merimsky O., Bernstein-Molho R., Sagi-Eisenberg R., Targeting the mammalian target of rapamycin in myxoid chondrosarcoma Anti-Cancer Drugs 2008 19 10 1019 1021
    • (2008) Anti-Cancer Drugs , vol.19 , Issue.10 , pp. 1019-1021
    • Merimsky, O.1    Bernstein-Molho, R.2    Sagi-Eisenberg, R.3
  • 84
    • 33745011910 scopus 로고    scopus 로고
    • Inhibitory effects of a new bisphosphonate, minodronate, on proliferation and invasion of a variety of malignant bone tumor cells
    • DOI 10.1002/jor.20177
    • Kubo T., Shimose S., Matsuo T., Tanaka K., Yasunaga Y., Sakai A., Ochi M., Inhibitory effects of a new bisphosphonate, minodronate, on proliferation and invasion of a variety of malignant bone tumor cells Journal of Orthopaedic Research 2006 24 6 1138 1144 (Pubitemid 43870875)
    • (2006) Journal of Orthopaedic Research , vol.24 , Issue.6 , pp. 1138-1144
    • Kubo, T.1    Shimose, S.2    Matsuo, T.3    Tanaka, K.4    Yasunaga, Y.5    Sakai, A.6    Ochi, M.7
  • 85
    • 33746337357 scopus 로고    scopus 로고
    • Zoledronic acid slows down rat primary chondrosarcoma development, recurrent tumor progression after intralesional curretage and increases overall survival
    • DOI 10.1002/ijc.21951
    • Gouin F., Ory B., Rédini F., Heymann D., Zoledronic acid slows down rat primary chondrosarcoma development, recurrent tumor progression after intralesional curretage and increases overall survival International Journal of Cancer 2006 119 5 980 984 (Pubitemid 44116903)
    • (2006) International Journal of Cancer , vol.119 , Issue.5 , pp. 980-984
    • Gouin, F.1    Ory, B.2    Redini, F.3    Heymann, D.4


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