Towards a new understanding and classification of chondrogenic neoplasias of the skeleton - Biochemistry and cell biology of chondrosarcoma and its variants

Virchows Archiv

Volumn 441, Issue 3, 2002, Pages 219-230

  Aigner, T ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Chondrogenesis; Chondroma; Chondrosarcoma; Collagens; Tumor matrix

Indexed keywords

CYTOKERATIN; MOLECULAR MARKER;

ANAPLASTIC CARCINOMA; BIOCHEMISTRY; BONE CANCER; CANCER DIAGNOSIS; CARTILAGE CELL; CELL DIFFERENTIATION; CELL HETEROGENEITY; CHONDROSARCOMA; CYTOLOGY; ENCHONDROMA; EXTRACELLULAR MATRIX; FETUS DEVELOPMENT; GENE EXPRESSION; IMAGE ANALYSIS; IN VITRO STUDY; IN VIVO STUDY; MESENCHYME; OSTEOCHONDROMA; PHENOTYPE; PRIORITY JOURNAL; PROGNOSIS; REVIEW; TUMOR CELL; TUMOR CLASSIFICATION;

ANIMALS; BONE NEOPLASMS; CHONDROCYTES; CHONDROSARCOMA; COLLAGEN TYPE II; HUMANS; IMMUNOHISTOCHEMISTRY; PHENOTYPE; TUMOR MARKERS, BIOLOGICAL;

EID: 0036380586     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-002-0641-x     Document Type: Review

References (74)

1. Aigner T, Unni KK (1999) Is dedifferentiated chondrosarcoma a "de-differentiated" chondrosarcoma? J Pathol 189:445-447
2. Aigner T, Dietz U, Stöß H, von der Mark K (1995) Differential expression of collagen types I, II, III, and X in human osteophytes. Lab Invest 73:236-243
3. Aigner T, Dertinger S, Vornehm SI, Dudhia J, von der Mark K, Kirchner T (1997) Phenotypic diversity of neoplastic chondrocytes and extracellular matrix gene expression in cartilaginous neoplasms. Am J Pathol 150:2133-2141
4. Aigner T, Frischholz S, Dertinger S, Beier F, Girkontaité I, von der Mark K (1997) Type X collagen expression and hypertrophic differentiation in chondrogenic neoplasms. Histochem Cell Biol 107:435-440
5. Aigner T, Dertinger S, Neureiter D, Kirchner T (1998) De-differentiated chondrosarcoma is not a "de-differentiated" chondrosarcoma. Histopathology 33:11-19
6. Aigner T, Neureiter D, Völker U, Belke J, Kirchner T (1998) Epithelial-mesenchymal differentiation and extracellular matrix gene expression in pleomorphic adenomas of the salivary glands. J Pathol 186:178-185
7. Aigner T, Loos S, Müller S, Sandell LJ, Perris R, Unni KK, Kirchner T (2000) Cell differentiation and matrix gene expression in mesenchymal chondrosarcomas. Am J Pathol 156:1327-1335
8. Angervall L, Kindblom LG (1980) Clear-cell chondrosarcoma. Virchows Arch 389:27-41
9. Benya PD, Padilla SR, Nimni ME (1978) Independent regulation of collagen types by chondrocytes during the loss of differentiated function in culture. Cell 15:1313-1321
10. Björnsson J, Unni KK, Dahlin DC, Beabout JW, Sim FH (1984) Clear cell chondrosarcoma of bone. Am J Surg Pathol 8:223-230
11. Björnsson J, Unni KK, McLeod RA, Pritchard DJ, Ilstrup DM (1998) Primary chondrosarcoma of long bones and limb girdle. Cancer 83:2105-2119
12. Bosse A, Ueda Y, Wuisman P, Jones DB, Vollmer E, Roessner A (1991) Histogenesis of clear cell chondrosarcoma. An immunohistochemical study with osteonectin, a non-collagenous structure protein. J Cancer Res Clin Oncol 117:43-49
13. Bovee JV, van den Broek LJ, Cleton-Jansen AM, Hogendoorn P C (2000) Up-regulation of PTHrP and Bcl-2 expression characterizes the progression of osteochondroma towards peripheral chondrosarcoma and is a late event in central chondrosarcoma. Lab Invest 80:1925-1934
14. Bovée JVMG, Cleton-Jansen A-M, Rosenberg C, Tamininau AHM, Cornelisse CJ, Hogendoorn PCW (1999) Molecular genetic characterization of both components of a dedifferentiated chondrosarcoma, with implications for its histogenesis. J Pathol 189:454-462
15. Böhme K, Conscience-Egli M, Tschan T, Winterhalter KH, Bruckner P (1992) Induction of proliferation or hypertrophy of chondrocytes in serum-free culture: the role of insulin-like growth factor-I, insulin, or thyroxine. J Cell Biol 116:1035-1042
16. Cancedda FD, Gentili C, Manduca P, Cancedda R (1992) Hypertrophic chondrocytes undergo further differentiation in culture. J Cell Biol 117:427-435
17. Cancedda R, Descalzi-Cancedda F, Castagnola P (1995) Chondrocyte differentiation. Int Rev Cytol 159:265-358
18. Capanna R, Bertoni F, Bettelli G, Picci P, Bacchini P, Present D, Giunti A, Campanacci M (1988) Dedifferentiated chondrosarcoma. J Bone Joint Surg Am 70:60-69
19. Catresana JS, Barrios C, Gómez L, Kreicbergs A (1992) Amplification of the c-myc proto-oncogene in human chondrosarcoma. Diagn Mol Pathol 1:235-238
20. Dahlin DC (1956) Chondromyxoid fibroma of bone, with emphasis on its morphological relationship to benign chondroblastoma. Cancer 9:195-203
21. Dahlin DC, Beabout JW (1971) Dedifferentiation of low-grade chondrosarcomas. Cancer 28:461-466
22. Dorfman HD, Czerniak B (1998) Bone tumors. Mosby, St. Louis, pp 1-1261
23. Eriksson AI, Schiller A, Mankin HJ (1980) The management of chondrosarcoma of bone. Clin Orthop 153:44-66
24. Evans HL, Ayala AG, Romsdahl MM (1977) Prognostic factors in chondrosarcoma of bone. Cancer 40:818-831
25. Fadda M, Manunta A, Rinonapoli G, Zirattu G, De Santis E (1994) Ultrastructural appearance of chondroblastoma. Int Orthop 18:389-392
26. Fechner RE, Mills SE (1993) Tumors of the bones and joints. Armed Forces Institute of Pathology, Washington DC
27. Girkontaité I, Frischholz S, Lammi P, Wagner K, Swoboda B, Aigner T, von der Mark K (1996) Immunolocalization of type X collagen in normal fetal and adult osteoarthritic cartilage with monoclonal antibodies. Matrix Biol 15:231-238
28. Gitelis S, Bertoni F, Picci P, Campanacci M (1981) Chondrosarcoma of bone. J Bone Joint Surg Am 63:1248-1257
29. Gravanis MB, Giansanti JS (1971) Benign chondroblastoma: report of four cases with a discussion of the presence of ossification. Am J Clin Pathol 55:624-631
30. Grundmann E, Roessner A, Immenkamp M (1981) Tumor cell types in osteosarcoma as revealed by electron microscopy. Virchows Arch 36:257-273
31. Hasegawa T, Seki K, Yang P, Hirose T, Hizawa K, Wada T, Wakabayashi J-I (1995) Differentiation and proliferative activity in benign and malignant cartilage tumors of bone. Hum Pathol 26:838-845
32. Hiltunen A, Aro HT, Vuorio E (1993) Regulation of extracellular matrix genes during fracture healing in mice. Clin Orthop 297:23-27
33. Jundt G, Schulz A, Berghäuser K-H, Fisher LW, Gehron-Robey P, Termine JD (1989) Immunocytochemical identification of osteogenic bone tumors by osteonectin antibodies. Virchows Arch 414:345-353
34. Kirsch T, Swoboda B, von der Mark K (1992) Ascorbate independent differentiation of human chondrocytes in vitro: simultaneous expression of type I and X collagens and matrix mineralization. Differentiation 52:89-100
35. Klareskog L, Johnell O, Hulth A, Holmdahl R, Rubin K (1986) Reactivity of monoclonal anti type II collagen antibodies with cartilage and synovial tissue in rheumatoid arthritis and osteoarhtritis. Arthritis Rheum 29:730-738
36. Kreicbergs A, Boquist L, Borssén B, Larsson S-E (1982) Prognostic factors in chondrosarcoma. Cancer 50:577-583
37. Lefebvre V, Peeters-Joris C, Vaes G (1990) Production of collagens, collagenase and collagenase inhibitor during the dedifferentiation of articular chondrocytes by serial subcultures. Biochim Biophys Acta 1051:266-275
38. Levine GD, Bensch KG (1972) Chondroblastoma - the nature of the basic cell. Cancer 29:1546-1562
39. Lian-Tang W, Tze-Chun L (1993) Clear cell chondrosarcoma of bone. Pathol Res Pract 189:411-415
40. Mankin HJ, Cantley KP, Lippiello L, Schiller AL, Campbell CJ (1980) The biology of human chondrosarcoma. I. Description of the cases, grading, and biochemical analysis. J Bone Joint Surg Am 62:160-175
41. Mankin HJ, Cantley KP, Schiller AL, Lippiello L (1980) The biology of human chondrosarcoma. II. Variation in chemical composition among types and subtypes of benign and malignant cartilage tumors. J Bone Joint Surg Am 62:176-188
42. Mankin HJ, Connor JF, Schiller AL, Perlmutter N, Alho A, McGuire JC (1985) Grading of bone tumors by analysis of nuclear DNA content using flow cytometry. J Bone Joint Surg Am 67:404-413
43. Masi L, Malentacchi C, Campanacci D, Franchi A (2002) Transforming growth factor-β isoform and receptor expression in chondrosarcoma of bone. Virchows Arch 440:491-497
44. Metsäranta M, Young MF, Sandberg M, Termine JD, Vuorio E (1989) Localization of osteonectin expression in human fetal skeletal tissues by in situ hybridization. Calcif Tissue Int 45:146-152
45. Monda L, Wick MR (1985) S-100 protein immunostaining in the differential diagnosis of chondroblastoma. Hum Pathol 16:287-293
46. Nakamura Y, Becker LE, Marks A (1983) S-100 protein in tumors of cartilage and bone. Cancer 52:1820-1824
47. Nielson GP, Keel B, Dickersin GR, Selig MK, Bahn AK, Rosenberg AE (1999) Chondromyxoid fibroma: a tumor showing myofibroblastic, myochondroblastic, and chondrocytic differentiation. Mod Pathol 12:514-517
48. Oganesian A, Zhu Y, Sandell LJ (1997) Type IIA procollagen amino propeptide is localized in human embryonic tissues. J Histochem Cytochem 45:1469-1480
49. Okajima K, Honda I, Kitagawa T (1988) Immunohistochemical distribution of S-100 protein in tumors and tumor-like lesions of bone and cartilage. Cancer 61:792-799
50. Rahimi A, Beabout JW, Ivins JC, Dahlin DC (1972) Chondromyxoid fibroma: a clinicopathologic study of 76 cases. Cancer 30:726-736
51. Reichenberger E, Aigner T, von der Mark K, Stöss H, Bertling W (1991) In situ hybridization studies on the expression of type X collagen in fetal human cartilage. Dev Biol 148:562-572
52. Remberger K, Gay SW (1977) Immunohistochemical demonstration of different collagen types in the normal epiphyseal plate and in benign and malignant tumors of the bone. Zeitung Krebsforschung 90:95-106
53. Roach HI, Erenpreisa J, Aigner T (1995) Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis. J Cell Biol 131:483-494
54. Ronot X, Hecquet C, Jaffray P, Guiguet M, Adolphe M, Fontagne J, Lechat P (1983) Proliferation kinetics of rabbit articular chondrocytes in primary culture and at the first passage. Cell Tissue Kinet 16:531-537
55. Sandell LJ, Morris NP, Robbins JR, Goldring MB (1991) Alternatively spliced type II procollagen mRNAs define distinct populations of cells during vertebral development: differential expression of the aminopropeptide. J Cell Biol 114:1307-1319
56. Sanerkin NG (1980) The diagnosis and grading of chondrosarcoma of bone. Cancer 45:582-594
57. Sanerkin NG, Woods CG (1979) Fibrosarcomata and malignant fibrous histiocytoma arising in relation to enchondromata. J Bone Joint Surg Br 61:366-372
58. Schajowicz F (1994) Tumors and tumorlike lesions of bone. Springer, Berlin Heidelberg New York
59. Schajowicz F, Gallardo H (1971) Chondromyxoid fibroma (fibromyxoid chondroma) of bone. J Bone Joint Surg Br 53:198-216
60. Söder S, Inwards C, Müller S, Kirchner T, Aigner T (2001) Cell biology and matrix biochemistry of chondromyxoid fibroma. Am J Clin Pathol 116:271-277
61. Specks U, Mayer U, Nischt R, Spissinger T, Mann K, Timpl R, Engel J, Chu M-L (1992) Structure of recombinant N-terminal globule of type VI collagen α3 chain and its binding to heparin and hyaluronan. EMBO J 11:4281-4290
62. Steiner GC (1979) Ultrastructure of benign cartilagenous tumors of intraosseous origin. Hum Pathol 10:71-86
63. Steiner GC, Mirra JM, Bullough PG (1973) Mesenchymal chondrosarcoma - a study of the ultrastructure. Cancer 32:926-939
64. Tétu B, Ordónez NG, Ayala AG, Mackay B (1986) Chondrosarcoma with additional mesenchymal component (dedifferentiated chondrosarcoma)-II. An immunohistochemical and electron microscopic study. Cancer 58:287-298
65. Ueda Y, Oda Y, Tsuchiya H, Tomita K, Nakanishi I (1990) Immunohistological study on collagenous proteins of benign and malignant human cartilagenous tumours of bone. Virchows Arch 417:291-297
66. Unni KK (1996) Dahlin's bone tumors. Lippincott-Raven, Philadelphia, pp 1-463
67. Vornehm SI, Dudhia J, von der Mark K, Aigner T (1996) Expression of collagen types IX and XI as well as other major cartilage matrix components by human fetal chondrocytes in vivo. Matrix Biol 15:91-98
68. Weber KL, Bolander ME, Rock MG, Pritchard D, Sarkar G (1998) Evidence for the upregulation of osteogenic protein-1 mRNA expression in musculoskeletal neoplasms. J Orthop Res 16:8-14
69. Weiss A-PC, Dorfman HD (1986) S-100 protein in human cartilage lesions. J Bone Joint Surg Am 68:521-526
70. Welkerling H, Dreyer T, Delling G (1991) Morphological typing of chondrosarcoma: a study of 94 cases. Virchows Arch 418:419-425
71. Wick MR, Siegal GP, Mills SE, Thompson RC, Sawhney D, Fechner RE (1987) Dedifferentiated chondrosarcoma of bone. An immunohistochemical and lectin-histochemical study. Virchows Arch 411:23-32
72. Wrba F, Gullick WJ, Fertl H, Amann G, Salzer-Kuntschik M (1989) Immunohistochemical detection of the c-erbB-2 proto-oncogene product in normal, benign and malignant cartilage tissues. Histopathology 15:71-76
73. Wu CT, Inwards CY, O'Laughlin S, Rock MG, Beabout JW, Unni KK (1997) Chondromyxoid fibroma of bone: a clinicopathologic review of 278 cases. Hum Pathol 29:438-446
74. Yoshikawa H, Rettig WJ, Lane JM, Takaoka K, Alderman E, Rup B, Rosen V, Healey JH, Huvos AG, Garin-Chesa P (1994) Immunohistochemical detection of bone morphogenetic proteins in bone and soft-tissue sarcomas. Cancer 74:842-847