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Volumn 62, Issue , 2011, Pages 251-277

Pharmacology, Signaling and Physiological Relevance of the G Protein-coupled Receptor 55

Author keywords

Cancer; Cannabinoid; CNS; GPR55; Inflammation; LPI

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; 1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N MORPHOLINO 1H PYRAZOLE 3 CARBOXAMIDE; 2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; ANANDAMIDE; BETA GALACTOSIDASE; CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; ENDOCANNABINOID; FORMYLMETHIONYLLEUCYLPHENYLALANINE; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 55; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 8; LYSOPHOSPHATIDIC ACID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 3; MYELOPEROXIDASE; PALMIDROL; PROTEIN ABN CBD; PROTEIN C FOS; REACTIVE OXYGEN METABOLITE; RIMONABANT; SPHINGOSINE 1 PHOSPHATE; UNCLASSIFIED DRUG;

EID: 80052661509     PISSN: 10543589     EISSN: 15578925     Source Type: Book Series    
DOI: 10.1016/B978-0-12-385952-5.00004-X     Document Type: Chapter
Times cited : (29)

References (105)
  • 3
    • 78651393400 scopus 로고    scopus 로고
    • The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK
    • Andradas C., Caffarel M.M., Perez-Gomez E., Salazar M., Lorente M., Velasco G., et al. The orphan G protein-coupled receptor GPR55 promotes cancer cell proliferation via ERK. Oncogene 2011, 30:245-252.
    • (2011) Oncogene , vol.30 , pp. 245-252
    • Andradas, C.1    Caffarel, M.M.2    Perez-Gomez, E.3    Salazar, M.4    Lorente, M.5    Velasco, G.6
  • 6
    • 35148832669 scopus 로고    scopus 로고
    • Regulation of [Ca2+]i oscillations in mouse pancreatic islets by adrenergic agonists
    • Baltrusch S., Lenzen S. Regulation of [Ca2+]i oscillations in mouse pancreatic islets by adrenergic agonists. Biochemical and Biophysical Research Communications 2007, 363:1038-1043.
    • (2007) Biochemical and Biophysical Research Communications , vol.363 , pp. 1038-1043
    • Baltrusch, S.1    Lenzen, S.2
  • 9
    • 0036278032 scopus 로고    scopus 로고
    • Targeting the endocannabinoid system in cancer therapy: A call for further research
    • Bifulco M., Di M.V. Targeting the endocannabinoid system in cancer therapy: A call for further research. Nature Medicine 2002, 8:547-550.
    • (2002) Nature Medicine , vol.8 , pp. 547-550
    • Bifulco, M.1    Di, M.V.2
  • 11
    • 0034948614 scopus 로고    scopus 로고
    • Evidence for a new G protein-coupled cannabinoid receptor in mouse brain
    • Breivogel C.S., Griffin G., Di M.V., Martin B.R. Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. Molecular Pharmacology 2001, 60:155-163.
    • (2001) Molecular Pharmacology , vol.60 , pp. 155-163
    • Breivogel, C.S.1    Griffin, G.2    Di, M.V.3    Martin, B.R.4
  • 14
  • 16
    • 0032537734 scopus 로고    scopus 로고
    • Control of pain initiation by endogenous cannabinoids
    • Calignano A., La Rana G., Giuffrida A., Piomelli D. Control of pain initiation by endogenous cannabinoids. Nature 1998, 394:277-281.
    • (1998) Nature , vol.394 , pp. 277-281
    • Calignano, A.1    La Rana, G.2    Giuffrida, A.3    Piomelli, D.4
  • 17
    • 44749087833 scopus 로고    scopus 로고
    • Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes
    • Cinar R., Freund T.F., Katona I., Mackie K., Szucs M. Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes. Neurochemistry International 2008, 52:1402-1409.
    • (2008) Neurochemistry International , vol.52 , pp. 1402-1409
    • Cinar, R.1    Freund, T.F.2    Katona, I.3    Mackie, K.4    Szucs, M.5
  • 18
    • 0033152165 scopus 로고    scopus 로고
    • Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN
    • Davies M.A., Koul D., Dhesi H., Berman R., McDonnell T.J., McConkey D., et al. Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN. Cancer Research 1999, 59:2551-2556.
    • (1999) Cancer Research , vol.59 , pp. 2551-2556
    • Davies, M.A.1    Koul, D.2    Dhesi, H.3    Berman, R.4    McDonnell, T.J.5    McConkey, D.6
  • 22
    • 0028202831 scopus 로고
    • Elevated levels and mitogenic activity of lysophosphatidylinositol in k-ras-transformed epithelial cells
    • Falasca M., Corda D. Elevated levels and mitogenic activity of lysophosphatidylinositol in k-ras-transformed epithelial cells. European Journal of Biochemistry 1994, 221:383-389.
    • (1994) European Journal of Biochemistry , vol.221 , pp. 383-389
    • Falasca, M.1    Corda, D.2
  • 23
    • 0032493062 scopus 로고    scopus 로고
    • Release of the mitogen lysophosphatidylinositol from H-Ras-transformed fibroblasts; a possible mechanism of autocrine control of cell proliferation
    • Falasca M., Iurisci C., Carvelli A., Sacchetti A., Corda D. Release of the mitogen lysophosphatidylinositol from H-Ras-transformed fibroblasts; a possible mechanism of autocrine control of cell proliferation. Oncogene 1998, 16:2357-2365.
    • (1998) Oncogene , vol.16 , pp. 2357-2365
    • Falasca, M.1    Iurisci, C.2    Carvelli, A.3    Sacchetti, A.4    Corda, D.5
  • 24
    • 77952627758 scopus 로고    scopus 로고
    • A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells
    • Ford L.A., Roelofs A.J., Anavi-Goffer S., Mowat L., Simpson D.G., Irving A.J., et al. A role for L-alpha-lysophosphatidylinositol and GPR55 in the modulation of migration, orientation and polarization of human breast cancer cells. British Journal of Pharmacology 2010, 160:762-771.
    • (2010) British Journal of Pharmacology , vol.160 , pp. 762-771
    • Ford, L.A.1    Roelofs, A.J.2    Anavi-Goffer, S.3    Mowat, L.4    Simpson, D.G.5    Irving, A.J.6
  • 26
    • 0038024615 scopus 로고    scopus 로고
    • The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
    • Fredriksson R., Lagerstrom M.C., Lundin L.G., Schioth H.B. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Molecular Pharmacology 2003, 63:1256-1272.
    • (2003) Molecular Pharmacology , vol.63 , pp. 1256-1272
    • Fredriksson, R.1    Lagerstrom, M.C.2    Lundin, L.G.3    Schioth, H.B.4
  • 27
    • 17344380844 scopus 로고    scopus 로고
    • Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation
    • Galve-Roperh I., Sanchez C., Cortes M.L., Gómez d.P., Izquierdo M., Guzman M. Anti-tumoral action of cannabinoids: Involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation. Nature Medicine 2000, 6:313-319.
    • (2000) Nature Medicine , vol.6 , pp. 313-319
    • Galve-Roperh, I.1    Sanchez, C.2    Cortes, M.L.3    Gómez, D.P.4    Izquierdo, M.5    Guzman, M.6
  • 29
    • 0142166330 scopus 로고    scopus 로고
    • Cannabinoids: Potential anticancer agents
    • Guzman M. Cannabinoids: Potential anticancer agents. Nature Reviews. Cancer 2003, 3:745-755.
    • (2003) Nature Reviews. Cancer , vol.3 , pp. 745-755
    • Guzman, M.1
  • 30
    • 0036753757 scopus 로고    scopus 로고
    • Pharmacological separation of cannabinoid sensitive receptors on hippocampal excitatory and inhibitory fibers
    • Hajos N., Freund T.F. Pharmacological separation of cannabinoid sensitive receptors on hippocampal excitatory and inhibitory fibers. Neuropharmacology 2002, 43:503-510.
    • (2002) Neuropharmacology , vol.43 , pp. 503-510
    • Hajos, N.1    Freund, T.F.2
  • 31
    • 0035801320 scopus 로고    scopus 로고
    • Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus
    • Hajos N., Ledent C., Freund T.F. Novel cannabinoid-sensitive receptor mediates inhibition of glutamatergic synaptic transmission in the hippocampus. Neuroscience 2001, 106:1-4.
    • (2001) Neuroscience , vol.106 , pp. 1-4
    • Hajos, N.1    Ledent, C.2    Freund, T.F.3
  • 32
    • 0032517566 scopus 로고    scopus 로고
    • Adverse effects of cannabis
    • Hall W., Solowij N. Adverse effects of cannabis. The Lancet 1998, 352:1611-1616.
    • (1998) The Lancet , vol.352 , pp. 1611-1616
    • Hall, W.1    Solowij, N.2
  • 33
    • 4043145966 scopus 로고    scopus 로고
    • CB1 cannabinoid receptors mediate anxiolytic effects: Convergent genetic and pharmacological evidence with CB1-specific agents
    • Haller J., Varga B., Ledent C., Freund T.F. CB1 cannabinoid receptors mediate anxiolytic effects: Convergent genetic and pharmacological evidence with CB1-specific agents. Behavioural Pharmacology 2004, 15:299-304.
    • (2004) Behavioural Pharmacology , vol.15 , pp. 299-304
    • Haller, J.1    Varga, B.2    Ledent, C.3    Freund, T.F.4
  • 34
    • 54049144180 scopus 로고    scopus 로고
    • Wiring and firing neuronal networks: Endocannabinoids take center stage
    • Harkany T., Mackie K., Doherty P. Wiring and firing neuronal networks: Endocannabinoids take center stage. Current Opinion in Neurobiology 2008, 18:338-345.
    • (2008) Current Opinion in Neurobiology , vol.18 , pp. 338-345
    • Harkany, T.1    Mackie, K.2    Doherty, P.3
  • 35
    • 58249109364 scopus 로고    scopus 로고
    • The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation
    • Henstridge C.M., Balenga N.A., Ford L.A., Ross R.A., Waldhoer M., Irving A.J. The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation. The FASEB Journal 2009, 23:183-193.
    • (2009) The FASEB Journal , vol.23 , pp. 183-193
    • Henstridge, C.M.1    Balenga, N.A.2    Ford, L.A.3    Ross, R.A.4    Waldhoer, M.5    Irving, A.J.6
  • 37
    • 0344441315 scopus 로고    scopus 로고
    • Cellular accumulation of anandamide: Consensus and controversy
    • Hillard C.J., Jarrahian A. Cellular accumulation of anandamide: Consensus and controversy. British Journal of Pharmacology 2003, 140:802-808.
    • (2003) British Journal of Pharmacology , vol.140 , pp. 802-808
    • Hillard, C.J.1    Jarrahian, A.2
  • 38
    • 0038561226 scopus 로고    scopus 로고
    • Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery
    • Ho W.S., Hiley C.R. Vasodilator actions of abnormal-cannabidiol in rat isolated small mesenteric artery. British Journal of Pharmacology 2003, 138:1320-1332.
    • (2003) British Journal of Pharmacology , vol.138 , pp. 1320-1332
    • Ho, W.S.1    Hiley, C.R.2
  • 39
    • 0031776783 scopus 로고    scopus 로고
    • The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain
    • Jaggar S.I., Hasnie F.S., Sellaturay S., Rice A.S. The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain. Pain 1998, 76:189-199.
    • (1998) Pain , vol.76 , pp. 189-199
    • Jaggar, S.I.1    Hasnie, F.S.2    Sellaturay, S.3    Rice, A.S.4
  • 41
    • 35648959293 scopus 로고    scopus 로고
    • The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects
    • Johns D.G., Behm D.J., Walker D.J., Ao Z., Shapland E.M., Daniels D.A., et al. The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects. British Journal of Pharmacology 2007, 152:825-831.
    • (2007) British Journal of Pharmacology , vol.152 , pp. 825-831
    • Johns, D.G.1    Behm, D.J.2    Walker, D.J.3    Ao, Z.4    Shapland, E.M.5    Daniels, D.A.6
  • 42
    • 57049102251 scopus 로고    scopus 로고
    • End of the line for cannabinoid receptor 1 as an anti-obesity target?
    • Jones D. End of the line for cannabinoid receptor 1 as an anti-obesity target?. Nature Reviews. Drug Discovery 2008, 7:961-962.
    • (2008) Nature Reviews. Drug Discovery , vol.7 , pp. 961-962
    • Jones, D.1
  • 45
    • 51349141952 scopus 로고    scopus 로고
    • Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
    • Katona I., Freund T.F. Endocannabinoid signaling as a synaptic circuit breaker in neurological disease. Nature Medicine 2008, 14:923-930.
    • (2008) Nature Medicine , vol.14 , pp. 923-930
    • Katona, I.1    Freund, T.F.2
  • 46
    • 0029812311 scopus 로고    scopus 로고
    • The classification of seven transmembrane receptors in recombinant expression systems
    • Kenakin T. The classification of seven transmembrane receptors in recombinant expression systems. Pharmacological Reviews 1996, 48:413-463.
    • (1996) Pharmacological Reviews , vol.48 , pp. 413-463
    • Kenakin, T.1
  • 47
    • 33744948790 scopus 로고    scopus 로고
    • Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils
    • Kurihara R., Tohyama Y., Matsusaka S., Naruse H., Kinoshita E., Tsujioka T., et al. Effects of peripheral cannabinoid receptor ligands on motility and polarization in neutrophil-like HL60 cells and human neutrophils. The Journal of Biological Chemistry 2006, 281:12908-12918.
    • (2006) The Journal of Biological Chemistry , vol.281 , pp. 12908-12918
    • Kurihara, R.1    Tohyama, Y.2    Matsusaka, S.3    Naruse, H.4    Kinoshita, E.5    Tsujioka, T.6
  • 49
    • 0033555839 scopus 로고    scopus 로고
    • Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
    • Ledent C., Valverde O., Cossu G., Petitet F., Aubert J.F., Beslot F., et al. Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 1999, 283:401-404.
    • (1999) Science , vol.283 , pp. 401-404
    • Ledent, C.1    Valverde, O.2    Cossu, G.3    Petitet, F.4    Aubert, J.F.5    Beslot, F.6
  • 50
    • 35948968634 scopus 로고    scopus 로고
    • Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs
    • Lutz S., Shankaranarayanan A., Coco C., Ridilla M., Nance M.R., Vettel C., et al. Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs. Science 2007, 318:1923-1927.
    • (2007) Science , vol.318 , pp. 1923-1927
    • Lutz, S.1    Shankaranarayanan, A.2    Coco, C.3    Ridilla, M.4    Nance, M.R.5    Vettel, C.6
  • 51
    • 23044495676 scopus 로고    scopus 로고
    • Cannabinoid receptor homo- and heterodimerization
    • Mackie K. Cannabinoid receptor homo- and heterodimerization. Life Sciences 2005, 77:1667-1673.
    • (2005) Life Sciences , vol.77 , pp. 1667-1673
    • Mackie, K.1
  • 52
    • 33646814424 scopus 로고    scopus 로고
    • Cannabinoid receptors and endocannabinoids: Evidence for new players
    • Mackie K., Stella N. Cannabinoid receptors and endocannabinoids: Evidence for new players. The AAPS Journal 2006, 8:E298-E306.
    • (2006) The AAPS Journal , vol.8
    • Mackie, K.1    Stella, N.2
  • 54
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda L.A., Lolait S.J., Brownstein M.J., Young A.C., Bonner T.I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 1990, 346:561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 55
    • 38549130466 scopus 로고    scopus 로고
    • Inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: Evidence for a site distinct from CB1 and CB2
    • McHugh D., Tanner C., Mechoulam R., Pertwee R.G., Ross R.A. Inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: Evidence for a site distinct from CB1 and CB2. Molecular Pharmacology 2008, 73:441-450.
    • (2008) Molecular Pharmacology , vol.73 , pp. 441-450
    • McHugh, D.1    Tanner, C.2    Mechoulam, R.3    Pertwee, R.G.4    Ross, R.A.5
  • 56
    • 0013779962 scopus 로고
    • Hashish. IV. The isolation and structure of cannabinolic cannabidiolic and cannabigerolic acids
    • Mechoulam R., Gaoni Y. Hashish. IV. The isolation and structure of cannabinolic cannabidiolic and cannabigerolic acids. Tetrahedron 1965, 21:1223-1229.
    • (1965) Tetrahedron , vol.21 , pp. 1223-1229
    • Mechoulam, R.1    Gaoni, Y.2
  • 57
    • 38349086382 scopus 로고    scopus 로고
    • CB2 receptor-mediated migration of immune cells: It can go either way
    • Miller A.M., Stella N. CB2 receptor-mediated migration of immune cells: It can go either way. British Journal of Pharmacology 2008, 153:299-308.
    • (2008) British Journal of Pharmacology , vol.153 , pp. 299-308
    • Miller, A.M.1    Stella, N.2
  • 59
    • 0038751939 scopus 로고    scopus 로고
    • Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: Implication of epidermal growth factor receptor down-regulation and ceramide production
    • Mimeault M., Pommery N., Wattez N., Bailly C., Henichart J.P. Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: Implication of epidermal growth factor receptor down-regulation and ceramide production. The Prostate 2003, 56:1-12.
    • (2003) The Prostate , vol.56 , pp. 1-12
    • Mimeault, M.1    Pommery, N.2    Wattez, N.3    Bailly, C.4    Henichart, J.P.5
  • 60
    • 77950630872 scopus 로고    scopus 로고
    • GPR55: Current knowledge and future perspectives of a purported " Type-3" cannabinoid receptor
    • Moriconi A., Cerbara I., Maccarrone M., Topai A. GPR55: Current knowledge and future perspectives of a purported " Type-3" cannabinoid receptor. Current Medicinal Chemistry 2010, 17:1411-1429.
    • (2010) Current Medicinal Chemistry , vol.17 , pp. 1411-1429
    • Moriconi, A.1    Cerbara, I.2    Maccarrone, M.3    Topai, A.4
  • 61
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S., Thomas K.L., bu-Shaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993, 365:61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    bu-Shaar, M.3
  • 62
    • 77957299242 scopus 로고    scopus 로고
    • Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes
    • Navarrete M., Araque A. Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes. Neuron 2010, 68:113-126.
    • (2010) Neuron , vol.68 , pp. 113-126
    • Navarrete, M.1    Araque, A.2
  • 63
    • 78649689791 scopus 로고    scopus 로고
    • GPR55, a lysophosphatidylinositol receptor with cannabinoid sensitivity?
    • Nevalainen T., Irving A.J. GPR55, a lysophosphatidylinositol receptor with cannabinoid sensitivity?. Current Topics in Medicinal Chemistry 2010, 10:799-813.
    • (2010) Current Topics in Medicinal Chemistry , vol.10 , pp. 799-813
    • Nevalainen, T.1    Irving, A.J.2
  • 64
    • 10844265493 scopus 로고    scopus 로고
    • 2-Arachidonoylglycerol: A novel inhibitor of androgen-independent prostate cancer cell invasion
    • Nithipatikom K., Endsley M.P., Isbell M.A., Falck J.R., Iwamoto Y., Hillard C.J., et al. 2-Arachidonoylglycerol: A novel inhibitor of androgen-independent prostate cancer cell invasion. Cancer Research 2004, 64:8826-8830.
    • (2004) Cancer Research , vol.64 , pp. 8826-8830
    • Nithipatikom, K.1    Endsley, M.P.2    Isbell, M.A.3    Falck, J.R.4    Iwamoto, Y.5    Hillard, C.J.6
  • 65
    • 0242361632 scopus 로고    scopus 로고
    • G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: Regulation of cell shape and reactive oxygen species production
    • Niu J., Profirovic J., Pan H., Vaiskunaite R., Voyno-Yasenetskaya T. G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: Regulation of cell shape and reactive oxygen species production. Circulation Research 2003, 93:848-856.
    • (2003) Circulation Research , vol.93 , pp. 848-856
    • Niu, J.1    Profirovic, J.2    Pan, H.3    Vaiskunaite, R.4    Voyno-Yasenetskaya, T.5
  • 66
    • 22044454462 scopus 로고    scopus 로고
    • The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide
    • O'Sullivan S.E., Kendall D.A., Randall M.D. The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide. British Journal of Pharmacology 2005, 145:514-526.
    • (2005) British Journal of Pharmacology , vol.145 , pp. 514-526
    • O'Sullivan, S.E.1    Kendall, D.A.2    Randall, M.D.3
  • 68
    • 0242584643 scopus 로고    scopus 로고
    • Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor
    • Offertaler L., Mo F.M., Batkai S., Liu J., Begg M., Razdan R.K., et al. Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor. Molecular Pharmacology 2003, 63:699-705.
    • (2003) Molecular Pharmacology , vol.63 , pp. 699-705
    • Offertaler, L.1    Mo, F.M.2    Batkai, S.3    Liu, J.4    Begg, M.5    Razdan, R.K.6
  • 69
    • 7644244850 scopus 로고    scopus 로고
    • 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils
    • Oka S., Ikeda S., Kishimoto S., Gokoh M., Yanagimoto S., Waku K., et al. 2-Arachidonoylglycerol, an endogenous cannabinoid receptor ligand, induces the migration of EoL-1 human eosinophilic leukemia cells and human peripheral blood eosinophils. Journal of Leukocyte Biology 2004, 76:1002-1009.
    • (2004) Journal of Leukocyte Biology , vol.76 , pp. 1002-1009
    • Oka, S.1    Ikeda, S.2    Kishimoto, S.3    Gokoh, M.4    Yanagimoto, S.5    Waku, K.6
  • 70
    • 77952954092 scopus 로고    scopus 로고
    • Lysophosphatidylinositol induces rapid phosphorylation of p38 mitogen-activated protein kinase and activating transcription factor 2 in HEK293 cells expressing GPR55 and IM-9 lymphoblastoid cells
    • Oka S., Kimura S., Toshida T., Ota R., Yamashita A., Sugiura T. Lysophosphatidylinositol induces rapid phosphorylation of p38 mitogen-activated protein kinase and activating transcription factor 2 in HEK293 cells expressing GPR55 and IM-9 lymphoblastoid cells. Journal of Biochemistry 2010, 147:671-678.
    • (2010) Journal of Biochemistry , vol.147 , pp. 671-678
    • Oka, S.1    Kimura, S.2    Toshida, T.3    Ota, R.4    Yamashita, A.5    Sugiura, T.6
  • 73
    • 20944436157 scopus 로고    scopus 로고
    • Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
    • Osei-Hyiaman D., Depetrillo M., Pacher P., Liu J., Radaeva S., Batkai S., et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. The Journal of Clinical Investigation 2005, 115:1298-1305.
    • (2005) The Journal of Clinical Investigation , vol.115 , pp. 1298-1305
    • Osei-Hyiaman, D.1    Depetrillo, M.2    Pacher, P.3    Liu, J.4    Radaeva, S.5    Batkai, S.6
  • 74
    • 0030611978 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid CB1 and CB2 receptors
    • Pertwee R.G. Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacology & Therapeutics 1997, 74:129-180.
    • (1997) Pharmacology & Therapeutics , vol.74 , pp. 129-180
    • Pertwee, R.G.1
  • 75
    • 30444457225 scopus 로고    scopus 로고
    • Cannabinoid pharmacology: The first 66years
    • Pertwee R.G. Cannabinoid pharmacology: The first 66years. British Journal of Pharmacology 2006, 147(Suppl. 1):S163-S171.
    • (2006) British Journal of Pharmacology , vol.147 , Issue.SUPPL. 1
    • Pertwee, R.G.1
  • 76
    • 77950653576 scopus 로고    scopus 로고
    • Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists
    • Pertwee R.G. Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists. Current Medicinal Chemistry 2010, 17:1360-1381.
    • (2010) Current Medicinal Chemistry , vol.17 , pp. 1360-1381
    • Pertwee, R.G.1
  • 77
    • 67349196005 scopus 로고    scopus 로고
    • Differential changes in GPR55 during microglial cell activation
    • Pietr M., Kozela E., Levy R., Rimmerman N., Lin Y.H., Stella N., et al. Differential changes in GPR55 during microglial cell activation. FEBS Letters 2009, 583:2071-2076.
    • (2009) FEBS Letters , vol.583 , pp. 2071-2076
    • Pietr, M.1    Kozela, E.2    Levy, R.3    Rimmerman, N.4    Lin, Y.H.5    Stella, N.6
  • 78
    • 78651383853 scopus 로고    scopus 로고
    • The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation
    • Pineiro R., Maffucci T., Falasca M. The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation. Oncogene 2011, 30:142-152.
    • (2011) Oncogene , vol.30 , pp. 142-152
    • Pineiro, R.1    Maffucci, T.2    Falasca, M.3
  • 79
    • 0345118964 scopus 로고    scopus 로고
    • Cannabinoids modulate neuronal firing in the rat basolateral amygdala: Evidence for CB1- and non-CB1-mediated actions
    • Pistis M., Perra S., Pillolla G., Melis M., Gessa G.L., Muntoni A.L. Cannabinoids modulate neuronal firing in the rat basolateral amygdala: Evidence for CB1- and non-CB1-mediated actions. Neuropharmacology 2004, 46:115-125.
    • (2004) Neuropharmacology , vol.46 , pp. 115-125
    • Pistis, M.1    Perra, S.2    Pillolla, G.3    Melis, M.4    Gessa, G.L.5    Muntoni, A.L.6
  • 80
  • 81
    • 0042318499 scopus 로고    scopus 로고
    • Endocannabinoids contribute to short-term but not long-term mGluR-induced depression in the hippocampus
    • Rouach N., Nicoll R.A. Endocannabinoids contribute to short-term but not long-term mGluR-induced depression in the hippocampus. The European Journal of Neuroscience 2003, 18:1017-1020.
    • (2003) The European Journal of Neuroscience , vol.18 , pp. 1017-1020
    • Rouach, N.1    Nicoll, R.A.2
  • 83
    • 0033524644 scopus 로고    scopus 로고
    • Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain
    • Sawzdargo M., Nguyen T., Lee D.K., Lynch K.R., Cheng R., Heng H.H., et al. Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain. Brain Research. Molecular Brain Research 1999, 64:193-198.
    • (1999) Brain Research. Molecular Brain Research , vol.64 , pp. 193-198
    • Sawzdargo, M.1    Nguyen, T.2    Lee, D.K.3    Lynch, K.R.4    Cheng, R.5    Heng, H.H.6
  • 84
    • 77956657852 scopus 로고    scopus 로고
    • Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements
    • Schroder R., Janssen N., Schmidt J., Kebig A., Merten N., Hennen S., et al. Deconvolution of complex G protein-coupled receptor signaling in live cells using dynamic mass redistribution measurements. Nature Biotechnology 2010, 28:943-949.
    • (2010) Nature Biotechnology , vol.28 , pp. 943-949
    • Schroder, R.1    Janssen, N.2    Schmidt, J.3    Kebig, A.4    Merten, N.5    Hennen, S.6
  • 85
    • 77952950690 scopus 로고    scopus 로고
    • Pharmacological characterization of GPR55, a putative cannabinoid receptor
    • Sharir H., Abood M.E. Pharmacological characterization of GPR55, a putative cannabinoid receptor. Pharmacology & Therapeutics 2010, 126:301-313.
    • (2010) Pharmacology & Therapeutics , vol.126 , pp. 301-313
    • Sharir, H.1    Abood, M.E.2
  • 87
    • 0031883978 scopus 로고    scopus 로고
    • Cytosolic calcium oscillations and insulin release in pancreatic islets of Langerhans
    • Soria B., Martin F. Cytosolic calcium oscillations and insulin release in pancreatic islets of Langerhans. Diabetes & Metabolism 1998, 24:37-40.
    • (1998) Diabetes & Metabolism , vol.24 , pp. 37-40
    • Soria, B.1    Martin, F.2
  • 88
    • 0034581196 scopus 로고    scopus 로고
    • Recombinant aequorin as reporter of changes in intracellular calcium in mammalian cells
    • Stables J., Mattheakis L.C., Chang R., Rees S. Recombinant aequorin as reporter of changes in intracellular calcium in mammalian cells. Methods in Enzymology 2000, 327:456-471.
    • (2000) Methods in Enzymology , vol.327 , pp. 456-471
    • Stables, J.1    Mattheakis, L.C.2    Chang, R.3    Rees, S.4
  • 89
    • 51549099779 scopus 로고    scopus 로고
    • The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain
    • Staton P.C., Hatcher J.P., Walker D.J., Morrison A.D., Shapland E.M., Hughes J.P., et al. The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain. Pain 2008, 139:225-236.
    • (2008) Pain , vol.139 , pp. 225-236
    • Staton, P.C.1    Hatcher, J.P.2    Walker, D.J.3    Morrison, A.D.4    Shapland, E.M.5    Hughes, J.P.6
  • 90
    • 77954406421 scopus 로고    scopus 로고
    • Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas
    • Stella N. Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas. Glia 2010, 58:1017-1030.
    • (2010) Glia , vol.58 , pp. 1017-1030
    • Stella, N.1
  • 92
    • 46949104885 scopus 로고    scopus 로고
    • "Inside-Out" signaling of sphingosine-1-phosphate: therapeutic targets
    • Takabe K., Paugh S.W., Milstien S., Spiegel S. "Inside-Out" signaling of sphingosine-1-phosphate: therapeutic targets. Pharmacological Reviews 2008, 60:181-195.
    • (2008) Pharmacological Reviews , vol.60 , pp. 181-195
    • Takabe, K.1    Paugh, S.W.2    Milstien, S.3    Spiegel, S.4
  • 93
    • 33746648129 scopus 로고    scopus 로고
    • To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front
    • Van K.A., Wong K., Knight Z.A., Govaerts C., Hahn K.M., Shokat K.M., et al. To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front. The Journal of Cell Biology 2006, 174:437-445.
    • (2006) The Journal of Cell Biology , vol.174 , pp. 437-445
    • Van, K.A.1    Wong, K.2    Knight, Z.A.3    Govaerts, C.4    Hahn, K.M.5    Shokat, K.M.6
  • 94
    • 0032924113 scopus 로고    scopus 로고
    • Mesenteric vasodilation mediated by endothelial anandamide receptors
    • Wagner J.A., Varga K., Jarai Z., Kunos G. Mesenteric vasodilation mediated by endothelial anandamide receptors. Hypertension 1999, 33:429-434.
    • (1999) Hypertension , vol.33 , pp. 429-434
    • Wagner, J.A.1    Varga, K.2    Jarai, Z.3    Kunos, G.4
  • 95
    • 46249108439 scopus 로고    scopus 로고
    • Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression
    • Waldeck-Weiermair M., Zoratti C., Osibow K., Balenga N., Goessnitzer E., Waldhoer M., et al. Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression. Journal of Cell Science 2008, 121:1704-1717.
    • (2008) Journal of Cell Science , vol.121 , pp. 1704-1717
    • Waldeck-Weiermair, M.1    Zoratti, C.2    Osibow, K.3    Balenga, N.4    Goessnitzer, E.5    Waldhoer, M.6
  • 97
    • 0034087404 scopus 로고    scopus 로고
    • Marijuana and medicine: Assessing the science base: A summary of the 1999 Institute of Medicine report
    • Watson S.J., Benson J.A., Joy J.E. Marijuana and medicine: Assessing the science base: A summary of the 1999 Institute of Medicine report. Archives of General Psychiatry 2000, 57:547-552.
    • (2000) Archives of General Psychiatry , vol.57 , pp. 547-552
    • Watson, S.J.1    Benson, J.A.2    Joy, J.E.3
  • 98
    • 0031714873 scopus 로고    scopus 로고
    • The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery
    • White R., Hiley C.R. The actions of some cannabinoid receptor ligands in the rat isolated mesenteric artery. British Journal of Pharmacology 1998, 125:533-541.
    • (1998) British Journal of Pharmacology , vol.125 , pp. 533-541
    • White, R.1    Hiley, C.R.2
  • 100
    • 77956420080 scopus 로고    scopus 로고
    • Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections
    • Wu C.S., Zhu J., Wager-Miller J., Wang S., O'Leary D., Monory K., et al. Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. The European Journal of Neuroscience 2010, 32:693-706.
    • (2010) The European Journal of Neuroscience , vol.32 , pp. 693-706
    • Wu, C.S.1    Zhu, J.2    Wager-Miller, J.3    Wang, S.4    O'Leary, D.5    Monory, K.6
  • 101
    • 0034015340 scopus 로고    scopus 로고
    • Evaluation of plasma lysophospholipids for diagnostic significance using electrospray ionization mass spectrometry (ESI-MS) analyses
    • Xiao Y., Chen Y., Kennedy A.W., Belinson J., Xu Y. Evaluation of plasma lysophospholipids for diagnostic significance using electrospray ionization mass spectrometry (ESI-MS) analyses. Annals of the New York Academy of Sciences 2000, 905:242-259.
    • (2000) Annals of the New York Academy of Sciences , vol.905 , pp. 242-259
    • Xiao, Y.1    Chen, Y.2    Kennedy, A.W.3    Belinson, J.4    Xu, Y.5
  • 103
    • 66449121455 scopus 로고    scopus 로고
    • Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay
    • Yin H., Chu A., Li W., Wang B., Shelton F., Otero F., et al. Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay. The Journal of Biological Chemistry 2009, 284:12328-12338.
    • (2009) The Journal of Biological Chemistry , vol.284 , pp. 12328-12338
    • Yin, H.1    Chu, A.2    Li, W.3    Wang, B.4    Shelton, F.5    Otero, F.6


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