Determinants, discriminants, conserved residues - a heuristic approach to detection of functional divergence in protein families

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Bharatham, Kavitha ^a,c   Zhang, Zong Hong ^a   Mihalek, Ivana ^a,b  

^a BIOINFORMATICS INSTITUTE   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; FALSE POSITIVE RESULT; GENETIC CONSERVATION; LIGAND BINDING; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RESIDUE ANALYSIS; BIOLOGICAL MODEL; METABOLISM; MOLECULAR LIBRARY; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; RECEIVER OPERATING CHARACTERISTIC; SEQUENCE HOMOLOGY;

AMINO ACID; LIGAND; PROTEIN;

AMINO ACIDS; CONSERVED SEQUENCE; LIGANDS; MODELS, BIOLOGICAL; MULTIGENE FAMILY; PROTEIN INTERACTION MAPS; PROTEINS; ROC CURVE; SEQUENCE HOMOLOGY, AMINO ACID; SMALL MOLECULE LIBRARIES;

EID: 80052626839     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024382     Document Type: Article

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