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Volumn 179, Issue 2, 2011, Pages 1030-1040

In vivo and in vitro evidence that PPARγ Ligands are antagonists of leptin signaling in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; GLUCOCORTICOID RECEPTOR; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEAR RECEPTOR COREPRESSOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; STAT3 PROTEIN;

EID: 80052442662     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.04.026     Document Type: Article
Times cited : (50)

References (49)
  • 1
    • 3543072186 scopus 로고    scopus 로고
    • Overweight, obesity and cancer: Epidemiological evidence and proposed mechanisms
    • E.E. Calle, and R. Kaaks Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms Nat Rev Cancer 4 2004 579 591 (Pubitemid 39025053)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.8 , pp. 579-591
    • Calle, E.E.1    Kaaks, R.2
  • 2
    • 0037083568 scopus 로고    scopus 로고
    • Weight loss in breast cancer patient management
    • DOI 10.1200/JCO.20.4.1128
    • R.T. Chlebowski, E. Aiello, and A. McTiernan Weight loss in breast cancer patient management J Clin Oncol 20 2002 1128 1143 (Pubitemid 34141858)
    • (2002) Journal of Clinical Oncology , vol.20 , Issue.4 , pp. 1128-1143
    • Chlebowski, R.T.1    Aiello, E.2    McTiernan, A.3
  • 5
    • 34547741589 scopus 로고    scopus 로고
    • Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression
    • DOI 10.1677/ERC-06-0068
    • L. Vona-Davis, and D.P. Rose Adipokines as endocrine, paracrine and autocrine factors in breast cancer risk and progression Endocr Relat Cancer 14 2007 189 206 (Pubitemid 47242622)
    • (2007) Endocrine-Related Cancer , vol.14 , Issue.2 , pp. 189-206
    • Vona-Davis, L.1    Rose, D.P.2
  • 9
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: Nuclear control of metabolism
    • B. Desvergne, and W. Wahli Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocr Rev 20 1999 649 688 (Pubitemid 30650602)
    • (1999) Endocrine Reviews , vol.20 , Issue.5 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 10
    • 39449114610 scopus 로고    scopus 로고
    • Thiazolidinediones: Effects on insulin resistance and the cardiovascular system
    • DOI 10.1038/sj.bjp.0707452, PII 0707452
    • C.E. Quinn, P.K. Hamilton, C.J. Lockhart, and G.E. McVeigh Thiazolidinediones: effects on insulin resistance and the cardiovascular system Br J Pharmacol 153 2008 636 645 (Pubitemid 351271751)
    • (2008) British Journal of Pharmacology , vol.153 , Issue.4 , pp. 636-645
    • Quinn, C.E.1    Hamilton, P.K.2    Lockhart, C.J.3    McVeigh, G.E.4
  • 12
    • 0033547443 scopus 로고    scopus 로고
    • Regulation of gene expression by activation of the peroxisome proliferator-activated receptor γ with rosiglitazone (BRL 49653) in human adipocytes
    • J. Rieusset, J. Auwerx, and H. Vidal Regulation of gene expression by activation of the peroxisome proliferator-activated receptor γ with rosiglitazone (BRL 49653) in human adipocytes Biochem Biophys Res Commun 265 1999 265 271
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 265-271
    • Rieusset, J.1    Auwerx, J.2    Vidal, H.3
  • 14
    • 34247380713 scopus 로고    scopus 로고
    • A peroxisome-proliferator activated receptor-γ ligand could regulate the expression of leptin receptor on human hepatic stellate cells
    • DOI 10.1007/s00418-007-0282-x
    • J.I. Lee, Y.H. Paik, K.S. Lee, J.W. Lee, Y.S. Kim, S. Jeong, K.S. Kwon, D.H. Lee, H.G. Kim, Y.W. Shin, and M.A. Kim A peroxisome-proliferator activated receptor-γ ligand could regulate the expression of leptin receptor on human hepatic stellate cells Histochem Cell Biol 127 2007 495 502 (Pubitemid 46632450)
    • (2007) Histochemistry and Cell Biology , vol.127 , Issue.5 , pp. 495-502
    • Lee, J.I.1    Paik, Y.-H.2    Lee, K.S.3    Lee, J.W.4    Kim, Y.S.5    Jeong, S.6    Kwon, K.S.7    Lee, D.H.8    Kim, H.G.9    Shin, Y.W.10    Kim, M.A.11
  • 15
    • 0032702272 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ: A versatile metabolic regulator
    • S. Rocchi, and J. Auwerx Peroxisome proliferator-activated receptor-γ: a versatile metabolic regulator Ann Med 31 1999 342 351 (Pubitemid 29497696)
    • (1999) Annals of Medicine , vol.31 , Issue.5 , pp. 342-351
    • Rocchi, S.1    Auwerx, J.2
  • 19
    • 0032555196 scopus 로고    scopus 로고
    • Ligands for peroxisome proliferator-activated receptorγ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice
    • E. Elstner, C. Mller, K. Koshizuka, E.A. Williamson, D. Park, H. Asou, P. Shintaku, J.W. Said, D. Heber, and H.P. Koeffler Ligands for peroxisome proliferator-activated receptorγ and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice Proc Natl Acad Sci U S A 95 1998 8806 8811
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 8806-8811
    • Elstner, E.1    Mller, C.2    Koshizuka, K.3    Williamson, E.A.4    Park, D.5    Asou, H.6    Shintaku, P.7    Said, J.W.8    Heber, D.9    Koeffler, H.P.10
  • 20
    • 3042815666 scopus 로고    scopus 로고
    • Antineoplastic effects of peroxisome proliferator-activated receptor γ agonists
    • DOI 10.1016/S1470-2045(04)01509-8, PII S1470204504015098
    • C. Grommes, G.E. Landreth, and M.T. Heneka Antineoplastic effects of peroxisome proliferator-activated receptor γ agonists Lancet Oncol 5 2004 419 429 (Pubitemid 38878045)
    • (2004) Lancet Oncology , vol.5 , Issue.7 , pp. 419-429
    • Grommes, C.1    Landreth, G.E.2    Heneka, M.T.3
  • 21
    • 24344455975 scopus 로고    scopus 로고
    • Estrogen receptor α binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor γ signaling in breast cancer cells
    • DOI 10.1158/1078-0432.CCR-04-2453
    • D. Bonofiglio, S. Gabriele, S. Aquila, S. Catalano, M. Gentile, E. Middea, F. Giordano, and S. Estrogen receptor α binds to peroxisome proliferator-activated receptor (PPAR) response element and negatively interferes with PPAR γ signalling in breast cancer cells Clin Cancer Res 11 2005 6139 6147 (Pubitemid 41262940)
    • (2005) Clinical Cancer Research , vol.11 , Issue.17 , pp. 6139-6147
    • Bonofiglio, D.1    Gabriele, S.2    Aquila, S.3    Catalano, S.4    Gentile, M.5    Middea, E.6    Giordano, F.7    Ando, S.8
  • 22
    • 33751517072 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ activates p53 gene promoter binding to the nuclear factor-κB sequence in human MCF7 breast cancer cells
    • DOI 10.1210/me.2006-0192
    • D. Bonofiglio, S. Aquila, S. Catalano, S. Gabriele, M. Belmonte, E. Middea, H. Qi, C. Morelli, M. Gentile, M. Maggiolini, and S. Peroxisome proliferator-activated receptor γ activates p53 gene promoter binding to the nuclear factor-κB sequence in human MCF7 breast cancer cells Mol Endocrinol 20 2006 3083 3092 (Pubitemid 44833557)
    • (2006) Molecular Endocrinology , vol.20 , Issue.12 , pp. 3083-3092
    • Bonofiglio, D.1    Aquila, S.2    Catalano, S.3    Gabriele, S.4    Belmonte, M.5    Middea, E.6    Qi, H.7    Morelli, C.8    Gentile, M.9    Maggiolini, M.10    Ando, S.11
  • 23
    • 58549093767 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ activates fas ligand gene promoter inducing apoptosis in human breast cancer cells
    • D. Bonofiglio, S. Gabriele, S. Aquila, H. Qi, M. Belmonte, S. Catalano, and S. Peroxisome proliferator-activated receptor γ activates fas ligand gene promoter inducing apoptosis in human breast cancer cells Breast Cancer Res Treat 113 2009 423 434
    • (2009) Breast Cancer Res Treat , vol.113 , pp. 423-434
    • Bonofiglio, D.1    Gabriele, S.2    Aquila, S.3    Qi, H.4    Belmonte, M.5    Catalano, S.S.6
  • 24
    • 0025730640 scopus 로고
    • A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
    • N.C. Andrews, and D.V. Faller A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells Nucleic Acids Res 19 1991 2499
    • (1991) Nucleic Acids Res , vol.19 , pp. 2499
    • Andrews, N.C.1    Faller, D.V.2
  • 26
    • 34548565661 scopus 로고    scopus 로고
    • Insulin-like growth factor-I, regulating aromatase expression through steroidogenic factor 1, supports estrogen-dependent tumor leydig cell proliferation
    • DOI 10.1158/0008-5472.CAN-06-4064
    • R. Sirianni, A. Chimento, R. Malivindi, I. Mazzitelli, S., and V. Pezzi Insulin-like growth factor-I, regulating aromatase expression through steroidogenic factor 1, supports estrogen-dependent tumor Leydig cell proliferation Cancer Res 67 2007 8368 8377 (Pubitemid 47395176)
    • (2007) Cancer Research , vol.67 , Issue.17 , pp. 8368-8377
    • Sirianni, R.1    Chimento, A.2    Malivindi, R.3    Mazzitelli, I.4    Ando, S.5    Pezzi, V.6
  • 27
    • 16544384123 scopus 로고    scopus 로고
    • IGF-I receptor, cell-cell adhesion, tumour development and progression
    • DOI 10.1023/B:HIJO.0000032356.98363.a2
    • L. Mauro, and E. Surmacz IGF-I receptor, cell-cell adhesion, tumor development and progression J Mol Histol 35 2004 247 253 (Pubitemid 40585310)
    • (2004) Journal of Molecular Histology , vol.35 , Issue.3 , pp. 247-253
    • Mauro, L.1    Surmacz, E.2
  • 28
    • 0036000280 scopus 로고    scopus 로고
    • Leptin signalling
    • DOI 10.1016/S0898-6568(02)00006-2, PII S0898656802000062
    • G. Sweeney Leptin signalling Cell Signal 14 2002 655 663 (Pubitemid 34518619)
    • (2002) Cellular Signalling , vol.14 , Issue.8 , pp. 655-663
    • Sweeney, G.1
  • 29
    • 2442670123 scopus 로고    scopus 로고
    • Leptin signaling
    • DOI 10.1016/j.physbeh.2004.02.014, PII S0031938404000459
    • R.S. Ahima, and S.Y. Osei Leptin signaling Physiol Behav 81 2004 223 241 (Pubitemid 38670089)
    • (2004) Physiology and Behavior , vol.81 , Issue.2 , pp. 223-241
    • Ahima, R.S.1    Osei, S.Y.2
  • 30
    • 33748789751 scopus 로고    scopus 로고
    • Nuclear receptor corepressors and PPARγ
    • R.N. Cohen Nuclear receptor corepressors and PPARγ Nucl Recept Signal 4 2006 e003
    • (2006) Nucl Recept Signal , vol.4 , pp. 003
    • Cohen, R.N.1
  • 32
    • 43049123157 scopus 로고    scopus 로고
    • Pharmacology of glucocorticoids: Beyond receptors
    • S. van der Laan, and O.C. Meijer Pharmacology of glucocorticoids: beyond receptors Eur J Pharmacol 585 2008 483 491
    • (2008) Eur J Pharmacol , vol.585 , pp. 483-491
    • Van Der Laan, S.1    Meijer, O.C.2
  • 33
    • 58949097528 scopus 로고    scopus 로고
    • Ligand-selective transactivation and transrepression via the glucocorticoid receptor: Role of cofactor interaction
    • K. Ronacher, K. Hadley, C. Avenant, E. Stubsrud, S.S. Simons Jr, A. Louw, and J.P. Hapgood Ligand-selective transactivation and transrepression via the glucocorticoid receptor: role of cofactor interaction Mol Cell Endocrinol 299 2009 219 231
    • (2009) Mol Cell Endocrinol , vol.299 , pp. 219-231
    • Ronacher, K.1    Hadley, K.2    Avenant, C.3    Stubsrud, E.4    Simons, Jr.S.S.5    Louw, A.6    Hapgood, J.P.7
  • 34
    • 46349107847 scopus 로고    scopus 로고
    • DAX-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X-chromosome, gene 1) selectively inhibits transactivation but not transrepression mediated by the glucocorticoid receptor in a LXXLL-dependent manner
    • DOI 10.1210/me.2007-0273
    • J. Zhou, R.H. Oakley, and J.A. Cidlowski DAX-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X-chromosome, gene 1) selectively inhibits transactivation but not transrepression mediated by the glucocorticoid receptor in a LXXLL-dependent manner Mol Endocrinol 22 2008 1521 1534 (Pubitemid 351920388)
    • (2008) Molecular Endocrinology , vol.22 , Issue.7 , pp. 1521-1534
    • Zhou, J.1    Oakley, R.H.2    Cidlowski, J.A.3
  • 35
    • 0032796327 scopus 로고    scopus 로고
    • Etiology of the metabolic syndrome: Potential role of insulin resistance, leptin resistance, and other players
    • P. Zimmet, E.J. Boyko, G.R. Collier, and M. de Courten Etiology of the metabolic syndrome: potential role of insulin resistance, leptin resistance, and other players Ann N Y Acad Sci 892 1999 25 44
    • (1999) Ann N y Acad Sci , vol.892 , pp. 25-44
    • Zimmet, P.1    Boyko, E.J.2    Collier, G.R.3    De Courten, M.4
  • 36
    • 67649641806 scopus 로고    scopus 로고
    • Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling
    • Y. Tang, S. Zheng, and A. Chen Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling Endocrinology 150 2009 3011 3020
    • (2009) Endocrinology , vol.150 , pp. 3011-3020
    • Tang, Y.1    Zheng, S.2    Chen, A.3
  • 38
    • 0030032754 scopus 로고    scopus 로고
    • Genomic structure and promoter analysis of the human obese gene
    • DOI 10.1074/jbc.271.8.3971
    • D.W. Gong, S. Bi, R.E. Pratley, and B.D. Weintraub Genomic structure and promoter analysis of the human obese gene J Biol Chem 271 1996 3971 3974 (Pubitemid 26070491)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.8 , pp. 3971-3974
    • Gong, D.-W.1    Bi, S.2    Pratley, R.E.3    Weintraub, B.D.4
  • 40
    • 17844371033 scopus 로고    scopus 로고
    • Mechanism of the anti-inflammatory effect of thiazolidinediones: Relationship with the glucocorticoid pathway
    • DOI 10.1124/mol.104.004895
    • A. Ialenti, G. Grassia, P. Di Meglio, P. Maffia, M. Di Rosa, and A. Ianaro Mechanism of the anti-inflammatory effect of thiazolidinediones: relationship with the glucocorticoid pathway Mol Pharmacol 67 2005 1620 1628 (Pubitemid 40594161)
    • (2005) Molecular Pharmacology , vol.67 , Issue.5 , pp. 1620-1628
    • Ialenti, A.1    Grassia, G.2    Di Meglio, P.3    Maffia, P.4    Di Rosa, M.5    Ianaro, A.6
  • 41
    • 13244279654 scopus 로고    scopus 로고
    • 2-agonists
    • DOI 10.1074/jbc.M410616200
    • M. Nie, L. Corbett, A.J. Knox, and L. Pang Differential regulation of chemokine expression by peroxisome proliferator-activated receptor γ agonists: interactions with glucocorticoids and β2-agonists J Biol Chem 280 2005 2550 2561 (Pubitemid 40189357)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.4 , pp. 2550-2561
    • Nie, M.1    Corbett, L.2    Knox, A.J.3    Pang, L.4
  • 42
    • 0035813112 scopus 로고    scopus 로고
    • The multifaceted mechanisms of estradiol and estrogen receptor signaling
    • J.M. Hall, J.F. Couse, and K.S. Korach The multifaceted mechanisms of estradiol and estrogen receptor signaling J Biol Chem 276 2001 36869 36872
    • (2001) J Biol Chem , vol.276 , pp. 36869-36872
    • Hall, J.M.1    Couse, J.F.2    Korach, K.S.3
  • 44
    • 63049122784 scopus 로고    scopus 로고
    • Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways
    • S. Ghisletti, W. Huang, K. Jepsen, C. Benner, G. Hardiman, M.G. Rosenfeld, and C.K. Glass Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways Genes Dev 23 2009 681 693
    • (2009) Genes Dev , vol.23 , pp. 681-693
    • Ghisletti, S.1    Huang, W.2    Jepsen, K.3    Benner, C.4    Hardiman, G.5    Rosenfeld, M.G.6    Glass, C.K.7
  • 46
    • 2542486258 scopus 로고    scopus 로고
    • Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors
    • DOI 10.1210/me.2003-0421
    • Q. Wang, J.A. Blackford Jr, L.N. Song, Y. Huang, S. Cho, and S.S. Simons Jr Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors Mol Endocrinol 18 2004 1376 1395 (Pubitemid 38692177)
    • (2004) Molecular Endocrinology , vol.18 , Issue.6 , pp. 1376-1395
    • Wang, Q.1    Blackford Jr., J.A.2    Song, L.-N.3    Huang, Y.4    Cho, S.5    Simons Jr., S.S.6
  • 47
    • 0036535037 scopus 로고    scopus 로고
    • Nuclear receptor corepressor-dependent repression of peroxisome- proliferator-activated receptor δ-mediated transactivation
    • DOI 10.1042/0264-6021:3630157
    • A.M. Krogsdam, C.A. Nielsen, S. Neve, D. Holst, T. Helledie, B. Thomsen, C. Bendixen, S. Mandrup, and K. Kristiansen Nuclear receptor corepressor-dependent repression of peroxisome-proliferator-activated receptor delta-mediated transactivation Biochem J 363 2002 157 165 (Pubitemid 34280622)
    • (2002) Biochemical Journal , vol.363 , Issue.1 , pp. 157-165
    • Krogsdam, A.-M.1    Nielsen, C.A.F.2    Neve, S.3    Holst, D.4    Helledie, T.5    Thomsen, B.6    Bendixen, C.7    Mandrup, S.8    Kristiansen, K.9
  • 48
    • 42749103389 scopus 로고    scopus 로고
    • Nuclear receptor cofactors in PPARγ-mediated adipogenesis and adipocyte energy metabolism
    • E. Powell, P. Kuhn, and W. Xu Nuclear receptor cofactors in PPARγ-mediated adipogenesis and adipocyte energy metabolism PPAR Res 2007 2007 53843
    • (2007) PPAR Res , vol.2007 , pp. 53843
    • Powell, E.1    Kuhn, P.2    Xu, W.3


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