메뉴 건너뛰기




Volumn 127, Issue 5, 2007, Pages 495-502

A peroxisome-proliferator activated receptor-γ ligand could regulate the expression of leptin receptor on human hepatic stellate cells

Author keywords

Extracellular factor regulated kinase; Hepatic stellate cell; Leptin; Leptin receptor; Peroxisome proliferator activated receptor ; Sterol regulatory element binding protein 1c

Indexed keywords

CIGLITAZONE; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLATELET DERIVED GROWTH FACTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C;

EID: 34247380713     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00418-007-0282-x     Document Type: Article
Times cited : (16)

References (44)
  • 2
    • 0034640508 scopus 로고    scopus 로고
    • Activation of downstream signals by the long form of the leptin receptor
    • Banks AS, Davis SM, Bates SH, Myers MG Jr (2000) Activation of downstream signals by the long form of the leptin receptor. J Biol Chem 275:14563-14572
    • (2000) J Biol Chem , vol.275 , pp. 14563-14572
    • Banks, A.S.1    Davis, S.M.2    Bates, S.H.3    Myers Jr, M.G.4
  • 5
    • 0031436148 scopus 로고    scopus 로고
    • Divergent signaling capacities of the long and short isoforms of the leptin receptor
    • Bjorbaek C, Uotani S, Da Silva B, Flier JS (1997) Divergent signaling capacities of the long and short isoforms of the leptin receptor. J Biol Chem 272:32686-32695
    • (1997) J Biol Chem , vol.272 , pp. 32686-32695
    • Bjorbaek, C.1    Uotani, S.2    Da Silva, B.3    Flier, J.S.4
  • 6
    • 3042760032 scopus 로고    scopus 로고
    • The effect of pioglitazone on peroxisome proliferation-activated receptor-γ target genes related to lipid storage in vivo
    • Bogacka I, Bray GA, Xie H, Smith SR (2004) The effect of pioglitazone on peroxisome proliferation-activated receptor-γ target genes related to lipid storage in vivo. Diabetes Care 27:1660-1667
    • (2004) Diabetes Care , vol.27 , pp. 1660-1667
    • Bogacka, I.1    Bray, G.A.2    Xie, H.3    Smith, S.R.4
  • 8
    • 0029894050 scopus 로고    scopus 로고
    • Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes
    • Caleb B, Lazar K, Lazar MA (1996) Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes. Proc Natl Acad Sci 93:5793-5796
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 5793-5796
    • Caleb, B.1    Lazar, K.2    Lazar, M.A.3
  • 9
    • 1042289785 scopus 로고    scopus 로고
    • Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells
    • Cao Q, Mak KM, Ren C, Lieber CS (2004) Leptin stimulates tissue inhibitor of metalloproteinase-1 in human hepatic stellate cells. J Biol Chem 279:4292-4304
    • (2004) J Biol Chem , vol.279 , pp. 4292-4304
    • Cao, Q.1    Mak, K.M.2    Ren, C.3    Lieber, C.S.4
  • 11
    • 0035132330 scopus 로고    scopus 로고
    • PPAR-γ dependent and independent effects on macrophage-gene expession in lipid metabolism and inflammation
    • Chawla A, Barak Y, Nagy L, Liao D, Tontonoz P, Evans RM (2001) PPAR-γ dependent and independent effects on macrophage-gene expession in lipid metabolism and inflammation. Nat Med 7:48-52
    • (2001) Nat Med , vol.7 , pp. 48-52
    • Chawla, A.1    Barak, Y.2    Nagy, L.3    Liao, D.4    Tontonoz, P.5    Evans, R.M.6
  • 12
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter CM, Avilion AA, LeFeuvre CE, Stewart NG, Greider CW, Harley CB, et al (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO J 11:1921-1929
    • (1992) EMBO J , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6
  • 13
    • 0034723290 scopus 로고    scopus 로고
    • Molecular regulation of hepatic Wbrosis, an integrated cellular response to tissue injury
    • Friedman SL (2000) Molecular regulation of hepatic Wbrosis, an integrated cellular response to tissue injury. J Biol Chem 275:2247-2250
    • (2000) J Biol Chem , vol.275 , pp. 2247-2250
    • Friedman, S.L.1
  • 14
    • 0033962940 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells
    • Galli A, Crab D, Price D, Ceni E, Salzano R, Surrenti C, Casini A (2000) Peroxisome proliferator-activated receptor gamma transcriptional regulation is involved in platelet-derived growth factor-induced proliferation of human hepatic stellate cells. Hepatology 31:101-108
    • (2000) Hepatology , vol.31 , pp. 101-108
    • Galli, A.1    Crab, D.2    Price, D.3    Ceni, E.4    Salzano, R.5    Surrenti, C.6    Casini, A.7
  • 15
    • 0036082703 scopus 로고    scopus 로고
    • Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
    • Galli A, Crabb DW, Ceni E, Salzano R, Mello T, Svegliati-Baroni G, et al (2002) Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro. Gastroenterology 122:1924-1940
    • (2002) Gastroenterology , vol.122 , pp. 1924-1940
    • Galli, A.1    Crabb, D.W.2    Ceni, E.3    Salzano, R.4    Mello, T.5    Svegliati-Baroni, G.6
  • 16
    • 0034808310 scopus 로고    scopus 로고
    • History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells
    • Geerts A (2001) History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells. Semin Liver Dis 21:311-335
    • (2001) Semin Liver Dis , vol.21 , pp. 311-335
    • Geerts, A.1
  • 18
    • 0034647567 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on vascular smooth muscle cell activation by angiotensin II
    • Hattori Y, Akimoto K, Kasai K (2000) The effect of thiazolidinediones on vascular smooth muscle cell activation by angiotensin II. Biochem Biophys Res Commun 273:1144-1149
    • (2000) Biochem Biophys Res Commun , vol.273 , pp. 1144-1149
    • Hattori, Y.1    Akimoto, K.2    Kasai, K.3
  • 19
    • 1642524221 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ induces a phenotypic switch from activated to quiescent hepatic stellate cells
    • Hazra S, Xiong S, Wang J, Rippe RA, Chatterjee KK, Tsukamoto H (2004) Peroxisome proliferator-activated receptor γ induces a phenotypic switch from activated to quiescent hepatic stellate cells. J Biol Chem 279:11392-11401
    • (2004) J Biol Chem , vol.279 , pp. 11392-11401
    • Hazra, S.1    Xiong, S.2    Wang, J.3    Rippe, R.A.4    Chatterjee, K.K.5    Tsukamoto, H.6
  • 20
    • 0033023477 scopus 로고    scopus 로고
    • Increased circulating leptin in alcoholic cirrhosis: Relation to release and disposal
    • Henriksen JH, Holst JJ, Moller S, Brinch K, Bendtsen J (1999) Increased circulating leptin in alcoholic cirrhosis: relation to release and disposal. Hepatology 29:1818-1824
    • (1999) Hepatology , vol.29 , pp. 1818-1824
    • Henriksen, J.H.1    Holst, J.J.2    Moller, S.3    Brinch, K.4    Bendtsen, J.5
  • 21
    • 0031051523 scopus 로고    scopus 로고
    • Functional antagonism between ccaat/enhancer binding protein-γ and peroxisome proliferator-activated receptor-γ on the leptin promotor
    • Hollenberg AN, Susulic VS, Madura JP, Zhang B, Moller DE, Tontonoz P, Sarraf P, et al (1997) Functional antagonism between ccaat/enhancer binding protein-γ and peroxisome proliferator-activated receptor-γ on the leptin promotor. J Biol Chem 272:5283-5290
    • (1997) J Biol Chem , vol.272 , pp. 5283-5290
    • Hollenberg, A.N.1    Susulic, V.S.2    Madura, J.P.3    Zhang, B.4    Moller, D.E.5    Tontonoz, P.6    Sarraf, P.7
  • 23
    • 0034927064 scopus 로고    scopus 로고
    • Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals
    • Ikejima K, Honda H, Yoshikawa M, Hirose M, Kitamura T, Takei Y, et al (2001) Leptin augments inflammatory and profibrogenic responses in the murine liver induced by hepatotoxic chemicals. Heptology 34:288-297
    • (2001) Heptology , vol.34 , pp. 288-297
    • Ikejima, K.1    Honda, H.2    Yoshikawa, M.3    Hirose, M.4    Kitamura, T.5    Takei, Y.6
  • 24
    • 0036234147 scopus 로고    scopus 로고
    • Leptin receptor-medicated signaling regulates hepatic Wbrogenesis and remodeling of extracellular matrix in the rat
    • Ikejima K, Takei Y, Honda H, Hirose M, Yoshikawa M, Zhang YJ, et al (2002) Leptin receptor-medicated signaling regulates hepatic Wbrogenesis and remodeling of extracellular matrix in the rat. Gatroenterology 122:1399-1410
    • (2002) Gatroenterology , vol.122 , pp. 1399-1410
    • Ikejima, K.1    Takei, Y.2    Honda, H.3    Hirose, M.4    Yoshikawa, M.5    Zhang, Y.J.6
  • 29
    • 0141532275 scopus 로고    scopus 로고
    • Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
    • Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Oliver D, Bacon BR (2003) Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology 38:1008-1017
    • (2003) Hepatology , vol.38 , pp. 1008-1017
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3    Oliver, D.4    Bacon, B.R.5
  • 30
    • 0024840085 scopus 로고
    • EVect of platelet derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells
    • Pinzani M, Gesualdo L, Sabbah GM, Abbound HE (1989) EVect of platelet derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat-storing cells. J Clin Invest 84:1786-1793
    • (1989) J Clin Invest , vol.84 , pp. 1786-1793
    • Pinzani, M.1    Gesualdo, L.2    Sabbah, G.M.3    Abbound, H.E.4
  • 31
    • 0030091214 scopus 로고    scopus 로고
    • Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis
    • Pinzani M, Milani S, Herbst H, De Franco R, Grappone C, Gentilini A, Caligiuri A, et al (1996) Expression of platelet-derived growth factor and its receptors in normal human liver and during active hepatic fibrogenesis. Am J Pathol 148:785-800
    • (1996) Am J Pathol , vol.148 , pp. 785-800
    • Pinzani, M.1    Milani, S.2    Herbst, H.3    De Franco, R.4    Grappone, C.5    Gentilini, A.6    Caligiuri, A.7
  • 32
    • 0032489223 scopus 로고    scopus 로고
    • Transdifferentiation of rat hepatic stellate cells results in leptin expression
    • Potter JJ, Womack L, Mezey E, Anania FA (1998) Transdifferentiation of rat hepatic stellate cells results in leptin expression. Biochem Biophys Res Commun 244:906-911
    • (1998) Biochem Biophys Res Commun , vol.244 , pp. 906-911
    • Potter, J.J.1    Womack, L.2    Mezey, E.3    Anania, F.A.4
  • 33
    • 0036204924 scopus 로고    scopus 로고
    • Leptin in hepatic fibrosis: Evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice
    • Saxena NK, Ikeda K, Rockey DC, Friedman SL, Anania FA (2002) Leptin in hepatic fibrosis: evidence for increased collagen production in stellate cells and lean littermates of ob/ob mice. Hepatology 35:762-771
    • (2002) Hepatology , vol.35 , pp. 762-771
    • Saxena, N.K.1    Ikeda, K.2    Rockey, D.C.3    Friedman, S.L.4    Anania, F.A.5
  • 34
    • 0038644530 scopus 로고    scopus 로고
    • Leptin induces increased α2(I) collagen gene expression in cultured rat hepatic stellate cells
    • Saxena NK, Saliba G, Floyd JJ, Anania FA (2003) Leptin induces increased α2(I) collagen gene expression in cultured rat hepatic stellate cells. J Biol Chem 89:311-320
    • (2003) J Biol Chem , vol.89 , pp. 311-320
    • Saxena, N.K.1    Saliba, G.2    Floyd, J.J.3    Anania, F.A.4
  • 35
    • 0036130252 scopus 로고    scopus 로고
    • Immortal activated human hepatic stellate cells generated by ectopic telomerase expression
    • Schnabl B, Choi YH, Olsen JC, Hagedorn CH, Brenner DA (2002) Immortal activated human hepatic stellate cells generated by ectopic telomerase expression. Lab Invest 82:323-333
    • (2002) Lab Invest , vol.82 , pp. 323-333
    • Schnabl, B.1    Choi, Y.H.2    Olsen, J.C.3    Hagedorn, C.H.4    Brenner, D.A.5
  • 36
    • 0035336310 scopus 로고    scopus 로고
    • CD 40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells
    • Schwabe RF, Schnabl B, Kweon YO, Brenner DA (2001) CD 40 activates NF-kappa B and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells. J Immunol 166:6812-6819
    • (2001) J Immunol , vol.166 , pp. 6812-6819
    • Schwabe, R.F.1    Schnabl, B.2    Kweon, Y.O.3    Brenner, D.A.4
  • 37
    • 14244257340 scopus 로고    scopus 로고
    • Adipogenic transcriptional regulation of hepatic stellate cells
    • She H, Xiong S, Hazra S, Tsukamoto H (2005) Adipogenic transcriptional regulation of hepatic stellate cells. J Biol Chem 280:4959-4967
    • (2005) J Biol Chem , vol.280 , pp. 4959-4967
    • She, H.1    Xiong, S.2    Hazra, S.3    Tsukamoto, H.4
  • 38
    • 0030955949 scopus 로고    scopus 로고
    • Leptin induces mitogen-activated protein kinase-dependent proliferation of C3H1T1/2 cells
    • Takahashi Y, Okimura Y, Mizuno I, Iida K, Takahashi T, Kaji H, Abe H, et al (1997) Leptin induces mitogen-activated protein kinase-dependent proliferation of C3H1T1/2 cells. J Biol Chem 272:12897-12900
    • (1997) J Biol Chem , vol.272 , pp. 12897-12900
    • Takahashi, Y.1    Okimura, Y.2    Mizuno, I.3    Iida, K.4    Takahashi, T.5    Kaji, H.6    Abe, H.7
  • 39
    • 0030942844 scopus 로고    scopus 로고
    • The leptin receptor
    • Tartaglia LA (1997) The leptin receptor. J Biol Chem 272:6093-6096
    • (1997) J Biol Chem , vol.272 , pp. 6093-6096
    • Tartaglia, L.A.1
  • 40
    • 0028641559 scopus 로고
    • Stimulation of adipogenesis in fibroblasts by PPAR-γ2, a lipid-activated transcription factor
    • Tontonoz P, Hu E, Spiegelman BM (1994) Stimulation of adipogenesis in fibroblasts by PPAR-γ2, a lipid-activated transcription factor. Cell 79:1147-1156
    • (1994) Cell , vol.79 , pp. 1147-1156
    • Tontonoz, P.1    Hu, E.2    Spiegelman, B.M.3
  • 43
    • 0034695479 scopus 로고    scopus 로고
    • A synthetic antagonist for the peroxisome proliferator-activated receptor γ inhibits adipocyte differentiation
    • Wright HM, Clish CB, Mikami T, Hauser S, Yanagi K, Ryuji H, et al (2000) A synthetic antagonist for the peroxisome proliferator-activated receptor γ inhibits adipocyte differentiation. J Biol Chem 275:1873-1877
    • (2000) J Biol Chem , vol.275 , pp. 1873-1877
    • Wright, H.M.1    Clish, C.B.2    Mikami, T.3    Hauser, S.4    Yanagi, K.5    Ryuji, H.6
  • 44
    • 15844415080 scopus 로고    scopus 로고
    • Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in zuncker diabetic fatty rats and db/db mice
    • Zhang B, Graziano MP, Doebber TW, Leibowitz MD, White-Carrington S, Szalkowski DM, Hey PJ, et al (1996) Down-regulation of the expression of the obese gene by an antidiabetic thiazolidinedione in zuncker diabetic fatty rats and db/db mice. J Biol Chem 271:9455-9459
    • (1996) J Biol Chem , vol.271 , pp. 9455-9459
    • Zhang, B.1    Graziano, M.P.2    Doebber, T.W.3    Leibowitz, M.D.4    White-Carrington, S.5    Szalkowski, D.M.6    Hey, P.J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.