Ribosomal protein RPL41 induces rapid degradation of ATF4, a transcription factor critical for tumour cell survival in stress

Journal of Pathology

Volumn 225, Issue 2, 2011, Pages 285-292

  Wang, Aiyuan ^a,b   Xu, Shengqiang ^a   Zhang, Xiaoxian ^a   He, Jie ^a   Yan, Donghui ^a   Yang, Zhangmin ^a   Xiao, Sheng ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b CHINA MEDICAL UNIVERSITY   (China)

Author keywords

angiogenesis; ATF4; hypoxia; RPL41

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CISPLATIN; DNA; PROTEASOME; RIBOSOMAL PROTEIN L41; RIBOSOME PROTEIN; SERINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE ARREST; CELL DEATH; CELL NUCLEUS; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; DOWN REGULATION; DRUG SENSITIZATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; TUMOR CELL;

ACTIVATING TRANSCRIPTION FACTOR 4; CELL LINE, TUMOR; CELL SURVIVAL; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; NEOPLASMS; PHOSPHORYLATION; PROTEIN TRANSPORT; RIBOSOMAL PROTEINS; RNA, SMALL INTERFERING; STRESS, PHYSIOLOGICAL; TRANSFECTION;

EID: 80052439196     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2918     Document Type: Article

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