Probing in vivo trafficking of polymer/DNA micellar nanoparticles using SPECT/CT imaging

Molecular Therapy

Volumn 19, Issue 9, 2011, Pages 1626-1635

  Patil, Rajesh R ^a   Yu, Jianhua ^b   Banerjee, Sangeeta R ^b   Ren, Yong ^a   Leong, Derek ^a   Jiang, Xuan ^a   Pomper, Martin ^b   Tsui, Benjamin ^b   Kraitchman, Dara L ^b   Mao, Hai Quan ^a,c  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA MICELLAR NANOPARTICLE; INDIUM 111; NANOPARTICLE; POLYETHYLENE GLYCOL POLYPHOSPHORAMIDATE; POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; COMPARTMENT MODEL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG ADMINISTRATION ROUTE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG INFUSION; DRUG LIVER LEVEL; DRUG RETENTION; DRUG STABILITY; DRUG TISSUE LEVEL; DRUG UPTAKE; FEMALE; HEART; HYDRODYNAMICS BASED TRANSFECTION; IMAGE ANALYSIS; INTRABILIARY INFUSION; ISOTOPE LABELING; KIDNEY PARENCHYMA; LIVER; LUNG PARENCHYMA; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MICELLE; NONHUMAN; PARTICLE SIZE; QUANTITATIVE ANALYSIS; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPLEEN; STEADY STATE; STOMACH; TISSUE DISTRIBUTION; TRANSPORT KINETICS; WHOLE BODY CT; WHOLE BODY TOMOGRAPHY;

EID: 80052395339     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.128     Document Type: Article

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