String-like micellar nanoparticles formed by complexation of PEG-b-PPA and plasmid DNA and their transfection efficiency

Pharmaceutical Research

Volumn 28, Issue 6, 2011, Pages 1317-1327

  Jiang, Xuan ^a   Leong, Derek ^a   Ren, Yong ^a   Li, Zhiping ^b   Torbenson, Michael S ^b   Mao, Hai Quan ^a  

^a Johns Hopkins University   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

block copolymer; DNA micellar nanoparticles; liver targeted gene delivery; morphology; string like

Indexed keywords

MACROGOL; NANOPARTICLE; PLASMID DNA; POLYPHOSPHORAMIDATE; SODIUM CHLORIDE; STRING LIKE NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; BILE; CONTROLLED STUDY; DRUG STABILITY; DYNAMICS; FEMALE; GENETIC TRANSFECTION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; LIVER; LIVER TOXICITY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SERUM; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

AMIDES; ANIMALS; FEMALE; HEK293 CELLS; HUMANS; LIVER; MALE; MICE; MICE, INBRED BALB C; MICELLES; NANOPARTICLES; PARTICLE SIZE; PHOSPHORIC ACIDS; PLASMIDS; POLYETHYLENE GLYCOLS; RATS; RATS, WISTAR; TRANSFECTION;

EID: 79959890525     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0436-3     Document Type: Article

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