Non-coding nucleotides and amino acids near the active site regulate peptide deformylase expression and inhibitor susceptibility in Chlamydia trachomatis

Microbiology

Volumn 157, Issue 9, 2011, Pages 2569-2581

  Bao, Xiaofeng ^a   Pachikara, Niseema D ^a   Oey, Christopher B ^a   Balakrishnan, Amit ^a   Westblade, Lars F ^b,f   Tan, Ming ^c   Chase Jr , Theodore ^d   Nickels, Bryce E ^e   Fan, Huizhou ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d The State University of New Jersey   (United States)

^e RUTGERS UNIVERSITY   (United States)

^f WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; COMPLEMENTARY DNA; GENOMIC DNA; NUCLEOTIDE; PEPTIDE DEFORMYLASE; RECOMBINANT PROTEIN; RNA; RNA POLYMERASE;

ARTICLE; BACTERIUM CULTURE; CHLAMYDIA TRACHOMATIS; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME INHIBITION; ENZYME KINETICS; GENE EXPRESSION REGULATION; GENE MUTATION; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

5' FLANKING REGION; AMIDOHYDROLASES; AMINO ACID SUBSTITUTION; BASE SEQUENCE; CATALYTIC DOMAIN; CHLAMYDIA TRACHOMATIS; DIPEPTIDES; DRUG RESISTANCE, BACTERIAL; ENZYME INHIBITORS; ENZYME STABILITY; GENE EXPRESSION REGULATION, BACTERIAL; HELA CELLS; HUMANS; KINETICS; MUTATION; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS); CHLAMYDIA TRACHOMATIS;

EID: 80052377663     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.049668-0     Document Type: Article

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