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Volumn 164, Issue 3, 2009, Pages 338-346

Inhibition of chlamydial infection in the genital tract of female mice by topical application of a peptide deformylase inhibitor

Author keywords

Chlamydia; GM6001; Peptide deformylase; Sexually transmitted infection; Topical microbicide

Indexed keywords

AMINES; CELL CULTURE; PROBABILITY DISTRIBUTIONS;

EID: 65549129692     PISSN: 09445013     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micres.2007.05.002     Document Type: Article
Times cited : (7)

References (43)
  • 1
    • 0036843332 scopus 로고    scopus 로고
    • Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis
    • Achilles S.L., Shete P.B., Whaley K.J., Moench T.R., and Cone R.A. Microbicide efficacy and toxicity tests in a mouse model for vaginal transmission of Chlamydia trachomatis. Sex Transm Dis 29 (2002) 655-664
    • (2002) Sex Transm Dis , vol.29 , pp. 655-664
    • Achilles, S.L.1    Shete, P.B.2    Whaley, K.J.3    Moench, T.R.4    Cone, R.A.5
  • 2
    • 22544474147 scopus 로고    scopus 로고
    • Colonization of the rectum by Lactobacillus species and decreased risk of bacterial vaginosis
    • Antonio M.A., Rabe L.K., and Hillier S.L. Colonization of the rectum by Lactobacillus species and decreased risk of bacterial vaginosis. J Infect Dis 192 (2005) 394-398
    • (2005) J Infect Dis , vol.192 , pp. 394-398
    • Antonio, M.A.1    Rabe, L.K.2    Hillier, S.L.3
  • 3
    • 33745188914 scopus 로고    scopus 로고
    • Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen chlamydia trachomatis by targeting peptide deformylase of the bacterium
    • Balakrishnan A., Patel B., Sieber S.A., Chen D., Pachikara N., Zhong G., et al. Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen chlamydia trachomatis by targeting peptide deformylase of the bacterium. J Biol Chem 281 (2006) 16691-16699
    • (2006) J Biol Chem , vol.281 , pp. 16691-16699
    • Balakrishnan, A.1    Patel, B.2    Sieber, S.A.3    Chen, D.4    Pachikara, N.5    Zhong, G.6
  • 4
    • 0036135329 scopus 로고    scopus 로고
    • In vitro microbicidal activities of cecropin peptides D2A21 and D4E1 and gel formulations containing 0.1 to 2% D2A21 against Chlamydia trachomatis
    • Ballweber L.M., Jaynes J.E., Stamm W.E., and Lampe M.F. In vitro microbicidal activities of cecropin peptides D2A21 and D4E1 and gel formulations containing 0.1 to 2% D2A21 against Chlamydia trachomatis. Antimicrob Agents Chemother 46 (2002) 34-41
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 34-41
    • Ballweber, L.M.1    Jaynes, J.E.2    Stamm, W.E.3    Lampe, M.F.4
  • 5
    • 0019462336 scopus 로고
    • A new animal model for the study of Chlamydia trachomatis genital infections: infection of mice with the agent of mouse pneumonitis
    • Barron A.L., White H.J., Rank R.G., Soloff B.L., and Moses E.B. A new animal model for the study of Chlamydia trachomatis genital infections: infection of mice with the agent of mouse pneumonitis. J Infect Dis 143 (1981) 63-66
    • (1981) J Infect Dis , vol.143 , pp. 63-66
    • Barron, A.L.1    White, H.J.2    Rank, R.G.3    Soloff, B.L.4    Moses, E.B.5
  • 6
    • 0242405443 scopus 로고    scopus 로고
    • Adherence of Lactobacillus plantarum P 17630 in soft-gel capsule formulation versus Doderlein's bacillus in tablet formulation to vaginal epithelial cells
    • Bonetti A., Morelli L., Campominosi E., Ganora E., and Sforza F. Adherence of Lactobacillus plantarum P 17630 in soft-gel capsule formulation versus Doderlein's bacillus in tablet formulation to vaginal epithelial cells. Minerva Ginecol 55 (2003) 279-287
    • (2003) Minerva Ginecol , vol.55 , pp. 279-287
    • Bonetti, A.1    Morelli, L.2    Campominosi, E.3    Ganora, E.4    Sforza, F.5
  • 7
    • 0141516252 scopus 로고    scopus 로고
    • Poly(sodium 4-styrene sulfonate): evaluation of a topical microbicide gel against herpes simplex virus type 2 and Chlamydia trachomatis infections in mice
    • Bourne N., Zaneveld L.J., Ward J.A., Ireland J.P., and Stanberry L.R. Poly(sodium 4-styrene sulfonate): evaluation of a topical microbicide gel against herpes simplex virus type 2 and Chlamydia trachomatis infections in mice. Clin Microbiol Infect 9 (2003) 816-822
    • (2003) Clin Microbiol Infect , vol.9 , pp. 816-822
    • Bourne, N.1    Zaneveld, L.J.2    Ward, J.A.3    Ireland, J.P.4    Stanberry, L.R.5
  • 8
    • 24344497940 scopus 로고    scopus 로고
    • Therapeutic potential of peptide deformylase inhibitors
    • Chen D., and Yuan Z. Therapeutic potential of peptide deformylase inhibitors. Expert Opin Invest Drugs 14 (2005) 1107-1116
    • (2005) Expert Opin Invest Drugs , vol.14 , pp. 1107-1116
    • Chen, D.1    Yuan, Z.2
  • 9
    • 0034673093 scopus 로고    scopus 로고
    • Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor
    • Chen D.Z., Patel D.V., Hackbarth C.J., Wang W., Dreyer G., Young D.C., et al. Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor. Biochemistry 39 (2000) 1256-1262
    • (2000) Biochemistry , vol.39 , pp. 1256-1262
    • Chen, D.Z.1    Patel, D.V.2    Hackbarth, C.J.3    Wang, W.4    Dreyer, G.5    Young, D.C.6
  • 10
    • 0028299790 scopus 로고
    • Intravaginal inoculation of mice with the Chlamydia trachomatis mouse pneumonitis biovar results in infertility
    • de la Maza L., Pal S., Khamesipour A., and Peterson E. Intravaginal inoculation of mice with the Chlamydia trachomatis mouse pneumonitis biovar results in infertility. Infect Immunol 62 (1994) 2094-2097
    • (1994) Infect Immunol , vol.62 , pp. 2094-2097
    • de la Maza, L.1    Pal, S.2    Khamesipour, A.3    Peterson, E.4
  • 11
    • 23044442679 scopus 로고    scopus 로고
    • Role of the AcrAB-TolC efflux pump in determining susceptibility of Haemophilus influenzae to the novel peptide deformylase inhibitor LBM415
    • Dean C.R., Narayan S., Daigle D.M., Dzink-Fox J.L., Puyang X., Bracken K.R., et al. Role of the AcrAB-TolC efflux pump in determining susceptibility of Haemophilus influenzae to the novel peptide deformylase inhibitor LBM415. Antimicrob Agents Chemother 49 (2005) 3129-3135
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3129-3135
    • Dean, C.R.1    Narayan, S.2    Daigle, D.M.3    Dzink-Fox, J.L.4    Puyang, X.5    Bracken, K.R.6
  • 12
    • 0036877386 scopus 로고    scopus 로고
    • The association of campus resources for gay, lesbian, and bisexual students with college students' condom use
    • Eisenberg M.E. The association of campus resources for gay, lesbian, and bisexual students with college students' condom use. J Am Coll Health 51 (2002) 109-116
    • (2002) J Am Coll Health , vol.51 , pp. 109-116
    • Eisenberg, M.E.1
  • 14
    • 0026458279 scopus 로고
    • Acquisition and synthesis of folates by obligate intracellular bacteria of the genus Chlamydia
    • Fan H., Brunham R.C., and McClarty G. Acquisition and synthesis of folates by obligate intracellular bacteria of the genus Chlamydia. J Clin Invest 90 (1992) 1803-1811
    • (1992) J Clin Invest , vol.90 , pp. 1803-1811
    • Fan, H.1    Brunham, R.C.2    McClarty, G.3
  • 15
    • 0029924173 scopus 로고    scopus 로고
    • Shedding of the lymphocyte L-selectin adhesion molecule is inhibited by a hydroxamic acid-based protease inhibitor. Identification with an L-selectin-alkaline phosphatase reporter
    • Feehan C., Darlak K., Kahn J., Walcheck B., Spatola A.F., and Kishimoto T.K. Shedding of the lymphocyte L-selectin adhesion molecule is inhibited by a hydroxamic acid-based protease inhibitor. Identification with an L-selectin-alkaline phosphatase reporter. J Biol Chem 271 (1996) 7019-7024
    • (1996) J Biol Chem , vol.271 , pp. 7019-7024
    • Feehan, C.1    Darlak, K.2    Kahn, J.3    Walcheck, B.4    Spatola, A.F.5    Kishimoto, T.K.6
  • 16
    • 1642493617 scopus 로고    scopus 로고
    • Modeling the economic net benefit of a potential vaccination program against ocular infection with Chlamydia trachomatis
    • Frick K.D., Colchero M.A., and Dean D. Modeling the economic net benefit of a potential vaccination program against ocular infection with Chlamydia trachomatis. Vaccine 22 (2004) 689-696
    • (2004) Vaccine , vol.22 , pp. 689-696
    • Frick, K.D.1    Colchero, M.A.2    Dean, D.3
  • 17
    • 0346251026 scopus 로고    scopus 로고
    • Chlamydia-infected cells continue to undergo mitosis and resist induction of apoptosis
    • Greene W., Xiao Y., Huang Y., McClarty G., and Zhong G. Chlamydia-infected cells continue to undergo mitosis and resist induction of apoptosis. Infect Immunol 72 (2004) 451-460
    • (2004) Infect Immunol , vol.72 , pp. 451-460
    • Greene, W.1    Xiao, Y.2    Huang, Y.3    McClarty, G.4    Zhong, G.5
  • 20
    • 33749250965 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinases protects mice from ascending infection and chronic disease manifestations resulting from urogenital Chlamydia muridarum infection
    • Imtiaz M.T., Schripsema J.H., Sigar I.M., Kasimos J.N., and Ramsey K.H. Inhibition of matrix metalloproteinases protects mice from ascending infection and chronic disease manifestations resulting from urogenital Chlamydia muridarum infection. Infect Immunol 74 (2006) 5513-5521
    • (2006) Infect Immunol , vol.74 , pp. 5513-5521
    • Imtiaz, M.T.1    Schripsema, J.H.2    Sigar, I.M.3    Kasimos, J.N.4    Ramsey, K.H.5
  • 21
    • 0032707631 scopus 로고    scopus 로고
    • Experimental gonococcal genital tract infection and opacity protein expression in estradiol-treated mice
    • Jerse A.E. Experimental gonococcal genital tract infection and opacity protein expression in estradiol-treated mice. Infect Immunol 67 (1999) 5699-5708
    • (1999) Infect Immunol , vol.67 , pp. 5699-5708
    • Jerse, A.E.1
  • 22
    • 2442707806 scopus 로고    scopus 로고
    • Potential utility of a peptide deformylase inhibitor (NVP PDF-713) against oxazolidinone-resistant or streptogramin-resistant Gram-positive organism isolates
    • Jones R.N., Moet G.J., Sader H.S., and Fritsche T.R. Potential utility of a peptide deformylase inhibitor (NVP PDF-713) against oxazolidinone-resistant or streptogramin-resistant Gram-positive organism isolates. J Antimicrob Chemother 53 (2004) 804-807
    • (2004) J Antimicrob Chemother , vol.53 , pp. 804-807
    • Jones, R.N.1    Moet, G.J.2    Sader, H.S.3    Fritsche, T.R.4
  • 23
    • 23744466893 scopus 로고    scopus 로고
    • Susceptibility to some antifungal drugs of vaginal lactobacilli isolated from healthy women
    • Kilic E., Aslim B., and Taner Z. Susceptibility to some antifungal drugs of vaginal lactobacilli isolated from healthy women. Drug Metabol Drug Interact 21 (2005) 67-74
    • (2005) Drug Metabol Drug Interact , vol.21 , pp. 67-74
    • Kilic, E.1    Aslim, B.2    Taner, Z.3
  • 25
    • 0037785128 scopus 로고    scopus 로고
    • Structure analysis of peptide deformylases from Streptococcus pneumoniae, Staphylococcus aureus, Thermotoga maritima and Pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
    • Kreusch A., Spraggon G., Lee C.C., Klock H., McMullan D., Ng K., et al. Structure analysis of peptide deformylases from Streptococcus pneumoniae, Staphylococcus aureus, Thermotoga maritima and Pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase. J Mol Biol 330 (2003) 309-321
    • (2003) J Mol Biol , vol.330 , pp. 309-321
    • Kreusch, A.1    Spraggon, G.2    Lee, C.C.3    Klock, H.4    McMullan, D.5    Ng, K.6
  • 26
    • 0031836427 scopus 로고    scopus 로고
    • Susceptibility of Chlamydia trachomatis to chlorhexidine gluconate gel
    • Lampe M.F., Ballweber L.M., and Stamm W.E. Susceptibility of Chlamydia trachomatis to chlorhexidine gluconate gel. Antimicrob Agents Chemother 42 (1998) 1726-1730
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1726-1730
    • Lampe, M.F.1    Ballweber, L.M.2    Stamm, W.E.3
  • 27
    • 15444343493 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors: a structure-activity study
    • Levy D.E., Lapierre F., Liang W., Ye W., Lange C.W., Li X., et al. Matrix metalloproteinase inhibitors: a structure-activity study. J Med Chem 41 (1998) 199-223
    • (1998) J Med Chem , vol.41 , pp. 199-223
    • Levy, D.E.1    Lapierre, F.2    Liang, W.3    Ye, W.4    Lange, C.W.5    Li, X.6
  • 28
    • 3042589336 scopus 로고    scopus 로고
    • Loss of ectodomain shedding due to mutations in the metalloprotease and cysteine-rich/disintegrin domains of the tumor necrosis factor-{alpha} converting enzyme (TACE)
    • Li X., and Fan H. Loss of ectodomain shedding due to mutations in the metalloprotease and cysteine-rich/disintegrin domains of the tumor necrosis factor-{alpha} converting enzyme (TACE). J Biol Chem 279 (2004) 27365-27375
    • (2004) J Biol Chem , vol.279 , pp. 27365-27375
    • Li, X.1    Fan, H.2
  • 30
    • 29244451071 scopus 로고    scopus 로고
    • Antimicrobial activity of N-phthaloylamino acid hydroxamates
    • Matijevic-Sosa J., and Cvetnic Z. Antimicrobial activity of N-phthaloylamino acid hydroxamates. Acta Pharm 55 (2005) 387-399
    • (2005) Acta Pharm , vol.55 , pp. 387-399
    • Matijevic-Sosa, J.1    Cvetnic, Z.2
  • 31
    • 25444508208 scopus 로고    scopus 로고
    • Expression of matrix metalloproteinases subsequent to urogenital Chlamydia muridarum infection of mice
    • Ramsey K.H., Sigar I.M., Schripsema J.H., Shaba N., and Cohoon K.P. Expression of matrix metalloproteinases subsequent to urogenital Chlamydia muridarum infection of mice. Infect Immunol 73 (2005) 6962-6973
    • (2005) Infect Immunol , vol.73 , pp. 6962-6973
    • Ramsey, K.H.1    Sigar, I.M.2    Schripsema, J.H.3    Shaba, N.4    Cohoon, K.P.5
  • 32
    • 33745686049 scopus 로고    scopus 로고
    • Lactobacilli in the female genital tract in relation to other genital microbes and vaginal pH
    • Ronnqvist P.D., Forsgren-Brusk U.B., and Grahn-Hakansson E.E. Lactobacilli in the female genital tract in relation to other genital microbes and vaginal pH. Acta Obstet Gynecol Scand 85 (2006) 726-735
    • (2006) Acta Obstet Gynecol Scand , vol.85 , pp. 726-735
    • Ronnqvist, P.D.1    Forsgren-Brusk, U.B.2    Grahn-Hakansson, E.E.3
  • 33
    • 84930044971 scopus 로고    scopus 로고
    • SAS Institute Inc, Version 8. Cary, NC: SAS Institute, Inc
    • SAS Institute Inc. SAS® user's guide, Version 8. Cary, NC: SAS Institute, Inc.; 1999.
    • (1999) SAS® user's guide
  • 34
    • 0001252269 scopus 로고    scopus 로고
    • Infection and disease epidemiology
    • Stephens R.S. (Ed), ASM Press, Washington, DC
    • Schachter J. Infection and disease epidemiology. In: Stephens R.S. (Ed). Chlamydia intracellular biology, pathogenesis (1999), ASM Press, Washington, DC 139-169
    • (1999) Chlamydia intracellular biology, pathogenesis , pp. 139-169
    • Schachter, J.1
  • 36
    • 11144322917 scopus 로고    scopus 로고
    • Female genital-tract HIV load correlates inversely with Lactobacillus species but positively with bacterial vaginosis and Mycoplasma hominis
    • Sha B.E., Zariffard M.R., Wang Q.J., Chen H.Y., Bremer J., Cohen M.H., et al. Female genital-tract HIV load correlates inversely with Lactobacillus species but positively with bacterial vaginosis and Mycoplasma hominis. J Infect Dis 191 (2005) 25-32
    • (2005) J Infect Dis , vol.191 , pp. 25-32
    • Sha, B.E.1    Zariffard, M.R.2    Wang, Q.J.3    Chen, H.Y.4    Bremer, J.5    Cohen, M.H.6
  • 38
    • 0023675952 scopus 로고
    • The association between genital ulcer disease and acquisition of HIV infection in homosexual men
    • Stamm W.E., Handsfield H.H., Rompalo A.M., Ashley R.L., Roberts P.L., and Corey L. The association between genital ulcer disease and acquisition of HIV infection in homosexual men. JAMA 260 (1988) 1429-1433
    • (1988) JAMA , vol.260 , pp. 1429-1433
    • Stamm, W.E.1    Handsfield, H.H.2    Rompalo, A.M.3    Ashley, R.L.4    Roberts, P.L.5    Corey, L.6
  • 39
    • 0035577406 scopus 로고    scopus 로고
    • Factors associated with acquisition of, or persistent colonization by, vaginal lactobacilli: role of hydrogen peroxide production
    • Vallor A.C., Antonio M.A., Hawes S.E., and Hillier S.L. Factors associated with acquisition of, or persistent colonization by, vaginal lactobacilli: role of hydrogen peroxide production. J Infect Dis 184 (2001) 1431-1436
    • (2001) J Infect Dis , vol.184 , pp. 1431-1436
    • Vallor, A.C.1    Antonio, M.A.2    Hawes, S.E.3    Hillier, S.L.4
  • 40
    • 30744457330 scopus 로고    scopus 로고
    • Ulcerative proctitis in men who have sex with men: an emerging outbreak
    • Williams D., and Churchill D. Ulcerative proctitis in men who have sex with men: an emerging outbreak. BMJ 332 (2006) 99-100
    • (2006) BMJ , vol.332 , pp. 99-100
    • Williams, D.1    Churchill, D.2
  • 41
    • 4544363784 scopus 로고    scopus 로고
    • Chlamydia trachomatis infection inhibits both bax and bak activation induced by staurosporine
    • Xiao Y., Zhong Y., Greene W., Dong F., and Zhong G. Chlamydia trachomatis infection inhibits both bax and bak activation induced by staurosporine. Infect Immunol 72 (2004) 5470-5474
    • (2004) Infect Immunol , vol.72 , pp. 5470-5474
    • Xiao, Y.1    Zhong, Y.2    Greene, W.3    Dong, F.4    Zhong, G.5
  • 42
    • 24644443874 scopus 로고    scopus 로고
    • Workplace and HIV-related sexual behaviours and perceptions among female migrant workers
    • Yang H., Li X., Stanton B., Fang X., Lin D., Mao R., et al. Workplace and HIV-related sexual behaviours and perceptions among female migrant workers. AIDS Care 17 (2005) 819-833
    • (2005) AIDS Care , vol.17 , pp. 819-833
    • Yang, H.1    Li, X.2    Stanton, B.3    Fang, X.4    Lin, D.5    Mao, R.6
  • 43
    • 33644519967 scopus 로고    scopus 로고
    • The evolution of peptide deformylase as a target: contribution of biochemistry, genetics and genomics
    • Yuan Z., and White R.J. The evolution of peptide deformylase as a target: contribution of biochemistry, genetics and genomics. Biochem Pharmacol 71 (2006) 1042-1047
    • (2006) Biochem Pharmacol , vol.71 , pp. 1042-1047
    • Yuan, Z.1    White, R.J.2


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