Drugs in porphyria: From observation to a modern algorithm-based system for the prediction of porphyrogenicity

Pharmacology and Therapeutics

Volumn 132, Issue 2, 2011, Pages 158-169

  Hift, Richard J ^a   Thunell, Stig ^b   Brun, Atle ^c,d  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY OF BERGEN   (Norway)

Author keywords

Drug metabolism; Porphyria; Porphyrogenicity

Indexed keywords

1,4 DIHYDRO 2,4,6 TRIMETHYL 3,5 PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER; 5 AMINOLEVULINATE SYNTHASE; ALLYLISOPROPYLACETAMIDE; BARBITURIC ACID DERIVATIVE; CYTOCHROME P450; GRISEOFULVIN; HALOGENATED HYDROCARBON; HEME;

ALGORITHM; ARTICLE; BIOSYNTHESIS; DRUG METABOLISM; DRUG SAFETY; ENZYME INHIBITION; GENE INDUCTION; GENOTYPE PHENOTYPE CORRELATION; HETEROZYGOTE; HUMAN; NONHUMAN; PATHOGENESIS; PATHOGENICITY; PORPHYRIA; PREDICTION; PRIORITY JOURNAL; UPREGULATION;

EID: 80052315445     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2011.06.001     Document Type: Review

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