5-Aminolevulinic acid synthase: Mechanism, mutations and medicine

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1647, Issue 1-2, 2003, Pages 361-366

  Shoolingin Jordan, Peter M ^a   Al Daihan, Sooad ^a   Alexeev, Dmitriy ^b   Baxter, Robert L ^b   Bottomley, Sylvia S ^c   Kahari, I Donald ^a   Roy, Ipsita ^a   Sarwar, Muhammad ^a   Sawyer, Lindsay ^b   Wang, Shu Fen ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

5 Aminolevulinic acid synthase; ALAS 2; Erythroid 5 aminolevulinic acid synthase; Human heme biosynthesis; Modeling; Rhodobacter spheroides 5 aminolevulinic acid synthase; Substrate specificity; Vitamin B6 therapy; X linked sideroblastic anemia

Indexed keywords

5 AMINOLEVULINATE SYNTHASE; 5 AMINOLEVULINIC ACID(5 AMINO 4 OXOPENTANOATE); ALANINE; CARBOXYL GROUP; GLYCINE; PYRIDOXAL 5 PHOSPHATE; SERINE; SUCCINYL COENZYME A SYNTHETASE; THREONINE; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE;

CONFERENCE PAPER; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; ERYTHROCYTE; MUTATION; PRIORITY JOURNAL; RHODOBACTER SPHAEROIDES; SITE DIRECTED MUTAGENESIS; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; ERYTHROID PRECURSOR CELL; GENETICS; HUMAN; METABOLISM; STRUCTURE ACTIVITY RELATION;

RHODOBACTER;

5-AMINOLEVULINATE SYNTHETASE; ERYTHROID PROGENITOR CELLS; HUMANS; MODELS, MOLECULAR; MUTATION; RHODOBACTER SPHAEROIDES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0038650906     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-9639(03)00095-5     Document Type: Conference Paper

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