DHCR24 gene knockout mice demonstrate lethal dermopathy with differentiation and maturation defects in the epidermis

Journal of Investigative Dermatology

Volumn 126, Issue 3, 2006, Pages 638-647

  Mirza, Rusella ^a   Hayasaka, Shizu ^a   Takagishi, Yoshiko ^a   Kambe, Fukushi ^a   Ohmori, Sachiko ^a   Maki, Kazuko ^a   Yamamoto, Michiyo ^a   Murakami, Kohji ^b   Kaji, Takahide ^b   Zadworny, David ^a   Murata, Yoshiharu ^a   Seo, Hisao ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3BETA HYDROXYSTEROL DELTA24 REDUCTASE; CHOLESTEROL; CYTOKERATIN 14; DESMOSTEROL; FILAGGRIN; INVOLUCRIN; KERATIN; KERATOHYALIN; LORICRIN; STEROL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CAUSE OF DEATH; CELL DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; DESMOSTEROLOSIS; EPIDERMIS CELL; GENE DISRUPTION; GENE EXPRESSION; GENE TARGETING; HISTOLOGY; HYPERKERATOSIS; KERATINOCYTE; KNOCKOUT MOUSE; LETHALITY; MOUSE; MOVEMENT (PHYSIOLOGY); NONHUMAN; PLIABILITY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SKIN DISEASE; SKIN STRUCTURE; SKIN SURFACE; SKINFOLD THICKNESS; SUCKING; TISSUE DISTRIBUTION;

ANIMALS; APOPTOSIS; CAVEOLIN 1; CELL DIFFERENTIATION; CELL PROLIFERATION; CERAMIDES; CHOLESTEROL; DESMOSTEROL; FATTY ACIDS, NONESTERIFIED; IMMUNOHISTOCHEMISTRY; KERATINOCYTES; KERATINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; NERVE TISSUE PROTEINS; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PERMEABILITY; SKIN; SKIN DISEASES;

EID: 32844454617     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700111     Document Type: Article

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