메뉴 건너뛰기




Volumn 30, Issue 4, 2010, Pages 408-419

Abnormal TDP-43 expression is identified in the neocortex in cases of dementia pugilistica, but is mainly confined to the limbic system when identified in high and moderate stages of Alzheimer's disease

Author keywords

boxing; Dementia; frontotemporal; TDP 43; trauma

Indexed keywords

DNA BINDING PROTEIN; TRANSACTIVE RESPONSE DNA BINDING PROTEIN WITH A MOLECULAR WEIGHT OF 43 KDA; UNCLASSIFIED DRUG;

EID: 77954149731     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2009.01085.x     Document Type: Article
Times cited : (95)

References (49)
  • 1
    • 33749632259 scopus 로고    scopus 로고
    • Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • Neumann M, Sampathu DM, Kwong LK et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 2006 314 : 130 133.
    • (2006) Science , vol.314 , pp. 130-133
    • Neumann, M.1    Sampathu, D.M.2    Kwong, L.K.3
  • 2
    • 33750716074 scopus 로고    scopus 로고
    • TDP-43 is a component of ubiquitin positive tau negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • Arai T, Hasgawa M, Akiyama H et al. TDP-43 is a component of ubiquitin positive tau negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 2006 351 : 602 611.
    • (2006) Biochem Biophys Res Commun , vol.351 , pp. 602-611
    • Arai, T.1    Hasgawa, M.2    Akiyama, H.3
  • 3
    • 57049105123 scopus 로고    scopus 로고
    • Nomenclature for neuropathological subtypes of frontotemporal lobar degeneration: Consensus recommendations
    • Mackenzie I, Neumann M, Bigio E et al. Nomenclature for neuropathological subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathol 2009 117 : 15 18.
    • (2009) Acta Neuropathol , vol.117 , pp. 15-18
    • Mackenzie, I.1    Neumann, M.2    Bigio, E.3
  • 4
    • 36348972414 scopus 로고    scopus 로고
    • Concurrence of TDP-43, tau and synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies
    • Higashi S, Iseki E, Yamamato R et al. Concurrence of TDP-43, tau and synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies. Brain Res 2007 1184 : 284 294.
    • (2007) Brain Res , vol.1184 , pp. 284-294
    • Higashi, S.1    Iseki, E.2    Yamamato, R.3
  • 5
    • 43249094487 scopus 로고    scopus 로고
    • Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiological phenotype
    • Josephs K, Whitwell J, Knopman DS et al. Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiological phenotype. Neurol 2008 70 : 1850 1857.
    • (2008) Neurol , vol.70 , pp. 1850-1857
    • Josephs, K.1    Whitwell, J.2    Knopman, D.S.3
  • 6
    • 34547733547 scopus 로고    scopus 로고
    • Co-morbidity of TDP-43 proteinopathy in Lewy Body related diseases
    • Nakashima-Yasuda H, Uryu K, Robinson J et al. Co-morbidity of TDP-43 proteinopathy in Lewy Body related diseases. Acta Neuropathol 2007 114 : 221 229.
    • (2007) Acta Neuropathol , vol.114 , pp. 221-229
    • Nakashima-Yasuda, H.1    Uryu, K.2    Robinson, J.3
  • 7
    • 44649137415 scopus 로고    scopus 로고
    • Concomitant TAR-DNA-Binding Protein 43 pathology is present in Alzheimer disease and Corticobasal degeneration but not other tauopathies
    • Uryu K, Nakashima-Yasuda H, Forman M et al. Concomitant TAR-DNA-Binding Protein 43 pathology is present in Alzheimer disease and Corticobasal degeneration but not other tauopathies. J Neuropathol Exp Neurol 2008 67 : 555 564.
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 555-564
    • Uryu, K.1    Nakashima-Yasuda, H.2    Forman, M.3
  • 9
    • 77954831259 scopus 로고    scopus 로고
    • TAR DNA binding protein-43 (TDP-43) proteinopathy in association with progressive supranuclear palsy
    • Suppl
    • Massey L, Lashley T, O'Sullivan S et al. TAR DNA binding protein-43 (TDP-43) proteinopathy in association with progressive supranuclear palsy. Neuropathol Appl Neurobiol 2009 35 (Suppl 29.
    • (2009) Neuropathol Appl Neurobiol , vol.35 , pp. 29
    • Massey, L.1    Lashley, T.2    O'Sullivan, S.3
  • 10
    • 47949084000 scopus 로고    scopus 로고
    • Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer's Disease
    • Hu W, Josephs K, Knopman DS et al. Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer's Disease. Acta Neuropathol 2008 116 : 215 220.
    • (2008) Acta Neuropathol , vol.116 , pp. 215-220
    • Hu, W.1    Josephs, K.2    Knopman, D.S.3
  • 11
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 1991 82 : 239 259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 12
    • 47549094635 scopus 로고    scopus 로고
    • Staging of neurofibrillary pathology in Alzheimer's Disease. A study of the BrainNet consortium
    • Alafuzoff I, Parkkinen L, Al-Sarraj S et al. Staging of neurofibrillary pathology in Alzheimer's Disease. A study of the BrainNet consortium. Brain Pathol 2008 18 : 484 496.
    • (2008) Brain Pathol , vol.18 , pp. 484-496
    • Alafuzoff, I.1    Parkkinen, L.2    Al-Sarraj, S.3
  • 13
    • 34249949338 scopus 로고    scopus 로고
    • TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's Disease
    • Amador-Ortiz C, Lin W-G, Ahmed Z et al. TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's Disease. Ann Neurol 2007 61 : 435 445.
    • (2007) Ann Neurol , vol.61 , pp. 435-445
    • Amador-Ortiz, C.1    Lin, W.-G.2    Ahmed, Z.3
  • 14
    • 39749083266 scopus 로고    scopus 로고
    • TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system
    • Lee E, Lee V, Trojanowski J, Neumann M. TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system. Acta Neuropathol 2008 115 : 305 311.
    • (2008) Acta Neuropathol , vol.115 , pp. 305-311
    • Lee, E.1    Lee, V.2    Trojanowski, J.3    Neumann, M.4
  • 15
    • 33144489150 scopus 로고    scopus 로고
    • Diagnosis and management of dementia with Lewy Bodies. Third report of the DLB consortium
    • McKeith I, Dickson D, Lowe J et al. Diagnosis and management of dementia with Lewy Bodies. Third report of the DLB consortium. Neurology 2005 65 : 1863 1872.
    • (2005) Neurology , vol.65 , pp. 1863-1872
    • McKeith, I.1    Dickson, D.2    Lowe, J.3
  • 16
    • 59249085091 scopus 로고    scopus 로고
    • Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
    • Neumann M, Kwong L, Lee E et al. Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathol 2009 117 : 137 149.
    • (2009) Acta Neuropathol , vol.117 , pp. 137-149
    • Neumann, M.1    Kwong, L.2    Lee, E.3
  • 17
    • 33846076379 scopus 로고    scopus 로고
    • Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies
    • Sampathu D, Neumann M, Kwong L et al. Pathological heterogeneity of frontotemporal lobar degeneration with ubiquitin-positive inclusions delineated by ubiquitin immunohistochemistry and novel monoclonal antibodies. Am J Pathol 2006 169 : 1343 1352.
    • (2006) Am J Pathol , vol.169 , pp. 1343-1352
    • Sampathu, D.1    Neumann, M.2    Kwong, L.3
  • 18
    • 34447096691 scopus 로고    scopus 로고
    • Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: Consensus of the consortium for frontotemporal lobar degeneration
    • Cairns N, Bigio E, Mackenzie I et al. Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the consortium for frontotemporal lobar degeneration. Acta Neuropathol 2007 114 : 5 22.
    • (2007) Acta Neuropathol , vol.114 , pp. 5-22
    • Cairns, N.1    Bigio, E.2    Mackenzie, I.3
  • 19
    • 59249097160 scopus 로고    scopus 로고
    • Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies
    • Arai T, Mackenzie I, Hasegawa M et al. Phosphorylated TDP-43 in Alzheimer's disease and dementia with Lewy bodies. Acta Neuropathol 2009 117 : 125 136.
    • (2009) Acta Neuropathol , vol.117 , pp. 125-136
    • Arai, T.1    Mackenzie, I.2    Hasegawa, M.3
  • 20
    • 0030969902 scopus 로고    scopus 로고
    • First Alfred Meyer memorial lecture. Epileptic brain damage: A consequence and cause of seizures
    • Meldrum B. First Alfred Meyer memorial lecture. Epileptic brain damage: a consequence and cause of seizures. Neuropathol Appl Neurobiol 1997 23 : 185 202.
    • (1997) Neuropathol Appl Neurobiol , vol.23 , pp. 185-202
    • Meldrum, B.1
  • 21
    • 47949093588 scopus 로고    scopus 로고
    • Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases
    • Lin W-L, Dickson D. Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases. Acta Neuropathol 2008 116 : 205 213.
    • (2008) Acta Neuropathol , vol.116 , pp. 205-213
    • Lin, W.-L.1    Dickson, D.2
  • 22
    • 58149398638 scopus 로고    scopus 로고
    • Colocalization of transactivation-responsive DNA binding protein 43 and Huntingtin in inclusions of Huntington's Disease
    • Schwab C, Arai T, Hasegawa M, Yu S, McGeer P. Colocalization of transactivation-responsive DNA binding protein 43 and Huntingtin in inclusions of Huntington's Disease. J Neuropathol Exp Neurol 2008 67 : 1159 1165.
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 1159-1165
    • Schwab, C.1    Arai, T.2    Hasegawa, M.3    Yu, S.4    McGeer, P.5
  • 23
    • 0242441450 scopus 로고    scopus 로고
    • Medical and environmental risk factors for sporadic frontotemporal dementia: A retrospective case-control study
    • Rosso S, Landweer E-J, Houterman M et al. Medical and environmental risk factors for sporadic frontotemporal dementia: a retrospective case-control study. J Neurol Neurosurg Psychiatry 2003 74 : 1574 1576.
    • (2003) J Neurol Neurosurg Psychiatry , vol.74 , pp. 1574-1576
    • Rosso, S.1    Landweer, E.-J.2    Houterman, M.3
  • 25
    • 0024561396 scopus 로고
    • Boxing and the brain
    • Corsellis J. Boxing and the brain. Br Med J 1989 298 : 105 109.
    • (1989) Br Med J , vol.298 , pp. 105-109
    • Corsellis, J.1
  • 27
    • 33745925898 scopus 로고    scopus 로고
    • Association between recurrent concussion and late-life cognitive impairment in retired professional football players
    • Guskiewicz K, Marshall S, Bailes J et al. Association between recurrent concussion and late-life cognitive impairment in retired professional football players. Neurosurgery 2005 57 : 719 726.
    • (2005) Neurosurgery , vol.57 , pp. 719-726
    • Guskiewicz, K.1    Marshall, S.2    Bailes, J.3
  • 28
    • 21744449747 scopus 로고    scopus 로고
    • Chronic traumatic encephalopathy in a National Football League player
    • Omalu B, DeKotsky S, Minster R et al. Chronic traumatic encephalopathy in a National Football League player. Neurosurgery 2005 57 : 128 134.
    • (2005) Neurosurgery , vol.57 , pp. 128-134
    • Omalu, B.1    DeKotsky, S.2    Minster, R.3
  • 29
    • 35448965048 scopus 로고    scopus 로고
    • Dementia Pugilistica with clinical features of Alzheimer's Disease
    • Areza-Fegyveres R, Rosemberg S, Castro R et al. Dementia Pugilistica with clinical features of Alzheimer's Disease. Arq Neuropsiquiatr 2007 65 : 830 833.
    • (2007) Arq Neuropsiquiatr , vol.65 , pp. 830-833
    • Areza-Fegyveres, R.1    Rosemberg, S.2    Castro, R.3
  • 30
    • 0034963745 scopus 로고    scopus 로고
    • Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease
    • Schmidt M, Zhukareva V, Newell K et al. Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease. Acta Neuropathol 2001 101 : 518 524.
    • (2001) Acta Neuropathol , vol.101 , pp. 518-524
    • Schmidt, M.1    Zhukareva, V.2    Newell, K.3
  • 31
    • 0025784849 scopus 로고
    • Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid -protein and tau protein
    • Tokuda T, Ikeda S, Yanagisawa N et al. Re-examination of ex-boxers' brains using immunohistochemistry with antibodies to amyloid -protein and tau protein. Acta Neuropathol 1991 82 : 280 285.
    • (1991) Acta Neuropathol , vol.82 , pp. 280-285
    • Tokuda, T.1    Ikeda, S.2    Yanagisawa, N.3
  • 32
    • 0026454256 scopus 로고
    • Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases
    • Hof P, Bouras C, Buée L et al. Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. Acta Neuropathol 1992 85 : 23 30.
    • (1992) Acta Neuropathol , vol.85 , pp. 23-30
    • Hof, P.1    Bouras, C.2    Buée, L.3
  • 33
    • 68249157080 scopus 로고    scopus 로고
    • Chronic Traumatic Encephalopathy in atheletes; progressive tauopathy after repetitive head injury
    • McKee A, Cantu R, Nowinski C et al. Chronic Traumatic Encephalopathy in atheletes; progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol 2009 68 : 709 735.
    • (2009) J Neuropathol Exp Neurol , vol.68 , pp. 709-735
    • McKee, A.1    Cantu, R.2    Nowinski, C.3
  • 36
    • 56749098112 scopus 로고    scopus 로고
    • Enduring involvement of tau, β-amyloid, β-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonian-dementia complex of Guam (ALS/PDC)
    • Miklossy J, Steele J, Yu S et al. Enduring involvement of tau, β-amyloid, β-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonian-dementia complex of Guam (ALS/PDC). Acta Neuropathol 2008 116 : 625 637.
    • (2008) Acta Neuropathol , vol.116 , pp. 625-637
    • Miklossy, J.1    Steele, J.2    Yu, S.3
  • 37
    • 0027482350 scopus 로고
    • Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury
    • Gentleman S, Nash M, Sweeting C et al. Beta-amyloid precursor protein (beta APP) as a marker for axonal injury after head injury. Neurosci Lett 1993 160 : 139 144.
    • (1993) Neurosci Lett , vol.160 , pp. 139-144
    • Gentleman, S.1    Nash, M.2    Sweeting, C.3
  • 38
    • 58049221032 scopus 로고    scopus 로고
    • Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: Implications for TDP-43 in the physiological response to neuronal injury
    • Moisse K, Volkening K, Leystra-Lantz C et al. Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury. Brain Res 2009 1249 : 202 211.
    • (2009) Brain Res , vol.1249 , pp. 202-211
    • Moisse, K.1    Volkening, K.2    Leystra-Lantz, C.3
  • 39
    • 77954827612 scopus 로고    scopus 로고
    • TDP-43 inclusions do not protect motor neurons from sporadic ALS
    • Pamphlett R, Jew S. TDP-43 inclusions do not protect motor neurons from sporadic ALS. Acta Neuropathol 2009 35 : 222 225.
    • (2009) Acta Neuropathol , vol.35 , pp. 222-225
    • Pamphlett, R.1    Jew, S.2
  • 42
    • 0027282035 scopus 로고
    • Apolipoprotein E polymorphism and Alzheimer's disease
    • Poirier J, Davignon J, Bouthillier D et al. Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 1993 342 (8873 696.
    • (1993) Lancet , vol.342 , Issue.8873 , pp. 696
    • Poirier, J.1    Davignon, J.2    Bouthillier, D.3
  • 43
    • 0027407565 scopus 로고
    • Apolipoprotein E: High avidity binding to beta-amyloid and increased frequency of type 4 allele in late onset familial Alzheimer disease
    • Strittmatter W, Saunders A, Schmechel D et al. Apolipoprotein E: high avidity binding to beta-amyloid and increased frequency of type 4 allele in late onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993 90 : 1977 1981.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1977-1981
    • Strittmatter, W.1    Saunders, A.2    Schmechel, D.3
  • 44
    • 33748902278 scopus 로고    scopus 로고
    • Functional correlates of Apolipoprotein E genotype in Frontotemporal Lobar Degeneration
    • Borroni B, Perani D, Archetti S et al. Functional correlates of Apolipoprotein E genotype in Frontotemporal Lobar Degeneration. BMC Neurol 2006 6 : 31.
    • (2006) BMC Neurol , vol.6 , pp. 31
    • Borroni, B.1    Perani, D.2    Archetti, S.3
  • 45
    • 32344434738 scopus 로고    scopus 로고
    • The apolipoprotein E ε4 allele selectively increases the risk of frontotemporal lobar degeneration in males
    • Srinivasan R, Davidson Y, Gibbons L et al. The apolipoprotein E ε4 allele selectively increases the risk of frontotemporal lobar degeneration in males. J Neurol Neurosurg Psychiatry 2006 77 : 154 158.
    • (2006) J Neurol Neurosurg Psychiatry , vol.77 , pp. 154-158
    • Srinivasan, R.1    Davidson, Y.2    Gibbons, L.3
  • 46
    • 0030610527 scopus 로고    scopus 로고
    • The apolipoprotein E epsilon 4 allele frequency is normal in fronto-temporal dementia, but correlates with age at onset of disease
    • Minthon L, Hesse C, Sjogren M et al. The apolipoprotein E epsilon 4 allele frequency is normal in fronto-temporal dementia, but correlates with age at onset of disease. Neurosci Lett 1997 226 : 65 67.
    • (1997) Neurosci Lett , vol.226 , pp. 65-67
    • Minthon, L.1    Hesse, C.2    Sjogren, M.3
  • 47
    • 39749141572 scopus 로고    scopus 로고
    • A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series
    • Beck J, Rohrer J, Campbell T et al. A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series. Brain 2008 131 : 706 720.
    • (2008) Brain , vol.131 , pp. 706-720
    • Beck, J.1    Rohrer, J.2    Campbell, T.3
  • 48
    • 0036235384 scopus 로고    scopus 로고
    • Apolipoprotein E polymorphism in German patients with frontotemporal degeneration
    • Reimenschider M, Diehl J, Muller U et al. Apolipoprotein E polymorphism in German patients with frontotemporal degeneration. J Neurol Neurosurg Psychiatry 2002 72 : 639 643.
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 639-643
    • Reimenschider, M.1    Diehl, J.2    Muller, U.3
  • 49
    • 18544368239 scopus 로고    scopus 로고
    • Apolipoprotein E gene in frontotemporal dementia; an association study and meta-analysis
    • Verpillat P, Camuzat A, Hannequin D et al. Apolipoprotein E gene in frontotemporal dementia; an association study and meta-analysis. Eur J Hum Genet 2002 10 : 399 405.
    • (2002) Eur J Hum Genet , vol.10 , pp. 399-405
    • Verpillat, P.1    Camuzat, A.2    Hannequin, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.