2-(Naphthalene-1-yl)-6- Pyrrolidinyl-4-quinazolinone inhibits skin cancer M21 cell proliferation through aberrant expression of microtubules and the cell cycle

Journal of Pharmacology and Experimental Therapeutics

Volumn 338, Issue 3, 2011, Pages 942-951

  Wu, Yang C ^a   Hour, Mann J ^a   Leung, Wing C ^b   Wu, Chi Y ^c   Liu, Wen Z ^a   Chang, Yu H ^a   Lee, Hong Zin ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c Chang Hua Hospital   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

2 (NAPHTHALENE 1 YL) 6 PYRROLIDINYL 4 QUINAZOLINONE; ANTINEOPLASTIC AGENT; CASPASE; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; HL 66; UNCLASSIFIED DRUG; VINBLASTINE;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MICROTUBULE; MICROTUBULE ASSEMBLY; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SKIN CANCER;

ANNEXIN A5; ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CASPASES; CDC2 PROTEIN KINASE; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; COLORING AGENTS; CYCLIN B1; DNA, NEOPLASM; DRUG DESIGN; G2 PHASE; HUMANS; IMMUNOHISTOCHEMISTRY; MICROTUBULES; MITOSIS; MODELS, MOLECULAR; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; PYRROLIDINES; QUINAZOLINONES; SKIN NEOPLASMS; TRYPAN BLUE; TUBULIN; TUBULIN MODULATORS;

EID: 80052185681     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.110.176115     Document Type: Article

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