-
1
-
-
23644439784
-
Vascular complications in diabetes mellitus: the role of endothelial dysfunction
-
Schalkwijk, C. G. & Stehouwer, C. D. Vascular complications in diabetes mellitus: the role of endothelial dysfunction. Clin. Sci. (Lond)109, 143-159 (2005).
-
(2005)
Clin. Sci. (Lond)
, vol.109
, pp. 143-159
-
-
Schalkwijk, C.G.1
Stehouwer, C.D.2
-
2
-
-
70449458051
-
Oxidative stress, endothelial dysfunction and atherosclerosis
-
Victor, V. M. et al. Oxidative stress, endothelial dysfunction and atherosclerosis. Curr. Pharm. Des. 15, 2988-3002 (2009).
-
(2009)
Curr. Pharm. Des.
, vol.15
, pp. 2988-3002
-
-
Victor, V.M.1
-
3
-
-
0019888193
-
Isolation of methylglyoxal synthase from goat liver
-
Ray, S. & Ray, M. Isolation of methylglyoxal synthase from goat liver. J. Biol. Chem. 256, 6230-6233 (1981).
-
(1981)
J. Biol. Chem.
, vol.256
, pp. 6230-6233
-
-
Ray, S.1
Ray, M.2
-
4
-
-
0027396022
-
The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal
-
Phillips, S. A. & Thornalley, P. J. The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal. Eur. J. Biochem. 212, 101-105 (1993).
-
(1993)
Eur. J. Biochem.
, vol.212
, pp. 101-105
-
-
Phillips, S.A.1
Thornalley, P.J.2
-
5
-
-
0033571012
-
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose
-
Thornalley, P. J., Langborg, A. & Minhas, H. S. Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose. Biochem. J. 344Pt 1, 109-116 (1999).
-
(1999)
Biochem. J
, vol.344
, Issue.Pt1
, pp. 109-116
-
-
Thornalley, P.J.1
Langborg, A.2
Minhas, H.S.3
-
6
-
-
0021323247
-
The metabolism of acetone in rat
-
Casazza, J. P., Felver, M. E. & Veech, R. L. The metabolism of acetone in rat. J. Biol. Chem. 259, 231-236 (1984).
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 231-236
-
-
Casazza, J.P.1
Felver, M.E.2
Veech, R.L.3
-
7
-
-
0038549049
-
Physiological and pathological implications of semicarbazide-sensitive amine oxidase
-
Yu, P. H., Wright, S., Fan, E. H., Lun, Z. R. & Gubisne-Harberle, D. Physiological and pathological implications of semicarbazide-sensitive amine oxidase. Biochim. Biophys. Acta1647, 193-199 (2003).
-
(2003)
Biochim. Biophys. Acta
, vol.1647
, pp. 193-199
-
-
Yu, P.H.1
Wright, S.2
Fan, E.H.3
Lun, Z.R.4
Gubisne-Harberle, D.5
-
8
-
-
0030919275
-
N-epsilon-(carboxyethyl) lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins
-
Ahmed, M. U., Brinkmann Frye, E., Degenhardt, T. P., Thorpe, S. R. & Baynes, J. W. N-epsilon-(carboxyethyl) lysine, a product of the chemical modification of proteins by methylglyoxal, increases with age in human lens proteins. Biochem. J. 324(Pt 2), 565-570 (1997).
-
(1997)
Biochem. J.
, vol.324
, Issue.Pt2
, pp. 565-570
-
-
Ahmed, M.U.1
Brinkmann Frye, E.2
Degenhardt, T.P.3
Thorpe, S.R.4
Baynes, J.W.5
-
9
-
-
0028453652
-
Lilly Lecture 1993. Glycation and diabetic complications
-
Brownlee, M. Lilly Lecture 1993. Glycation and diabetic complications. Diabetes43, 836-841 (1994).
-
(1994)
Diabetes
, vol.43
, pp. 836-841
-
-
Brownlee, M.1
-
10
-
-
0346788872
-
Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus
-
Bourajjaj, M., Stehouwer, C. D., van Hinsbergh, V. W. & Schalkwijk, C. G. Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus. Biochem. Soc. Trans. 31, 1400-1402 (2003).
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 1400-1402
-
-
Bourajjaj, M.1
Stehouwer, C.D.2
van Hinsbergh, V.W.3
Schalkwijk, C.G.4
-
11
-
-
0348049805
-
Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats
-
Karachalias, N., Babaei-Jadidi, R., Ahmed, N. & Thornalley, P. J. Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats. Biochem. Soc. Trans. 31, 1423-1425 (2003).
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 1423-1425
-
-
Karachalias, N.1
Babaei-Jadidi, R.2
Ahmed, N.3
Thornalley, P.J.4
-
12
-
-
0030763201
-
Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging
-
Schleicher, E. D., Wagner, E. & Nerlich, A. G. Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging. J. Clin. Invest. 99, 457-468 (1997).
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 457-468
-
-
Schleicher, E.D.1
Wagner, E.2
Nerlich, A.G.3
-
13
-
-
0037302018
-
Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes
-
Kilhovd, B. K. et al. Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes. Metabolism52, 163-167 (2003).
-
(2003)
Metabolism
, vol.52
, pp. 163-167
-
-
Kilhovd, B.K.1
-
14
-
-
0032032578
-
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis
-
Shinohara, M. et al. Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis. J. Clin. Invest. 101, 1142-1147 (1998).
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1142-1147
-
-
Shinohara, M.1
-
15
-
-
33644667584
-
Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress
-
Beisswenger, P. J. et al. Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress. Diabetes54, 3274-3281 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 3274-3281
-
-
Beisswenger, P.J.1
-
16
-
-
23344435471
-
Vascular methylglyoxal metabolism and the development of hypertension
-
Wang, X., Desai, K., Chang, T. & Wu, L. Vascular methylglyoxal metabolism and the development of hypertension. J. Hypertens. 23, 1565-1573 (2005).
-
(2005)
J. Hypertens.
, vol.23
, pp. 1565-1573
-
-
Wang, X.1
Desai, K.2
Chang, T.3
Wu, L.4
-
17
-
-
10644223132
-
Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats
-
Wang, X., Desai, K., Clausen, J. T. & Wu, L. Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats. Kidney Int. 66, 2315-2321 (2004).
-
(2004)
Kidney Int.
, vol.66
, pp. 2315-2321
-
-
Wang, X.1
Desai, K.2
Clausen, J.T.3
Wu, L.4
-
18
-
-
23844502010
-
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins
-
Zeng, J. & Davies, M. J. Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins. Chem. Res. Toxicol. 18, 1232-1241 (2005).
-
(2005)
Chem. Res. Toxicol.
, vol.18
, pp. 1232-1241
-
-
Zeng, J.1
Davies, M.J.2
-
19
-
-
0142124840
-
Glyoxal and methylglyoxal levels in diabetic patients: quantitative determination by a new GC/MS method
-
Lapolla, A. et al. Glyoxal and methylglyoxal levels in diabetic patients: quantitative determination by a new GC/MS method. Clin. Chem. Lab. Med. 41, 1166-1173 (2003).
-
(2003)
Clin. Chem. Lab. Med.
, vol.41
, pp. 1166-1173
-
-
Lapolla, A.1
-
20
-
-
79651470951
-
Increased plasma methylglyoxal level, inflammation, and vascular endothelial dysfunction in diabetic nephropathy
-
Meng, Q. H. et al. Increased plasma methylglyoxal level, inflammation, and vascular endothelial dysfunction in diabetic nephropathy. Clin. Biochem. 44, 307-311 (2011).
-
(2011)
Clin. Biochem.
, vol.44
, pp. 307-311
-
-
Meng, Q.H.1
-
21
-
-
3042841941
-
Methylglyoxal induces apoptosis through activation of p38 MAPK in rat Schwann cells
-
Fukunaga, M. et al. Methylglyoxal induces apoptosis through activation of p38 MAPK in rat Schwann cells. Biochem. Biophys. Res. Commun. 320, 689-695 (2004).
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 689-695
-
-
Fukunaga, M.1
-
22
-
-
1542333426
-
Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes
-
Kim, J., Son, J. W., Lee, J. A., Oh, Y. S. & Shinn, S. H. Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes. J. Korean Med. Sci. 19, 95-100 (2004).
-
(2004)
J. Korean Med. Sci.
, vol.19
, pp. 95-100
-
-
Kim, J.1
Son, J.W.2
Lee, J.A.3
Oh, Y.S.4
Shinn, S.H.5
-
23
-
-
0035399660
-
Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells
-
Akhand, A. A. et al. Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells. Free Radic. Biol. Med. 31, 20-30 (2001).
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 20-30
-
-
Akhand, A.A.1
-
24
-
-
36249008638
-
Ras activation modulates methylglyoxal-induced mesangial cell apoptosis through superoxide production
-
Huang, W. J. et al. Ras activation modulates methylglyoxal-induced mesangial cell apoptosis through superoxide production. Ren. Fail. 29, 911-921 (2007).
-
(2007)
Ren. Fail.
, vol.29
, pp. 911-921
-
-
Huang, W.J.1
-
25
-
-
0035882511
-
Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process
-
Du, J. et al. Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process. Free Radic. Biol. Med. 31, 469-478 (2001).
-
(2001)
Free Radic. Biol. Med.
, vol.31
, pp. 469-478
-
-
Du, J.1
-
26
-
-
0141861127
-
Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury
-
Amicarelli, F. et al. Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury. Free Radic. Biol. Med. 35, 856-871 (2003).
-
(2003)
Free Radic. Biol. Med.
, vol.35
, pp. 856-871
-
-
Amicarelli, F.1
-
27
-
-
21744448064
-
Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds
-
Berlanga, J. et al. Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds. Clin. Sci. (Lond)109, 83-95 (2005).
-
(2005)
Clin. Sci. (Lond)
, vol.109
, pp. 83-95
-
-
Berlanga, J.1
-
28
-
-
34547589578
-
DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists
-
Huang da, W. et al. DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res. 35, W169-175 (2007).
-
(2007)
Nucleic Acids Res.
, vol.35
-
-
da Huang, W.1
-
29
-
-
77955981191
-
Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure
-
Ogawa, S. et al. Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure. Hypertension56, 471-476 (2010).
-
(2010)
Hypertension
, vol.56
, pp. 471-476
-
-
Ogawa, S.1
-
30
-
-
0347419280
-
alpha-oxoaldehyde metabolism and diabetic complications
-
Beisswenger, P. J., Howell, S. K., Nelson, R. G., Mauer, M. & Szwergold, B. S. alpha-oxoaldehyde metabolism and diabetic complications. Biochem. Soc. Trans. 31, 1358-1363 (2003).
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 1358-1363
-
-
Beisswenger, P.J.1
Howell, S.K.2
Nelson, R.G.3
Mauer, M.4
Szwergold, B.S.5
-
31
-
-
71649103265
-
Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells
-
Abe, M. et al. Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells. Free Radic. Res. 44, 101-107 (2010).
-
(2010)
Free Radic. Res.
, vol.44
, pp. 101-107
-
-
Abe, M.1
-
32
-
-
0344826549
-
Hyper-vascular change and formation of advanced glycation endproducts in the peritoneum caused by methylglyoxal and the effect of an anti-oxidant, sodium sulfite
-
Nakayama, M., Sakai, A., Numata, M. & Hosoya, T. Hyper-vascular change and formation of advanced glycation endproducts in the peritoneum caused by methylglyoxal and the effect of an anti-oxidant, sodium sulfite. Am. J. Nephrol. 23, 390-394 (2003).
-
(2003)
Am. J. Nephrol.
, vol.23
, pp. 390-394
-
-
Nakayama, M.1
Sakai, A.2
Numata, M.3
Hosoya, T.4
-
33
-
-
23344435471
-
Vascular methylglyoxal metabolism and the development of hypertension
-
Wang, X. X., Desai, K., Chang, T. J. & Wu, L. Y. Vascular methylglyoxal metabolism and the development of hypertension. J. Hypertens. 23, 1565-1573 (2005).
-
(2005)
J. Hypertens.
, vol.23
, pp. 1565-1573
-
-
Wang, X.X.1
Desai, K.2
Chang, T.J.3
Wu, L.Y.4
-
34
-
-
78049261480
-
RTN3 and RTN4: Candidate modulators in vascular cell apoptosis and atherosclerosis
-
Chen, Y., Zhao, S. & Xiang, R. RTN3 and RTN4: Candidate modulators in vascular cell apoptosis and atherosclerosis. J. Cell. Biochem. 111, 797-800.
-
J. Cell. Biochem
, vol.111
, pp. 797-800
-
-
Chen, Y.1
Zhao, S.2
Xiang, R.3
-
35
-
-
29444452877
-
Platelet-derived growth factor-BB transactivates the fibroblast growth factor receptor to induce proliferation in human smooth muscle cells
-
Millette, E., Rauch, B. H., Kenagy, R. D., Daum, G. & Clowes, A. W. Platelet-derived growth factor-BB transactivates the fibroblast growth factor receptor to induce proliferation in human smooth muscle cells. Trends Cardiovasc. Med. 16, 25-28 (2006).
-
(2006)
Trends Cardiovasc. Med.
, vol.16
, pp. 25-28
-
-
Millette, E.1
Rauch, B.H.2
Kenagy, R.D.3
Daum, G.4
Clowes, A.W.5
-
36
-
-
58549115679
-
Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression
-
Wagsater, D., Zhu, C., Bjorck, H. M. & Eriksson, P. Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression. Atherosclerosis202, 415-423 (2009).
-
(2009)
Atherosclerosis
, vol.202
, pp. 415-423
-
-
Wagsater, D.1
Zhu, C.2
Bjorck, H.M.3
Eriksson, P.4
-
37
-
-
77955296455
-
The interaction between coagulation factor 2 receptor and interleukin 6 haplotypes increases the risk of myocardial infarction in men
-
Gigante, B., Bennet, A. M., Leander, K., Vikstrom, M. & de Faire, U. The interaction between coagulation factor 2 receptor and interleukin 6 haplotypes increases the risk of myocardial infarction in men. PLoS One5 (2010).
-
(2010)
PLoS One5
-
-
Gigante, B.1
Bennet, A.M.2
Leander, K.3
Vikstrom, M.4
de Faire, U.5
-
38
-
-
18444380862
-
Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys
-
Rosenberger, C. et al. Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. J. Am. Soc. Nephrol. 13, 1721-1732 (2002).
-
(2002)
J. Am. Soc. Nephrol.
, vol.13
, pp. 1721-1732
-
-
Rosenberger, C.1
-
39
-
-
65749105590
-
Liposomal formulation of alpha-tocopheryl maleamide: in vitro and in vivo toxicological profile and anticancer effect against spontaneous breast carcinomas in mice
-
Turanek, J. et al. Liposomal formulation of alpha-tocopheryl maleamide: in vitro and in vivo toxicological profile and anticancer effect against spontaneous breast carcinomas in mice. Toxicol. Appl. Pharmacol. 237, 249-257 (2009).
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.237
, pp. 249-257
-
-
Turanek, J.1
-
40
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
Forsythe, J. A. et al. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol. Cell. Biol. 16, 4604-4613 (1996).
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
-
41
-
-
0041874886
-
The CC chemokine CCL20 and its receptor CCR6
-
Schutyser, E., Struyf, S. & van Damme, J. The CC chemokine CCL20 and its receptor CCR6. Cytokine Growth Factor Rev. 14, 409-426 (2003).
-
(2003)
Cytokine Growth Factor Rev.
, vol.14
, pp. 409-426
-
-
Schutyser, E.1
Struyf, S.2
van Damme, J.3
-
42
-
-
64249155625
-
Macrophage inflammatory protein-3alpha plays a key role in the inflammatory cascade in rat focal cerebral ischemia
-
Terao, Y. et al. Macrophage inflammatory protein-3alpha plays a key role in the inflammatory cascade in rat focal cerebral ischemia. Neurosci. Res. 64, 75-82 (2009).
-
(2009)
Neurosci. Res.
, vol.64
, pp. 75-82
-
-
Terao, Y.1
-
43
-
-
79951697288
-
Toxicologic evaluation of bacterial synthesized cellulose in endothelial cells and animals
-
Jeong, S. I. et al. Toxicologic evaluation of bacterial synthesized cellulose in endothelial cells and animals. Mol. Cell. Toxicol. 6, 373-380 (2010).
-
(2010)
Mol. Cell. Toxicol.
, vol.6
, pp. 373-380
-
-
Jeong, S.I.1
-
44
-
-
78751688533
-
Identification of atherosclerosis related gene expression profiles by treatment of benzo(a) pyrene in human umbilical vein endothelial cells
-
Lee, S. H. et al. Identification of atherosclerosis related gene expression profiles by treatment of benzo(a) pyrene in human umbilical vein endothelial cells. Mol. Cell. Toxicol. 5, 113-119 (2009).
-
(2009)
Mol. Cell. Toxicol.
, vol.5
, pp. 113-119
-
-
Lee, S.H.1
-
45
-
-
77956572798
-
Acrolein induces adaptive response through upregulate of HO-1 via activation of Nrf2 in RAW 264.7 macrophage
-
Lee, N. J., Lee, S. E., Lee, S. H., Ryu, D. S. & Park, Y. S. Acrolein induces adaptive response through upregulate of HO-1 via activation of Nrf2 in RAW 264. 7 macrophage. Mol. Cell. Toxicol. 5, 230-236 (2009).
-
(2009)
Mol. Cell. Toxicol.
, vol.5
, pp. 230-236
-
-
Lee, N.J.1
Lee, S.E.2
Lee, S.H.3
Ryu, D.S.4
Park, Y.S.5
|