메뉴 건너뛰기




Volumn 44, Issue 4, 2011, Pages 307-311

Increased plasma methylglyoxal level, inflammation, and vascular endothelial dysfunction in diabetic nephropathy

Author keywords

Adhesion molecules; Cytokines; Diabetes; Diabetic; Methylglyoxal; Nephropathy

Indexed keywords

ALBUMIN; CELL ADHESION MOLECULE; CREATININE; CYTOKINE; GLUCOSE; HEMOGLOBIN A1C; INTERLEUKIN 6; METHYLGLYOXAL; TUMOR NECROSIS FACTOR ALPHA;

EID: 79651470951     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2010.11.004     Document Type: Article
Times cited : (120)

References (41)
  • 1
    • 54349117353 scopus 로고    scopus 로고
    • Clinical practice guidelines for the prevention and management of diabetes in Canada
    • Canadian Diabetes Association
    • Clinical practice guidelines for the prevention and management of diabetes in Canada. Can. J. Diab. 2008, 32:S1-S201. Canadian Diabetes Association.
    • (2008) Can. J. Diab. , vol.32
  • 2
    • 3042856282 scopus 로고    scopus 로고
    • Very low levels of microalbuminuria are associated with increased risk of coronary heart disease and death independently of renal function, hypertension, and diabetes
    • Klausen K., Borch-Johnsen K., Feldt-Rasmussen B., et al. Very low levels of microalbuminuria are associated with increased risk of coronary heart disease and death independently of renal function, hypertension, and diabetes. Circulation 2004, 110:32-35.
    • (2004) Circulation , vol.110 , pp. 32-35
    • Klausen, K.1    Borch-Johnsen, K.2    Feldt-Rasmussen, B.3
  • 3
    • 0032703938 scopus 로고    scopus 로고
    • Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications
    • Kalapos M.P. Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications. Toxicol. Lett. 1999, 110:145-175.
    • (1999) Toxicol. Lett. , vol.110 , pp. 145-175
    • Kalapos, M.P.1
  • 5
    • 0032939905 scopus 로고    scopus 로고
    • MG level was highly elevated in diabetic patients compared with the normal controls
    • Beisswenger P.J., Howell S.K., Touchette A.D., Lal S., Szwergold B.S. MG level was highly elevated in diabetic patients compared with the normal controls. Diabetes 1999, 48:198-202.
    • (1999) Diabetes , vol.48 , pp. 198-202
    • Beisswenger, P.J.1    Howell, S.K.2    Touchette, A.D.3    Lal, S.4    Szwergold, B.S.5
  • 6
    • 0028292698 scopus 로고
    • Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications
    • McLellan A.C., Thornalley P.J., Benn J., Sonksen P.H. Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications. Clin. Sci. (Lond.) 1994, 87:21-29.
    • (1994) Clin. Sci. (Lond.) , vol.87 , pp. 21-29
    • McLellan, A.C.1    Thornalley, P.J.2    Benn, J.3    Sonksen, P.H.4
  • 7
    • 35248894440 scopus 로고    scopus 로고
    • Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus
    • Wang H., Meng Q.H., Gordon J.R., Khandwala H., Wu L. Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus. Clin. Biochem. 2007, 40:1232-1239.
    • (2007) Clin. Biochem. , vol.40 , pp. 1232-1239
    • Wang, H.1    Meng, Q.H.2    Gordon, J.R.3    Khandwala, H.4    Wu, L.5
  • 8
    • 21244463560 scopus 로고    scopus 로고
    • Evaluation of glyoxal and methylglyoxal levels in uremic patients under peritoneal dialysis
    • Lapolla A., Flamini R., Lupo A., et al. Evaluation of glyoxal and methylglyoxal levels in uremic patients under peritoneal dialysis. Ann. NY Acad. Sci. 2005, 1043:217-224.
    • (2005) Ann. NY Acad. Sci. , vol.1043 , pp. 217-224
    • Lapolla, A.1    Flamini, R.2    Lupo, A.3
  • 9
    • 10644223132 scopus 로고    scopus 로고
    • Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats
    • Wang X., Desai K., Clausen J.T., Wu L. Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats. Kidney Int. 2004, 66:2315-2321.
    • (2004) Kidney Int. , vol.66 , pp. 2315-2321
    • Wang, X.1    Desai, K.2    Clausen, J.T.3    Wu, L.4
  • 10
    • 25844476029 scopus 로고    scopus 로고
    • Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy
    • Pedchenko V.K., Chetyrkin S.V., Chuang P., et al. Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy. Diabetes 2005, 54:2952-2960.
    • (2005) Diabetes , vol.54 , pp. 2952-2960
    • Pedchenko, V.K.1    Chetyrkin, S.V.2    Chuang, P.3
  • 13
    • 33644755633 scopus 로고    scopus 로고
    • Interleukin-6 and diabetes: the good, the bad, or the indifferent?
    • Kristiansen O.P., Mandrup-Poulsen T. Interleukin-6 and diabetes: the good, the bad, or the indifferent?. Diabetes 2005, 54:S114-S124.
    • (2005) Diabetes , vol.54
    • Kristiansen, O.P.1    Mandrup-Poulsen, T.2
  • 14
    • 1442275317 scopus 로고    scopus 로고
    • Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes
    • Pickup J.C. Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diab. Care 2004, 27:813-823.
    • (2004) Diab. Care , vol.27 , pp. 813-823
    • Pickup, J.C.1
  • 15
    • 21744448064 scopus 로고    scopus 로고
    • Methylglyoxal administration induces diabetes-like microvascular changes
    • Berlanga J., Cibrian D., Guillen I., et al. Methylglyoxal administration induces diabetes-like microvascular changes. Clin. Sci. (Lond.) 2005, 109:83-95.
    • (2005) Clin. Sci. (Lond.) , vol.109 , pp. 83-95
    • Berlanga, J.1    Cibrian, D.2    Guillen, I.3
  • 17
    • 77950459927 scopus 로고    scopus 로고
    • Aberrant cytokines/chemokines production correlate with proteinuria in patients with overt diabetic nephropathy
    • Wu C.C., Chen J.S., Lu K.C., et al. Aberrant cytokines/chemokines production correlate with proteinuria in patients with overt diabetic nephropathy. Clin. Chim. Acta 2010, 411:700-704.
    • (2010) Clin. Chim. Acta , vol.411 , pp. 700-704
    • Wu, C.C.1    Chen, J.S.2    Lu, K.C.3
  • 18
    • 69949093803 scopus 로고    scopus 로고
    • Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications
    • Goldberg R.B. Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications. J. Clin. Endocrinol. Metab. 2009, 94:3171-3182.
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 3171-3182
    • Goldberg, R.B.1
  • 19
    • 56949105387 scopus 로고    scopus 로고
    • Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats
    • Ko G.J., Kang Y.S., Han S.Y., et al. Pioglitazone attenuates diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. Nephrol. Dial. Transplant. 2008, 23:2750-2760.
    • (2008) Nephrol. Dial. Transplant. , vol.23 , pp. 2750-2760
    • Ko, G.J.1    Kang, Y.S.2    Han, S.Y.3
  • 20
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002, 420:868-874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 21
    • 33745275550 scopus 로고    scopus 로고
    • Glycaemic control, markers of endothelial cell activation and oxidative stress in children with type 1 diabetes mellitus
    • Seckin D., Ilhan N., Ilhan N., Ertugrul S. Glycaemic control, markers of endothelial cell activation and oxidative stress in children with type 1 diabetes mellitus. Diab. Res. Clin. Pract. 2006, 73:191-197.
    • (2006) Diab. Res. Clin. Pract. , vol.73 , pp. 191-197
    • Seckin, D.1    Ilhan, N.2    Ilhan, N.3    Ertugrul, S.4
  • 22
    • 33747049210 scopus 로고    scopus 로고
    • Glucose ingestion induces an increase in intranuclear nuclear factor kappaB, a fall in cellular inhibitor kappaB, and an increase in tumor necrosis factor alpha messenger RNA by mononuclear cells in healthy human subjects
    • Aljada A., Friedman J., Ghanim H., et al. Glucose ingestion induces an increase in intranuclear nuclear factor kappaB, a fall in cellular inhibitor kappaB, and an increase in tumor necrosis factor alpha messenger RNA by mononuclear cells in healthy human subjects. Metabolism 2006, 55:1177-1185.
    • (2006) Metabolism , vol.55 , pp. 1177-1185
    • Aljada, A.1    Friedman, J.2    Ghanim, H.3
  • 23
    • 18844405709 scopus 로고    scopus 로고
    • Effect of intensive glycemic control on levels of markers of inflammation in type 1 diabetes mellitus in the diabetes control and complications trial
    • Schaumberg D.A., Glynn R.J., Jenkins A.J., et al. Effect of intensive glycemic control on levels of markers of inflammation in type 1 diabetes mellitus in the diabetes control and complications trial. Circulation 2005, 111:2446-2453.
    • (2005) Circulation , vol.111 , pp. 2446-2453
    • Schaumberg, D.A.1    Glynn, R.J.2    Jenkins, A.J.3
  • 24
    • 64349120378 scopus 로고    scopus 로고
    • Inflammation and progressive nephropathy in type 1 diabetes in the diabetes control and complications trial
    • Lin J., Glynn R.J., Rifai N., et al. Inflammation and progressive nephropathy in type 1 diabetes in the diabetes control and complications trial. Diab. Care 2008, 31:2338-2343.
    • (2008) Diab. Care , vol.31 , pp. 2338-2343
    • Lin, J.1    Glynn, R.J.2    Rifai, N.3
  • 25
    • 56749162146 scopus 로고    scopus 로고
    • Endothelial dysfunction and inflammation predict development of diabetic nephropathy in the Irbesartan in patients with type 2 diabetes and microalbuminuria (IRMA 2) study
    • Persson F., Rossing P., Hovind P., et al. Endothelial dysfunction and inflammation predict development of diabetic nephropathy in the Irbesartan in patients with type 2 diabetes and microalbuminuria (IRMA 2) study. Scand. J. Clin. Lab. Invest. 2008, 68(8):731-738.
    • (2008) Scand. J. Clin. Lab. Invest. , vol.68 , Issue.8 , pp. 731-738
    • Persson, F.1    Rossing, P.2    Hovind, P.3
  • 26
    • 34948816643 scopus 로고    scopus 로고
    • Plasma methylglyoxal and glyoxal are elevated and related to early membrane alteration in young, complication-free patients with type 1 diabetes
    • Han Y., Randell E., Vasdev S., et al. Plasma methylglyoxal and glyoxal are elevated and related to early membrane alteration in young, complication-free patients with type 1 diabetes. Mol. Cell. Biochem. 2007, 305:123-131.
    • (2007) Mol. Cell. Biochem. , vol.305 , pp. 123-131
    • Han, Y.1    Randell, E.2    Vasdev, S.3
  • 27
    • 63649138667 scopus 로고    scopus 로고
    • Plasma advanced glycation endproduct, methylglyoxal-derived hydroimidazolone is elevated in young, complication-free patients with type 1 diabetes
    • Han Y., Randell E., Vasdev S., et al. Plasma advanced glycation endproduct, methylglyoxal-derived hydroimidazolone is elevated in young, complication-free patients with type 1 diabetes. Clin. Biochem. 2009, 42:562-569.
    • (2009) Clin. Biochem. , vol.42 , pp. 562-569
    • Han, Y.1    Randell, E.2    Vasdev, S.3
  • 28
    • 0041859310 scopus 로고    scopus 로고
    • Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients
    • Uribarri J., Peppa M., Cai W., et al. Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients. Am. J. Kidney Dis. 2003, 42:532-538.
    • (2003) Am. J. Kidney Dis. , vol.42 , pp. 532-538
    • Uribarri, J.1    Peppa, M.2    Cai, W.3
  • 30
    • 0036084953 scopus 로고    scopus 로고
    • Alterations in renal mitochondrial respiration in response to the reactive oxoaldehyde methylglyoxal
    • Rosca M.G., Monnier V.M., Szweda L.I., Weiss M.F. Alterations in renal mitochondrial respiration in response to the reactive oxoaldehyde methylglyoxal. Am. J. Physiol. Ren. Physiol. 2002, 283:F52-F59.
    • (2002) Am. J. Physiol. Ren. Physiol. , vol.283
    • Rosca, M.G.1    Monnier, V.M.2    Szweda, L.I.3    Weiss, M.F.4
  • 31
    • 22344442393 scopus 로고    scopus 로고
    • Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation
    • Rosca M.G., Mustata T.G., Kinter M.T., et al. Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation. Am. J. Physiol. Ren. Physiol. 2005, 289:F420-F430.
    • (2005) Am. J. Physiol. Ren. Physiol. , vol.289
    • Rosca, M.G.1    Mustata, T.G.2    Kinter, M.T.3
  • 32
    • 12244312488 scopus 로고    scopus 로고
    • Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells
    • Liu B.F., Miyata S., Hirota Y., et al. Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells. Kidney Int. 2003, 63:947-957.
    • (2003) Kidney Int. , vol.63 , pp. 947-957
    • Liu, B.F.1    Miyata, S.2    Hirota, Y.3
  • 33
    • 77950898257 scopus 로고    scopus 로고
    • The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature
    • Yan S.F., Ramasamy R., Schmidt A.M. The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature. Circ. Res. 2010, 106:842-853.
    • (2010) Circ. Res. , vol.106 , pp. 842-853
    • Yan, S.F.1    Ramasamy, R.2    Schmidt, A.M.3
  • 35
    • 42449128417 scopus 로고    scopus 로고
    • Influence of renal involvement on peripheral blood mononuclear cell expression behaviour of tumour necrosis factor-alpha and interleukin-6 in type 2 diabetic patients
    • Navarro J.F., Mora C., Gómez M., Muros M., López-Aguilar C., García J. Influence of renal involvement on peripheral blood mononuclear cell expression behaviour of tumour necrosis factor-alpha and interleukin-6 in type 2 diabetic patients. Nephrol. Dial. Transplant. 2008, 23:919-926.
    • (2008) Nephrol. Dial. Transplant. , vol.23 , pp. 919-926
    • Navarro, J.F.1    Mora, C.2    Gómez, M.3    Muros, M.4    López-Aguilar, C.5    García, J.6
  • 37
    • 0037180567 scopus 로고    scopus 로고
    • Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy
    • Vlassara H., Cai W., Crandall J., et al. Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy. Proc. Natl Acad. Sci. USA 2002, 99:15596-15601.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 15596-15601
    • Vlassara, H.1    Cai, W.2    Crandall, J.3
  • 38
    • 0042386773 scopus 로고    scopus 로고
    • Single exposure of mesothelial cells to glucose degradation products (GDPs) yields early advanced glycation end-products (AGEs) and a proinflammatory response
    • Welten A.G., Schalkwijk C.G., ter Wee P.M., Meijer S., van den Born J., Beelen R.J. Single exposure of mesothelial cells to glucose degradation products (GDPs) yields early advanced glycation end-products (AGEs) and a proinflammatory response. Perit. Dial. Int. 2003, 23:213-221.
    • (2003) Perit. Dial. Int. , vol.23 , pp. 213-221
    • Welten, A.G.1    Schalkwijk, C.G.2    ter Wee, P.M.3    Meijer, S.4    van den Born, J.5    Beelen, R.J.6
  • 39
    • 33644859602 scopus 로고    scopus 로고
    • Elevated markers of endothelial dysfunction predict type 2 diabetes mellitus in middle-aged men and women from the general population
    • Thorand B., Baumert J., Chambless L., et al. Elevated markers of endothelial dysfunction predict type 2 diabetes mellitus in middle-aged men and women from the general population. Arterioscler. Thromb. Vasc. Biol. 2006, 26:398-405.
    • (2006) Arterioscler. Thromb. Vasc. Biol. , vol.26 , pp. 398-405
    • Thorand, B.1    Baumert, J.2    Chambless, L.3
  • 40
    • 58149462019 scopus 로고    scopus 로고
    • Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly
    • Prospective Study of Pravastatin in Elderly at Risk Trial Study Group
    • Sattar N., Murray H.M., Welsh P., et al. Are elevated circulating intercellular adhesion molecule 1 levels more strongly predictive of diabetes than vascular risk? Outcome of a prospective study in the elderly. Diabetologia 2009, 52:235-239. Prospective Study of Pravastatin in Elderly at Risk Trial Study Group.
    • (2009) Diabetologia , vol.52 , pp. 235-239
    • Sattar, N.1    Murray, H.M.2    Welsh, P.3
  • 41
    • 45449083028 scopus 로고    scopus 로고
    • Serum levels of soluble form of receptor for advanced glycation end products (sRAGE) are positively associated with circulating AGEs and soluble form of VCAM-1 in patients with type 2 diabetes
    • Nakamura K., Yamagishi S., Adachi H., et al. Serum levels of soluble form of receptor for advanced glycation end products (sRAGE) are positively associated with circulating AGEs and soluble form of VCAM-1 in patients with type 2 diabetes. Microvasc. Res. 2008, 76:52-56.
    • (2008) Microvasc. Res. , vol.76 , pp. 52-56
    • Nakamura, K.1    Yamagishi, S.2    Adachi, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.