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Volumn 412, Issue 2, 2011, Pages 197-202

Role of S6K1 in regulation of SREBP1c expression in the liver

Author keywords

Hepatocytes; Lipid synthesis; S6K1; SREBP1c

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOVIRUS VECTOR; BRANCHED CHAIN AMINO ACID; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHOTRANSFERASE; RAPAMYCIN; S6 KINASE 1; SHORT HAIRPIN RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 80052031072     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.07.038     Document Type: Article
Times cited : (72)

References (30)
  • 1
    • 0034804783 scopus 로고    scopus 로고
    • Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes
    • Shimano H. Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes. Prog. Lipid Res. 2001, 40:439-452.
    • (2001) Prog. Lipid Res. , vol.40 , pp. 439-452
    • Shimano, H.1
  • 2
    • 0033636780 scopus 로고    scopus 로고
    • Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
    • Shimomura I., Matsuda M., Hammer R.E., Bashmakov Y., Brown M.S., Goldstein J.L. Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. Mol. Cell 2000, 6:77-86.
    • (2000) Mol. Cell , vol.6 , pp. 77-86
    • Shimomura, I.1    Matsuda, M.2    Hammer, R.E.3    Bashmakov, Y.4    Brown, M.S.5    Goldstein, J.L.6
  • 5
    • 0030907175 scopus 로고    scopus 로고
    • Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells
    • Shimano H., Horton J.D., Shimomura I., Hammer R.E., Brown M.S., Goldstein J.L. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. J. Clin. Invest. 1997, 99:846-854.
    • (1997) J. Clin. Invest. , vol.99 , pp. 846-854
    • Shimano, H.1    Horton, J.D.2    Shimomura, I.3    Hammer, R.E.4    Brown, M.S.5    Goldstein, J.L.6
  • 6
    • 38649116056 scopus 로고    scopus 로고
    • Selective versus total insulin resistance: a pathogenic paradox
    • Brown M.S., Goldstein J.L. Selective versus total insulin resistance: a pathogenic paradox. Cell Metab. 2008, 7:95-96.
    • (2008) Cell Metab. , vol.7 , pp. 95-96
    • Brown, M.S.1    Goldstein, J.L.2
  • 8
    • 0036260017 scopus 로고    scopus 로고
    • Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes
    • Matsumoto M., Ogawa W., Teshigawara K., Inoue H., Miyake K., Sakaue H., Kasuga M. Role of the insulin receptor substrate 1 and phosphatidylinositol 3-kinase signaling pathway in insulin-induced expression of sterol regulatory element binding protein 1c and glucokinase genes in rat hepatocytes. Diabetes 2002, 51:1672-1680.
    • (2002) Diabetes , vol.51 , pp. 1672-1680
    • Matsumoto, M.1    Ogawa, W.2    Teshigawara, K.3    Inoue, H.4    Miyake, K.5    Sakaue, H.6    Kasuga, M.7
  • 9
    • 0036853886 scopus 로고    scopus 로고
    • Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver
    • Miyake K., Ogawa W., Matsumoto M., Nakamura T., Sakaue H., Kasuga M. Hyperinsulinemia, glucose intolerance, and dyslipidemia induced by acute inhibition of phosphoinositide 3-kinase signaling in the liver. J. Clin. Invest. 2002, 110:1483-1491.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1483-1491
    • Miyake, K.1    Ogawa, W.2    Matsumoto, M.3    Nakamura, T.4    Sakaue, H.5    Kasuga, M.6
  • 10
    • 34249679614 scopus 로고    scopus 로고
    • MTOR complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer
    • Dann S.G., Selvaraj A., Thomas G. MTOR complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer. Trends Mol. Med. 2007, 13:252-259.
    • (2007) Trends Mol. Med. , vol.13 , pp. 252-259
    • Dann, S.G.1    Selvaraj, A.2    Thomas, G.3
  • 13
    • 77649264504 scopus 로고    scopus 로고
    • Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis
    • Li S., Brown M.S., Goldstein J.L. Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis. Proc. Natl. Acad. Sci. USA 2010, 107:3441-3446.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 3441-3446
    • Li, S.1    Brown, M.S.2    Goldstein, J.L.3
  • 14
    • 78650239404 scopus 로고    scopus 로고
    • Functions and regulation of the 70kDa ribosomal S6 kinases
    • Fenton T.R., Gout I.T. Functions and regulation of the 70kDa ribosomal S6 kinases. Int. J. Biochem. Cell Biol. 2011, 43:47-59.
    • (2011) Int. J. Biochem. Cell Biol. , vol.43 , pp. 47-59
    • Fenton, T.R.1    Gout, I.T.2
  • 15
    • 0027979778 scopus 로고
    • Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor α
    • Wu J.C., Merlino G., Fausto N. Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor α. Proc. Natl. Acad. Sci. USA 1994, 91:674-678.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 674-678
    • Wu, J.C.1    Merlino, G.2    Fausto, N.3
  • 20
    • 0032486268 scopus 로고    scopus 로고
    • Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
    • Hara K., Yonezawa K., Weng Q.P., Kozlowski M.T., Belham C., Avruch J. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J. Biol. Chem. 1998, 273:14484-14494.
    • (1998) J. Biol. Chem. , vol.273 , pp. 14484-14494
    • Hara, K.1    Yonezawa, K.2    Weng, Q.P.3    Kozlowski, M.T.4    Belham, C.5    Avruch, J.6
  • 21
    • 13244252424 scopus 로고    scopus 로고
    • Mechanisms regulating phosphoinositide 3-kinase signalling in insulin-sensitive tissues
    • Shepherd P.R. Mechanisms regulating phosphoinositide 3-kinase signalling in insulin-sensitive tissues. Acta Physiol. Scand. 2005, 183:3-12.
    • (2005) Acta Physiol. Scand. , vol.183 , pp. 3-12
    • Shepherd, P.R.1
  • 22
    • 0032514924 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region
    • Gout I., Minami T., Hara K., Tsujishita Y., Filonenko V., Waterfield M.D., Yonezawa K. Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich region. J. Biol. Chem. 1998, 273:30061-30064.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30061-30064
    • Gout, I.1    Minami, T.2    Hara, K.3    Tsujishita, Y.4    Filonenko, V.5    Waterfield, M.D.6    Yonezawa, K.7
  • 23
    • 14244256097 scopus 로고    scopus 로고
    • Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance
    • Khamzina L., Veilleux A., Bergeron S., Marette A. Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance. Endocrinology 2005, 146:1473-1481.
    • (2005) Endocrinology , vol.146 , pp. 1473-1481
    • Khamzina, L.1    Veilleux, A.2    Bergeron, S.3    Marette, A.4
  • 24
    • 57349116906 scopus 로고    scopus 로고
    • Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice
    • Miller A.M., Brestoff J.R., Phelps C.B., Berk E.Z., Reynolds T.H. Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008, 295:R1431-R1438.
    • (2008) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.295
    • Miller, A.M.1    Brestoff, J.R.2    Phelps, C.B.3    Berk, E.Z.4    Reynolds, T.H.5
  • 26
    • 0023904645 scopus 로고
    • Plasma amino acids and insulin levels in obesity: response to carbohydrate intake and tryptophan supplements
    • Caballero B., Finer N., Wurtman R.J. Plasma amino acids and insulin levels in obesity: response to carbohydrate intake and tryptophan supplements. Metabolism 1988, 37:672-676.
    • (1988) Metabolism , vol.37 , pp. 672-676
    • Caballero, B.1    Finer, N.2    Wurtman, R.J.3
  • 27
    • 6344226632 scopus 로고    scopus 로고
    • Amino acid metabolism in the Zucker diabetic fatty rat: effects of insulin resistance and of type 2 diabetes
    • Wijekoon E.P., Skinner C., Brosnan M.E., Brosnan J.T. Amino acid metabolism in the Zucker diabetic fatty rat: effects of insulin resistance and of type 2 diabetes. Can. J. Physiol. Pharmacol. 2004, 82:506-514.
    • (2004) Can. J. Physiol. Pharmacol. , vol.82 , pp. 506-514
    • Wijekoon, E.P.1    Skinner, C.2    Brosnan, M.E.3    Brosnan, J.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.