WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D, a natural compound found in Platycodon grandiflorum

Life Sciences

Volumn 89, Issue 11-12, 2011, Pages 388-394

  Lee, Haeyong ^a   Bae, Sungmin ^a   Kim, Yeong Shik ^b   Yoon, Yoosik ^a  

^a Chung Ang University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

3T3 L1; Adipogenesis; Adipogenic molecular biomarkers; siRNA; Therapeutic compounds

Indexed keywords

AXIN; BETA ACTIN; BETA CATENIN; CCAAT ENHANCER BINDING PROTEIN ALPHA; CYCLIN D1; FATTY ACID BINDING PROTEIN 4; LIPID; MESSENGER RNA; NATURAL PRODUCT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLATYCODIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WNT PROTEIN;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL DIFFERENTIATION; CELL NUCLEUS; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; NONHUMAN; PLATYCODON; PLATYCODON GRANDIFLORUM; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ADIPOSE TISSUE; ANIMALS; BETA CATENIN; CELL CULTURE TECHNIQUES; MICE; PHYTOTHERAPY; PLANT ROOTS; PLATYCODON; RNA; RNA, SMALL INTERFERING; SAPONINS; TRANSFECTION; TRITERPENES; UP-REGULATION; WNT PROTEINS;

PLATYCODON GRANDIFLORUM;

EID: 80052029040     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2011.07.006     Document Type: Article

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