Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-κB activation in RAW 264.7 cells

Life Sciences

Volumn 76, Issue 20, 2005, Pages 2315-2328

  Ahn, Kwang Seok ^a   Noh, Eun Jung ^a   Zhao, Hai Lin ^a   Jung, Sang Hoon ^b   Kang, Sam Sik ^a   Kim, Yeong Shik ^a  

^a Seoul National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Cyclooxygenase; NF B; Nitric oxide; Platycodin saponins; Prostaglandin E2

Indexed keywords

2'' O ACETYLPOLYGALACIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PLATYCODIN; PLATYCODIN A; POLYGALACIN D; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING KINETICS; CONCENTRATION RESPONSE; CYTOTOXICITY; DRUG MECHANISM; ENZYME INHIBITION; GEL MOBILITY SHIFT ASSAY; INHIBITION KINETICS; LETHALITY; MACROPHAGE; MOUSE; NONHUMAN; PLATYCODON; PLATYCODON GRANDIFLORUM;

EID: 14644424029     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2004.10.042     Document Type: Article

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