-
2
-
-
33644838915
-
Soluble MHC-peptide complexes containing long rigid linkers abolish CTL-mediated cytotoxicity
-
Angelov G.S., et al. (2006) Soluble MHC-peptide complexes containing long rigid linkers abolish CTL-mediated cytotoxicity. J Immunol 176:3356-3365. (Pubitemid 43363982)
-
(2006)
Journal of Immunology
, vol.176
, Issue.6
, pp. 3356-3365
-
-
Angelov, G.S.1
Guillaume, P.2
Cebecauer, M.3
Bosshard, G.4
Dojcinovic, D.5
Baumgaertner, P.6
Luescher, I.F.7
-
4
-
-
0027301982
-
A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations
-
Dal Porto J., et al. (1993) A soluble divalent class I major histocompatibility complex molecule inhibits alloreactive T cells at nanomolar concentrations. Proc Natl Acad Sci USA 90:6671-6675.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6671-6675
-
-
Dal Porto, J.1
-
5
-
-
0035451465
-
Antigen-specific blockade of T cells in vivo using dimeric MHC peptide
-
O'Herrin S.M., et al. (2001) Antigen-specific blockade of T cells in vivo using dimeric MHC peptide. J Immunol 167:2555-2560. (Pubitemid 32768882)
-
(2001)
Journal of Immunology
, vol.167
, Issue.5
, pp. 2555-2560
-
-
O'Herrin, S.M.1
Slansky, J.E.2
Tang, Q.3
Markiewicz, M.A.4
Gajewski, T.F.5
Pardoll, D.M.6
Schneck, J.P.7
Bluestone, J.A.8
-
6
-
-
0029163387
-
CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL
-
Boise L.H., et al. (1995) CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL. Immunity 3:87-98.
-
(1995)
Immunity
, vol.3
, pp. 87-98
-
-
Boise, L.H.1
-
7
-
-
0027284230
-
Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation
-
Gimmi C.D., Freeman G.J., Gribben J.G., Gray G., Nadler L.M. (1993) Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc Natl Acad Sci USA 90:6586-6590. (Pubitemid 23207258)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.14
, pp. 6586-6590
-
-
Gimmi, C.D.1
Freeman, G.J.2
Gribben, J.G.3
Gray, G.4
Nadler, L.M.5
-
8
-
-
0026537347
-
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
-
Harding F.A., McArthur J.G., Gross J.A., Raulet D.H., Allison J.P. (1992) CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356:607-609.
-
(1992)
Nature
, vol.356
, pp. 607-609
-
-
Harding, F.A.1
McArthur, J.G.2
Gross, J.A.3
Raulet, D.H.4
Allison, J.P.5
-
9
-
-
0029939945
-
The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance
-
Van Parijs L., Ibraghimov A., Abbas A.K. (1996) The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 4:321-328.
-
(1996)
Immunity
, vol.4
, pp. 321-328
-
-
Van Parijs, L.1
Ibraghimov, A.2
Abbas, A.K.3
-
10
-
-
0034141694
-
+ T cells do not require costimulation for proliferation and differentiation into cytotoxic effector cells
-
+ T cells do not require costimulation for proliferation and differentiation into cytotoxic effector cells. J Immunol 164:1216-1222.
-
(2000)
J Immunol
, vol.164
, pp. 1216-1222
-
-
Wang, B.1
Maile, R.2
Greenwood, R.3
Collins, E.J.4
Frelinger, J.A.5
-
11
-
-
0037108981
-
+ T cells through transfer of the peptide to T cell MHC molecules
-
+ T cells through transfer of the peptide to T cell MHC molecules. Proc Natl Acad Sci USA 99:13729-13734.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13729-13734
-
-
Ge, Q.1
-
12
-
-
0037108790
-
b molecules
-
DOI 10.1073/pnas.212515399
-
Schott E., Bertho N., Ge Q., Maurice M.M., Ploegh H.L. (2002) Class I negative CD8 T cells reveal the confounding role of peptide-transfer onto CD8 T cells stimulated with soluble H2-Kb molecules. Proc Natl Acad Sci USA 99:13735-13740. (Pubitemid 35215450)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.21
, pp. 13735-13740
-
-
Schott, E.1
Bertho, N.2
Ge, Q.3
Maurice, M.M.4
Ploegh, H.L.5
-
13
-
-
34547936659
-
Structural Engineering of pMHC Reagents for T Cell Vaccines and Diagnostics
-
DOI 10.1016/j.chembiol.2007.07.010, PII S1074552107002499
-
Mitaksov V., et al. (2007) Structural engineering of pMHC reagents for T cell vaccines and diagnostics. Chem Biol 14:909-922. (Pubitemid 47268780)
-
(2007)
Chemistry and Biology
, vol.14
, Issue.8
, pp. 909-922
-
-
Mitaksov, V.1
Truscott, S.M.2
Lybarger, L.3
Connolly, J.M.4
Hansen, T.H.5
Fremont, D.H.6
-
14
-
-
0036533556
-
Cutting edge: Single-chain trimers of MHC class I molecules form stable structures that potently stimulate antigen-specific T cells and B cells
-
Yu Y.Y., Netuschil N., Lybarger L., Connolly J.M., Hansen T.H. (2002) Cutting edge: Singlechain trimers of MHC class I molecules form stable structures that potently stimulate antigen-specific T cells and B cells. J Immunol 168:3145-3149. (Pubitemid 34250372)
-
(2002)
Journal of Immunology
, vol.168
, Issue.7
, pp. 3145-3149
-
-
Yu, Y.Y.L.1
Netuschil, N.2
Lybarger, L.3
Connolly, J.M.4
Hansen, T.H.5
-
17
-
-
0037478632
-
+ T cells in autoimmune diabetes
-
DOI 10.1073/pnas.0932778100
-
Lieberman S.M., et al. (2003) Identification of the β cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes. Proc Natl Acad Sci USA 100:8384-8388. (Pubitemid 36842554)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8384-8388
-
-
Lieberman, S.M.1
Evans, A.M.2
Han, B.3
Takaki, T.4
Vinnitskaya, Y.5
Caldwell, J.A.6
Serreze, D.V.7
Shabanowitz, J.8
Hunt, D.F.9
Nathenson, S.G.10
Santamaria, P.11
DiLorenzo, T.P.12
-
18
-
-
0030724897
-
Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice
-
DOI 10.1084/jem.186.10.1663
-
Verdaguer J., et al. (1997) Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice. J Exp Med 186:1663-1676. (Pubitemid 27506280)
-
(1997)
Journal of Experimental Medicine
, vol.186
, Issue.10
, pp. 1663-1676
-
-
Verdaguer, J.1
Schmidt, D.2
Amrani, A.3
Anderson, B.4
Averill, N.5
Santamaria, P.6
-
19
-
-
9144271119
-
Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase
-
+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase. J Immunol 173:6727-6734.
-
(2004)
J Immunol
, vol.173
, pp. 6727-6734
-
-
Lieberman, S.M.1
-
20
-
-
0037237655
-
Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood
-
DOI 10.1172/JCI200316409
-
Trudeau J.D., et al. (2003) Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood. J Clin Invest 111:217-223. (Pubitemid 36105920)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.2
, pp. 217-223
-
-
Trudeau, J.D.1
Kelly-Smith, C.2
Verchere, C.B.3
Elliott, J.F.4
Dutz, J.P.5
Finegood, D.T.6
Santamaria, P.7
Tan, R.8
-
21
-
-
45249117656
-
Identification of novel IGRP epitopes targeted in type 1 diabetes patients
-
Jarchum I., Nichol L., Trucco M., Santamaria P., DiLorenzo T.P. (2008) Identification of novel IGRP epitopes targeted in type 1 diabetes patients. Clin Immunol 127:359-365.
-
(2008)
Clin Immunol
, vol.127
, pp. 359-365
-
-
Jarchum, I.1
Nichol, L.2
Trucco, M.3
Santamaria, P.4
DiLorenzo, T.P.5
-
22
-
-
33847338541
-
+ T-cell responses identify β-cell autoimmunity in human type 1 diabetes
-
+ T-cell responses identify β-cell autoimmunity in human type 1 diabetes. Diabetes 56:613-621.
-
(2007)
Diabetes
, vol.56
, pp. 613-621
-
-
Mallone, R.1
-
23
-
-
33845533220
-
Identification of novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives
-
DOI 10.2337/db06-0066
-
Standifer N.E., et al. (2006) Identification of Novel HLA-A*0201-restricted epitopes in recent-onset type 1 diabetic subjects and antibody-positive relatives. Diabetes 55: 3061-3067. (Pubitemid 44923643)
-
(2006)
Diabetes
, vol.55
, Issue.11
, pp. 3061-3067
-
-
Standifer, N.E.1
Ouyang, Q.2
Panagiotopoulos, C.3
Verchere, C.B.4
Tan, R.5
Greenbaum, C.J.6
Pihoker, C.7
Nepom, G.T.8
-
24
-
-
0026715263
-
Identification and quantification of a naturally presented peptide as recognized by cytotoxic T lymphocytes specific for an immunogenic tumor variant
-
Wallny H.J., et al. (1992) Identification and quantification of a naturally presented peptide as recognized by cytotoxic T lymphocytes specific for an immunogenic tumor variant. Int Immunol 4:1085-1090.
-
(1992)
Int Immunol
, vol.4
, pp. 1085-1090
-
-
Wallny, H.J.1
-
26
-
-
0027587199
-
Structural analysis of MHC class I molecules with bound peptide antigens
-
Wilson I.A., Fremont D.H. (1993) Structural analysis of MHC class I molecules with bound peptide antigens. Semin Immunol 5:75-80.
-
(1993)
Semin Immunol
, vol.5
, pp. 75-80
-
-
Wilson, I.A.1
Fremont, D.H.2
-
28
-
-
0035879220
-
Expansion of the antigenic repertoire of a single T cell receptor upon T cell activation
-
Amrani A., et al. (2001) Expansion of the antigenic repertoire of a single T cell receptor upon T cell activation. J Immunol 167:655-666. (Pubitemid 32660817)
-
(2001)
Journal of Immunology
, vol.167
, Issue.2
, pp. 655-666
-
-
Amrani, A.1
Serra, P.2
Yamanouchi, J.3
Trudeau, J.D.4
Tan, R.5
Elliott, J.F.6
Santamaria, P.7
-
29
-
-
0038136973
-
Soluble major histocompatibility complex-peptide octamers with impaired CD8 binding selectively induce Fas-dependent apoptosis
-
DOI 10.1074/jbc.M208863200
-
Guillaume P., et al. (2003) Soluble major histocompatibility complex-peptide octamers with impaired CD8 binding selectively induce Fas-dependent apoptosis. J Biol Chem 278:4500-4509. (Pubitemid 36800945)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.7
, pp. 4500-4509
-
-
Guillaume, P.1
Legler, D.F.2
Boucheron, N.3
Doucey, M.-A.4
Cerottini, J.-C.5
Luescher, I.F.6
-
30
-
-
44449148889
-
Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice
-
Krishnamurthy B., et al. (2008) Autoimmunity to both proinsulin and IGRP is required for diabetes in nonobese diabetic 8.3 TCR transgenic mice. J Immunol 180:4458-4464.
-
(2008)
J Immunol
, vol.180
, pp. 4458-4464
-
-
Krishnamurthy, B.1
-
31
-
-
0036467353
-
In situ beta cell death promotes priming of diabetogenic CD8 T lymphocytes
-
Zhang Y., et al. (2002) In situ β cell death promotes priming of diabetogenic CD8 T lymphocytes. J Immunol 168:1466-1472. (Pubitemid 34094520)
-
(2002)
Journal of Immunology
, vol.168
, Issue.3
, pp. 1466-1472
-
-
Zhang, Y.1
O'Brien, B.2
Trudeau, J.3
Tan, R.4
Santamaria, P.5
Dutz, J.P.6
-
32
-
-
65349088492
-
Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy
-
Podojil J.R., Miller S.D. (2009) Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy. Immunol Rev 229:337-355.
-
(2009)
Immunol Rev
, vol.229
, pp. 337-355
-
-
Podojil, J.R.1
Miller, S.D.2
-
33
-
-
79952026221
-
Abatacept treatment for rheumatoid arthritis
-
Schiff M. (2011) Abatacept treatment for rheumatoid arthritis. Rheumatology (Oxford) 50:437-449.
-
(2011)
Rheumatology (Oxford)
, vol.50
, pp. 437-449
-
-
Schiff, M.1
-
34
-
-
77957257899
-
Basic and translational applications of engineered MHC class I proteins
-
Hansen T.H., Connolly J.M., Gould K.G., Fremont D.H. (2010) Basic and translational applications of engineered MHC class I proteins. Trends Immunol 31:363-369.
-
(2010)
Trends Immunol
, vol.31
, pp. 363-369
-
-
Hansen, T.H.1
Connolly, J.M.2
Gould, K.G.3
Fremont, D.H.4
-
35
-
-
0028293862
-
Failure to demonstrate long-lived MHC saturation both in vitro and in vivo: Implications for therapeutic potential of MHC-blocking peptides
-
Ishioka G.Y., et al. (1994) Failure to demonstrate long-lived MHC saturation both in vitro and in vivo. Implications for therapeutic potential of MHC-blocking peptides. J Immunol 152:4310-4319. (Pubitemid 24134388)
-
(1994)
Journal of Immunology
, vol.152
, Issue.9
, pp. 4310-4319
-
-
Ishioka, G.Y.1
Adorini, L.2
Guery, J.-C.3
Gaeta, F.C.A.4
LaFond, R.5
Alexander, J.6
Powell, M.F.7
Sette, A.8
Grey, H.M.9
-
36
-
-
0036790542
-
Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B: 9-23 and B: 9-23 and B13-23
-
Liu E., et al. (2002) Anti-peptide autoantibodies and fatal anaphylaxis in NOD mice in response to insulin self-peptides B: 9-23 and B: 9-23 and B13-23. J Clin Invest 110:1021-1027.
-
(2002)
J Clin Invest
, vol.110
, pp. 1021-1027
-
-
Liu, E.1
-
37
-
-
33751552197
-
Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway
-
DOI 10.1084/jem.20061577
-
Fife B.T., et al. (2006) Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway. J Exp Med 203:2737-2747. (Pubitemid 44833349)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.12
, pp. 2737-2747
-
-
Fife, B.T.1
Guleria, I.2
Bupp, M.G.3
Eagar, T.N.4
Tang, Q.5
Bour-Jordan, H.6
Yagita, H.7
Azuma, M.8
Sayegh, M.H.9
Bluestone, J.A.10
-
38
-
-
79953172219
-
Prevention of "humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach
-
Niens M., et al. (2011) Prevention of "humanized" diabetogenic CD8 T-cell responses in HLA-transgenic NOD mice by a multipeptide coupled-cell approach. Diabetes 60: 1229-1236.
-
(2011)
Diabetes
, vol.60
, pp. 1229-1236
-
-
Niens, M.1
-
39
-
-
0035017468
-
A novel approach to antigen-specific deletion of CTL with minimal cellular activation using α3 domain mutants of MHC class I/peptide complex
-
Xu X.N., et al. (2001) A novel approach to antigen-specific deletion of CTL with minimal cellular activation using α3 domain mutants of MHC class I/peptide complex. Immunity 14:591-602.
-
(2001)
Immunity
, vol.14
, pp. 591-602
-
-
Xu, X.N.1
-
40
-
-
0035871624
-
Anergy induction by dimeric TCR ligands
-
Appel H., Seth N.P., Gauthier L., Wucherpfennig K.W.(2001) Anergy induction by dimeric TCR ligands. J Immunol 166:5279-5285. (Pubitemid 32280746)
-
(2001)
Journal of Immunology
, vol.166
, Issue.8
, pp. 5279-5285
-
-
Appel, H.1
Seth, N.P.2
Gauthier, L.3
Wucherpfennig, K.W.4
-
41
-
-
0036226602
-
+ T cells by a soluble dimeric peptide-MHC class II chimera
-
+ T cells by a soluble dimeric peptide-MHC class II chimera. Nat Immunol 3:383-391.
-
(2002)
Nat Immunol
, vol.3
, pp. 383-391
-
-
Casares, S.1
-
42
-
-
0242494202
-
Peptide-MHC Class II Dimers as Therapeutics to Modulate Antigen-Specific T Cell Responses in Autoimmune Diabetes
-
Masteller E.L., et al. (2003) Peptide-MHC class II dimers as therapeutics to modulate antigen-specific T cell responses in autoimmune diabetes. J Immunol 171:5587-5595. (Pubitemid 37432850)
-
(2003)
Journal of Immunology
, vol.171
, Issue.10
, pp. 5587-5595
-
-
Masteller, E.L.1
Warner, M.R.2
Ferlin, W.3
Judkowski, V.4
Wilson, D.5
Glaichenhaus, N.6
Bluestone, J.A.7
-
43
-
-
0036499141
-
A single-chain class II MHC-IgG3 fusion protein inhibits autoimmune arthritis by induction of antigen-specific hyporesponsiveness
-
Zuo L., et al. (2002) A single-chain class II MHC-IgG3 fusion protein inhibits autoimmune arthritis by induction of antigen-specific hyporesponsiveness. J Immunol 168:2554-2559. (Pubitemid 34171864)
-
(2002)
Journal of Immunology
, vol.168
, Issue.5
, pp. 2554-2559
-
-
Zuo, L.1
Cullen, C.M.2
DeLay, M.L.3
Thornton, S.4
Myers, L.K.5
Rosloniec, E.F.6
Boivin, G.P.7
Hirsch, R.8
-
44
-
-
70449711382
-
Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination
-
Li L., Yi Z., Wang B., Tisch R. (2009) Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination. J Immunol 183:4809-4816.
-
(2009)
J Immunol
, vol.183
, pp. 4809-4816
-
-
Li, L.1
Yi, Z.2
Wang, B.3
Tisch, R.4
-
45
-
-
77951882989
-
Reversal of autoimmunity by boosting memory-like autoregulatory T cells
-
Tsai S., et al. (2010) Reversal of autoimmunity by boosting memory-like autoregulatory T cells. Immunity 32:568-580.
-
(2010)
Immunity
, vol.32
, pp. 568-580
-
-
Tsai, S.1
-
46
-
-
78049423506
-
An update on the use of NOD mice to study autoimmune (Type 1) diabetes
-
Chaparro R.J., DiLorenzo T.P. (2010) An update on the use of NOD mice to study autoimmune (Type 1) diabetes. Expert Rev Clin Immunol 6:939-955.
-
(2010)
Expert Rev Clin Immunol
, vol.6
, pp. 939-955
-
-
Chaparro, R.J.1
DiLorenzo, T.P.2
-
47
-
-
0034176744
-
Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions
-
Graser R.T., et al. (2000) Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions. J Immunol 164:3913-3918. (Pubitemid 30169851)
-
(2000)
Journal of Immunology
, vol.164
, Issue.7
, pp. 3913-3918
-
-
Graser, R.T.1
DiLorenzo, T.P.2
Wang, F.3
Christianson, G.J.4
Chapman, H.D.5
Roopenian, D.C.6
Nathenson, S.G.7
Serreze, D.V.8
-
48
-
-
53049086810
-
+ T cells from the islets of NOD mice and their use for the study of autoreactive specificities
-
+ T cells from the islets of NOD mice and their use for the study of autoreactive specificities. J Immunol Methods 339:66-73.
-
(2008)
J Immunol Methods
, vol.339
, pp. 66-73
-
-
Jarchum, I.1
Takaki, T.2
DiLorenzo, T.P.3
|