A novel approach to antigen-specific deletion of CTL with minimal cellular activation using α3 domain mutants of MHC class I/peptide complex

Immunity

Volumn 14, Issue 5, 2001, Pages 591-602

  Xu, Xiao Ning ^a   Purbhoo, Marco A ^b   Chen, Nan ^a   Mongkolsapaya, Juthathip ^a   Cox, Jennifer H ^a   Meier, Ute Christiane ^a   Tafuro, Sabrina ^a   Rod Dunbar, P Rod ^a   Sewell, Andy K ^b   Hourigan, Christopher S ^a   Appay, Victor ^a   Cerundolo, Vincenzo ^a   Burrows, Scott R ^c   McMichael, Andrew J ^a   Screaton, Gavin R ^a  

^a MRC Human Immunology Unit   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; FAS LIGAND; GAG PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; T LYMPHOCYTE RECEPTOR;

ALPHA3 DOMAIN MUTANT; ANTIGEN SPECIFICITY; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL CONTACT; CELL DEATH; CELL LINE; CHROMOSOME DELETION; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; MEDIATOR; MUTANT; PRIORITY JOURNAL; PROTEIN BINDING; RECEPTOR BINDING; TARGET CELL;

EID: 0035017468     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(01)00133-9     Document Type: Article

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