-
1
-
-
0024521844
-
Signal transduction by the platelet-derived growth factor receptor
-
Williams, L. T. (1989) Signal transduction by the platelet-derived growth factor receptor. Science 243, 1564-1570
-
(1989)
Science
, vol.243
, pp. 1564-1570
-
-
Williams, L.T.1
-
2
-
-
0028589148
-
Platelet-derived growth factor receptor signals
-
Claesson-Welsh, L. (1994) Platelet-derived growth factor receptor signals. J. Biol. Chem. 269, 32023-32026
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32023-32026
-
-
Claesson-Welsh, L.1
-
3
-
-
0026664293
-
GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the PDGF receptor β subunit
-
Kazlauskas, A., Kashishian, A., Cooper, J., and Valius, M. (1992) GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the PDGF receptor β subunit. Mol. Cell. Biol. 12, 2534-2544
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 2534-2544
-
-
Kazlauskas, A.1
Kashishian, A.2
Cooper, J.3
Valius, M.4
-
4
-
-
0027211693
-
Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
-
Valius, M., and Kazlauskas, A. (1993) Phospholipase C-γ1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal. Cell 73, 321-324
-
(1993)
Cell
, vol.73
, pp. 321-324
-
-
Valius, M.1
Kazlauskas, A.2
-
5
-
-
0027371722
-
Sphingosine-1-phosphate as a second messenger in cell proliferation induced by PDGF and FCS mitogens
-
Olivera, A., and Spiegel, S. (1993) Sphingosine-1-phosphate as a second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature (London) 365, 557-560
-
(1993)
Nature (London)
, vol.365
, pp. 557-560
-
-
Olivera, A.1
Spiegel, S.2
-
6
-
-
0027991078
-
Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway
-
Mattie, M., Brooker, G., and Spiegel, S. (1994) Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway. J. Biol. Chem. 269, 3181-3188
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 3181-3188
-
-
Mattie, M.1
Brooker, G.2
Spiegel, S.3
-
7
-
-
0026457994
-
Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation
-
Desai, N. N., Zhang, H., Olivera, A., Seki, T., Brooker, G., and Spiegel, S. (1992) Sphingosine-1-phosphate, a metabolite of sphingosine, increases phosphatidic acid levels by phospholipase D activation. J. Biol. Chem. 267, 23122-23128
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 23122-23128
-
-
Desai, N.N.1
Zhang, H.2
Olivera, A.3
Seki, T.4
Brooker, G.5
Spiegel, S.6
-
8
-
-
0029079324
-
Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism
-
Wu, J., Spiegel, S., and Sturgill, T. W. (1995) Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism. J. Biol. Chem. 270, 11484-11488
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 11484-11488
-
-
Wu, J.1
Spiegel, S.2
Sturgill, T.W.3
-
9
-
-
0029948396
-
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
-
Cuvillier, O., Pirianov, G., Kleuser, B., Vanek, P. G., Coso, O. A., Gutkind, S., and Spiegel, S. (1996) Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate. Nature (London) 381, 800-803
-
(1996)
Nature (London)
, vol.381
, pp. 800-803
-
-
Cuvillier, O.1
Pirianov, G.2
Kleuser, B.3
Vanek, P.G.4
Coso, O.A.5
Gutkind, S.6
Spiegel, S.7
-
10
-
-
0028322142
-
Sphingosine 1-phosphate, a novel signaling molecule, stimulates DNA binding activity of AP-1 in quiescent Swiss 3T3 fibroblasts
-
Su, Y., Rosenthal, D., Smulson, M., and Spiegel, S. (1994) Sphingosine 1-phosphate, a novel signaling molecule, stimulates DNA binding activity of AP-1 in quiescent Swiss 3T3 fibroblasts. J. Biol. Chem. 269, 16512-16517
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 16512-16517
-
-
Su, Y.1
Rosenthal, D.2
Smulson, M.3
Spiegel, S.4
-
11
-
-
0028300922
-
Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): Demonstration of cell type-specific response
-
Mazurek, N., Megidish, T., Hakomori, S.-I., and Igarashi, Y. (1994) Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): demonstration of cell type-specific response. Biochem. Biophys. Res. Commun. 198, 1-9
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.198
, pp. 1-9
-
-
Mazurek, N.1
Megidish, T.2
Hakomori, S.-I.3
Igarashi, Y.4
-
12
-
-
0030592536
-
Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity
-
Buehrer, B. M., Bardes, E. S., and Bell, R. M. (1996) Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity. Biochim. Biophys. Acta 1303, 233-242
-
(1996)
Biochim. Biophys. Acta
, vol.1303
, pp. 233-242
-
-
Buehrer, B.M.1
Bardes, E.S.2
Bell, R.M.3
-
13
-
-
0029775306
-
Involvement of sphingolipids metabolites in cellular proliferation modulated by ganglioside GM1
-
Wang, F., Buckley, N. E., Olivera, A., Goodemote, K. A., Su, Y., and Spiegel, S. (1996) Involvement of sphingolipids metabolites in cellular proliferation modulated by ganglioside GM1. Glycoconjugate J. 13, 937-45
-
(1996)
Glycoconjugate J.
, vol.13
, pp. 937-945
-
-
Wang, F.1
Buckley, N.E.2
Olivera, A.3
Goodemote, K.A.4
Su, Y.5
Spiegel, S.6
-
14
-
-
0030780015
-
Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation
-
Edsall, L. C., Pirianov, G. G., and Spiegel, S. (1997) Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation. J. Neurosci 17, 6952-6960
-
(1997)
J. Neurosci
, vol.17
, pp. 6952-6960
-
-
Edsall, L.C.1
Pirianov, G.G.2
Spiegel, S.3
-
15
-
-
0030728721
-
Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors
-
Rius, R. A., Edsall, L. C., and Spiegel, S. (1997) Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors. FEBS Lett. 417, 173-176
-
(1997)
FEBS Lett.
, vol.417
, pp. 173-176
-
-
Rius, R.A.1
Edsall, L.C.2
Spiegel, S.3
-
16
-
-
0032056362
-
3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase
-
3 inhibits programmed cell death in HL-60 cells by activation of sphingosine kinase. Cancer Res. 58, 1817-1824
-
(1998)
Cancer Res.
, vol.58
, pp. 1817-1824
-
-
Kleuser, B.1
Cuvillier, O.2
Spiegel, S.3
-
17
-
-
0029996127
-
Calcium mobilization via sphingosine kinase in signalling by the FcεRI antigen receptor
-
Choi, O., H., Kim, J.-H., and Kinet, J.-P. (1996) Calcium mobilization via sphingosine kinase in signalling by the FcεRI antigen receptor. Nature (London) 380, 634-636
-
(1996)
Nature (London)
, vol.380
, pp. 634-636
-
-
Choi, O.H.1
Kim, J.-H.2
Kinet, J.-P.3
-
18
-
-
0032540010
-
FcγRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking
-
Melendez, A., Floto, R. A., Gillooly, D. J., Harnett, M. M., and Allen, J. M. (1998) FcγRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking. J. Biol. Chem. 273, 9393-9402
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 9393-9402
-
-
Melendez, A.1
Floto, R.A.2
Gillooly, D.J.3
Harnett, M.M.4
Allen, J.M.5
-
19
-
-
2642630721
-
2+ signalling by G-protein-coupled receptors
-
2+ signalling by G-protein-coupled receptors. EMBO J. 17, 2830-2837
-
(1998)
EMBO J.
, vol.17
, pp. 2830-2837
-
-
Meyer Zu Heringdorf, D.1
Lass, H.2
Alemany, R.3
Laser, K.T.4
Neumann, E.5
Zhang, C.6
Schmidt, M.7
Rauen, U.8
Jakobs, K.H.9
Van Koppen, C.J.10
-
20
-
-
0032530864
-
N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: Modulation of cellular levels of sphingosine-1-phosphate and ceramide
-
Edsall, L. C., Van Brocklyn, J. R., Cuvillier, O., Kleuser, B., and Spiegel, S. (1998) N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: Modulation of cellular levels of sphingosine-1-phosphate and ceramide. Biochemistry 37, 12892-12898
-
(1998)
Biochemistry
, vol.37
, pp. 12892-12898
-
-
Edsall, L.C.1
Van Brocklyn, J.R.2
Cuvillier, O.3
Kleuser, B.4
Spiegel, S.5
-
21
-
-
0030891014
-
Divergence in signal transduction pathways of PDGF and EGF receptors: Involvement of sphingosine-1-phosphate in PDGF but not EGF signaling
-
Rani, C. S., Berger, A., Wu, J., Sturgill, T. W., Beitner-Johnson, D., LeRoith, D., Varticovski, L., and Spiegel, S. (1997) Divergence in signal transduction pathways of PDGF and EGF receptors: involvement of sphingosine-1-phosphate in PDGF but not EGF signaling. J. Biol. Chem. 272, 10777-10783
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 10777-10783
-
-
Rani, C.S.1
Berger, A.2
Wu, J.3
Sturgill, T.W.4
Beitner-Johnson, D.5
Leroith, D.6
Varticovski, L.7
Spiegel, S.8
-
22
-
-
0027506762
-
Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively
-
Valius, M., Bazenet, C., and Kazlauskas, A. (1993) Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively. Mol. Cell. Biol. 13, 133-143
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 133-143
-
-
Valius, M.1
Bazenet, C.2
Kazlauskas, A.3
-
23
-
-
0030938093
-
Platelet-derived growth factor-dependent cellular transformation requires either phospholipase C γ or phosphatidylinositol 3 kinase
-
DeMali, K. A., Whiteford, C. C., Ulug, E. T., and Kazlauskas, A. (1997) Platelet-derived growth factor-dependent cellular transformation requires either phospholipase C γ or phosphatidylinositol 3 kinase. J. Biol. Chem. 272, 9011-9018
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9011-9018
-
-
DeMali, K.A.1
Whiteford, C.C.2
Ulug, E.T.3
Kazlauskas, A.4
-
24
-
-
0031450917
-
The platelet-derived growth factor β receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputs
-
Montmayeur, J. P., Valius, M., Vandenheede, J., and Kazlauskas, A. (1997) The platelet-derived growth factor β receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputs. J. Biol. Chem. 272, 32670-32678
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32670-32678
-
-
Montmayeur, J.P.1
Valius, M.2
Vandenheede, J.3
Kazlauskas, A.4
-
25
-
-
0031899815
-
Activation of Src family members is not required for the platelet-derived growth factor β receptor to initiate mitogenesis
-
DeMali, K. A., and Kazlauskas, A. (1998) Activation of Src family members is not required for the platelet-derived growth factor β receptor to initiate mitogenesis. Mol Cell. Biol. 18, 2014-2022
-
(1998)
Mol Cell. Biol.
, vol.18
, pp. 2014-2022
-
-
DeMali, K.A.1
Kazlauskas, A.2
-
26
-
-
0032502626
-
U73122 and U73343 inhibit receptor-mediated phospholipase D activation downstream of phospholipase C in CHO cells
-
Bosch, R. R., Patel, A. M., Van Emst-de Vries, S. E., Smeets, R. L., De Pont, J. J., and Willems, P. H. (1998) U73122 and U73343 inhibit receptor-mediated phospholipase D activation downstream of phospholipase C in CHO cells. Eur. J. Pharmacol. 346, 345-351
-
(1998)
Eur. J. Pharmacol.
, vol.346
, pp. 345-351
-
-
Bosch, R.R.1
Patel, A.M.2
Van Emst-De Vries, S.E.3
Smeets, R.L.4
De Pont, J.J.5
Willems, P.H.6
-
27
-
-
0031770306
-
Evidence for separate effects of U73122 on phospholipase C and calcium channels in human platelets
-
Pulcinelli, F. M., Gresele, P., Bonuglia, M., and Gazzaniga, P. P. (1998) Evidence for separate effects of U73122 on phospholipase C and calcium channels in human platelets. Biochem. Pharmacol. 56, 1481-1484
-
(1998)
Biochem. Pharmacol.
, vol.56
, pp. 1481-1484
-
-
Pulcinelli, F.M.1
Gresele, P.2
Bonuglia, M.3
Gazzaniga, P.P.4
-
29
-
-
0029060391
-
Protein kinase C and lipid signaling for sustained cellular responses
-
Nishizuka, Y. (1995) Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 9, 484-496
-
(1995)
FASEB J.
, vol.9
, pp. 484-496
-
-
Nishizuka, Y.1
-
30
-
-
0028171403
-
Activation of phospholipase C-γ is necessary for stimulation of phospholipase D by platelet-derived growth factor
-
Yeo, E. J., Kazlauskas, A., and Exton, J. H. (1994) Activation of phospholipase C-γ is necessary for stimulation of phospholipase D by platelet-derived growth factor. J. Biol. Chem. 269, 27823-27826
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 27823-27826
-
-
Yeo, E.J.1
Kazlauskas, A.2
Exton, J.H.3
-
31
-
-
0030663481
-
Non-capacitative calcium entry in Chinese hamster ovary cells expressing the platelet-derived growth factor receptor
-
Mathias, R. S., Zhang, S. J., Wilson, E., Gardner, P., and Ives, H. E. (1997) Non-capacitative calcium entry in Chinese hamster ovary cells expressing the platelet-derived growth factor receptor. J. Biol. Chem. 272, 29076-29082
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29076-29082
-
-
Mathias, R.S.1
Zhang, S.J.2
Wilson, E.3
Gardner, P.4
Ives, H.E.5
-
32
-
-
0032566780
-
Calcium release-activated calcium current (ICRAC) is a direct target for sphingosine
-
Mathes, C., Fleig, A., and Penner, R. (1998) Calcium release-activated calcium current (ICRAC) Is a direct target for sphingosine. J. Biol. Chem. 273, 25020-25030
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25020-25030
-
-
Mathes, C.1
Fleig, A.2
Penner, R.3
-
33
-
-
0032508706
-
Molecular cloning and functional characterization of murine sphingosine kinase
-
Kohama, T., Olivera, A., Edsall, L., Nagiec, M. M., Dickson, R., and Spiegel, S. (1998) Molecular cloning and functional characterization of murine sphingosine kinase. J. Biol. Chem. 273, 23722-23728
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 23722-23728
-
-
Kohama, T.1
Olivera, A.2
Edsall, L.3
Nagiec, M.M.4
Dickson, R.5
Spiegel, S.6
|