Schizophrenia is associated with dysregulation of a Cdk5 activator that regulates synaptic protein expression and cognition

Brain

Volumn 134, Issue 8, 2011, Pages 2408-2421

  Engmann, Olivia ^a   Hortobágyi, Tibor ^a   Pidsley, Ruth ^a   Troakes, Claire ^a   Bernstein, Hans Gert ^b   Kreutz, Michael R ^c   Mill, Jonathan ^a   Nikolic, Margareta ^d   Giese, Karl Peter ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

^d IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

animal models; brain; cognition; schizophrenia; signalling

Indexed keywords

CYCLIN DEPENDENT KINASE 5; HISTONE DEACETYLASE 1;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITION; CONTROLLED STUDY; FEMALE; HETEROZYGOSITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHIZOPHRENIA; SYNAPSE;

ACOUSTIC STIMULATION; ANALYSIS OF VARIANCE; ANIMALS; BENZAMIDES; BRAIN; CELL CYCLE PROTEINS; COGNITION DISORDERS; ENDOPHENOTYPES; EXPLORATORY BEHAVIOR; FEMALE; GENE EXPRESSION REGULATION; GTP PHOSPHOHYDROLASES; HISTONE DEACETYLASE INHIBITORS; HUMANS; INHIBITION (PSYCHOLOGY); INTERPERSONAL RELATIONS; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; MUCOPROTEINS; MUTATION; NERVE TISSUE PROTEINS; POSTMORTEM CHANGES; PYRIDINES; REWARD; SCHIZOPHRENIA; SEPTINS; SEX FACTORS; SYNAPSES;

EID: 80051966439     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awr155     Document Type: Article

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