Cyclin-dependent kinase 5 activator p25 Is generated during memory formation and is reduced at an early stage in Alzheimer's disease

Biological Psychiatry

Volumn 70, Issue 2, 2011, Pages 159-168

  Engmann, Olivia ^a   Hortobágyi, Tibor ^a   Thompson, Andrew J ^a   Guadagno, Jennifer ^a   Troakes, Claire ^a   Soriano, Salvador ^a,c   Al Sarraj, Safa ^b   Kim, Yong ^d   Giese, Karl Peter ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING S COLLEGE HOSPITAL   (United Kingdom)

^c LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Cdk5; memory; p25; p35

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE 5; SEPTIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SYNAPTOSOME; CELL CYCLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENZYME SUBUNIT; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MASS SPECTROMETRY; MAZE TEST; MEMORY; MOUSE; NERVE CELL PLASTICITY; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; WESTERN BLOTTING;

ALZHEIMER DISEASE; ANIMALS; BRAIN; CYCLIN D1; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GTP PHOSPHOHYDROLASES; HUMANS; MASS SPECTROMETRY; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; NERVE TISSUE PROTEINS; PHOSPHOPYRUVATE HYDRATASE; SEPTINS; SYNAPSES; SYNAPTOSOMES; TAU PROTEINS;

EID: 79959705293     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.04.011     Document Type: Article

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