Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 47, 2008, Pages 18561-18566

  Meyer, Douglas A ^a   Richer, Edmond ^b   Benkovic, Stanley A ^c   Hayashi, Kanehiro ^a   Kansy, Janice W ^a   Hale, Carly F ^a   Moy, Lily Y ^d,g   Kim, Yong ^e   O'Callaghan, James P ^c   Tsai, Li Huei ^d   Greengard, Paul ^e   Nairn, Angus C ^f   Cowan, Christopher W ^a   Miller, Diane B ^c   Antich, Pietro ^b   Bibb, James A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e ROCKEFELLER UNIVERSITY   (United States)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Addiction; Dopamine; Neurodegeneration; p25; Spines

Indexed keywords

COCAINE; CYCLIN DEPENDENT KINASE 5; DOPAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN P25; PROTEIN P35;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN FUNCTION; CONTROLLED STUDY; CORPUS STRIATUM; DENDRITIC SPINE; DRUG RESPONSE; LEARNING; LOCOMOTION; MOTOR COORDINATION; MOUSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE; CORPUS STRIATUM; CYCLIN-DEPENDENT KINASE 5; DENDRITES; LEARNING; LOCOMOTION; MICE; MICE, TRANSGENIC; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 57049103226     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0806078105     Document Type: Article

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