Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration

Brain

Volumn 133, Issue 6, 2010, Pages 1763-1771

  Nishimura, Agnes L ^a   Upunski, Vera ^b   Troakes, Claire ^a   Kathe, Claudia ^a   Fratta, Pietro ^a   Howell, Michael ^c   Gallo, Jean Marc ^a   Hortobágyi, Tibor ^a   Shaw, Christopher E ^a   Rogelj, Boris ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

^c THE FRANCIS CRICK INSTITUTE   (United Kingdom)

Author keywords

Cellular apoptosis susceptibility; Frontotemporal lobar degeneration; Karyopherin 1; Nuclear transport; TDP 43

Indexed keywords

GLUTATHIONE TRANSFERASE; KARYOPHERIN BETA; SMALL INTERFERING RNA; TAR DNA BINDING PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS; ARTICLE; AUTOPSY; CELL DAMAGE; FRONTOTEMPORAL DEMENTIA; HUMAN; NUCLEAR IMPORT IMPAIRMENT; PATHOGENESIS; PRIORITY JOURNAL;

EID: 77953019135     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awq111     Document Type: Article

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