Influenza-specific T cells from older people are enriched in the late effector subset and their presence inversely correlates with vaccine response

PLoS ONE

Volumn 6, Issue 8, 2011, Pages

  Wagar, Lisa E ^a   Gentleman, Beth ^b   Pircher, Hanspeter ^c   McElhaney, Janet E ^b,d   Watts, Tania H ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF FREIBURG   (Germany)

^d UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD45RA ANTIGEN; CD57 ANTIGEN; GAMMA INTERFERON; HLA A2 ANTIGEN; INFLUENZA VACCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN; NATURAL KILLER CELL LECTIN LIKE RECEPTOR; NATURAL KILLER CELL LECTIN LIKE RECEPTOR G1; UNCLASSIFIED DRUG; T LYMPHOCYTE RECEPTOR;

AGED; AGING; ANTIBODY PRODUCTION; ARTICLE; CD8+ T LYMPHOCYTE; CELL AGING; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG RESPONSE; EFFECTOR CELL; EX VIVO STUDY; HUMAN; HUMAN CELL; IMMUNE SYSTEM; INFLUENZA VACCINATION; INFLUENZA VIRUS A; MEMORY T LYMPHOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; ADULT; AGE; BLOOD; CELL CULTURE; DRUG EFFECT; HUMORAL IMMUNITY; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; INFLUENZA; T LYMPHOCYTE;

ADULT; AGE FACTORS; AGED; BLOOD; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; HUMANS; IMMUNITY, HUMORAL; IMMUNOLOGIC MEMORY; INFLUENZA VACCINES; INFLUENZA, HUMAN; T-CELL ANTIGEN RECEPTOR SPECIFICITY; T-LYMPHOCYTES;

EID: 80051944712     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023698     Document Type: Article

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