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Volumn 13, Issue 7, 2011, Pages 774-785

Dendritic celltumor cell hybrids and immunotherapy: What's next?

Author keywords

Cancer immunotherapy; Cell fusion; Dendritic cells; Fusogenic membrane glycoproteins

Indexed keywords

DENDRITIC CELL VACCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE PROTEIN; TUMOR ANTIGEN; VIRUS GLYCOPROTEIN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2;

EID: 80051850073     PISSN: 14653249     EISSN: 14772566     Source Type: Journal    
DOI: 10.3109/14653249.2011.553593     Document Type: Review
Times cited : (16)

References (148)
  • 1
    • 0032145473 scopus 로고    scopus 로고
    • Bcl-2-mediated inhibition of apoptosis prevents immunogenicity and restores tumorigenicity of spontaneously regressive tumors
    • Bonnotte B, Favre N, Moutet M, Fromentin A, Solary E, Martin M, et al. Bcl-2-mediated inhibition of apoptosis prevents immunogenicity and restores tumorigenicity of spontaneously regressive tumors. J Immunol. 1998;161:1433-8.
    • (1998) J Immunol , vol.161 , pp. 1433-1438
    • Bonnotte, B.1    Favre, N.2    Moutet, M.3    Fromentin, A.4    Solary, E.5    Martin, M.6
  • 2
    • 0034651967 scopus 로고    scopus 로고
    • Role of tumor cell apoptosis in tumor antigen migration to the draining lymph nodes
    • Bonnotte B, Favre N, Moutet M, Fromentin A, Solary E, Martin M, et al. Role of tumor cell apoptosis in tumor antigen migration to the draining lymph nodes. J Immunol. 2000;164:1995-2000.
    • (2000) J Immunol , vol.164 , pp. 1995-2000
    • Bonnotte, B.1    Favre, N.2    Moutet, M.3    Fromentin, A.4    Solary, E.5    Martin, M.6
  • 3
    • 0034292406 scopus 로고    scopus 로고
    • Dendritic cells capture killed tumor cells and present their antigens to elicit tumor-specific immune responses
    • Nouri-Shirazi M, Banchereau J, Bell D, Burkeholder S, Kraus ET, Davoust J, et al. Dendritic cells capture killed tumor cells and present their antigens to elicit tumor-specific immune responses. J Immunol. 2000;165:3797-803.
    • (2000) J Immunol , vol.165 , pp. 3797-3803
    • Nouri-Shirazi, M.1    Banchereau, J.2    Bell, D.3    Burkeholder, S.4    Kraus, E.T.5    Davoust, J.6
  • 4
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature. 1998;392:245-52.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 5
    • 0035500578 scopus 로고    scopus 로고
    • Identifi cation of tumor-infiltrating macrophages as the killers of tumor cells after immunization in a rat model system
    • Bonnotte B, Larmonier N, Favre N, Fromentin A, Moutet M, Martin M, et al. Identifi cation of tumor-infiltrating macrophages as the killers of tumor cells after immunization in a rat model system. J Immunol. 2001;167:5077-83.
    • (2001) J Immunol , vol.167 , pp. 5077-5083
    • Bonnotte, B.1    Larmonier, N.2    Favre, N.3    Fromentin, A.4    Moutet, M.5    Martin, M.6
  • 6
    • 3843124444 scopus 로고    scopus 로고
    • Involvement of NKR-P2/NKG2D in DC-mediated killing of tumor targets: Indicative of a common, innate, targetrecognition paradigm?
    • Alli R, Savithri B, Das S, Varalakshmi C, Rangaraj N, Khar A. Involvement of NKR-P2/NKG2D in DC-mediated killing of tumor targets: Indicative of a common, innate, targetrecognition paradigm? Eur J Immunol. 2004;34: 1119-26.
    • (2004) Eur J Immunol , vol.34 , pp. 1119-1126
    • Alli, R.1    Savithri, B.2    Das, S.3    Varalakshmi, C.4    Rangaraj, N.5    Khar, A.6
  • 7
    • 41149173311 scopus 로고    scopus 로고
    • The promise of 4-1BB (CD137)-mediated immunomodulation and the immunotherapy of cancer
    • Lynch DH. The promise of 4-1BB (CD137)-mediated immunomodulation and the immunotherapy of cancer. Immunol Rev. 2008;222:277-86.
    • (2008) Immunol Rev , vol.222 , pp. 277-286
    • Lynch, D.H.1
  • 8
    • 63149163677 scopus 로고    scopus 로고
    • The role of TNF superfamily members in T-cell function and diseases
    • Croft M. The role of TNF superfamily members in T-cell function and diseases. Nat Rev Immunol. 2009;9:271-85.
    • (2009) Nat Rev Immunol , vol.9 , pp. 271-285
    • Croft, M.1
  • 9
    • 17644389199 scopus 로고    scopus 로고
    • TNF/TNFR family members in costimulation of T cell responses
    • Watts TH. TNF/TNFR family members in costimulation of T cell responses. Ann Rev Immunol. 2005;23:23-68.
    • (2005) Ann Rev Immunol , vol.23 , pp. 23-68
    • Watts, T.H.1
  • 10
    • 0032066764 scopus 로고    scopus 로고
    • Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells
    • Couderc B, Zitvogel L, Douin-Echinard V, Djennane L, Tahara H, Favre G, et al. Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells. Cancer Gene Ther. 1998;5:163-75.
    • (1998) Cancer Gene Ther , vol.5 , pp. 163-175
    • Couderc, B.1    Zitvogel, L.2    Douin-Echinard, V.3    Djennane, L.4    Tahara, H.5    Favre, G.6
  • 11
    • 0033134720 scopus 로고    scopus 로고
    • Anti-tumor immunity elicited by a recombinant vaccinia virus expressing CD70 (CD27L)
    • Lorenz MG, Kantor JA, Schlom J, Hodge JW. Anti-tumor immunity elicited by a recombinant vaccinia virus expressing CD70 (CD27L). Hum Gene Ther. 1999;10:1095-103.
    • (1999) Hum Gene Ther , vol.10 , pp. 1095-1103
    • Lorenz, M.G.1    Kantor, J.A.2    Schlom, J.3    Hodge, J.W.4
  • 13
    • 0035159948 scopus 로고    scopus 로고
    • B7H costimulates clonal expansion of, and cognate destruction of tumor cells by, CD8+ T lymphocytes in vivo
    • Liu X, Bai X-F, Wen J, Gao J-X, Liu J, Lu P, et al. B7H costimulates clonal expansion of, and cognate destruction of tumor cells by, CD8+ T lymphocytes in vivo. J Exp Med. 2001;194:1339-48.
    • (2001) J Exp Med , vol.194 , pp. 1339-1348
    • Liu, X.1    Bai, X.-F.2    Wen, J.3    Gao, J.-X.4    Liu, J.5    Lu, P.6
  • 14
    • 0035399581 scopus 로고    scopus 로고
    • Enhancement of CD8+ T cell responses by ICOS/B7h costimulation
    • Wallin JJ, Liang L, Bakardjiev A, Sha WC. Enhancement of CD8+ T cell responses by ICOS/B7h costimulation. J Immunol. 2001;167:132-9.
    • (2001) J Immunol , vol.167 , pp. 132-139
    • Wallin, J.J.1    Liang, L.2    Bakardjiev, A.3    Sha, W.C.4
  • 15
    • 33646419260 scopus 로고    scopus 로고
    • Agonist anti-GITR antibody enhances vaccine-induced CD8+ T-cell responses and tumor immunity
    • Cohen AD, Diab A, Perales M-A, Wolchok JD, Rizzuto G, Merghoub T, et al. Agonist anti-GITR antibody enhances vaccine-induced CD8+ T-cell responses and tumor immunity. Cancer Res. 2006;66:4904-12.
    • (2006) Cancer Res , vol.66 , pp. 4904-4912
    • Cohen, A.D.1    Diab, A.2    Perales, M.-A.3    Wolchok, J.D.4    Rizzuto, G.5    Merghoub, T.6
  • 16
    • 38849154553 scopus 로고    scopus 로고
    • Pivotal roles of CD4+ effector T cells in mediating agonistic anti-GITR mAb-induced-immune activation and tumor immunity in CT26 tumors
    • Zhou P, L'Italien L, Hodges D, Schebye XM. Pivotal roles of CD4+ effector T cells in mediating agonistic anti-GITR mAb-induced-immune activation and tumor immunity in CT26 tumors. J Immunol. 2007;179:7365-75.
    • (2007) J Immunol , vol.179 , pp. 7365-7375
    • Zhou, P.1    L'Italien, L.2    Hodges, D.3    Schebye, X.M.4
  • 17
    • 0030766236 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression. A role in the immune tolerance to antigenic tumors
    • Chaux P, Favre N, Bonnotte B, Moutet M, Martin M, Martin F. Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression. A role in the immune tolerance to antigenic tumors. Adv Exp Med Biol. 1997;417:525-8.
    • (1997) Adv Exp Med Biol , vol.417 , pp. 525-528
    • Chaux, P.1    Favre, N.2    Bonnotte, B.3    Moutet, M.4    Martin, M.5    Martin, F.6
  • 18
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptideor tumor lysate-pulsed dendritic cells
    • Nestle FO, Alijagic S, Gilliet M, Sun Y, Grabbe S, Dummer R, et al. Vaccination of melanoma patients with peptideor tumor lysate-pulsed dendritic cells. Nat Med. 1998;4: 328-32.
    • (1998) Nat Med , vol.4 , pp. 328-332
    • Nestle, F.O.1    Alijagic, S.2    Gilliet, M.3    Sun, Y.4    Grabbe, S.5    Dummer, R.6
  • 20
    • 70350494714 scopus 로고    scopus 로고
    • Immune responses in patients with metastatic renal cell carcinoma treated with dendritic cells pulsed with tumor lysate
    • Soleimani A, Berntsen A, Svane IM, Pedersen AE. Immune responses in patients with metastatic renal cell carcinoma treated with dendritic cells pulsed with tumor lysate. Scand J Immunol. 2009;70:481-9.
    • (2009) Scand J Immunol , vol.70 , pp. 481-489
    • Soleimani, A.1    Berntsen, A.2    Svane, I.M.3    Pedersen, A.E.4
  • 21
    • 0037431558 scopus 로고    scopus 로고
    • Clinical and immunological evaluation of patients with metastatic melanoma undergoing immunization with the HLA-Cw * 0702-associated epitope MAGE-A12: 170-178
    • Bettinotti M, Panelli MC, Ruppe E, Mocellin S, Phan GQ, White DE, Marincola FM. Clinical and immunological evaluation of patients with metastatic melanoma undergoing immunization with the HLA-Cw * 0702-associated epitope MAGE-A12:170-178. Int J Cancer. 2003;105:210-6.
    • (2003) Int J Cancer , vol.105 , pp. 210-216
    • Bettinotti, M.1    Panelli, M.C.2    Ruppe, E.3    Mocellin, S.4    Phan, G.Q.5    White, D.E.6    Marincola, F.M.7
  • 22
    • 0030048724 scopus 로고    scopus 로고
    • Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
    • Celluzzi CM, Mayordomo JI, Storkus WJ, Lotze MT, Falo LD Jr. Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity. J Exp Med. 1996;183:283-7.
    • (1996) J Exp Med , vol.183 , pp. 283-287
    • Celluzzi, C.M.1    Mayordomo, J.I.2    Storkus, W.J.3    Lotze, M.T.4    Falo Jr., L.D.5
  • 23
    • 0036659913 scopus 로고    scopus 로고
    • Antigen-bearing immature dendritic cells induce peptide-specific CD8(+ ) regulatory T cells in vivo in humans
    • Dhodapkar MV, Steinman RM. Antigen-bearing immature dendritic cells induce peptide-specific CD8(+ ) regulatory T cells in vivo in humans. Blood. 2002;100:174-7.
    • (2002) Blood , vol.100 , pp. 174-177
    • Dhodapkar, M.V.1    Steinman, R.M.2
  • 25
    • 0028793675 scopus 로고
    • Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity
    • Mayordomo JI, Zorina T, Storkus WJ, Zitvogel L, Celluzzi C, Falo LD, et al. Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity. Nat Med. 1995;1: 1297-302.
    • (1995) Nat Med , vol.1 , pp. 1297-1302
    • Mayordomo, J.I.1    Zorina, T.2    Storkus, W.J.3    Zitvogel, L.4    Celluzzi, C.5    Falo, L.D.6
  • 26
    • 0033516548 scopus 로고    scopus 로고
    • Induction of carcinoembryonic antigen (CEA)-specific cytotoxic T-lymphocyte responses in vitro using autologous dendritic cells loaded with CEA peptide or CEA RNA in patients with metastatic malignancies expressing CEA
    • Nair SK, Hull S, Coleman D, Gilboa E, Lyerly HK, Morse MA. Induction of carcinoembryonic antigen (CEA)-specific cytotoxic T-lymphocyte responses in vitro using autologous dendritic cells loaded with CEA peptide or CEA RNA in patients with metastatic malignancies expressing CEA. Int J Cancer. 1999;82:121-4.
    • (1999) Int J Cancer , vol.82 , pp. 121-124
    • Nair, S.K.1    Hull, S.2    Coleman, D.3    Gilboa, E.4    Lyerly, H.K.5    Morse, M.A.6
  • 27
    • 0034665304 scopus 로고    scopus 로고
    • Mage-3 and infl uenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocytederived dendritic cells
    • Schuler-Thurner B, Dieckmann D, Keikavoussi P, Bender A, Maczek C, Jonuleit H, et al. Mage-3 and infl uenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocytederived dendritic cells. J Immunol. 2000;165:3492-6.
    • (2000) J Immunol , vol.165 , pp. 3492-3496
    • Schuler-Thurner, B.1    Dieckmann, D.2    Keikavoussi, P.3    Bender, A.4    Maczek, C.5    Jonuleit, H.6
  • 28
    • 0033405438 scopus 로고    scopus 로고
    • Vaccination with mage-3A1 peptidepulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
    • Thurner B, Haendle I, Roder C, Dieckmann D, Keikavoussi P, Jonuleit H, et al. Vaccination with mage-3A1 peptidepulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J Exp Med. 1999;190:1669-78.
    • (1999) J Exp Med , vol.190 , pp. 1669-1678
    • Thurner, B.1    Haendle, I.2    Roder, C.3    Dieckmann, D.4    Keikavoussi, P.5    Jonuleit, H.6
  • 29
    • 0028979830 scopus 로고
    • Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells
    • Mukherji B, Chakraborty NG, Yamasaki S, Okino T, Yamase H, Sporn JR, et al. Induction of antigen-specific cytolytic T cells in situ in human melanoma by immunization with synthetic peptide-pulsed autologous antigen presenting cells. Proc Natl Acad Sci USA. 1995;92:8078-82.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8078-8082
    • Mukherji, B.1    Chakraborty, N.G.2    Yamasaki, S.3    Okino, T.4    Yamase, H.5    Sporn, J.R.6
  • 30
    • 33645325115 scopus 로고    scopus 로고
    • Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: A randomized phase III trial of the DC study group of the DeCOG
    • Schadendorf D, Ugurel S, Schuler-Thurner B, Nestle FO, Enk A, Brocker EB, et al. Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: A randomized phase III trial of the DC study group of the DeCOG. Ann Oncol. 2006;17:563-70.
    • (2006) Ann Oncol , vol.17 , pp. 563-570
    • Schadendorf, D.1    Ugurel, S.2    Schuler-Thurner, B.3    Nestle, F.O.4    Enk, A.5    Brocker, E.B.6
  • 31
    • 0642311904 scopus 로고    scopus 로고
    • Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells
    • Slingluff CL Jr, Petroni GR, Yamshchikov GV, Barnd DL, Eastham S, Galavotti H, et al. Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells. J Clin Oncol. 2003;21:4016-26.
    • (2003) J Clin Oncol , vol.21 , pp. 4016-4026
    • Slingluff Jr., C.L.1    Petroni, G.R.2    Yamshchikov, G.V.3    Barnd, D.L.4    Eastham, S.5    Galavotti, H.6
  • 32
    • 0034181264 scopus 로고    scopus 로고
    • Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+ ) hematopoietic progenitor cells
    • Mackensen A, Herbst B, Chen JL, Kohler G, Noppen C, Herr W, et al. Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+ ) hematopoietic progenitor cells. Int J Cancer. 2000;86:385-92.
    • (2000) Int J Cancer , vol.86 , pp. 385-392
    • Mackensen, A.1    Herbst, B.2    Chen, J.L.3    Kohler, G.4    Noppen, C.5    Herr, W.6
  • 33
    • 0030470404 scopus 로고    scopus 로고
    • Phase I clinical trial: T-cell therapy for prostate cancer using autologous dendritic cells pulsed with HLA-A0201-specific peptides from prostate-specific membrane antigen
    • Murphy G, Tjoa B, Ragde H, Kenny G, Boynton A. Phase I clinical trial: T-cell therapy for prostate cancer using autologous dendritic cells pulsed with HLA-A0201-specific peptides from prostate-specific membrane antigen. Prostate. 1996;29:371-80.
    • (1996) Prostate , vol.29 , pp. 371-380
    • Murphy, G.1    Tjoa, B.2    Ragde, H.3    Kenny, G.4    Boynton, A.5
  • 34
    • 0033934224 scopus 로고    scopus 로고
    • Phase 1 study in patients with metastatic melanoma of immunization with dendritic cells presenting epitopes derived from the melanoma-associated antigens MART-1 and gp100
    • Panelli MC, Wunderlich J, Jeffries J, Wang E, Mixon A, Rosenberg SA, et al. Phase 1 study in patients with metastatic melanoma of immunization with dendritic cells presenting epitopes derived from the melanoma-associated antigens MART-1 and gp100. J Immunother (1997). 2000; 23:487-98.
    • (2000) J Immunother (1997) , vol.23 , pp. 487-498
    • Panelli, M.C.1    Wunderlich, J.2    Jeffries, J.3    Wang, E.4    Mixon, A.5    Rosenberg, S.A.6
  • 35
    • 77957319524 scopus 로고    scopus 로고
    • Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: Results from a phase I/II trial
    • Trepiakas R, Berntsen A, Hadrup SR, Bjø r n J, Geertsen PF, Straten PT, et al. Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: Results from a phase I/II trial. Cytotherapy. 2010;12:1-14.
    • (2010) Cytotherapy , vol.12 , pp. 1-14
    • Trepiakas, R.1    Berntsen, A.2    Hadrup, S.R.3    Bjørn, J.4    Geertsen, P.F.5    Straten, P.T.6
  • 36
    • 0034652624 scopus 로고    scopus 로고
    • Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplifi ed from tumor cells
    • Boczkowski D, Nair SK, Nam J-H, Lyerly HK, Gilboa E. Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplifi ed from tumor cells. Cancer Res. 2000;60: 1028-34.
    • (2000) Cancer Res , vol.60 , pp. 1028-1034
    • Boczkowski, D.1    Nair, S.K.2    Nam, J.-H.3    Lyerly, H.K.4    Gilboa, E.5
  • 37
    • 0029839058 scopus 로고    scopus 로고
    • Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo
    • Boczkowski D, Nair SK, Snyder D, Gilboa E. Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. J Exp Med. 1996;184:465-72.
    • (1996) J Exp Med , vol.184 , pp. 465-472
    • Boczkowski, D.1    Nair, S.K.2    Snyder, D.3    Gilboa, E.4
  • 38
    • 0035870244 scopus 로고    scopus 로고
    • Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T-cell responses against antigens expressed by primary and metastatic tumors
    • Heiser A, Maurice MA, Yancey DR, Coleman DM, Dahm P, Vieweg J. Human dendritic cells transfected with renal tumor RNA stimulate polyclonal T-cell responses against antigens expressed by primary and metastatic tumors. Cancer Res. 2001;61:3388-93.
    • (2001) Cancer Res , vol.61 , pp. 3388-3393
    • Heiser, A.1    Maurice, M.A.2    Yancey, D.R.3    Coleman, D.M.4    Dahm, P.5    Vieweg, J.6
  • 39
    • 0035284901 scopus 로고    scopus 로고
    • Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplifi ed tumor RNA
    • Heiser A, Maurice MA, Yancey DR, Wu NZ, Dahm P, Pruitt SK, et al. Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with amplifi ed tumor RNA. J Immunol. 2001;166:2953-60.
    • (2001) J Immunol , vol.166 , pp. 2953-2960
    • Heiser, A.1    Maurice, M.A.2    Yancey, D.R.3    Wu, N.Z.4    Dahm, P.5    Pruitt, S.K.6
  • 41
    • 33746910738 scopus 로고    scopus 로고
    • Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
    • Kyte JA, Mu L, Aamdal S, Kvalheim G, Dueland S, Hauser M, et al. Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA. Cancer Gene Ther. 2006;13:905-18.
    • (2006) Cancer Gene Ther , vol.13 , pp. 905-918
    • Kyte, J.A.1    Mu, L.2    Aamdal, S.3    Kvalheim, G.4    Dueland, S.5    Hauser, M.6
  • 42
    • 0038066552 scopus 로고    scopus 로고
    • Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells
    • Su Z, Dannull J, Heiser A, Yancey D, Pruitt S, Madden J, et al. Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumor RNA-transfected dendritic cells. Cancer Res. 2003;63:2127-33.
    • (2003) Cancer Res , vol.63 , pp. 2127-2133
    • Su, Z.1    Dannull, J.2    Heiser, A.3    Yancey, D.4    Pruitt, S.5    Madden, J.6
  • 43
    • 0036133166 scopus 로고    scopus 로고
    • MRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT)
    • Jan 1
    • Saebøe-Larssen S, Fossberg E, Gaudernack G. mRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT). J Immunol Methods. 2002 Jan 1;259(1-2):191-203.
    • (2002) J Immunol Methods , vol.259 , Issue.1-2 , pp. 191-203
    • Saebøe-Larssen, S.1    Fossberg, E.2    Gaudernack, G.3
  • 44
    • 20144364773 scopus 로고    scopus 로고
    • Telomerase mRNA-transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer
    • Su Z, Dannull J, Yang BK, Dahm P, Coleman D, Yancey D, et al. Telomerase mRNA-transfected dendritic cells stimulate antigen-specific CD8+ and CD4+ T cell responses in patients with metastatic prostate cancer. J Immunol. 2005;174: 3798-807.
    • (2005) J Immunol , vol.174 , pp. 3798-3807
    • Su, Z.1    Dannull, J.2    Yang, B.K.3    Dahm, P.4    Coleman, D.5    Yancey, D.6
  • 45
    • 0141564862 scopus 로고    scopus 로고
    • Induction of infl uenza matrix protein 1 and MelanA-specific T lymphocytes in vitro using mRNA-electroporated dendritic cells
    • Sep
    • Tuyaerts S, Michiels A, Corthals J, Bonehill A, Heirman C, Greef CD, et al. Induction of infl uenza matrix protein 1 and MelanA-specific T lymphocytes in vitro using mRNA-electroporated dendritic cells. Cancer Gene Ther. 2003 Sep; 10(9):696-706.
    • (2003) Cancer Gene Ther , vol.10 , Issue.9 , pp. 696-706
    • Tuyaerts, S.1    Michiels, A.2    Corthals, J.3    Bonehill, A.4    Heirman, C.5    Greef, C.D.6
  • 46
    • 78650992314 scopus 로고    scopus 로고
    • High immunogenic potential of p53 mRNA-transfected dendritic cells in patients with primary breast cancer
    • Jan
    • Met Ö, Balslev E, Flyger H, Svane I. High immunogenic potential of p53 mRNA-transfected dendritic cells in patients with primary breast cancer. Breast Cancer Res Treat. 2011 Jan;125(2):395-406.
    • (2011) Breast Cancer Res Treat , vol.125 , Issue.2 , pp. 395-406
    • Met, Ö.1    Balslev, E.2    Flyger, H.3    Svane, I.4
  • 47
    • 1242306187 scopus 로고    scopus 로고
    • Dendritic cell subsets generated from CD34+ hematopoietic progenitors can be transfected with mRNA and induce antigen-specific cytotoxic T cell responses * 1
    • Ueno H, Tcherepanova I, Reygrobellet O, Laughner E, Ventura C, Palucka AK, et al. Dendritic cell subsets generated from CD34+ hematopoietic progenitors can be transfected with mRNA and induce antigen-specific cytotoxic T cell responses * 1. J Immunol Meth. 2004;285:171-80.
    • (2004) J Immunol Meth , vol.285 , pp. 171-180
    • Ueno, H.1    Tcherepanova, I.2    Reygrobellet, O.3    Laughner, E.4    Ventura, C.5    Palucka, A.K.6
  • 48
    • 0035412401 scopus 로고    scopus 로고
    • Highly effi cient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
    • Van Tendeloo VF, Ponsaerts P, Lardon F, Nijs G, Lenjou M, Van Broeckhoven C, et al. Highly effi cient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood. 2001;98:49-56.
    • (2001) Blood , vol.98 , pp. 49-56
    • Van Tendeloo, V.F.1    Ponsaerts, P.2    Lardon, F.3    Nijs, G.4    Lenjou, M.5    Van Broeckhoven, C.6
  • 50
    • 0035889647 scopus 로고    scopus 로고
    • Active immunization against cancer with dendritic cells: The near future
    • Steinman RM, Dhodapkar M. Active immunization against cancer with dendritic cells: The near future. Int J Cancer. 2001;94:459-73.
    • (2001) Int J Cancer , vol.94 , pp. 459-473
    • Steinman, R.M.1    Dhodapkar, M.2
  • 51
    • 0028208910 scopus 로고
    • Effective tumor vaccine generated by fusion of hepatoma cells with activated B cells
    • Guo Y, Wu M, Chen H, Wang X, Liu G, Li G, et al. Effective tumor vaccine generated by fusion of hepatoma cells with activated B cells. Science. 1994;263:518-20.
    • (1994) Science , vol.263 , pp. 518-520
    • Guo, Y.1    Wu, M.2    Chen, H.3    Wang, X.4    Liu, G.5    Li, G.6
  • 52
    • 0030904482 scopus 로고    scopus 로고
    • Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells
    • Gong J, Chen D, Kashiwaba M, Kufe D. Induction of antitumor activity by immunization with fusions of dendritic and carcinoma cells. Nat Med. 1997;3:558-61.
    • (1997) Nat Med , vol.3 , pp. 558-561
    • Gong, J.1    Chen, D.2    Kashiwaba, M.3    Kufe, D.4
  • 53
    • 0016937419 scopus 로고
    • Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol
    • Davidson RL, Gerald PS. Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol. Somatic Cell Genet. 1976;2:165-76.
    • (1976) Somatic Cell Genet , vol.2 , pp. 165-176
    • Davidson, R.L.1    Gerald, P.S.2
  • 54
    • 0021365383 scopus 로고
    • Electrofusion. A new, highly effi cient technique for generating somatic cell hybrids
    • Finaz C, Lefevre A, Teissie J. Electrofusion. A new, highly effi cient technique for generating somatic cell hybrids. Exp Cell Res. 1984;150:477-82.
    • (1984) Exp Cell Res , vol.150 , pp. 477-482
    • Finaz, C.1    Lefevre, A.2    Teissie, J.3
  • 55
    • 0035129816 scopus 로고    scopus 로고
    • Antitumor effect of immunizations with fusions of dendritic and glioma cells in a mouse brain tumor model
    • Akasaki YKT, Homma S, Abe T, Kofe D, Ohno T. Antitumor effect of immunizations with fusions of dendritic and glioma cells in a mouse brain tumor model. J Immunother. 2001;24: 106-13.
    • (2001) J Immunother , vol.24 , pp. 106-113
    • Akasaki, Y.K.T.1    Homma, S.2    Abe, T.3    Kofe, D.4    Ohno, T.5
  • 57
    • 0036992163 scopus 로고    scopus 로고
    • Tumour cell-dendritic cell fusion for cancer immunotherapy: Comparison of therapeutic effi ciency of polyethylene-glycol versus electro-fusion protocols
    • Lindner M, Schirrmacher V. Tumour cell-dendritic cell fusion for cancer immunotherapy: Comparison of therapeutic effi ciency of polyethylene-glycol versus electro-fusion protocols. Eur J Clin Invest. 2002;32:207-17.
    • (2002) Eur J Clin Invest , vol.32 , pp. 207-217
    • Lindner, M.1    Schirrmacher, V.2
  • 58
    • 0035841263 scopus 로고    scopus 로고
    • Electrofusion of a weakly immunogenic neuroblastoma with dendritic cells produces a tumor vaccine
    • Orentas RJ, Schauer D, Bin Q, Johnson BD. Electrofusion of a weakly immunogenic neuroblastoma with dendritic cells produces a tumor vaccine. Cellular Immunol. 2001;213:4-13.
    • (2001) Cellular Immunol , vol.213 , pp. 4-13
    • Orentas, R.J.1    Schauer, D.2    Bin, Q.3    Johnson, B.D.4
  • 59
    • 0032781867 scopus 로고    scopus 로고
    • Therapy of established tumour with a hybrid cellular vaccine generated by using granulocyte-macrophage colonystimulating factor genetically modifi ed dendritic cells
    • Cao X, Zhang W, Wang J, Huang X, Hamada H, Chen W, et al. Therapy of established tumour with a hybrid cellular vaccine generated by using granulocyte-macrophage colonystimulating factor genetically modifi ed dendritic cells. Immunology. 1999;97:616-25.
    • (1999) Immunology , vol.97 , pp. 616-625
    • Cao, X.1    Zhang, W.2    Wang, J.3    Huang, X.4    Hamada, H.5    Chen, W.6
  • 60
    • 0038612969 scopus 로고    scopus 로고
    • Vaccination of fusion cells of rat dendritic and carcinoma cells prevents tumor growth in vivo
    • Kawada M, Ikeda H, Takahashi T, Ishizu A, Ishikura H, Katoh H, et al. Vaccination of fusion cells of rat dendritic and carcinoma cells prevents tumor growth in vivo. Int J Cancer. 2003;105:520-6.
    • (2003) Int J Cancer , vol.105 , pp. 520-526
    • Kawada, M.1    Ikeda, H.2    Takahashi, T.3    Ishizu, A.4    Ishikura, H.5    Katoh, H.6
  • 63
    • 0032533837 scopus 로고    scopus 로고
    • Eliciting T cell immunity against poorly immunogenic tumors by immunization with dendritic cell-tumor fusion vaccines
    • Wang J, Saffold S, Cao X, Krauss J, Chen W. Eliciting T cell immunity against poorly immunogenic tumors by immunization with dendritic cell-tumor fusion vaccines. J Immunol. 1998;161:5516-24.
    • (1998) J Immunol , vol.161 , pp. 5516-5524
    • Wang, J.1    Saffold, S.2    Cao, X.3    Krauss, J.4    Chen, W.5
  • 64
    • 0037347935 scopus 로고    scopus 로고
    • Antitumor immunopreventive and immunotherapeutic effect in mice induced by hybrid vaccine of dendritic cells and hepatocarcinoma in vivo
    • Zhang JK, Li J, Zhang J, Chen HB, Chen SB. Antitumor immunopreventive and immunotherapeutic effect in mice induced by hybrid vaccine of dendritic cells and hepatocarcinoma in vivo. World J Gastroenterol. 2003;9:479-84.
    • (2003) World J Gastroenterol , vol.9 , pp. 479-484
    • Zhang, J.K.1    Li, J.2    Zhang, J.3    Chen, H.B.4    Chen, S.B.5
  • 65
    • 0036305621 scopus 로고    scopus 로고
    • Eliciting cytotoxic T lymphocytes against acute myeloid leukemia-derived antigens: Evaluation of dendritic cell-leukemia cell hybrids and other antigen-loading strategies for dendritic cell-based vaccination
    • Galea-Lauri J, Darling D, Mufti G, Harrison P, Farzaneh F. Eliciting cytotoxic T lymphocytes against acute myeloid leukemia-derived antigens: Evaluation of dendritic cell-leukemia cell hybrids and other antigen-loading strategies for dendritic cell-based vaccination. Cancer Immunol Immunother. 2002;51:299-310.
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 299-310
    • Galea-Lauri, J.1    Darling, D.2    Mufti, G.3    Harrison, P.4    Farzaneh, F.5
  • 66
    • 0037851825 scopus 로고    scopus 로고
    • Dendritic cells loaded with apoptotic tumour cells induce a stronger T-cell response than dendritic cell-tumour hybrids in B-CLL
    • Kokhaei P, Rezvany MR, Virving L, Choudhury A, Rabbani H, Osterborg A, et al. Dendritic cells loaded with apoptotic tumour cells induce a stronger T-cell response than dendritic cell-tumour hybrids in B-CLL. Leukemia. 2003;17:894-9.
    • (2003) Leukemia , vol.17 , pp. 894-899
    • Kokhaei, P.1    Rezvany, M.R.2    Virving, L.3    Choudhury, A.4    Rabbani, H.5    Osterborg, A.6
  • 67
    • 3042600552 scopus 로고    scopus 로고
    • Comparative analysis of antigen loading strategies of dendritic cells for tumor immunotherapy
    • Shimizu K, Kuriyama H, Kjaergaard J, Lee W, Tanaka H, Shu S. Comparative analysis of antigen loading strategies of dendritic cells for tumor immunotherapy. J Immunother. 2004;27:265-72.
    • (2004) J Immunother , vol.27 , pp. 265-272
    • Shimizu, K.1    Kuriyama, H.2    Kjaergaard, J.3    Lee, W.4    Tanaka, H.5    Shu, S.6
  • 68
    • 34250180058 scopus 로고    scopus 로고
    • Dendritic cell-tumor cell hybrids enhance the induction of cytotoxic T lymphocytes against murine colon cancer: A comparative analysis of antigen loading methods for the vaccination of immunotherapeutic dendritic cells
    • Yasuda T, Kamigaki T, Nakamura T, Imanishi T, Hayashi S, Kawasaki K, et al. Dendritic cell-tumor cell hybrids enhance the induction of cytotoxic T lymphocytes against murine colon cancer: A comparative analysis of antigen loading methods for the vaccination of immunotherapeutic dendritic cells. Oncol Rep. 2006;16:1317-24.
    • (2006) Oncol Rep , vol.16 , pp. 1317-1324
    • Yasuda, T.1    Kamigaki, T.2    Nakamura, T.3    Imanishi, T.4    Hayashi, S.5    Kawasaki, K.6
  • 69
    • 25444521270 scopus 로고    scopus 로고
    • Superior efficacy of dendritic cell-tumor fusion vaccine compared with tumor lysate-pulsed dendritic cell vaccine in colon cancer
    • Kao JY, Zhang M, Chen CM, Chen JJ. Superior efficacy of dendritic cell-tumor fusion vaccine compared with tumor lysate-pulsed dendritic cell vaccine in colon cancer. Immunol Lett. 2005;101:154-9.
    • (2005) Immunol Lett , vol.101 , pp. 154-159
    • Kao, J.Y.1    Zhang, M.2    Chen, C.M.3    Chen, JJ.4
  • 70
    • 34247618729 scopus 로고    scopus 로고
    • Effi cient activation of autologous tumor-specific T cells: A simple coculture technique of autologous dendritic cells compared to established cell fusion strategies in primary human colorectal carcinoma
    • Draube A, Beyer M, Schumer S, Thomas RK, Tresckow B, Koslowsky TC, et al. Effi cient activation of autologous tumor-specific T cells: A simple coculture technique of autologous dendritic cells compared to established cell fusion strategies in primary human colorectal carcinoma. J Immunother (1997). 2007;30:359-69.
    • (1997) J Immunother ( , vol.2007 , Issue.30 , pp. 359-369
    • Draube, A.1    Beyer, M.2    Schumer, S.3    Thomas, R.K.4    Tresckow, B.5    Koslowsky, T.C.6
  • 71
    • 12444273596 scopus 로고    scopus 로고
    • Induction of impaired antitumor immunity by fusion of MHC class IIdefi cient dendritic cells with tumor cells
    • Tanaka Y, Koido S, Ohana M, Liu C, Gong J. Induction of impaired antitumor immunity by fusion of MHC class IIdefi cient dendritic cells with tumor cells. J Immunol. 2005; 174:1274-80.
    • (2005) J Immunol , vol.174 , pp. 1274-1280
    • Tanaka, Y.1    Koido, S.2    Ohana, M.3    Liu, C.4    Gong, J.5
  • 72
    • 4344631824 scopus 로고    scopus 로고
    • Anti-tumor effects of dendritic and tumor cell fusions are not dependent on expression of MHC class I and II by dendritic cells
    • Takagi Y, Kikuchi T, Niimura M, Ohno T. Anti-tumor effects of dendritic and tumor cell fusions are not dependent on expression of MHC class I and II by dendritic cells. Cancer Lett. 2004;213:49-55.
    • (2004) Cancer Lett , vol.213 , pp. 49-55
    • Takagi, Y.1    Kikuchi, T.2    Niimura, M.3    Ohno, T.4
  • 73
    • 0037442132 scopus 로고    scopus 로고
    • Prevention of spontaneous breast carcinoma by prophylactic vaccination with dendritic/tumor fusion cells
    • Xia J, Tanaka Y, Koido S, Liu C, Mukherjee P, Gendler SJ, et al. Prevention of spontaneous breast carcinoma by prophylactic vaccination with dendritic/tumor fusion cells. J Immunol. 2003;170:1980-6.
    • (2003) J Immunol , vol.170 , pp. 1980-1986
    • Xia, J.1    Tanaka, Y.2    Koido, S.3    Liu, C.4    Mukherjee, P.5    Gendler, S.J.6
  • 74
    • 0035181956 scopus 로고    scopus 로고
    • Vaccination with allogeneic dendritic cells fused to carcinoma cells induces antitumor immunity in MUC1 transgenic mice
    • Tanaka Y, Koido S, Chen D, Gendler SJ, Kufe D, Gong J. Vaccination with allogeneic dendritic cells fused to carcinoma cells induces antitumor immunity in MUC1 transgenic mice. Clin Immunol. 2001;101:192-200.
    • (2001) Clin Immunol , vol.101 , pp. 192-200
    • Tanaka, Y.1    Koido, S.2    Chen, D.3    Gendler, S.J.4    Kufe, D.5    Gong, J.6
  • 76
    • 0036877104 scopus 로고    scopus 로고
    • Therapeutic immune response induced by electrofusion of dendritic and tumor cells
    • Tanaka H, Shimizu K, Hayashi T, Shu S. Therapeutic immune response induced by electrofusion of dendritic and tumor cells. Cell Immunol. 2002;220:1-12.
    • (2002) Cell Immunol , vol.220 , pp. 1-12
    • Tanaka, H.1    Shimizu, K.2    Hayashi, T.3    Shu, S.4
  • 77
    • 0033661660 scopus 로고    scopus 로고
    • Selection and characterization of MUC1- specific CD8+ T cells from MUC1 transgenic mice immunized with dendritic-carcinoma fusion cells
    • Gong J, Apostolopoulos V, Chen D, Chen H, Koido S, Gendler SJ, et al. Selection and characterization of MUC1- specific CD8+ T cells from MUC1 transgenic mice immunized with dendritic-carcinoma fusion cells. Immunology. 2000;101:316-24.
    • (2000) Immunology , vol.101 , pp. 316-324
    • Gong, J.1    Apostolopoulos, V.2    Chen, D.3    Chen, H.4    Koido, S.5    Gendler, S.J.6
  • 78
    • 0036498593 scopus 로고    scopus 로고
    • The kinetics of in vivo priming of CD4 and CD8 T cells by dendritic/ tumor fusion cells in MUC1-transgenic mice
    • Koido S, Tanaka Y, Chen D, Kufe D, Gong J. The kinetics of in vivo priming of CD4 and CD8 T cells by dendritic/ tumor fusion cells in MUC1-transgenic mice. J Immunol. 2002;168:2111-7.
    • (2002) J Immunol , vol.168 , pp. 2111-2117
    • Koido, S.1    Tanaka, Y.2    Chen, D.3    Kufe, D.4    Gong, J.5
  • 79
    • 0036286494 scopus 로고    scopus 로고
    • Engineered fusion hybrid vaccine of IL-4 gene-modifi ed myeloma and relative mature dendritic cells enhances antitumor immunity
    • Liu Y, Zhang W, Chan T, Saxena A, Xiang J. Engineered fusion hybrid vaccine of IL-4 gene-modifi ed myeloma and relative mature dendritic cells enhances antitumor immunity. Leuk Res. 2002;26:757-63.
    • (2002) Leuk Res , vol.26 , pp. 757-763
    • Liu, Y.1    Zhang, W.2    Chan, T.3    Saxena, A.4    Xiang, J.5
  • 80
    • 0036529823 scopus 로고    scopus 로고
    • Immunization against murine multiple myeloma with fusions of dendritic and plasmacytoma cells is potentiated by interleukin 12
    • Gong J, Koido S, Chen D, Tanaka Y, Huang L, Avigan D, et al. Immunization against murine multiple myeloma with fusions of dendritic and plasmacytoma cells is potentiated by interleukin 12. Blood. 2002;99:2512-7.
    • (2002) Blood , vol.99 , pp. 2512-2517
    • Gong, J.1    Koido, S.2    Chen, D.3    Tanaka, Y.4    Huang, L.5    Avigan, D.6
  • 81
    • 0036334152 scopus 로고    scopus 로고
    • Immunogenicity and therapeutic efficacy of dendritic-tumor hybrid cells generated by electrofusion
    • Hayashi T, Tanaka H, Tanaka J, Wang R, Averbook BJ, Cohen PA, et al. Immunogenicity and therapeutic efficacy of dendritic-tumor hybrid cells generated by electrofusion. Clin Immunol. 2002;104:14-20.
    • (2002) Clin Immunol , vol.104 , pp. 14-20
    • Hayashi, T.1    Tanaka, H.2    Tanaka, J.3    Wang, R.4    Averbook, B.J.5    Cohen, P.A.6
  • 82
    • 33644843971 scopus 로고    scopus 로고
    • Superior protective and therapeutic effects of IL-12 and IL-18 gene-transduced dendritic neuroblastoma fusion cells on liver metastasis of murine neuroblastoma
    • Iinuma H, Okinaga K, Fukushima R, Inaba T, Iwasaki K, Okinaga A, et al. Superior protective and therapeutic effects of IL-12 and IL-18 gene-transduced dendritic neuroblastoma fusion cells on liver metastasis of murine neuroblastoma. J Immunol. 2006;176:3461-9.
    • (2006) J Immunol , vol.176 , pp. 3461-3469
    • Iinuma, H.1    Okinaga, K.2    Fukushima, R.3    Inaba, T.4    Iwasaki, K.5    Okinaga, A.6
  • 83
    • 33845337663 scopus 로고    scopus 로고
    • Comparative analysis of DC fused with tumor cells or transfected with tumor total RNA as potential cancer vaccines against hepatocellular carcinoma
    • Zhang HM, Zhang LW, Liu WC, Cheng J, Si XM, Ren J. Comparative analysis of DC fused with tumor cells or transfected with tumor total RNA as potential cancer vaccines against hepatocellular carcinoma. Cytotherapy. 2006;8:580-8.
    • (2006) Cytotherapy , vol.8 , pp. 580-588
    • Zhang, H.M.1    Zhang, L.W.2    Liu, W.C.3    Cheng, J.4    Si, X.M.5    Ren, J.6
  • 84
    • 34548017607 scopus 로고    scopus 로고
    • Mouse dendritic- endothelial cell hybrids and 4-1BB costimulation elicit antitumor effects mediated by broad antiangiogenic immunity
    • Ko E, Luo W, Peng L, Wang X, Ferrone S. Mouse dendritic- endothelial cell hybrids and 4-1BB costimulation elicit antitumor effects mediated by broad antiangiogenic immunity. Cancer Res. 2007;67:7875-84.
    • (2007) Cancer Res , vol.67 , pp. 7875-7884
    • Ko, E.1    Luo, W.2    Peng, L.3    Wang, X.4    Ferrone, S.5
  • 85
    • 24944552128 scopus 로고    scopus 로고
    • Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-tumor cell fusion vaccines
    • Kjaergaard J, Wang LX, Kuriyama H, Shu S, Plautz GE. Active immunotherapy for advanced intracranial murine tumors by using dendritic cell-tumor cell fusion vaccines. J Neurosurg. 2005;103:156-64.
    • (2005) J Neurosurg , vol.103 , pp. 156-164
    • Kjaergaard, J.1    Wang, L.X.2    Kuriyama, H.3    Shu, S.4    Plautz, G.E.5
  • 86
    • 0141705384 scopus 로고    scopus 로고
    • Immature dendritic cell/tumor cell fusions induce potent antitumour immunity
    • Takeda A, Homma S, Okamoto T, Kufe D, Ohno T. Immature dendritic cell/tumor cell fusions induce potent antitumour immunity. Eur J Clin Invest. 2003;33:897-904.
    • (2003) Eur J Clin Invest , vol.33 , pp. 897-904
    • Takeda, A.1    Homma, S.2    Okamoto, T.3    Kufe, D.4    Ohno, T.5
  • 87
    • 33646534173 scopus 로고    scopus 로고
    • Fusion of CpG-ODN-stimulating dendritic cells with Lewis lung cancer cells can enhance anti-tumor immune responses
    • Du Y-C, Lin P, Zhang J, Lu Y-R, Ning Q-Z, Wang Q. Fusion of CpG-ODN-stimulating dendritic cells with Lewis lung cancer cells can enhance anti-tumor immune responses. Tissue Antigens. 2006;67:368-76.
    • (2006) Tissue Antigens , vol.67 , pp. 368-376
    • Du, Y.-C.1    Lin, P.2    Zhang, J.3    Lu, Y.-R.4    Ning, Q.-Z.5    Wang, Q.6
  • 88
    • 33845927976 scopus 로고    scopus 로고
    • Streptococcal preparation OK-432 promotes fusion effi ciency and enhances induction of antigen-specific CTL by fusions of dendritic cells and colorectal cancer cells
    • Koido S, Hara E, Homma S, Torii A, Mitsunaga M, Yanagisawa S, et al. Streptococcal preparation OK-432 promotes fusion effi ciency and enhances induction of antigen-specific CTL by fusions of dendritic cells and colorectal cancer cells. J Immunol. 2007;178:613-22.
    • (2007) J Immunol , vol.178 , pp. 613-622
    • Koido, S.1    Hara, E.2    Homma, S.3    Torii, A.4    Mitsunaga, M.5    Yanagisawa, S.6
  • 89
    • 0037379315 scopus 로고    scopus 로고
    • Tumorderived TGF-beta reduces the efficacy of dendritic cell/ tumor fusion vaccine
    • Kao JY, Gong Y, Chen CM, Zheng QD, Chen JJ. Tumorderived TGF-beta reduces the efficacy of dendritic cell/ tumor fusion vaccine. J Immunol. 2003;170:3806-11.
    • (2003) J Immunol , vol.170 , pp. 3806-3811
    • Kao, J.Y.1    Gong, Y.2    Chen, C.M.3    Zheng, Q.D.4    Chen, J.J.5
  • 90
    • 41049089064 scopus 로고    scopus 로고
    • Enhancement of dendritic cell-tumor fusion vaccine potency by indoleaminepyrrole 2,3-dioxygenase inhibitor, 1-MT
    • May
    • Ou X, Cai S, Liu P, Zeng J, He Y, Wu X, et al. Enhancement of dendritic cell-tumor fusion vaccine potency by indoleaminepyrrole 2,3-dioxygenase inhibitor, 1-MT. J Cancer Res Clin Oncol. 2008 May;134(5):525-33.
    • (2008) J Cancer Res Clin Oncol , vol.134 , Issue.5 , pp. 525-533
    • Ou, X.1    Cai, S.2    Liu, P.3    Zeng, J.4    He, Y.5    Wu, X.6
  • 91
    • 34347255017 scopus 로고    scopus 로고
    • A combination hybrid-based vaccination/adoptive cellular therapy to prevent tumor growth by involvement of T cells
    • Savai R, Schermuly RT, Pullamsetti SS, Schneider M, Greschus S, Ghofrani HA, et al. A combination hybrid-based vaccination/adoptive cellular therapy to prevent tumor growth by involvement of T cells. Cancer Res. 2007;67:5443-53.
    • (2007) Cancer Res , vol.67 , pp. 5443-5453
    • Savai, R.1    Schermuly, R.T.2    Pullamsetti, S.S.3    Schneider, M.4    Greschus, S.5    Ghofrani, H.A.6
  • 92
    • 33646809020 scopus 로고    scopus 로고
    • Hybrid-primed lymphocytes and hybrid vaccination prevent tumor growth of Lewis lung carcinoma in mice
    • Savai R, Schermuly RT, Schneider M, Pullamsetti SS, Grimminger F, Seeger W, et al. Hybrid-primed lymphocytes and hybrid vaccination prevent tumor growth of Lewis lung carcinoma in mice. J Immunother. 2006;29:175-87.
    • (2006) J Immunother , vol.29 , pp. 175-187
    • Savai, R.1    Schermuly, R.T.2    Schneider, M.3    Pullamsetti, S.S.4    Grimminger, F.5    Seeger, W.6
  • 93
    • 77950861700 scopus 로고    scopus 로고
    • Dendritic and tumor cell fusions transduced with adenovirus encoding CD40L eradicate B-cell lymphoma and induce a Th17-type response
    • Alvarez E, Moga E, Barquinero J, Sierra J, Briones J. Dendritic and tumor cell fusions transduced with adenovirus encoding CD40L eradicate B-cell lymphoma and induce a Th17-type response. Gene Ther. 2010;17:469-77.
    • (2010) Gene Ther , vol.17 , pp. 469-477
    • Alvarez, E.1    Moga, E.2    Barquinero, J.3    Sierra, J.4    Briones, J.5
  • 94
    • 34247635231 scopus 로고    scopus 로고
    • Superior anti-tumor protection and therapeutic efficacy of vaccination with allogeneic and semiallogeneic dendritic cell/tumor cell fusion hybrids for murine colon adenocarcinoma
    • Yasuda T, Kamigaki T, Kawasaki K, Nakamura T, Yamamoto M, Kanemitsu K, et al. Superior anti-tumor protection and therapeutic efficacy of vaccination with allogeneic and semiallogeneic dendritic cell/tumor cell fusion hybrids for murine colon adenocarcinoma. Cancer Immunol Immunother. 2007;56:1025-36.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 1025-1036
    • Yasuda, T.1    Kamigaki, T.2    Kawasaki, K.3    Nakamura, T.4    Yamamoto, M.5    Kanemitsu, K.6
  • 95
    • 77950861300 scopus 로고    scopus 로고
    • Anti-tumor effects of fusion vaccine prepared by renal cell carcinoma 786-O cell line and peripheral blood dendritic cells of healthy volunteers in vitro and in human immune reconstituted SCID mice
    • Hu Z, Liu S, Mai X, Hu Z, Liu C. Anti-tumor effects of fusion vaccine prepared by renal cell carcinoma 786-O cell line and peripheral blood dendritic cells of healthy volunteers in vitro and in human immune reconstituted SCID mice. Cell Immunol. 2010;262:112-9.
    • (2010) Cell Immunol , vol.262 , pp. 112-119
    • Hu, Z.1    Liu, S.2    Mai, X.3    Hu, Z.4    Liu, C.5
  • 96
    • 77952135173 scopus 로고    scopus 로고
    • Dendritic cell/ tumor hybrids enhances therapeutic efficacy against colorectal cancer liver metastasis in SCID mice
    • Xu F, Ye Y-J, Liu W, Kong M, He Y, Wang S. Dendritic cell/ tumor hybrids enhances therapeutic efficacy against colorectal cancer liver metastasis in SCID mice. Scand J Gastroenterol. 2010;45:707-13.
    • (2010) Scand J Gastroenterol , vol.45 , pp. 707-713
    • Xu, F.1    Ye, Y.-J.2    Liu, W.3    Kong, M.4    He, Y.5    Wang, S.6
  • 97
    • 0034646220 scopus 로고    scopus 로고
    • Activation of antitumor cytotoxic T lymphocytes by fusions of human dendritic cells and breast carcinoma cells
    • Gong J, Avigan D, Chen D, Wu Z, Koido S, Kashiwaba M, et al. Activation of antitumor cytotoxic T lymphocytes by fusions of human dendritic cells and breast carcinoma cells. Proc Natl Acad Sci USA. 2000;97:2715-8.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2715-2718
    • Gong, J.1    Avigan, D.2    Chen, D.3    Wu, Z.4    Koido, S.5    Kashiwaba, M.6
  • 98
    • 0034254702 scopus 로고    scopus 로고
    • Fusions of human ovarian carcinoma cells with autologous or allogeneic dendritic cells induce antitumor immunity
    • Gong J, Nikrui N, Chen D, Koido S, Wu Z, Tanaka Y, et al. Fusions of human ovarian carcinoma cells with autologous or allogeneic dendritic cells induce antitumor immunity. J Immunol. 2000;165:1705-11.
    • (2000) J Immunol , vol.165 , pp. 1705-1711
    • Gong, J.1    Nikrui, N.2    Chen, D.3    Koido, S.4    Wu, Z.5    Tanaka, Y.6
  • 100
    • 3242666838 scopus 로고    scopus 로고
    • Generation of dendritic cell-tumor cell hybrids by electrofusion for clinical vaccine application
    • Aug
    • Trevor KT, Cover C, Ruiz YW, Akporiaye ET, Hersh EM, Landais D, et al. Generation of dendritic cell-tumor cell hybrids by electrofusion for clinical vaccine application. Cancer Immunol Immunother. 2004 Aug;53(8):705-14.
    • (2004) Cancer Immunol Immunother , vol.53 , Issue.8 , pp. 705-714
    • Trevor, K.T.1    Cover, C.2    Ruiz, Y.W.3    Akporiaye, E.T.4    Hersh, E.M.5    Landais, D.6
  • 101
    • 0036036401 scopus 로고    scopus 로고
    • Cell fusion: An approach to generating constitutively proliferating human tumor antigen-presenting cells
    • Jantscheff P, Spagnoli G, Zajac P, Rochlitz CF. Cell fusion: An approach to generating constitutively proliferating human tumor antigen-presenting cells. Cancer Immunol Immunother. 2002;51:367-75.
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 367-375
    • Jantscheff, P.1    Spagnoli, G.2    Zajac, P.3    Rochlitz, C.F.4
  • 102
    • 26644444784 scopus 로고    scopus 로고
    • Antitumor activity of a fusion of esophageal carcinoma cells with dendritic cells derived from cord blood
    • Guo G, Chen S, Zhang J, Luo L, Yu J, Dong H, et al. Antitumor activity of a fusion of esophageal carcinoma cells with dendritic cells derived from cord blood. Vaccine. 2005;23: 5225-30.
    • (2005) Vaccine , vol.23 , pp. 5225-5230
    • Guo, G.1    Chen, S.2    Zhang, J.3    Luo, L.4    Yu, J.5    Dong, H.6
  • 103
    • 77951878979 scopus 로고    scopus 로고
    • Dendritic/pancreatic carcinoma fusions for clinical use: Comparative functional analysis of healthy- versus patient-derived fusions
    • Koido S, Hara E, Homma S, Namiki Y, Komita H, Takahara A, et al. Dendritic/pancreatic carcinoma fusions for clinical use: Comparative functional analysis of healthy- versus patient-derived fusions. Clin Immunol. 2010;135:384-400.
    • (2010) Clin Immunol , vol.135 , pp. 384-400
    • Koido, S.1    Hara, E.2    Homma, S.3    Namiki, Y.4    Komita, H.5    Takahara, A.6
  • 104
    • 14844337815 scopus 로고    scopus 로고
    • Tumour-dendritic hybrid cell vaccination for the treatment of patients with malignant melanoma: Immunological effects and clinical results
    • Trefzer U, Herberth G, Wohlan K, Milling A, Thiemann M, Sharav T, et al. Tumour-dendritic hybrid cell vaccination for the treatment of patients with malignant melanoma: Immunological effects and clinical results. Vaccine. 2005;23: 2367-73.
    • (2005) Vaccine , vol.23 , pp. 2367-2373
    • Trefzer, U.1    Herberth, G.2    Wohlan, K.3    Milling, A.4    Thiemann, M.5    Sharav, T.6
  • 105
    • 0034100896 scopus 로고    scopus 로고
    • Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids
    • Kugler ASG, Walden P, Zöller G, Zobywalski A, Brossart P, Trefzer U, Ullrich S, et al. Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids. Nature Med. 2000;6:332-6.
    • (2000) Nature Med , vol.6 , pp. 332-336
    • Kugler, A.S.G.1    Walden, P.2    Zöller, G.3    Zobywalski, A.4    Brossart, P.5    Trefzer, U.6    Ullrich, S.7
  • 106
    • 0033950319 scopus 로고    scopus 로고
    • Hybrid cell vaccination for cancer immune therapy: First clinical trial with metastatic melanoma
    • Trefzer U, Weingart G, Chen Y, Herberth G, Adrian K, Winter H, et al. Hybrid cell vaccination for cancer immune therapy: First clinical trial with metastatic melanoma. Int J Cancer. 2000;85:618-26.
    • (2000) Int J Cancer , vol.85 , pp. 618-626
    • Trefzer, U.1    Weingart, G.2    Chen, Y.3    Herberth, G.4    Adrian, K.5    Winter, H.6
  • 107
    • 0037159684 scopus 로고    scopus 로고
    • Research misconduct. German inquiry finds flaws, not fraud
    • Bostanci A, Vogel G. Research misconduct. German inquiry finds flaws, not fraud. Science. 2002;298:1531-3.
    • (2002) Science , vol.298 , pp. 1531-1533
    • Bostanci, A.1    Vogel, G.2
  • 108
    • 0344393659 scopus 로고    scopus 로고
    • Immunotherapy using fusions of autologous dendritic cells and tumor cells showed effective clinical response in a patient with advanced gastric carcinoma
    • Homma S, Matai K, Irie M, Ohno T, Kufe D, Toda G. Immunotherapy using fusions of autologous dendritic cells and tumor cells showed effective clinical response in a patient with advanced gastric carcinoma. J Gastroenterol. 2003; 38:989-94.
    • (2003) J Gastroenterol , vol.38 , pp. 989-994
    • Homma, S.1    Matai, K.2    Irie, M.3    Ohno, T.4    Kufe, D.5    Toda, G.6
  • 109
    • 33645105886 scopus 로고    scopus 로고
    • Cancer immunotherapy using dendritic/tumour-fusion vaccine induces elevation of serum anti-nuclear antibody with better clinical responses
    • Homma S, Sagawa Y, Ito M, Ohno T, Toda G. Cancer immunotherapy using dendritic/tumour-fusion vaccine induces elevation of serum anti-nuclear antibody with better clinical responses. Clin Exp Immunol. 2006;144:41-7.
    • (2006) Clin Exp Immunol , vol.144 , pp. 41-47
    • Homma, S.1    Sagawa, Y.2    Ito, M.3    Ohno, T.4    Toda, G.5
  • 110
    • 0037457018 scopus 로고    scopus 로고
    • Allogeneic dendritic cells fused with tumor cells: Preclinical results and outcome of a clinical phase I/II trial in patients with metastatic renal cell carcinoma
    • Marten A, Renoth S, Heinicke T, Albers P, Pauli A, Mey U, et al. Allogeneic dendritic cells fused with tumor cells: Preclinical results and outcome of a clinical phase I/II trial in patients with metastatic renal cell carcinoma. Hum Gene Ther. 2003;14:483-94.
    • (2003) Hum Gene Ther , vol.14 , pp. 483-494
    • Marten, A.1    Renoth, S.2    Heinicke, T.3    Albers, P.4    Pauli, A.5    Mey, U.6
  • 111
    • 3242666031 scopus 로고    scopus 로고
    • Fusion cell vaccination of patients with metastatic breast and renal cancer induces immunological and clinical responses
    • Avigan D, Vasir B, Gong J, Borges V, Wu Z, Uhl L, et al. Fusion cell vaccination of patients with metastatic breast and renal cancer induces immunological and clinical responses. Clin Cancer Res. 2004;10:4699-708.
    • (2004) Clin Cancer Res , vol.10 , pp. 4699-4708
    • Avigan, D.1    Vasir, B.2    Gong, J.3    Borges, V.4    Wu, Z.5    Uhl, L.6
  • 112
    • 34748846272 scopus 로고    scopus 로고
    • Phase I/II study of vaccination with electrofused allogeneic dendritic cells/autologous tumorderived cells in patients with stage IV renal cell carcinoma
    • Avigan DE, Vasir B, George DJ, Oh WK, Atkins MB, McDermott DF, et al. Phase I/II study of vaccination with electrofused allogeneic dendritic cells/autologous tumorderived cells in patients with stage IV renal cell carcinoma. J Immunother (1997). 2007;30:749-61.
    • (1997) J Immunother , vol.2007 , Issue.30 , pp. 749-761
    • Avigan, D.E.1    Vasir, B.2    George, D.J.3    Oh, W.K.4    Atkins, M.B.5    McDermott, D.F.6
  • 113
    • 0034840181 scopus 로고    scopus 로고
    • Results of a phase I clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells
    • Kikuchi T, Akasaki Y, Irie M, Homma S, Abe T, Ohno T. Results of a phase I clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells. Cancer Immunol Immunother. 2001;50:337-44.
    • (2001) Cancer Immunol Immunother , vol.50 , pp. 337-344
    • Kikuchi, T.1    Akasaki, Y.2    Irie, M.3    Homma, S.4    Abe, T.5    Ohno, T.6
  • 115
    • 0028139342 scopus 로고
    • Recruitment of helper T cells for induction of tumour rejection by cytolytic T lymphocytes
    • Stuhler G, Walden P. Recruitment of helper T cells for induction of tumour rejection by cytolytic T lymphocytes. Cancer Immunol Immunother. 1994;39:342-5.
    • (1994) Cancer Immunol Immunother , vol.39 , pp. 342-345
    • Stuhler, G.1    Walden, P.2
  • 116
    • 0034234287 scopus 로고    scopus 로고
    • Peripheral burst of tumor-specific cytotoxic T lymphocytes and infi ltration of metastatic lesions by memory CD8+ T cells in melanoma patients receiving interleukin 12
    • Mortarini R, Borri A, Tragni G, Bersani I, Vegetti C, Bajetta E, et al. Peripheral burst of tumor-specific cytotoxic T lymphocytes and infi ltration of metastatic lesions by memory CD8+ T cells in melanoma patients receiving interleukin 12. Cancer Res. 2000;60:3559-68.
    • (2000) Cancer Res , vol.60 , pp. 3559-3568
    • Mortarini, R.1    Borri, A.2    Tragni, G.3    Bersani, I.4    Vegetti, C.5    Bajetta, E.6
  • 117
    • 7444220033 scopus 로고    scopus 로고
    • Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12
    • Kikuchi T, Akasaki Y, Abe T, Fukuda T, Saotome H, Ryan JL, et al. Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12. J Immunother (1997). 2004;27:452-9.
    • (1997) J Immunother ( , vol.2004 , Issue.27 , pp. 452-459
    • Kikuchi, T.1    Akasaki, Y.2    Abe, T.3    Fukuda, T.4    Saotome, H.5    Ryan, J.L.6
  • 118
    • 33645222947 scopus 로고    scopus 로고
    • Dendritoma vaccination combined with low dose interleukin- 2 in metastatic melanoma patients induced immunological and clinical responses
    • Wei Y, Sticca RP, Holmes LM, Burgin KE, Li J, Williamson J, et al. Dendritoma vaccination combined with low dose interleukin- 2 in metastatic melanoma patients induced immunological and clinical responses. Int J Oncol. 2006;28:585-93.
    • (2006) Int J Oncol , vol.28 , pp. 585-593
    • Wei, Y.1    Sticca, R.P.2    Holmes, L.M.3    Burgin, K.E.4    Li, J.5    Williamson, J.6
  • 119
    • 1442336031 scopus 로고    scopus 로고
    • Hybrid cell vaccination in metastatic melanoma: Clinical and immunologic results of a phase I/II study
    • Haenssle HA, Krause SW, Emmert S, Zutt M, Kretschmer L, Schmidberger H, et al. Hybrid cell vaccination in metastatic melanoma: Clinical and immunologic results of a phase I/II study. J Immunother. 2004;27:147-55.
    • (2004) J Immunother , vol.27 , pp. 147-155
    • Haenssle, H.A.1    Krause, S.W.2    Emmert, S.3    Zutt, M.4    Kretschmer, L.5    Schmidberger, H.6
  • 120
    • 23944436355 scopus 로고    scopus 로고
    • Antitumor response against myeloma cells by immunization with mouse syngenic dendritoma
    • Queant S, Sarde CO, Gobert MG, Kadouche J, Roseto A. Antitumor response against myeloma cells by immunization with mouse syngenic dendritoma. Hybridoma (Larchmt). 2005;24:182-8.
    • (2005) Hybridoma (Larchmt) , vol.24 , pp. 182-188
    • Queant, S.1    Sarde, C.O.2    Gobert, M.G.3    Kadouche, J.4    Roseto, A.5
  • 121
    • 77649122698 scopus 로고    scopus 로고
    • Generation of tumor-specific T lymphocytes using dendritic cell/tumor fusions and anti-CD3/CD28
    • Rosenblatt J, Wu Z, Vasir B, Zarwan C, Stone R, Mills H, et al. Generation of tumor-specific T lymphocytes using dendritic cell/tumor fusions and anti-CD3/CD28. J Immunother. 2010;33:155-66.
    • (2010) J Immunother , vol.33 , pp. 155-166
    • Rosenblatt, J.1    Wu, Z.2    Vasir, B.3    Zarwan, C.4    Stone, R.5    Mills, H.6
  • 122
    • 0041911491 scopus 로고    scopus 로고
    • Intratumoral expression of a fusogenic membrane glycoprotein enhances the efficacy of replicating adenovirus therapy
    • Ahmed A, Jevremovic D, Suzuki K, Kottke T, Thompson J, Emery S, et al. Intratumoral expression of a fusogenic membrane glycoprotein enhances the efficacy of replicating adenovirus therapy. Gene Ther. 2003;10:1663-71.
    • (2003) Gene Ther , vol.10 , pp. 1663-1671
    • Ahmed, A.1    Jevremovic, D.2    Suzuki, K.3    Kottke, T.4    Thompson, J.5    Emery, S.6
  • 123
    • 0034653696 scopus 로고    scopus 로고
    • Fusogenic membrane glycoproteins as a novel class of genes for the local and immune-mediated control of tumor growth
    • Bateman A, Bullough F, Murphy S, Emiliusen L, Lavillette D, Cosset FL, et al. Fusogenic membrane glycoproteins as a novel class of genes for the local and immune-mediated control of tumor growth. Cancer Res. 2000;60:1492-7.
    • (2000) Cancer Res , vol.60 , pp. 1492-1497
    • Bateman, A.1    Bullough, F.2    Murphy, S.3    Emiliusen, L.4    Lavillette, D.5    Cosset, F.L.6
  • 124
    • 0037112528 scopus 로고    scopus 로고
    • Viral fusogenic membrane glycoproteins kill solid tumor cells by nonapoptotic mechanisms that promote cross presentation of tumor antigens by dendritic cells
    • Bateman AR, Harrington KJ, Kottke T, Ahmed A, Melcher AA, Gough MJ, et al. Viral fusogenic membrane glycoproteins kill solid tumor cells by nonapoptotic mechanisms that promote cross presentation of tumor antigens by dendritic cells. Cancer Res. 2002;62:6566-78.
    • (2002) Cancer Res , vol.62 , pp. 6566-6578
    • Bateman, A.R.1    Harrington, K.J.2    Kottke, T.3    Ahmed, A.4    Melcher, A.A.5    Gough, M.J.6
  • 125
    • 0033759150 scopus 로고    scopus 로고
    • A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy
    • Diaz RM, Bateman A, Emiliusen L, Fielding A, Trono D, Russell SJ, et al. A lentiviral vector expressing a fusogenic glycoprotein for cancer gene therapy. Gene Ther. 2000;7: 1656-63.
    • (2000) Gene Ther , vol.7 , pp. 1656-1663
    • Diaz, R.M.1    Bateman, A.2    Emiliusen, L.3    Fielding, A.4    Trono, D.5    Russell, S.J.6
  • 126
    • 33644755625 scopus 로고    scopus 로고
    • Allogeneic tumor cells expressing fusogenic membrane glycoproteins as a platform for clinical cancer immunotherapy
    • Errington F, Bateman A, Kottke T, Thompson J, Harrington K, Merrick A, et al. Allogeneic tumor cells expressing fusogenic membrane glycoproteins as a platform for clinical cancer immunotherapy. Clin Cancer Res. 2006;12:1333-41.
    • (2006) Clin Cancer Res , vol.12 , pp. 1333-1341
    • Errington, F.1    Bateman, A.2    Kottke, T.3    Thompson, J.4    Harrington, K.5    Merrick, A.6
  • 127
    • 29944433608 scopus 로고    scopus 로고
    • Fusogenic membrane glycoprotein-mediated tumour cell fusion activates human dendritic cells for enhanced IL-12 production and T-cell priming
    • Errington F, Jones J, Merrick A, Bateman A, Harrington K, Gough M, et al. Fusogenic membrane glycoprotein-mediated tumour cell fusion activates human dendritic cells for enhanced IL-12 production and T-cell priming. Gene Ther. 2006;13:138-49.
    • (2006) Gene Ther , vol.13 , pp. 138-149
    • Errington, F.1    Jones, J.2    Merrick, A.3    Bateman, A.4    Harrington, K.5    Gough, M.6
  • 129
    • 0033692809 scopus 로고    scopus 로고
    • Viral fusogenic membrane glycoprotein expression causes syncytia formation with bioenergetic cell death: Implications for gene therapy
    • Higuchi H, Bronk SF, Bateman A, Harrington K, Vile RG, Gores GJ. Viral fusogenic membrane glycoprotein expression causes syncytia formation with bioenergetic cell death: Implications for gene therapy. Cancer Res. 2000;60:6396-402.
    • (2000) Cancer Res , vol.60 , pp. 6396-6402
    • Higuchi, H.1    Bronk, S.F.2    Bateman, A.3    Harrington, K.4    Vile, R.G.5    Gores, G.J.6
  • 130
    • 33747424377 scopus 로고    scopus 로고
    • Apoptotic, necrotic, or fused tumor cells: An equivalent source of antigen for dendritic cell loading
    • Larmonier N, Merino D, Nicolas A, Cathelin D, Besson A, Bateman A, et al. Apoptotic, necrotic, or fused tumor cells: An equivalent source of antigen for dendritic cell loading. Apoptosis. 2006;11:1513-24.
    • (2006) Apoptosis , vol.11 , pp. 1513-1524
    • Larmonier, N.1    Merino, D.2    Nicolas, A.3    Cathelin, D.4    Besson, A.5    Bateman, A.6
  • 131
    • 0036791104 scopus 로고    scopus 로고
    • Enhancing the efficacy of a weak allogeneic melanoma vaccine by viral fusogenic membrane glycoprotein- mediated tumor cell-tumor cell fusion
    • Linardakis E, Bateman A, Phan V, Ahmed A, Gough M, Olivier K, et al. Enhancing the efficacy of a weak allogeneic melanoma vaccine by viral fusogenic membrane glycoprotein- mediated tumor cell-tumor cell fusion. Cancer Res. 2002;62:5495-504.
    • (2002) Cancer Res , vol.62 , pp. 5495-5504
    • Linardakis, E.1    Bateman, A.2    Phan, V.3    Ahmed, A.4    Gough, M.5    Olivier, K.6
  • 132
    • 13644257013 scopus 로고    scopus 로고
    • Gene therapy for malignant glioma using Sindbis vectors expressing a fusogenic membrane glycoprotein
    • Zhang J, Frolov I, Russell SJ. Gene therapy for malignant glioma using Sindbis vectors expressing a fusogenic membrane glycoprotein. J Gene Med. 2004;6:1082-91.
    • (2004) J Gene Med , vol.6 , pp. 1082-1091
    • Zhang, J.1    Frolov, I.2    Russell, S.J.3
  • 133
    • 0141461410 scopus 로고    scopus 로고
    • A new genetic method to generate and isolate small, short-lived but highly potent dendritic cell-tumor cell hybrid vaccines
    • Phan V, Errington F, Cheong SC, Kottke T, Gough M, Altmann S, et al. A new genetic method to generate and isolate small, short-lived but highly potent dendritic cell-tumor cell hybrid vaccines. Nat Med. 2003;9:1215-9.
    • (2003) Nat Med , vol.9 , pp. 1215-1219
    • Phan, V.1    Errington, F.2    Cheong, S.C.3    Kottke, T.4    Gough, M.5    Altmann, S.6
  • 136
    • 77953615403 scopus 로고    scopus 로고
    • Polarized dendritic cells as cancer vaccines: Directing effector-type T cells to tumors
    • Kalinski P, Okada H. Polarized dendritic cells as cancer vaccines: Directing effector-type T cells to tumors. Sem Immunol.22:173-82.
    • Sem Immunol.22 , pp. 173-182
    • Kalinski, P.1    Okada, H.2
  • 137
    • 33746046073 scopus 로고    scopus 로고
    • IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells
    • Rosenberg SA, Sportes C, Ahmadzadeh M, Fry TJ, Ngo LT, Schwarz SL, et al. IL-7 administration to humans leads to expansion of CD8+ and CD4+ cells but a relative decrease of CD4+ T-regulatory cells. J Immunother. 2006;29:313-9.
    • (2006) J Immunother , vol.29 , pp. 313-319
    • Rosenberg, S.A.1    Sportes, C.2    Ahmadzadeh, M.3    Fry, T.J.4    Ngo, L.T.5    Schwarz, S.L.6
  • 138
    • 33947188082 scopus 로고    scopus 로고
    • Generation and functional assessment of antigen-specific T cells stimulated by fusions of dendritic cells and allogeneic breast cancer cells
    • Koido S, Tanaka Y, Tajiri H, Gong J. Generation and functional assessment of antigen-specific T cells stimulated by fusions of dendritic cells and allogeneic breast cancer cells. Vaccine. 2007;25:2610-9.
    • (2007) Vaccine , vol.25 , pp. 2610-2619
    • Koido, S.1    Tanaka, Y.2    Tajiri, H.3    Gong, J.4
  • 139
    • 35349015690 scopus 로고    scopus 로고
    • Dendritic cells fused with allogeneic breast cancer cell line induce tumor antigen-specific CTL responses against autologous breast cancer cells
    • Nov
    • Zhang Y, Ma B, Zhou Y, Zhang M, Qiu X, Sui Y, et al. Dendritic cells fused with allogeneic breast cancer cell line induce tumor antigen-specific CTL responses against autologous breast cancer cells. Breast Cancer Res Treat. 2007 Nov; 105(3):277-86.
    • (2007) Breast Cancer Res Treat , vol.105 , Issue.3 , pp. 277-286
    • Zhang, Y.1    Ma, B.2    Zhou, Y.3    Zhang, M.4    Qiu, X.5    Sui, Y.6
  • 140
    • 11244313924 scopus 로고    scopus 로고
    • Dendritic cells derived from metastatic cancer patients vaccinated with allogeneic dendritic cell-autologous tumor cell hybrids express more CD86 and induce higher levels of interferon-gamma in mixed lymphocyte reactions
    • Jan
    • Neves AR, Ensina LF, Anselmo LB, Leite KR, Buzaid AC, Camara-Lopes LH, et al. Dendritic cells derived from metastatic cancer patients vaccinated with allogeneic dendritic cell-autologous tumor cell hybrids express more CD86 and induce higher levels of interferon-gamma in mixed lymphocyte reactions. Cancer Immunol Immunother. 2005 Jan;54(1):61-6.
    • (2005) Cancer Immunol Immunother , vol.54 , Issue.1 , pp. 61-66
    • Neves, A.R.1    Ensina, L.F.2    Anselmo, L.B.3    Leite, K.R.4    Buzaid, A.C.5    Camara-Lopes, L.H.6
  • 141
    • 0037883616 scopus 로고    scopus 로고
    • Hybrids of dendritic cells and tumor cells generated by electrofusion simultaneously present immunodominant epitopes from multiple human tumor-associated antigens in the context of MHC class I and class II molecules
    • Parkhurst MR, DePan C, Riley JP, Rosenberg SA, Shu S. Hybrids of dendritic cells and tumor cells generated by electrofusion simultaneously present immunodominant epitopes from multiple human tumor-associated antigens in the context of MHC class I and class II molecules. J Immunol. 2003;170:5317-25.
    • (2003) J Immunol , vol.170 , pp. 5317-5325
    • Parkhurst, M.R.1    DePan, C.2    Riley, J.P.3    Rosenberg, S.A.4    Shu, S.5
  • 142
    • 2442422156 scopus 로고    scopus 로고
    • Tumour cell/dendritic cell fusions as a vaccination strategy for multiple myeloma
    • Raje N, Hideshima T, Davies FE, Chauhan D, Treon SP, Young G, et al. Tumour cell/dendritic cell fusions as a vaccination strategy for multiple myeloma. Br J Haematol. 2004;125:343-52.
    • (2004) Br J Haematol , vol.125 , pp. 343-352
    • Raje, N.1    Hideshima, T.2    Davies, F.E.3    Chauhan, D.4    Treon, S.P.5    Young, G.6
  • 143
    • 0034889876 scopus 로고    scopus 로고
    • Ex vivo generation of human anti-melanoma autologous cytolytic T cells by dendritic cell/melanoma cell hybridomas
    • Soruri A, Fayyazi A, Neumann C, Schlott T, Jung T, Matthes C, et al. Ex vivo generation of human anti-melanoma autologous cytolytic T cells by dendritic cell/melanoma cell hybridomas. Cancer Immunol Immunother. 2001;50:307-14.
    • (2001) Cancer Immunol Immunother , vol.50 , pp. 307-314
    • Soruri, A.1    Fayyazi, A.2    Neumann, C.3    Schlott, T.4    Jung, T.5    Matthes, C.6
  • 144
    • 20444495703 scopus 로고    scopus 로고
    • Fusion of dendritic cells with multiple myeloma cells results in maturation and enhanced antigen presentation
    • Vasir B, Borges V, Wu Z, Grosman D, Rosenblatt J, Irie M, et al. Fusion of dendritic cells with multiple myeloma cells results in maturation and enhanced antigen presentation. Br J Haematol. 2005;129:687-700.
    • (2005) Br J Haematol , vol.129 , pp. 687-700
    • Vasir, B.1    Borges, V.2    Wu, Z.3    Grosman, D.4    Rosenblatt, J.5    Irie, M.6
  • 145
    • 0037008855 scopus 로고    scopus 로고
    • Dendritomas formed by fusion of mature dendritic cells with allogenic human hepatocellular carcinoma cells activate autologous cytotoxic T lymphocytes
    • Chan RC, Xie H, Zhao GP, Xie Y. Dendritomas formed by fusion of mature dendritic cells with allogenic human hepatocellular carcinoma cells activate autologous cytotoxic T lymphocytes. Immunol Lett. 2002;83:101-9.
    • (2002) Immunol Lett , vol.83 , pp. 101-109
    • Chan, R.C.1    Xie, H.2    Zhao, G.P.3    Xie, Y.4
  • 146
    • 0042062585 scopus 로고    scopus 로고
    • Human autologous dendritic cell-glioma fusions: Feasibility and capacity to stimulate T cells with proliferative and cytolytic activity
    • Sloan AE, Parajuli P. Human autologous dendritic cell-glioma fusions: Feasibility and capacity to stimulate T cells with proliferative and cytolytic activity. J Neurooncol. 2003;64: 177-83.
    • (2003) J Neurooncol , vol.64 , pp. 177-183
    • Sloan, A.E.1    Parajuli, P.2
  • 147
    • 27744491292 scopus 로고    scopus 로고
    • Dendritic cells fused with allogeneic colorectal cancer cell line present multiple colorectal cancer-specific antigens and induce antitumor immunity against autologous tumor cells
    • Koido S, Hara E, Homma S, Torii A, Toyama Y, Kawahara H, et al. Dendritic cells fused with allogeneic colorectal cancer cell line present multiple colorectal cancer-specific antigens and induce antitumor immunity against autologous tumor cells. Clin Cancer Res. 2005;11:7891-900.
    • (2005) Clin Cancer Res , vol.11 , pp. 7891-7900
    • Koido, S.1    Hara, E.2    Homma, S.3    Torii, A.4    Toyama, Y.5    Kawahara, H.6
  • 148
    • 27144451051 scopus 로고    scopus 로고
    • Induction of antigen-specific CD4- and CD8-mediated T-cell responses by fusions of autologous dendritic cells and metastatic colorectal cancer cells
    • Nov 20
    • Koido S, Hara E, Torii A, Homma S, Toyama Y, Kawahara H, et al. Induction of antigen-specific CD4- and CD8-mediated T-cell responses by fusions of
    • (2005) Int J Cancer , vol.117 , Issue.4 , pp. 587-595
    • Koido, S.1    Hara, E.2    Torii, A.3    Homma, S.4    Toyama, Y.5    Kawahara, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.