메뉴 건너뛰기




Volumn 23, Issue 4, 2000, Pages 487-498

Phase 1 Study in Patients With Metastatic Melanoma of Immunization With Dendritic Cells Presenting Epitopes Derived From the Melanoma-Associated Antigens MART-1 and gp100

Author keywords

Anti tumor response; Intravenous administration; Melanoma antigen vaccination; Patient monitoring

Indexed keywords

MELANOMA ANTIGEN; MELANOMA VACCINE;

EID: 0033934224     PISSN: 15249557     EISSN: 15374513     Source Type: Journal    
DOI: 10.1097/00002371-200007000-00013     Document Type: Article
Times cited : (158)

References (39)
  • 1
    • 0011956359 scopus 로고    scopus 로고
    • Principles of tumor immunity: Biology of cellular immune responses. in: Devita vt, hellman s, rosenberg sa, eds. biologic therapy of cancer
    • Restifo NP, Wunderlich JR. Principles of tumor immunity: biology of cellular immune responses. In: DeVita VT, Hellman S, Rosenberg SA, eds. Biologic Therapy of Cancer. Philadelphia: JB Lippincott, 1996, 3-21.
    • Philadelphia: JB Lippincott , vol.1996 , pp. 3-21
    • Restifo, N.P.1    Wunderlich, J.R.2
  • 2
    • 0030890836 scopus 로고    scopus 로고
    • Cancer vaccines based on the identification of genes encoding cancer regression antigens
    • Rosenberg SA. Cancer vaccines based on the identification of genes encoding cancer regression antigens. Immunol Today 1997; 18:175-82.
    • (1997) Immunol Today , vol.18 , pp. 175
    • Rosenberg, S.A.1
  • 4
    • 0028302028 scopus 로고
    • Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes
    • Kawakami Y, Eliyahu S, Sakaguchi K, et al. Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes. J Exp Med 1994; 180:347-52.
    • (1994) J Exp Med , vol.180 , pp. 347
    • Kawakami, Y.1    Eliyahu, S.2    Sakaguchi, K.3
  • 5
    • 0028303166 scopus 로고
    • A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas [see comments]
    • Coulie PG, Brichard V, Van Pel A, et al. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas [see comments]. J Exp Med 1994; 180:35-42.
    • (1994) J Exp Med , vol.180 , pp. 35
    • Coulie, P.G.1    Brichard, V.2    Van Pel, A.3
  • 6
    • 14844341146 scopus 로고
    • Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression
    • Kawakami Y, Eliyahu S, Jennings C, et al. Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression. J Immunol 1995; 154:3961-8.
    • (1995) J Immunol , vol.154 , pp. 3961
    • Kawakami, Y.1    Eliyahu, S.2    Jennings, C.3
  • 7
    • 0028316911 scopus 로고
    • Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor
    • Kawakami Y, Eliyahu S, Delgado CH, et al. Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor. Proc Natl Acad Sci USA 1994; 91:3515-3519.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3515
    • Kawakami, Y.1    Eliyahu, S.2    Delgado, C.H.3
  • 8
    • 0028298174 scopus 로고
    • Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection
    • Kawakami Y, Eliyahu S, Delgado CH, et al. Identification of a human melanoma antigen recognized by tumor-infiltrating lymphocytes associated with in vivo tumor rejection. Proc Natl Acad Sci USA 1994; 91:6458-62.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6458
    • Kawakami, Y.1    Eliyahu, S.2    Delgado, C.H.3
  • 9
    • 0032528404 scopus 로고    scopus 로고
    • Stringent allele/epitope requirements for MART-1/Melan A immunodominance: implications for peptide-based immunotherapy
    • Bettinotti M, Kim CJ, Lee K-H, et al. Stringent allele/epitope requirements for MART-1/Melan A immunodominance: implications for peptide-based immunotherapy. J Immunol 1998; 161:877-89.
    • (1998) J Immunol , vol.161 , pp. 877
    • Bettinotti, M.1    Kim, C.J.2    Lee, K.-H.3
  • 10
    • 0031983670 scopus 로고    scopus 로고
    • Immunodominance across the HLA polymorphism: implications for cancer immunotherapy
    • Kim CJ, Parkinson DR, Marincola FM. Immunodominance across the HLA polymorphism: implications for cancer immunotherapy. J Immunother 1997; 21:1-16.
    • (1997) J Immunother , vol.21 , pp. 1
    • Kim, C.J.1    Parkinson, D.R.2    Marincola, F.M.3
  • 11
    • 0028871599 scopus 로고
    • Recognition of multiple epitopes in the human melanoma antigen gp 100 by peripheral blood lymphocytes stimulated in vitro with synthetic peptides
    • Salgaller ML, Afshar A, Marincola FM, et al. Recognition of multiple epitopes in the human melanoma antigen gp 100 by peripheral blood lymphocytes stimulated in vitro with synthetic peptides. Cancer Res 1995; 55:4972-9.
    • (1995) Cancer Res , vol.55 , pp. 4972
    • Salgaller, M.L.1    Afshar, A.2    Marincola, F.M.3
  • 12
    • 0028942142 scopus 로고
    • Induction of tumor reactive CTL from peripheral blood and tumor infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1
    • Rivoltini L, Kawakami Y, Sakaguchi K, et al. Induction of tumor reactive CTL from peripheral blood and tumor infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1. J Immunol 1995; 154:2257-65.
    • (1995) J Immunol , vol.154 , pp. 2257
    • Rivoltini, L.1    Kawakami, Y.2    Sakaguchi, K.3
  • 13
    • 0030587077 scopus 로고    scopus 로고
    • Improved induction of melanoma reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201 binding residues
    • Parkhurst MR, Salgaller ML, Southwood S, et al. Improved induction of melanoma reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201 binding residues. J Immunol 1996; 157:2539-48.
    • (1996) J Immunol , vol.157 , pp. 2539
    • Parkhurst, M.R.1    Salgaller, M.L.2    Southwood, S.3
  • 14
    • 0030996710 scopus 로고    scopus 로고
    • Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A [see comments]
    • Cormier JN, Salgaller ML, Prevette T, et al. Enhancement of cellular immunity in melanoma patients immunized with a peptide from MART-1/Melan A [see comments]. Cancer J Sci Am 1997; 3:37-44.
    • (1997) Cancer J Sci Am , vol.3 , pp. 37
    • Cormier, J.N.1    Salgaller, M.L.2    Prevette, T.3
  • 15
    • 0029837404 scopus 로고    scopus 로고
    • Immunization against epitopes in the human melanoma antigen gp100 following patient immunization with synthetic peptides
    • Salgaller ML, Marincola FM, Cormier JN, Rosenberg SA. Immunization against epitopes in the human melanoma antigen gp100 following patient immunization with synthetic peptides. Cancer Res 1996; 56:4749-57.
    • (1996) Cancer Res , vol.56 , pp. 4749
    • Salgaller, M.L.1    Marincola, F.M.2    Cormier, J.N.3    Rosenberg, S.A.4
  • 16
    • 0028876917 scopus 로고
    • Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans
    • Vitiello A, Ishioka G, Grey HM, et al. Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans. J Clin Invest 1995; 95:341-9.
    • (1995) J Clin Invest , vol.95 , pp. 341
    • Vitiello, A.1    Ishioka, G.2    Grey, H.M.3
  • 17
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman RM. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 1991; 9:271-96.
    • (1991) Annu Rev Immunol , vol.9 , pp. 271
    • Steinman, R.M.1
  • 18
    • 0030070340 scopus 로고    scopus 로고
    • Dendritic cells as adjuvants for class I major histocompatibility complex-restricted antitumor immunity [comment]
    • Young JW, Inaba K. Dendritic cells as adjuvants for class I major histocompatibility complex-restricted antitumor immunity [comment]. J Exp Med 1996; 183:7-11.
    • (1996) J Exp Med , vol.183 , pp. 7
    • Young, J.W.1    Inaba, K.2
  • 19
    • 0028793675 scopus 로고
    • Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity
    • Mayordomo JI, Zorina T, Storkus WJ, et al. Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic antitumour immunity. Nat Med 1995; 1:1297-1302.
    • (1995) Nat Med , vol.1 , pp. 1297
    • Mayordomo, J.I.1    Zorina, T.2    Storkus, W.J.3
  • 20
    • 0030028770 scopus 로고    scopus 로고
    • Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo [see comments]
    • Paglia P, Chiodoni C, Rodolfo M, Colombo MP. Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo [see comments]. J Exp Med 1996; 183:317-22.
    • (1996) J Exp Med , vol.183 , pp. 317
    • Paglia, P.1    Chiodoni, C.2    Rodolfo, M.3    Colombo, M.P.4
  • 21
    • 0030048724 scopus 로고    scopus 로고
    • Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity [see comments]
    • Celluzzi CM, Mayordomo JI, Storkus WJ, Lotze MT, Falo Jr. LD Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity [see comments]. J Exp Med 1996; 183:283-87.
    • (1996) J Exp Med , vol.183 , pp. 283
    • Celluzzi, C.M.1    Mayordomo, J.I.2    Storkus, W.J.3    Lotze, M.T.4    Falo, L.D.5
  • 22
    • 0030058647 scopus 로고    scopus 로고
    • Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines [see comments]
    • Zitvogel L, Mayordomo JI, Tjandrawan T, et al. Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines [see comments]. J Exp Med 1996; 183:87-97.
    • (1996) J Exp Med , vol.183 , pp. 87
    • Zitvogel, L.1    Mayordomo, J.I.2    Tjandrawan, T.3
  • 23
    • 0028289244 scopus 로고
    • Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
    • Sallusto F, Lanzavecchia A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J Exp Med 1994; 179:1109-18.
    • (1994) J Exp Med , vol.179 , pp. 1109
    • Sallusto, F.1    Lanzavecchia, A.2
  • 24
    • 0028285230 scopus 로고
    • Proliferating dendritic cell progenitors in human blood
    • Romani N, Gruner S, Brang D, et al. Proliferating dendritic cell progenitors in human blood. J Exp Med 1994; 180:83-93.
    • (1994) J Exp Med , vol.180 , pp. 83
    • Romani, N.1    Gruner, S.2    Brang, D.3
  • 25
    • 0031464143 scopus 로고    scopus 로고
    • Dendritic cells infected with poxviruses encoding MART-1/MelanA sensitize T lymphocytes in vitro
    • Kim CJ, Prevette T, Cormier JN, et al. Dendritic cells infected with poxviruses encoding MART-1/MelanA sensitize T lymphocytes in vitro. J Immunother 1997; 20:276-86.
    • (1997) J Immunother , vol.20 , pp. 276
    • Kim, C.J.1    Prevette, T.2    Cormier, J.N.3
  • 26
    • 0030026776 scopus 로고    scopus 로고
    • Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells
    • Hsu FJ, Benike C, Fagnoni F, et al. Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nat Med 1996; 2:52-8.
    • (1996) Nat Med , vol.2 , pp. 52
    • Hsu, F.J.1    Benike, C.2    Fagnoni, F.3
  • 27
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide-or tumor lysate-pulsed dendritic cells
    • Nestle FO, Alijagic S, Gilliet M, et al. Vaccination of melanoma patients with peptide-or tumor lysate-pulsed dendritic cells. Nat Med 1998; 4:328-32.
    • (1998) Nat Med , vol.4 , pp. 328
    • Nestle, F.O.1    Alijagic, S.2    Gilliet, M.3
  • 28
    • 10544242201 scopus 로고    scopus 로고
    • Differences in frequency distribution of HLA-A2 subtypes between North American and Italian white melanoma patients: relevance for epitope specific vaccination protocols
    • Player MA, Barracchini KC, Simonis TB, et al. Differences in frequency distribution of HLA-A2 subtypes between North American and Italian white melanoma patients: relevance for epitope specific vaccination protocols. J Immunother 1996; 19:357-63.
    • (1996) J Immunother , vol.19 , pp. 357
    • Player, M.A.1    Barracchini, K.C.2    Simonis, T.B.3
  • 29
    • 0026576422 scopus 로고
    • HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides [see comments]
    • Wei ML, Cresswell P. HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides [see comments]. Nature 1992; 356:443-6.
    • (1992) Nature , vol.356 , pp. 443
    • Wei, M.L.1    Cresswell, P.2
  • 30
    • 0020042925 scopus 로고
    • Monomorphic anti-HLA-A, B, C monoclonal antibodies detecting molecular subunits and combinatorial determinants
    • Brodsky FM, Parham P. Monomorphic anti-HLA-A, B, C monoclonal antibodies detecting molecular subunits and combinatorial determinants. J Immunol 1982; 128:129-35.
    • (1982) J Immunol , vol.128 , pp. 129
    • Brodsky, F.M.1    Parham, P.2
  • 31
    • 0023832325 scopus 로고
    • Fine specificity and idiotype diversity of the murine anti-HLA-A2, A28 monoclonal antibodies CR11-351 and KS1
    • Tsujisaki M, Sakaguchi K, Igarashi M, et al. Fine specificity and idiotype diversity of the murine anti-HLA-A2, A28 monoclonal antibodies CR11-351 and KS1. Transplantation 1988; 45:632-9.
    • (1988) Transplantation , vol.45 , pp. 632
    • Tsujisaki, M.1    Sakaguchi, K.2    Igarashi, M.3
  • 32
    • 1842335724 scopus 로고    scopus 로고
    • A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing
    • Cella M, Dohring C, Samaridis J, et al. A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J Exp Med 1997; 185:1743-51.
    • (1997) J Exp Med , vol.185 , pp. 1743
    • Cella, M.1    Dohring, C.2    Samaridis, J.3
  • 33
    • 0032928064 scopus 로고    scopus 로고
    • Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in an in vitro melanoma model
    • Cormier JN, Panelli MC, Hackett JA, et al. Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in an in vitro melanoma model. Int J Cancer 1999; 80:781-90.
    • (1999) Int J Cancer , vol.80 , pp. 781
    • Cormier, J.N.1    Panelli, M.C.2    Hackett, J.A.3
  • 34
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic tumor associated peptide vaccine for the treatment of patients with metastatic melanoma
    • Rosenberg SA, Yang JC, Schwartzentruber D, et al. Immunologic and therapeutic evaluation of a synthetic tumor associated peptide vaccine for the treatment of patients with metastatic melanoma. Nat Med 1998; 4:321-7.
    • (1998) Nat Med , vol.4 , pp. 321
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.3
  • 35
    • 0028181372 scopus 로고
    • Localization of 111indium-labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with response
    • Pockaj BA, Sherry RM, Wei JP, et al. Localization of 111indium-labeled tumor infiltrating lymphocytes to tumor in patients receiving adoptive immunotherapy. Augmentation with cyclophosphamide and correlation with response. Cancer 1994; 73:1731-7.
    • (1994) Cancer , vol.73 , pp. 1731
    • Pockaj, B.A.1    Sherry, R.M.2    Wei, J.P.3
  • 36
    • 0031819362 scopus 로고    scopus 로고
    • Use of recombinant poxviruses to stimulate anti-melanoma T cell reactivity
    • Kim CJ, Cormier JN, Roden M, et al. Use of recombinant poxviruses to stimulate anti-melanoma T cell reactivity. Ann Surg Oncol 1998; 5:64-76.
    • (1998) Ann Surg Oncol , vol.5 , pp. 64
    • Kim, C.J.1    Cormier, J.N.2    Roden, M.3
  • 37
    • 0032482337 scopus 로고    scopus 로고
    • A conditioned dendritic cell can be a temporal bridge between a CD4-T-helper and a T-killer cell [see comments]
    • Ridge JP, Di Rosa F, Matzinger P. A conditioned dendritic cell can be a temporal bridge between a CD4-T-helper and a T-killer cell [see comments]. Nature 1998; 393:474-8.
    • (1998) Nature , vol.393 , pp. 474
    • Ridge, J.P.1    Di Rosa, F.2    Matzinger, P.3
  • 38
    • 0029812593 scopus 로고    scopus 로고
    • Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation
    • Cella M, Scheidegger D, Palmer-Lehmann K, et al. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med 1996; 184:747-52.
    • (1996) J Exp Med , vol.184 , pp. 747
    • Cella, M.1    Scheidegger, D.2    Palmer-Lehmann, K.3
  • 39
    • 0031045622 scopus 로고    scopus 로고
    • Origin, maturation and antigen presenting function of dendritic cells
    • Cella M, Sallusto F, Lanzavecchia A. Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol 1997; 9:10-16.
    • (1997) Curr Opin Immunol , vol.9 , pp. 10
    • Cella, M.1    Sallusto, F.2    Lanzavecchia, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.