Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression - A role in the immune tolerance to antigenic tumors

Advances in Experimental Medicine and Biology

Volumn 417, Issue , 1997, Pages 525-528

  Chaux, Pascal ^a   Favre, Nathalie ^a   Bonnotte, Bernard ^a   Moutet, Monique ^a   Martin, Monique ^a   Martin, François ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; CLONAL ANERGY; COLORECTAL CANCER; CONFERENCE PAPER; DENDRITIC CELL; HUMAN; HUMAN TISSUE; IMMUNOLOGICAL TOLERANCE; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD80; ANTIGENS, NEOPLASM; COLORECTAL NEOPLASMS; DENDRITIC CELLS; HUMANS; IMMUNE TOLERANCE; LYMPHOCYTES, TUMOR-INFILTRATING; NEOPLASMS; PHENOTYPE; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0030766236     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4757-9966-8_86     Document Type: Article

References (11)

1. Boon, T., Cerottini, J.C., Van Den Eynde, B., Van Der Bruggen, P. and Van Pel, A., Tumor rejection antigens recognized by T lymphocytes. Annu. Rev. Immunol., 12, 337-365 (1994).
2. Caignard, A., Martin, M.S., Michel, M.F. and Martin, F., Interaction between two cellular subpopulations of a rat colonie carcinoma when inoculated to the syngeneic host. Int. J. Cancer, 36, 273-279 (1985).
3. Caignard, A., Pelletier, H. and Martin, F., Specificity of the immune response leading to protection or enhancement by regressive and progressive variants of a rat colon carcinoma. Int. J. Cancer, 42, 883-886(1988).
4. Chaux, P., Hammann, A., Martin, F. and Martin, M., Surface phenotype and functions of tumor-infiltrating dendritic cells: CD8 expression by a cell subpopulation. Eur. J. Immunol., 23, 2517-2525 (1993).
5. Caux C., Massacrier, C., Vanbervliet, B., Dubois, B., Van Kooten, C., Durand, I. and Banchereau, J., Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med., 180, 1263-1272 (1994).
6. Schwartz, R.H., Costimulation of T lymphocytes: the role of CD28, CTLA4, and B7/BB1 in interleukin-2 production and immunotherapy. Cell, 71, 1065-1068 (1992).
7. Gimmi, C.D., Freeman, G.J., Gribben, J.G., Gray, G. and Nadler, L.M., Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation. Proc. Natl. Acad. Sci. (USA), 90, 6586-6590 (1993).
8. Harding, F.A., McArthur, J.G., Gross, J.A., Raulet, D.H. and Allison, J.P., CD28-mediated signalling costimulates murine T cells and prevents induction of anergy in T cell clones. Nature, 356, 607-609 (1992).
9. Chaux, P., Moutet, M., Faivre, J., Martin, F. and Martin, M. Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of the T cell activation. Lab. Invest. 74, 975-983 (1996).
10. Linsley, P.S., Brady, W., Urnes, M., Grosmaire, L.S., Damle, N.K. and Ledbetter, J.A., CTLA4 is a second receptor for the B cell activation antigen B7. J. Exp. Med., 174, 561-569 (1991).
11. Chaux, P., Martin, M.S. and Martin, F. T-cell costimulation by the CD28 ligand B7 is involved in the immune response leading to rejection of a spontaneously regressive tumor. Int. J. Cancer 66, 244-248 (1996).