Saturation of transgene protein synthesis from mRNA in cells producing a large number of transgene mRNA

Biotechnology and Bioengineering

Volumn 108, Issue 10, 2011, Pages 2380-2389

  Takahashi, Yuki ^a   Nishikawa, Makiya ^a   Takiguchi, Naomi ^a   Suehara, Tetsuya ^a   Takakura, Yoshinobu ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

MRNA expression; Plasmid vector; RNA interference; Saturation; Transgene expression

Indexed keywords

CATIONIC LIPOSOMES; ENDOGENOUS GENES; FIREFLY LUCIFERASE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE; HYDRODYNAMIC INJECTION; MOUSE LIVER; MRNA EXPRESSION; PLASMID VECTOR; PLASMID VECTORS; PROTEIN EXPRESSION LEVELS; PROTEIN SYNTHESIS; RENILLA LUCIFERASE; RNA INTERFERENCE; SATURATION KINETICS; TRANSGENE; TRANSGENE EXPRESSION;

BIOSYNTHESIS; DNA; LIPOSOMES; MAMMALS; PHOSPHOLIPIDS; PROTEINS; RNA;

GENE EXPRESSION;

FIREFLY LUCIFERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; LIPOSOME; MESSENGER RNA; PLASMID VECTOR; RENILLA LUCIFERIN 2 MONOOXYGENASE; SMALL INTERFERING RNA; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSFECTION; HYDRODYNAMICS; IN VITRO STUDY; INJECTION; LIVER; MALE; MEDIATOR; MOUSE; NONHUMAN; PLASMID; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; REDUCTION; TRANSGENE; ANIMAL; BIOSYNTHESIS; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHARMACOLOGY; TUMOR CELL LINE;

RENILLA LUCIFERASE;

ANIMALS; CELL LINE, TUMOR; GENE TRANSFER TECHNIQUES; MICE; PLASMIDS; PROTEIN BIOSYNTHESIS; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSGENES;

EID: 80051786015     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23179     Document Type: Article

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