메뉴 건너뛰기




Volumn 84, Issue 2, 2011, Pages

Local elasticity of strained DNA studied by all-atom simulations

Author keywords

[No Author keywords available]

Indexed keywords

ALL-ATOM SIMULATIONS; BENDING RIGIDITY; BIOLOGICAL FUNCTIONS; BIOLOGICAL IMPLICATIONS; EXPERIMENTAL OBSERVATION; EXPERIMENTAL VALUES; FORCES AND TORQUES; GENOMIC DNA; LOCAL ELASTICITY; LOCAL MECHANICAL PROPERTIES; MECHANICAL STRESS; MOLECULAR DYNAMICS SIMULATIONS; TORSIONAL RIGIDITY;

EID: 80051651729     PISSN: 15393755     EISSN: 15502376     Source Type: Journal    
DOI: 10.1103/PhysRevE.84.021903     Document Type: Article
Times cited : (12)

References (96)
  • 3
    • 0030014783 scopus 로고    scopus 로고
    • ARBOAW 0066-4154 10.1146/annurev.bi.65.070196.003223
    • J. C. Wang, Annu. Rev. Biochem. ARBOAW 0066-4154 10.1146/annurev.bi.65. 070196.003223 65, 635 (1996).
    • (1996) Annu. Rev. Biochem. , vol.65 , pp. 635
    • Wang, J.C.1
  • 4
    • 0036085460 scopus 로고    scopus 로고
    • Cellular roles of DNA topoisomerases: A molecular perspective
    • DOI 10.1038/nrm831
    • J. C. Wang, Nat. Rev. Mol. Cell Biol. NRMCBP 1471-0072 10.1038/nrm831 3, 430 (2002). (Pubitemid 34685700)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.6 , pp. 430-440
    • Wang, J.C.1
  • 6
    • 13444288385 scopus 로고    scopus 로고
    • DNA supercoiling - A global transcriptional regulator for enterobacterial growth?
    • DOI 10.1038/nrmicro1088
    • A. Travers and G. Muskhelishvili, Nat. Rev. Microbiol. ABBSE4 1740-1526 10.1038/nrmicro1088 3, 157 (2005). (Pubitemid 40207596)
    • (2005) Nature Reviews Microbiology , vol.3 , Issue.2 , pp. 157-169
    • Travers, A.1    Muskhelishvili, G.2
  • 7
    • 0023162378 scopus 로고
    • All three elements of the lac p(s) promoter mediate its transcriptional response to DNA supercoiling
    • DOI 10.1016/0022-2836(87)90329-9
    • J. A. Borowiec and J. D. Gralla, J. Mol. Biol. JMOBAK 0022-2836 10.1016/0022-2836(87)90329-9 195, 89 (1987). (Pubitemid 17095647)
    • (1987) Journal of Molecular Biology , vol.195 , Issue.1 , pp. 89-97
    • Borowiec, J.A.1    Gralla, J.D.2
  • 12
    • 0028495164 scopus 로고
    • MAMOBX 0024-9297 10.1021/ma00098a016
    • A. V. Vologodskii, Macromolecules MAMOBX 0024-9297 10.1021/ma00098a016 27, 5623 (1994).
    • (1994) Macromolecules , vol.27 , pp. 5623
    • Vologodskii, A.V.1
  • 13
    • 0030973367 scopus 로고    scopus 로고
    • BIOJAU 0006-3495 10.1016/S0006-3495(97)78053-6
    • A. V. Vologodskii and J. F. Marko, Biophys. J. BIOJAU 0006-3495 10.1016/S0006-3495(97)78053-6 73, 123 (1997).
    • (1997) Biophys. J. , vol.73 , pp. 123
    • Vologodskii, A.V.1    Marko, J.F.2
  • 18
    • 0017427870 scopus 로고
    • CRBBEJ 1040-9238 10.3109/10409237709102561
    • R. D. Wells, CRC Crit. Rev. Biochem. CRBBEJ 1040-9238 10.3109/10409237709102561 4, 305 (1977).
    • (1977) CRC Crit. Rev. Biochem. , vol.4 , pp. 305
    • Wells, R.D.1
  • 19
    • 0017795493 scopus 로고
    • ABPBBK 0084-6589 10.1146/annurev.bb.07.060178.001443
    • W. R. Bauer, Annu. Rev. Biophys. Bioeng. ABPBBK 0084-6589 10.1146/annurev.bb.07.060178.001443 7, 287 (1978).
    • (1978) Annu. Rev. Biophys. Bioeng. , vol.7 , pp. 287
    • Bauer, W.R.1
  • 20
    • 0037008678 scopus 로고    scopus 로고
    • The bacterial histone-like protein HU specifically recognizes similar structures in all nucleic acids. DNA, RNA, and their hybrids
    • DOI 10.1074/jbc.M201978200
    • A. Balandina, D. Kamashev, and J. Rouviere-Yaniv, J. Biol. Chem. JBCHA3 0021-9258 10.1074/jbc.M201978200 277, 27622 (2002). (Pubitemid 34966704)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.31 , pp. 27622-27628
    • Balandina, A.1    Kamashev, D.2    Rouviere-Yaniv, J.3
  • 21
    • 0025363121 scopus 로고
    • JMOBAK 0022-2836 10.1016/S0022-2836(05)80272-4
    • T. C. Boles, J. H. White, and N. R. Cozzarelli, J. Mol. Biol. JMOBAK 0022-2836 10.1016/S0022-2836(05)80272-4 213, 931 (1990).
    • (1990) J. Mol. Biol. , vol.213 , pp. 931
    • Boles, T.C.1    White, J.H.2    Cozzarelli, N.R.3
  • 25
    • 33845351506 scopus 로고    scopus 로고
    • Torsional rigidities of weakly strained DNAs
    • DOI 10.1529/biophysj.106.087593
    • B. S. Fujimoto, G. P. Brewood, and J. M. Schurr, Biophys. J. BIOJAU 0006-3495 10.1529/biophysj.106.087593 91, 4166 (2006). (Pubitemid 44887275)
    • (2006) Biophysical Journal , vol.91 , Issue.11 , pp. 4166-4179
    • Fujimoto, B.S.1    Brewood, G.P.2    Schurr, J.M.3
  • 26
    • 33747461393 scopus 로고    scopus 로고
    • DNA overwinds when stretched
    • DOI 10.1038/nature04974, PII NATURE04974
    • J. Gore, Z. Bryant, M. Nollmann, M. U. Le, N. R. Cozzarelli, and C. Bustamante, Nature (London) NATUAS 0028-0836 10.1038/nature04974 442, 836 (2006). (Pubitemid 44258916)
    • (2006) Nature , vol.442 , Issue.7104 , pp. 836-839
    • Gore, J.1    Bryant, Z.2    Nollmann, M.3    Le, M.U.4    Cozzarelli, N.R.5    Bustamante, C.6
  • 28
    • 0025366778 scopus 로고
    • Dependence of the torsional rigidity of DNA on base composition
    • DOI 10.1038/344175a0
    • B. S. Fujimoto and J. M. Schurr, Nature (London) NATUAS 0028-0836 10.1038/344175a0 344, 175 (1990). (Pubitemid 20094139)
    • (1990) Nature , vol.344 , Issue.6262 , pp. 175-178
    • Fujimoto, B.S.1    Schurr, J.M.2
  • 30
    • 0023746243 scopus 로고
    • ABPBBK 0084-6589 10.1146/annurev.bb.17.060188.001405
    • P. J. Hagerman, Annu. Rev. Biophys. Biophys. Chem. ABPBBK 0084-6589 10.1146/annurev.bb.17.060188.001405 17, 265 (1988).
    • (1988) Annu. Rev. Biophys. Biophys. Chem. , vol.17 , pp. 265
    • Hagerman, P.J.1
  • 31
    • 0030024985 scopus 로고    scopus 로고
    • SCIEAS 0036-8075 10.1126/science.271.5250.795
    • S. B. Smith, Y. Cui, and C. Bustamante, Science SCIEAS 0036-8075 10.1126/science.271.5250.795 271, 795 (1996).
    • (1996) Science , vol.271 , pp. 795
    • Smith, S.B.1    Cui, Y.2    Bustamante, C.3
  • 36
    • 33846823909 scopus 로고
    • JCPSA6 0021-9606 10.1063/1.464397
    • T. Darden, D. York, and L. Pedersen, J. Chem. Phys. JCPSA6 0021-9606 10.1063/1.464397 98, 10089 (1993).
    • (1993) J. Chem. Phys. , vol.98 , pp. 10089
    • Darden, T.1    York, D.2    Pedersen, L.3
  • 38
    • 0033654654 scopus 로고    scopus 로고
    • ARPLAP 0066-426X 10.1146/annurev.physchem.51.1.435
    • T. E. CheathamIII and P. A. Kollman, Annu. Rev. Phys. Chem. ARPLAP 0066-426X 10.1146/annurev.physchem.51.1.435 51, 435 (2000).
    • (2000) Annu. Rev. Phys. Chem. , vol.51 , pp. 435
    • Cheathamiii, T.E.1    Kollman, P.A.2
  • 40
    • 33845381916 scopus 로고    scopus 로고
    • Evaluation of elastic properties of atomistic DNA models
    • DOI 10.1529/biophysj.106.091280
    • A. K. Mazur, Biophys. J. BIOJAU 0006-3495 10.1529/biophysj.106.091280 91, 4507 (2006). (Pubitemid 44904235)
    • (2006) Biophysical Journal , vol.91 , Issue.12 , pp. 4507-4518
    • Mazur, A.K.1
  • 41
    • 34547349079 scopus 로고    scopus 로고
    • Wormlike chain theory and bending of short DNA
    • DOI 10.1103/PhysRevLett.98.218102
    • A. K. Mazur, Phys. Rev. Lett. PRLTAO 0031-9007 10.1103/PhysRevLett.98. 218102 98, 218102 (2007). (Pubitemid 47139678)
    • (2007) Physical Review Letters , vol.98 , Issue.21 , pp. 218102
    • Mazur, A.K.1
  • 42
    • 45549083298 scopus 로고    scopus 로고
    • JPCBFK 1520-6106 10.1021/jp711815x
    • A. K. Mazur, J. Phys. Chem. B JPCBFK 1520-6106 10.1021/jp711815x 112, 4975 (2008).
    • (2008) J. Phys. Chem. B , vol.112 , pp. 4975
    • Mazur, A.K.1
  • 43
    • 65249143366 scopus 로고    scopus 로고
    • JPCBFK 1520-6106 10.1021/jp8098945
    • A. K. Mazur, J. Phys. Chem. B JPCBFK 1520-6106 10.1021/jp8098945 113, 2077 (2009).
    • (2009) J. Phys. Chem. B , vol.113 , pp. 2077
    • Mazur, A.K.1
  • 45
    • 0344327079 scopus 로고    scopus 로고
    • Structure, force, and energy of a double-stranded DNA oligonucleotide under tensile loads
    • DOI 10.1007/s002490050224
    • A. D. MacKerell Jr., and G. U. Lee, Eur. Biophys. J. EBJOE8 0175-7571 10.1007/s002490050224 28, 415 (1999). (Pubitemid 29287524)
    • (1999) European Biophysics Journal , vol.28 , Issue.5 , pp. 415-426
    • MacKerell Jr., A.D.1    Lee, G.U.2
  • 46
    • 21244498669 scopus 로고    scopus 로고
    • Molecular dynamics simulations of duplex stretching reveal the importance of entropy in determining the biomechanical properties of DNA
    • DOI 10.1529/biophysj.104.046912
    • S. A. Harris, Z. A. Sands, and C. A. Laughton, Biophys. J. BIOJAU 0006-3495 10.1529/biophysj.104.046912 88, 1684 (2005). (Pubitemid 40976185)
    • (2005) Biophysical Journal , vol.88 , Issue.3 , pp. 1684-1691
    • Harris, S.A.1    Sands, Z.A.2    Laughton, C.A.3
  • 47
    • 51749090178 scopus 로고    scopus 로고
    • PRLTAO 0031-9007 10.1103/PhysRevLett.101.118101
    • B. Luan and A. Aksimentiev, Phys. Rev. Lett. PRLTAO 0031-9007 10.1103/PhysRevLett.101.118101 101, 118101 (2008).
    • (2008) Phys. Rev. Lett. , vol.101 , pp. 118101
    • Luan, B.1    Aksimentiev, A.2
  • 48
    • 33749524793 scopus 로고    scopus 로고
    • B-DNA under stress: Over- and untwisting of DNA during molecular dynamics simulations
    • DOI 10.1529/biophysj.106.087163
    • S. Kannan, K. Kohlhoff, and M. Zacharias, Biophys. J. BIOJAU 0006-3495 10.1529/biophysj.106.087163 91, 2956 (2006). (Pubitemid 44526486)
    • (2006) Biophysical Journal , vol.91 , Issue.8 , pp. 2956-2965
    • Kannan, S.1    Kohlhoff, K.2    Zacharias, M.3
  • 51
    • 42449117606 scopus 로고    scopus 로고
    • Magnitude and direction of DNA bending induced by screw-axis orientation: Influence of sequence, mismatches and abasic sites
    • DOI 10.1093/nar/gkm1135
    • J. Curuksu, K. Zakrzewska, and M. Zacharias, Nucleic Acids Res. NARHAD 0305-1048 10.1093/nar/gkm1135 36, 2268 (2008). (Pubitemid 351567000)
    • (2008) Nucleic Acids Research , vol.36 , Issue.7 , pp. 2268-2283
    • Curuksu, J.1    Zakrzewska, K.2    Zacharias, M.3
  • 52
    • 73549083658 scopus 로고    scopus 로고
    • NARHAD 1549-9618 10.1021/ct900124n
    • A. K. Mazur, J. Chem. Theory Comput. NARHAD 1549-9618 10.1021/ct900124n 5, 2149 (2009).
    • (2009) J. Chem. Theory Comput. , vol.5 , pp. 2149
    • Mazur, A.K.1
  • 53
    • 77954136751 scopus 로고    scopus 로고
    • PRLTAO 0031-9007 10.1103/PhysRevLett.105.018102
    • A. K. Mazur, Phys. Rev. Lett. PRLTAO 0031-9007 10.1103/PhysRevLett.105. 018102 105, 018102 (2010).
    • (2010) Phys. Rev. Lett. , vol.105 , pp. 018102
    • Mazur, A.K.1
  • 60
    • 0032582494 scopus 로고    scopus 로고
    • Force and velocity measured for single molecules of RNA polymerase
    • DOI 10.1126/science.282.5390.902
    • M. D. Wang, M. J. Schnitzer, H. Yin, R. Landick, J. Gelles, and S. M. Block, Science SCIEAS 0036-8075 10.1126/science.282.5390.902 282, 902 (1998). (Pubitemid 28507515)
    • (1998) Science , vol.282 , Issue.5390 , pp. 902-907
    • Wang, M.D.1    Schnitzer, M.J.2    Yin, H.3    Landick, R.4    Gelles, J.5    Block, S.M.6
  • 61
    • 0020502331 scopus 로고
    • JCLBA3 0021-9525 10.1083/jcb.97.2.542
    • R. B. Nicklas, J. Cell. Biol. JCLBA3 0021-9525 10.1083/jcb.97.2.542 97, 542 (1983).
    • (1983) J. Cell. Biol. , vol.97 , pp. 542
    • Nicklas, R.B.1
  • 62
    • 0041305824 scopus 로고    scopus 로고
    • Structural transitions and elasticity from torque measurements on DNA
    • DOI 10.1038/nature01810
    • Z. Bryant, M. D. Stone, J. Gore, S. B. Smith, N. R. Cozzarelli, and C. Bustamante, Nature (London) NATUAS 0028-0836 10.1038/nature01810 424, 338 (2003). (Pubitemid 36899378)
    • (2003) Nature , vol.424 , Issue.6946 , pp. 338-341
    • Bryant, Z.1    Stone, M.D.2    Gore, J.3    Smith, S.B.4    Cozzarelli, N.R.5    Bustamante, C.6
  • 63
    • 33750621840 scopus 로고    scopus 로고
    • Indirect Readout of DNA Sequence by Proteins: The Roles of DNA Sequence-Dependent Intrinsic and Extrinsic Forces
    • DOI 10.1016/S0079-6603(06)81004-4, PII S0079660306810044, Progress in Nuclei Acid Research and Molecular Biology
    • G. B. Koudelka, S. A. Mauro, and M. Ciubotaru, Prog. Nucleic Acid Res. Mol. Biol. NATUAS 0125-4008 10.1016/S0079-6603(06)81004-4 81, 143 (2006). (Pubitemid 44691673)
    • (2006) Progress in Nucleic Acid Research and Molecular Biology , vol.81 , pp. 143-177
    • Koudelka, G.B.1    Mauro, S.A.2    Ciubotaru, M.3
  • 66
    • 0001470510 scopus 로고    scopus 로고
    • JCCHDD 0192-8651 10.1002/(SICI)1096-987X(199708)18:11< 1354::AID-JCC3> 3.0.CO;2-K
    • A. K. Mazur, J. Comput. Chem. JCCHDD 0192-8651 10.1002/(SICI)1096- 987X(199708)18:11< 1354::AID-JCC3> 3.0.CO;2-K 18, 1354 (1997).
    • (1997) J. Comput. Chem. , vol.18 , pp. 1354
    • Mazur, A.K.1
  • 67
    • 0000039979 scopus 로고    scopus 로고
    • JCPSA6 0021-9606 10.1063/1.479399
    • A. K. Mazur, J. Chem. Phys. JCPSA6 0021-9606 10.1063/1.479399 111, 1407 (1999).
    • (1999) J. Chem. Phys. , vol.111 , pp. 1407
    • Mazur, A.K.1
  • 68
    • 0032576192 scopus 로고    scopus 로고
    • Accurate DNA dynamics without accurate long-range electrostatics
    • DOI 10.1021/ja981498w
    • A. K. Mazur, J. Am. Chem. Soc. JACSAT 0002-7863 10.1021/ja981498w 120, 10928 (1998). (Pubitemid 28507439)
    • (1998) Journal of the American Chemical Society , vol.120 , Issue.42 , pp. 10928-10937
    • Mazur, A.K.1
  • 69
    • 0032495284 scopus 로고    scopus 로고
    • JPCBFK 1520-6106 10.1021/jp972381h
    • A. K. Mazur, J. Phys. Chem. B JPCBFK 1520-6106 10.1021/jp972381h 102, 473 (1998).
    • (1998) J. Phys. Chem. B , vol.102 , pp. 473
    • Mazur, A.K.1
  • 70
    • 80051653158 scopus 로고    scopus 로고
    • See Supplemental Material at
    • See Supplemental Material at http://aps.org/supplemental/10.1103/ PhysRevE.84.021903 for auxiliary figures and details of simulation protocols.
  • 71
    • 0242396923 scopus 로고    scopus 로고
    • 3DNA: A software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures
    • DOI 10.1093/nar/gkg680
    • X.-J. Lu and W. K. Olson, Nucleic Acids Res. NARHAD 0305-1048 10.1093/nar/gkg680 31, 5108 (2003). (Pubitemid 37441878)
    • (2003) Nucleic Acids Research , vol.31 , Issue.17 , pp. 5108-5121
    • Lu, X.-J.1    Olson, W.K.2
  • 73
    • 0031592942 scopus 로고    scopus 로고
    • Structure and conformation of helical nucleic acids: Analysis program (SCHNAaP)
    • DOI 10.1006/jmbi.1997.1346
    • X. J. Lu, M. A. El Hassan, and C. A. Hunter, J. Mol. Biol. JMOBAK 0022-2836 10.1006/jmbi.1997.1346 273, 668 (1997). (Pubitemid 27488808)
    • (1997) Journal of Molecular Biology , vol.273 , Issue.3 , pp. 668-680
    • Lu, X.-J.1    El Hassan, M.A.2    Hunter, C.A.3
  • 74
    • 0033614014 scopus 로고    scopus 로고
    • Resolving the discrepancies among nucleic acid conformational analyses
    • DOI 10.1006/jmbi.1998.2390
    • X.-J. Lu and W. K. Olson, J. Mol. Biol. JMOBAK 0022-2836 10.1006/jmbi.1998.2390 285, 1563 (1999). (Pubitemid 29060456)
    • (1999) Journal of Molecular Biology , vol.285 , Issue.4 , pp. 1563-1575
    • Lu, X.-J.1    Olson, W.K.2
  • 75
    • 54249088052 scopus 로고    scopus 로고
    • SCIEAS 0036-8075 10.1126/science.1158881
    • R. S. Mathew-Fenn, R. Das, and P. A. B. Harbury, Science SCIEAS 0036-8075 10.1126/science.1158881 322, 446 (2008).
    • (2008) Science , vol.322 , pp. 446
    • Mathew-Fenn, R.S.1    Das, R.2    Harbury, P.A.B.3
  • 76
    • 68949114388 scopus 로고    scopus 로고
    • PLEEE8 1539-3755 10.1103/PhysRevE.80.010901
    • A. K. Mazur, Phys. Rev. E PLEEE8 1539-3755 10.1103/PhysRevE.80.010901 80, 010901 (2009).
    • (2009) Phys. Rev. e , vol.80 , pp. 010901
    • Mazur, A.K.1
  • 79
    • 0023204437 scopus 로고
    • Importance of DNA stiffness in protein-DNA binding specificity
    • DOI 10.1038/329263a0
    • M. E. Hogan and R. H. Austin, Nature (London) NATUAS 0028-0836 10.1038/329263a0 329, 263 (1987). (Pubitemid 17128973)
    • (1987) Nature , vol.329 , Issue.6136 , pp. 263-266
    • Hogan, M.E.1    Austin, R.H.2
  • 80
    • 0019488496 scopus 로고
    • Sequence-dependent helical periodicity of DNA
    • DOI 10.1038/292378a0
    • D. Rhodes and A. Klug, Nature (London) NATUAS 0028-0836 10.1038/292378a0 292, 378 (1981). (Pubitemid 11050351)
    • (1981) Nature , vol.292 , Issue.5821 , pp. 378-380
    • Rhodes, D.1    Klug, A.2
  • 81
    • 0019602939 scopus 로고
    • EJBCAI 0014-2956 10.1111/j.1432-1033.1981.tb06389.x
    • F. Strauss, C. Gaillard, and A. Prunell, Eur. J. Biochem EJBCAI 0014-2956 10.1111/j.1432-1033.1981.tb06389.x 118, 215 (1981).
    • (1981) Eur. J. Biochem , vol.118 , pp. 215
    • Strauss, F.1    Gaillard, C.2    Prunell, A.3
  • 86
    • 77957240150 scopus 로고    scopus 로고
    • NARHAD 0305-1048 10.1093/nar/gkq279
    • T. E. Takasuka and A. Stein, Nucleic Acids Res. NARHAD 0305-1048 10.1093/nar/gkq279 38, 5672 (2010).
    • (2010) Nucleic Acids Res. , vol.38 , pp. 5672
    • Takasuka, T.E.1    Stein, A.2
  • 87
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • DOI 10.1038/nrg1655
    • K. D. Robertson, Nat. Rev. Genet. NARHAD 1471-0056 10.1038/nrg1655 6, 597 (2005). (Pubitemid 41044297)
    • (2005) Nature Reviews Genetics , vol.6 , Issue.8 , pp. 597-610
    • Robertson, K.D.1
  • 90
    • 39549090166 scopus 로고    scopus 로고
    • MeCP2 Binding to DNA Depends upon Hydration at Methyl-CpG
    • DOI 10.1016/j.molcel.2007.12.028, PII S1097276508000968
    • K. L. Ho, I. W. McNae, L. Schmiedeberg, R. J. Klose, A. P. Bird, and M. D. Walkinshaw, Mol. Cell. MOCEFL 1097-2765 10.1016/j.molcel.2007.12.028 29, 525 (2008). (Pubitemid 351282541)
    • (2008) Molecular Cell , vol.29 , Issue.4 , pp. 525-531
    • Ho, K.L.1    McNae, I.W.2    Schmiedeberg, L.3    Klose, R.J.4    Bird, A.P.5    Walkinshaw, M.D.6
  • 91
    • 77954659099 scopus 로고    scopus 로고
    • NATUAS 0028-0836 10.1038/nature09147
    • R. K. Chodavarapu, Nature (London) NATUAS 0028-0836 10.1038/nature09147 466, 388 (2010).
    • (2010) Nature (London) , vol.466 , pp. 388
    • Chodavarapu, R.K.1
  • 92
    • 0023650885 scopus 로고
    • NARHAD 0305-1048 10.1093/nar/15.9.3835
    • T. Bestor, Nucleic Acids Res. NARHAD 0305-1048 10.1093/nar/15.9.3835 15, 3835 (1987).
    • (1987) Nucleic Acids Res. , vol.15 , pp. 3835
    • Bestor, T.1
  • 93
    • 0028010888 scopus 로고
    • CELLB5 0092-8674 10.1016/0092-8674(94)90342-5
    • S. Klimasauskas, S. Kumar, R. J. Roberts, and X. Cheng, Cell CELLB5 0092-8674 10.1016/0092-8674(94)90342-5 76, 357 (1994).
    • (1994) Cell , vol.76 , pp. 357
    • Klimasauskas, S.1    Kumar, S.2    Roberts, R.J.3    Cheng, X.4
  • 94
    • 0033066691 scopus 로고    scopus 로고
    • Synthetic muscle promoters: Activities exceeding naturally occurring regulatory sequences
    • DOI 10.1038/6981
    • X. Li, E. M. Eastman, R. J. Schwartz, and R. Draghia-Akli, Nat. Biotechnol. NABIF9 1087-0156 10.1038/6981 17, 241 (1999). (Pubitemid 29122631)
    • (1999) Nature Biotechnology , vol.17 , Issue.3 , pp. 241-245
    • Li, X.1    Eastman, E.M.2    Schwartz, R.J.3    Draghia-Akli, R.4
  • 95
    • 0032580207 scopus 로고    scopus 로고
    • Allosteric effects of DNA on transcriptional regulators
    • DOI 10.1038/31860
    • J. A. Lefstin and K. R. Yamamoto, Nature (London) NATUAS 0028-0836 10.1038/31860 392, 885 (1998). (Pubitemid 28232051)
    • (1998) Nature , vol.392 , Issue.6679 , pp. 885-888
    • Lefstin, J.A.1    Yamamoto, K.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.