Altered brain neurotrophins at birth: Consequence of imbalance in maternal folic acid and vitamin B 12 metabolism

Neuroscience

Volumn 190, Issue , 2011, Pages 127-134

  Sable, P ^a   Dangat, K ^a   Kale, A ^a   Joshi, S ^a  

^a Bharati Vidyapeeth Deemed University   (India)

Author keywords

Brain derived neurotrophic factor (BDNF); Docosahexaenoic acid (DHA); Folic acid; Nerve growth factor (NGF); Vitamin B 12

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYANOCOBALAMIN; FOLIC ACID; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROTROPHIN;

ANIMAL EXPERIMENT; ARTICLE; BRAIN WEIGHT; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENCEPHALE ISOLE; FEMALE; GESTATION PERIOD; MATERNAL NUTRITION; NONHUMAN; NUTRITIONAL HEALTH; PREGNANCY; PREGNANCY OUTCOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT OUTCOME;

ANIMALS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; DIETARY SUPPLEMENTS; FEMALE; FOLIC ACID; NERVE GROWTH FACTOR; PREGNANCY; PRENATAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; RATS; RATS, WISTAR; VITAMIN B 12;

EID: 80051595449     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.05.010     Document Type: Article

References (54)

1. Aid T., Kazantseva A., Piirsoo M., Palm K., Timmusk T. Mouse and rat BDNF gene structure and expression revisited. J Neurosci Res 2007, 85:525-535.
2. Alleva E., Santucci D. Psychosocial vs"Physical" stress situations in rodents and humans: role of neurotrophins. Physiol Behav 2001, 73:313-320.
3. Bartkowska K., Turlejski K., Djavadian R.L. Neurotrophins and their receptors in early development of the mammalian nervous system. Acta Neurobiol Exp 2010, 70:454-467.
4. Beltz B.S., Tlusty M.F., Benton J.L., Sandeman D.C. Omega-3 fatty acids upregulate adult neurogenesis. Neurosci Lett 2007, 415:154-158.
5. Bhate V., Deshpande S., Bhat D., Niranjan J., Ladkat R., Watve S., Fall C., Celeste A., de Jager C.A., Refsum H., Yajnik C. Vitamin B12 status of pregnant Indian women and cognitive function in their 9-year-old children. Food Nutr Bull 2008, 29:249-254.
6. Black M.M. Effects of vitamin B12 and folate deficiency on brain development in children. Food Nutr Bull 2008, 29:S126-S131.
7. Bukowski R., Malone F.D., Porter F.T., Nyberg D.A., Comstock C.H., Hankins G.D., Eddleman K., Gross S.J., Dugoff L., Craigo S.D., Timor-Tritsch I.E., Carr S.R., Wolfe H.M., D'Alton M.E. Preconceptional folate supplementation and the risk of spontaneous preterm birth: a cohort study. PLoS Med 2009, 6:e1000061.
8. Calderon F., Kim H.Y. Docosahexaenoic acid promotes neurite growth in hippocampal neurons. J Neurochem 2004, 90:979-988.
9. Carmel R. Efficacy and safety of fortification and supplementation with vitamin B12: biochemical and physiological effects. Food Nutr Bull 2008, 29:S177-S187.
10. Dagai L., Peri-Naor R., Birk R.Z. Docosahexaenoic acid significantly stimulates immediate early response genes and neurite outgrowth. Neurochem Res 2009, 34:867-875.
11. Dangat K, Kale A, Joshi S (in press) Maternal supplementation of omega 3 fatty acids to micronutrient imbalanced diet improves lactation in rat. Metabolism, in press.
12. Dangat K.D., Mehendale S.S., Yadav H.R., Kilari A.S., Kulkarni A.V., Taralekar V.S., Joshi S.R. Long-chain polyunsaturated fatty acid composition of breast milk in pre-eclamptic mothers. Neonatology 2010, 97:190-194.
13. Das K.P., Chao S.L., White L.D., Haines W.T., Harry G.J., Tilson H.A., Barone S. Differential patterns of nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 mRNA and protein levels in developing regions of rat brain. Neuroscience 2001, 103:739-761.
14. Fagiolini M., Jensen C., Champagne F. Epigenetic influences on brain development and plasticity. Curr Opin Neurobiol 2009, 19:207-212.
15. Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid. Final rule. 21 CFR Parts 136, 137, and 139. Fed. Regist 1996, 61:8781-8807. Food and Drug Administration.
16. Freire W.B., Hertrampf E., Cortes F. Effect of folic acid fortification in Chile: preliminary results. Eur J Pediatr Surg 2000, 10:42-43.
17. Fritsche K.L., Johnston P.V. Rapid autoxidation of fish oil in diets without added antioxidants. J Nutr 1988, 118:425-426.
18. Gallagher E.A.L., Newman J.P., Green L.R., Hanson M.A. The effect of low protein diet in pregnancy on the development of brain metabolism in rat offspring. J Physiol 2005, 568(Pt 2):553-558.
19. Gluckman P.D., Hanson M.A. Living with the past: evolution, development, and patterns of disease. Science 2004, 305:1733-1736.
20. Gonzalez M.J., Gray J.I., Schemmel R.A., Dugan L., Welsch C.W. Lipid peroxidation products are elevated in fish oil diets even in the presence of added antioxidants. J Nutr 1992, 122:2190-2195.
21. Gunnar M., Quevedo K. The neurobiology of stress and development. Annu Rev Psychol 2007, 58:145-173.
22. Gupta A, Puri V, Sharma R, Puri S (in press) Folic acid induces acute renal failure (ARF) by enhancing renal prooxidant state. Exp Toxicol Pathol.
23. Hashimoto M., Tanabe Y., Fujii Y., Hagiwara R., Yamasaki H., Shido O. Mechanism of improvement of spatial cognition with dietary docosahexaenoic acid. Nippon Yakurigaku Zasshi 2002, 120:54-56.
24. Hove D.L., Steinbusch H.W., Scheepens A., Van de Berg W.D., Kooiman L.A., Boosten B.J., Prickaerts J., Blanco C.E. Prenatal stress and neonatal rat brain development. Neuroscience 2006, 137:145-155.
25. Huh C., Danik M., Manseau F., Trudeau L., Williams S. Chronic exposure to nerve growth factor increases acetylcholine and glutamate release from cholinergic neurons of the rat medial septum and diagonal band of broca via mechanisms mediated by p75NTR. J Neurosci 2008, 28:1404-1409.
26. Ikemoto A., Ohishi M., Hata N., Misawa Y., Fujii Y., Okuyama H. Effect of n-3 fatty acid deficiency on fatty acid composition and metabolism of aminophospholipids in rat brain synaptosomes. Lipids 2000, 10:1107-1115.
27. Kale A., Napahde N., Sapkale S., Kamaraju M., Pillai A., Joshi S., Mahadik S. Reduced folic acid, vitamin B12 and docosahexaenoic acid and increased homocysteine and cortisol in never-medicated schizophrenia patients. Psychiatry Res 2010, 175:47-53.
28. Kapczinski F., Frey B.N., Andreazza A.C., Kauer-Sant'Anna M., Cunha A.B., Post R.M. Increased oxidative stress as a mechanism for decreased BDNF levels in acute manic episodes. Rev Bras Psiquiatr 2008, 30:243-245.
29. Kolling J., Scherer E.B., da Cunha A.A., da Cunha M.J., Wyse A.T. Homocysteine induces oxidative-nitrative stress in heart of rats: prevention by folic acid. Cardiovasc Toxicol 2011, 11:67-73.
30. Kulkarni A., Dangat K., Kale A., Sable P., Chavan-Gautam P., Joshi S. Effects of altered maternal folic acid, vitamin B12 and docosahexaenoic acid on placental global DNA methylation patterns in Wistar rats. PLoS One 2011, 6(3):e17706.
31. Kumar N. Neurological presentations of nutritional deficiencies. Neurol Clin 2010, 28:107-170.
32. Lim S.Y., Hoshiba J., Moriguchi T., Salem N. N-3 fatty acid deficiency induced by a modified artificial rearing method leads to poorer performance in spatial learning tasks. Pediatr Res 2005, 58:741-748.
33. Liu Q.R., Lu L., Zhu X.G., Gong J.P., Shaham Y., Uhl G.R. Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine. Brain Res 2006, 1067:1-12.
34. Maisonpierre P., Belluscio L., Friedman B., Alderson R., Wiegand S., Furth M., Lindsay R., Yancopoulos G. NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression. Neuron 1990, 5:501-509.
35. Malouf M., Grimley E.J., Areosa S.A. Folic acid with or without vitamin B12 for cognition and dementia. Cochrane Database Syst Rev 2003, 4. CD004514.
36. Martin R.E., Wickham J.Q., Om A., Sanders J., Ceballos N. Uptake and incorporation of docosahexaenoic acid (DHA) into neuronal cell body and neurite/nerve growth cone lipids: evidence of compartmental DHA metabolism in nerve growth factor-differentiated PC12 cells. Neurochem Res 2000, 25:715-723.
37. Matté C., Mackedanz V., Stefanello F.M., Scherer E.B., Andreazza A.C., Zanotto C., Moro A.M., Garcia S.C., Gonçalves C.A., Erdtmann B., Salvador M., Wyse A.T. Chronic hyperhomocysteinemia alters antioxidant defenses and increases DNA damage in brain and blood of rats: protective effect of folic acid. Neurochem Int 2009, 54:7-13.
38. Metz J., Sikaris K.A., Maxwell E.L., Levin M.D. Changes in serum folate concentrations following voluntary food fortification in Australia. Med J Aust 2002, 176:90-91.
39. Palacios-Pelaez R., Lukiw W.J., Bazan N.G. Omega-3 essential fatty acids modulate initiation and progression of neurodegenerative disease. Mol Neurobiol 2010, 41:367-374.
40. Rao S., Joshi S., Kale A., Hegde M., Mahadik S. Maternal folic acid supplementation to dams on marginal protein level alters brain fatty acid levels of their adult offspring. Metabolism 2006, 55:628-634.
41. Reeves P., Nielsen F., Fahey G. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993, 123:1939-1951.
42. Refsum H. Folate, vitamin B12 and homocysteine in relation to birth defects and pregnancy outcome. Br J Nutr 2001, 85:S109-S113.
43. Roy S, Kale A, Dangat K, Sable P, Kulkarni A, Joshi S (in press) Maternal micronutrients (folic acid and vitamin B12) and omega 3 fatty acids: implications for neurodevelopmental risk in the rat offspring. Brain Dev.
44. Scaccianoce S., Catalani A., Lombardo K., Consoli C., Angelucci L. Maternal glucocorticoid hormone influences nerve growth factor expression in the developing rat brain. Neuroreport 2001, 17:2881-2884.
45. Simopoulos A.P. Essential fatty acids in health and chronic disease. Am J Clin Nutr 1999, 70:560S-569S.
46. Singh R., Kanwar S.S., Sood P.K., Nehru B. Beneficial effects of folic acid on enhancement of memory and antioxidant status in aged rat brain. Cell Mol Neurobiol 2011, 31:83-91.
47. Smith S.E., Kinney H.C., Swoboda K.J., Levi H.L. Subacute combined degeneration of the spinal cord in cblC disorder despite treatment with B12. Mol Genet Metab 2006, 88:138-145.
48. Tolwani R.J., Buckmaster P.S., Varma S., Cosgaya J.M., Wu Y., Suri C., Shooter E.M. BDNF overexpression increases dendrite complexity in hippocampal dentate gyrus. Neuroscience 2000, 114:795-805.
49. Urquiza A.M., Liu S., Sjoberg M. Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science 2000, 290:2140-2144.
50. Veena S.R., Krishnaveni G.V., Srinivasan K., Wills A.K., Muthayya S., Kurpad A.V., Yajnik C.S., Fall C.H. Higher maternal plasma folate but not vitamin B-12 concentrations during pregnancy are associated with better cognitive function scores in 9- to 10-year-old children in South India. J Nutr 2010, 140:1014-1022.
51. Wald D.S., Kasturiratne A., Simmonds M. Effect of folic acid, with or without other B vitamins, on cognitive decline: meta-analysis of randomized trials. Am J Med 2010, 123:522-527.
52. Wu A., Ying Z., Gomez-Pinilla F. Dietary omega-3 fatty acids normalize BDNF levels, reduce oxidative damage, and counteract learning disability after traumatic brain injury in rats. J Neurotrauma 2004, 21:1457-1467.
53. Yajnik C.S., Deshpande S.S., Lubree H.G., Naik S.S., Bhat D.S., Uradey B.S., Deshpande J.A., Rege S.S., Refsum H., Yudkin J.S. Vitamin B12 deficiency and hyperhomocysteinemia in rural and urban Indians. J Assoc Physicians India 2006, 54:775-782.
54. Zou J., Crews F. CREB and NF-kappaB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death. Cell Mol Neurobiol 2006, 26:385-405.