Comitogenic effect of catecholamines on rat cardiac fibroblasts in culture

Cardiovascular Research

Volumn 48, Issue 2, 2000, Pages 274-284

  Leicht, Monika ^a   Greipel, Nora ^a   Zimmer, Heinz Gerd ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Adrenergic (ant)agonists; Cell culture isolation; Protein kinases; Receptors

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; ADRENERGIC RECEPTOR; CARVEDILOL; CATECHOLAMINE DERIVATIVE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EPIDERMAL GROWTH FACTOR; FORSKOLIN; ISOPRENALINE; METOPROLOL; MITOGEN ACTIVATED PROTEIN KINASE; MYELIN BASIC PROTEIN; NORADRENALIN; PHENYLEPHRINE; PLATELET DERIVED GROWTH FACTOR A; PRAZOSIN; PROPRANOLOL; RECEPTOR SUBTYPE; YOHIMBINE;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; FIBROBLAST CULTURE; HEART MUSCLE CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SERUM; WESTERN BLOTTING;

ADRENERGIC BETA-ANTAGONISTS; ANIMAL; CELL DIVISION; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA-BINDING PROTEIN, CYCLIC AMP-RESPONSIVE; ENZYME ACTIVATION; ENZYME INHIBITORS; FEMALE; FIBROBLASTS; FORSKOLIN; MITOGEN-ACTIVATED PROTEIN KINASES; MYELIN BASIC PROTEINS; MYOCARDIUM; NOREPINEPHRINE; P42 MAP KINASE; PHOSPHORYLATION; PROPANOLAMINES; PROPRANOLOL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA-2; STIMULATION, CHEMICAL; SUPPORT, NON-U.S. GOV'T;

EID: 0033774646     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(00)00170-X     Document Type: Article

References (47)

1. Acute effects of catecholamines on function of the rat right heart
2. Alpha- and beta-adrenergic stimulation of protein synthesis in cultured adult ventricular cardiomyocytes
3. Hypertrophic responsiveness to beta 2-adrenoceptor stimulation on adult ventricular cardiomyocytes
4. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype
5. Angiotensin I.I. and serum differentially regulate expression of cyclins, activity of cyclin-dependent kinases, and phosphorylation of retinoblastoma gene product in neonatal cardiac myocytes
6. 1 adrenergic response
7. Alpha 1-adrenergic stimulation of cardiac gene transcription in neonatal rat myocardial cells. Effects on myosin light chain-2 gene expression
8. Transcription of early developmental isogenes in cardiac myocyte hypertrophy
9. The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy
10. Collagen chain mRNAs in isolated heart cells from young and adult rats
11. Differential effects of transforming growth factor-beta 1 and phorbol myristate acetate on cardiac fibroblasts. Regulation of fibrillar collagen mRNAs and expression of early transcription factors
12. Angiotensin I.I. is mitogenic in neonatal rat cardiac fibroblasts
13. Identification of functional angiotensin II receptors on rat cardiac fibroblasts
14. Characterization of angiotensin II receptors in cultured adult rat cardiac fibroblasts
15. Regulation of proliferative response of cardiac fibroblasts by transforming growth factor-beta 1
16. PDGF-AA, a potent mitogen for cardiac fibroblasts from adult rats
17. Beta-adrenergic stimulation of cardiac non-myocytes augments the growth-promoting activity of non-myocyte conditioned medium
18. Effect of norepinephrine on myocardial collagen gene expression and response of cardiac fibroblasts after norepinephrine treatment
19. Nitric oxide, atrial natriuretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in cardiac myocytes and fibroblasts
20. Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene
21. Purification and characterization of a 43-kDa transcription factor required for rat somatostatin gene expression
22. Norepinephrine induces the raf-1 kinase/mitogen-activated protein kinase cascade through both alpha 1- and beta-adrenoceptors
23. Raf-1 kinase activity is necessary and sufficient for gene expression changes but not sufficient for cellular morphology changes associated with cardiac myocyte hypertrophy
24. Depletion of mitogen-activated protein kinase using an antisense oligodeoxynucleotide approach downregulates the phenylephrine-induced hypertrophic response in rat cardiac myocytes
25. Beta-adrenergic agonists stimulate the oxidative pentose phosphate pathway in the rat heart
26. Adult ventricular rat heart muscle cells
27. Culture of the terminally differentiated adult cardiac muscle cell: a light and scanning electron microscope study
28. Labeling of individual amino acid residues in the membrane-embedded F0 part of the F1 F0 ATP synthase from Neurospora crassa. Influence of oligomycin and dicyclohexylcarbodiimide
29. Quantification of proteins dissolved in an electrophoresis sample buffer
30. PDGF-AA effectively stimulates early events but has no mitogenic activity in AKR-2B mouse fibroblasts
31. Differential effects of angiotensin II receptor blockade on pressure-induced left ventricular hypertrophy and fibrosis in rats
32. Significance of myocardial alpha- and beta-adrenoceptors in catecholamine-induced cardiac hypertrophy
33. Rapamycin selectively inhibits angiotensin II-induced increase in protein synthesis in cardiac myocytes in vitro. Potential role of 70-kD S6 kinase in angiotensin II-induced cardiac hypertrophy
34. Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy
35. Beta-adrenergic agonists stimulate the synthesis of noncontractile but not contractile proteins in cultured myocytes isolated from adult rat heart
36. Distinct pathways of Gi- and Gq-mediated mitogen-activated protein kinase activation
37. Dual effect of beta-adrenergic receptors on mitogen-activated protein kinase. Evidence for a beta gamma-dependent activation and a G alpha s- cAMP-mediated inhibition
38. Cell type-specific angiotensin II-evoked signal transduction pathways: critical roles of Gbetagamma subunit. Src family, and Ras in cardiac fibroblasts
39. Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation
40. Inhibition of human cardiac fibroblast mitogenesis by blockade of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
41. Adrenergic receptors. Models for the study of receptors coupled to guanine nucleotide regulatory proteins
42. Role of cyclic nucleotides in growth control
43. Possible involvement of normal p21 H-ras in the insulin/insulin-like growth factor 1 signal transduction pathway
44. Cyclic AMP inhibits mitogen-induced DNA synthesis in hamster fibroblasts, regardless of the signalling pathway involved
45. Early signals in the mitogenic response
46. The cyclic AMP-mediated stimulation of cell proliferation
47. Adrenomedullin stimulates DNA synthesis and cell proliferation via elevation of cAMP in Swiss 3T3 cells