Stress fiber organization regulated by MLCK and Rho-kinase in cultured human fibroblasts

American Journal of Physiology - Cell Physiology

Volumn 280, Issue 6 49-6, 2001, Pages

  Katoh, Kazuo ^a   Kano, Yumiko ^a   Amano, Mutsuki ^c   Kaibuchi, Kozo ^b,c   Fujiwara, Keigi ^d  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Contraction; Myosin light chain kinase; Myosin regulatory light chain; Rho kinase; Stress fiber

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CALMODULIN INHIBITOR; F ACTIN; MYOSIN LIGHT CHAIN KINASE; MYOSIN LIGHT CHAIN KINASE INHIBITOR; RHO KINASE;

ARTICLE; CELL CULTURE; ENZYME ACTIVITY; ENZYME ANALYSIS; FIBER; FIBROBLAST; HUMAN; HUMAN CELL; IMAGE ANALYSIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM; STRESS FIBER;

EID: 0034984503     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2001.280.6.c1669     Document Type: Article

References (25)

1. Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase
2. Myosin II activation promotes neurite retraction during the action of Rho and Rhokinase
3. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)
4. Identification of a putative target for Rho as the serine-threonine kinase protein kinase N
5. Focal adhesions: Transmembrane junction between the extracellular matrix and the cytoskeleton
6. Organization and function of stress fibers in cells in vitro and in situ
7. Cytoskeletal rearrangements and transcriptional activation of c-fos serum response element by Rho-kinase
8. The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase
9. Lateral zone of cell-cell adhesion as the major fluid shear stress-related signal transduction site
10. Macromolecular composition of stress fiber-plasma membrane attachment sites in endothelial cells in situ
11. Rho-kinase mediated contraction of isolated stress fibers
12. Isolation and in vitro contraction of stress fibers
13. Isolation and contraction of the stress fiber
14. Focal adhesion proteins associated with apical stress fibers of human fibroblasts
15. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase during cell migration and cytokinesis
16. Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)
17. Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation
18. A novel serine/threonine kinase binding the ras-related RhoA GTPase which translocates the kinase to peripheral membranes
19. Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
20. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
21. Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D
22. Preservation of differentiated phenotypes in cultured aortic endothelial cells by malotilate and phosphoascorbic acid
23. The effects of HA compound calcium antagonists on delayed cerebral vasospasm in dogs
24. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
25. p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho smll GTPase and is a ligand for profilin