The driver of malignancy in KG-1a leukemic cells, FGFR1OP2-FGFR1, encodes an HSP90 addicted oncoprotein

Cellular Signalling

Volumn 23, Issue 11, 2011, Pages 1758-1766

  Jin, Yixin ^a   Zhen, Yan ^a   Haugsten, Ellen Margrethe ^b   Wiedlocha, Antoni ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

CDC37; Chromosomal translocation; FGFR1 fusion oncoprotein; HSF1; HSP90; Malignant phenotype; Tyrosine kinase

Indexed keywords

CELL CYCLE PROTEIN 37; FIBROBLAST GROWTH FACTOR RECEPTOR 1; HEAT SHOCK PROTEIN 90; HEAT SHOCK TRANSCRIPTION FACTOR 1; HYBRID PROTEIN; ONCOPROTEIN; PROTEIN TYROSINE KINASE; SIRTUIN 1;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; FGFR1 GENE; FGFR1OP2 GENE; FUSION GENE; GENE ACTIVITY; GENE EXPRESSION; GENETIC STABILITY; HUMAN; HUMAN CELL; INHIBITION KINETICS; LEUKEMIA; LEUKEMIA CELL; ONCOGENE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL PROLIFERATION; CHAPERONINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPRECIPITATION; LEUKEMIA, MYELOID; NEOPLASM PROTEINS; ONCOGENE PROTEINS, FUSION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSLOCATION, GENETIC;

EID: 80051469135     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.06.010     Document Type: Article

References (56)

1. Haugsten E.M., Wiedlocha A., Olsnes S., Wesche J. Mol. Cancer Res. 2010, 8(11):1439-1452.
2. Beenken A., Mohammadi M. Nat. Rev. Drug Discov. 2009, 8(3):235-253.
3. Turner N., Grose R. Nat. Rev. Cancer 2010, 10(2):116-129.
4. Furdui C.M., Lew E.D., Schlessinger J., Anderson K.S. Mol. Cell 2006, 21(5):711-717.
5. Cross N.C., Reiter A. Leukemia 2002, 16(7):1207-1212.
6. Delaval B., Lelievre H., Birnbaum D. Leukemia 2005, 19(10):1739-1744.
7. Penserga E.T., Skorski T. Oncogene 2007, 26(1):11-20.
8. Furley A.J., Reeves B.R., Mizutani S., Altass L.J., Watt S.M., Jacob M.C., et al. Blood 1986, 68(5):1101-1107.
9. Grand E.K., Grand F.H., Chase A.J., Ross F.M., Corcoran M.M., Oscier D.G., et al. Genes Chromosomes Cancer 2004, 40(1):78-83.
10. Gu T.L., Goss V.L., Reeves C., Popova L., Nardone J., Macneill J., et al. Blood 2006, 108(13):4202-4204.
11. Popovici C., Zhang B., Gregoire M.J., Jonveaux P., Lafage-Pochitaloff M., Birnbaum D., et al. Blood 1999, 93(4):1381-1389.
12. Patnaik M.M., Tefferi A. Expert. Rev. Mol. Diagn. 2009, 9(5):481-492.
13. Goss V.L., Lee K.A., Moritz A., Nardone J., Spek E.J., Macneill J., et al. Blood 2006, 107(12):4888-4897.
14. Zhen Y., Sorensen V., Jin Y., Suo Z., Wiedlocha A. Oncogene 2007, 26(44):6372-6385.
15. Balch W.E., Morimoto R.I., Dillin A., Kelly J.W. Science 2008, 319(5865):916-919.
16. Pearl L.H., Prodromou C. Annu. Rev. Biochem. 2006, 75:271-294.
17. Taipale M., Jarosz D.F., Lindquist S. Nat. Rev. Mol. Cell Biol. 2010, 11(7):515-528.
18. Vaughan C.K., Gohlke U., Sobott F., Good V.M., Ali M.M., Prodromou C., et al. Mol. Cell 2006, 23(5):697-707.
19. Caplan A.J., Mandal A.K., Theodoraki M.A. Trends Cell Biol. 2007, 17(2):87-92.
20. Gray P.J., Prince T., Cheng J., Stevenson M.A., Calderwood S.K. Nat. Rev. Cancer 2008, 8(7):491-495.
21. Mandal A.K., Lee P., Chen J.A., Nillegoda N., Heller A., DiStasio S., et al. J. Cell Biol. 2007, 176(3):319-328.
22. Karnitz L.M., Felts S.J. Sci. STKE 2007, 2007(385):e22.
23. Whitesell L., Lindquist S.L. Nat. Rev. Cancer 2005, 5(10):761-772.
24. Calderwood S.K., Khaleque M.A., Sawyer D.B., Ciocca D.R. Trends Biochem. Sci. 2006, 31(3):164-172.
25. Trepel J., Mollapour M., Giaccone G., Neckers L. Nat. Rev. Cancer 2010, 10(8):537-549.
26. Dai C., Whitesell L., Rogers A.B., Lindquist S. Cell 2007, 130(6):1005-1018.
27. Solimini N.L., Luo J., Elledge S.J. Cell 2007, 130(6):986-988.
28. Luo J., Solimini N.L., Elledge S.J. Cell 2009, 136(5):823-837.
29. Grammatikakis N., Lin J.H., Grammatikakis A., Tsichlis P.N., Cochran B.H. Mol. Cell. Biol. 1999, 19(3):1661-1672.
30. Grbovic O.M., Basso A.D., Sawai A., Ye Q., Friedlander P., Solit D., et al. Proc. Natl. Acad Sci. U. S. A. 2006, 103(1):57-62.
31. Gould C.M., Kannan N., Taylor S.S., Newton A.C. J. Biol. Chem. 2009, 284(8):4921-4935.
32. Mohammadi M., Froum S., Hamby J.M., Schroeder M.C., Panek R.L., Lu G.H., et al. EMBO J. 1998, 17(20):5896-5904.
33. Zhang T., Hamza A., Cao X., Wang B., Yu S., Zhan C.G., et al. Mol. Cancer Ther. 2008, 7(1):162-170.
34. Zhang T., Li Y., Yu Y., Zou P., Jiang Y., Sun D. J. Biol. Chem. 2009, 284(51):35381-35389.
35. Salminen A., Lehtonen M., Paimela T., Kaarniranta K. Biochem. Biophys. Res. Commun. 2010, 394(3):439-442.
36. Mizushima N., Levine B., Cuervo A.M., Klionsky D.J. Nature 2008, 451(7182):1069-1075.
37. Shen S., Zhang P., Lovchik M.A., Li Y., Tang L., Chen Z., et al. J. Cell Biol. 2009, 185(4):629-639.
38. Vaughan C.K., Mollapour M., Smith J.R., Truman A., Hu B., Good V.M., et al. Mol. Cell. 2008, 31(6):886-895.
39. Miyata Y. Cell Mol. Life Sci. 2009, 66(11-12):1840-1849.
40. Ruzzene M., Penzo D., Pinna L.A. Biochem. J. 2002, 364(Pt 1):41-47.
41. Pagano M.A., Bain J., Kazimierczuk Z., Sarno S., Ruzzene M., Di M.G., et al. Biochem. J. 2008, 415(3):353-365.
42. Whitesell L., Lindquist S. Expert Opin. Ther. Targets 2009, 13(4):469-478.
43. Calderwood S.K., Khaleque M.A., Sawyer D.B., Ciocca D.R. Trends Biochem. Sci. 2006, 31(3):164-172.
44. Westerheide S.D., Anckar J., Stevens S.M., Sistonen L., Morimoto R.I. Science 2009, 323(5917):1063-1066.
45. Saunders L.R., Verdin E. Science 2009, 323(5917):1021-1022.
46. Guarente L. Science 2009, 324(5932):1281-1282.
47. Donmez G., Guarente L. Aging Cell 2010, 9(2):285-290.
48. Solomon J.M., Pasupuleti R., Xu L., McDonagh T., Curtis R., DiStefano P.S., et al. Mol. Cell. Biol. 2006, 26(1):28-38.
49. Smith J.R., Clarke P.A., de B.E., Workman P. Oncogene 2009, 28(2):157-169.
50. Liu T., Liu P.Y., Marshall G.M. Cancer Res. 2009, 69(5):1702-1705.
51. An W.G., Schulte T.W., Neckers L.M. Cell Growth Differ. 2000, 11(7):355-360.
52. Shiotsu Y., Neckers L.M., Wortman I., An W.G., Schulte T.W., Soga S., et al. Blood 2000, 96(6):2284-2291.
53. Gorre M.E., Ellwood-Yen K., Chiosis G., Rosen N., Sawyers C.L. Blood 2002, 100(8):3041-3044.
54. Peng C., Brain J., Hu Y., Goodrich A., Kong L., Grayzel D., et al. Blood 2007, 110(2):678-685.
55. Meng L., Gabai V.L., Sherman M.Y. Oncogene 2010, 29(37):5204-5213.
56. Zaarur N., Gabai V.L., Porco J.A., Calderwood S., Sherman M.Y. Cancer Res. 2006, 66(3):1783-1791.