Therapeutic treatments of mtDNA diseases at the earliest stages of human development

Mitochondrion

Volumn 11, Issue 5, 2011, Pages 820-828

  Chiaratti, Marcos Roberto ^a,b   Meirelles, Flávio Vieira ^b   Wells, Dagan ^a   Poulton, Joanna ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Cytoplasmic transfer; Mitochondria; Mitochondrial disease; MtDNA; Nuclear transfer; Pre implantation genetic diagnosis

Indexed keywords

DNA POLYMERASE; GA BINDING PROTEIN; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MITOCHONDRIAL TRANSCRIPTION FACTOR B; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA;

CELL INTERACTION; CELL NUCLEUS TRANSPLANTATION; CELL TRANSPORT; DEVELOPMENTAL STAGE; DISEASE ASSOCIATION; DISEASE TRANSMISSION; ENERGY YIELD; GENE DOSAGE; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; INHERITANCE; INTRACELLULAR SIGNALING; MITOCHONDRIAL DNA DISORDER; MITOCHONDRIAL DNA REPLICATION; MOLECULAR DYNAMICS; OXIDATIVE PHOSPHORYLATION; PATHOLOGY; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVIEW; TREATMENT PLANNING;

ANIMALS; CYTOPLASM; DNA, MITOCHONDRIAL; HEREDITY; HUMANS; MITOCHONDRIAL DISEASES; MUTATION; NUCLEAR TRANSFER TECHNIQUES; PREIMPLANTATION DIAGNOSIS; SELECTION, GENETIC;

EID: 79961208395     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2010.11.004     Document Type: Review

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